Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis

Pancreatology

Volumn 5, Issue 4-5, 2005, Pages 380-386

  Hardman, J ^b   Shields, C ^a   Schofield, D ^b   McMahon, R ^b   Redmond, H P ^a   Siriwardena, A K ^b  

^a University College Cork and INFANT Centre   (Ireland)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Antioxidants; Pancreatitis

Indexed keywords

ACETYLCYSTEINE; AMYLASE; ANTIOXIDANT; ARGININE; ASCORBIC ACID; MYELOPEROXIDASE; SELENIUM; SODIUM CHLORIDE;

ACINAR CELL; ACUTE PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGRANULATION; EDEMA; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HISTOLOGY; INFLAMMATORY CELL; LUNG INJURY; LUNG LAVAGE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PANCREAS INJURY; PRIORITY JOURNAL; RANDOMIZATION; RAT; SUPPLEMENTATION;

EID: 23844477620     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000086538     Document Type: Article

References (34)

1. Powell JJ, Fearon KCH, Siriwardena AK: Current concepts of the pathophysiology and treatment of severe acute pancreatitis. Br J Intensive Care. 2000;10:51-59.
2. de Beaux AC, Goldie AS, Ross JA, Carter DC, Fearon KC: Serum concentration of inflammatory mediators related to organ failure in patients with acute pancreatitis. Br J Surg 1996;83:349-353.
3. Pezzilli R, Billi P, Miniero R, Barakat B: Serum interleukin-10 in human acute pancreatitis. Dig Dis Sci 1997;42:469-472.
4. Pezzilli R, Billi P, Miniero R, Fiocchi M, Cappelletti O, Morselli-Labate AM, Barkat B, Sprovieri G, Miglioli M: Serum interleukin-6, interleukin-8, and beta2-microglobulin in early assessment of severity of acute pancreatitis. Comparison with C-reactive protein. Dig Dis Sci 1995;40:2341-2348.
5. Wilson C, Heads A, Shenkin A, Imrie CW: C-reactive protein, antiproteases and complement factors as objective markers of severity in acute pancreatitis. Br J Surg 1989;76:177-181.
6. Rinderknecht H: Genetic determinants of mortality in acute necrotizing pancreatitis. Int J Pancreatol 1994;16:11-15.
7. Toyama MT, Ashley SW, Reber HA: Pathophysiologic basis of management; in Howard J, Idezuki Y, Ihse I, Prinz R (eds): Surgical Diseases of the Pancreas, ed3. Baltimore, Williams & Wilkins, 1998, pp 199-206.
8. Simms HH, D'Amico R: Polymorphonuclear leukocyte dysregulation during the systemic inflammatory response syndrome. Blood 1994;83:1398-1407.
9. Widdison AL, Cunningham S: Immune function early in acute pancreatitis. Br J Surg 1996;83:633-636.
10. Powell JJ, Siriwardena AK, Fearon KCH, Ross JA: Endothelial-derived selectins in the development of organ dysfunction in acute pancreatitis. Crit Care Med 2001;29:567-572.
11. Fu K, Sarras MP Jr, De Lisle RC: Andrews GK: Expression of oxidative stress response genes and cytokine genes during caerulein-induced acute pancreatitis. Am J Physiol 1997;273:G696-G705.
12. Rau B, Poch B, Gansauge F, Bauer A, Nussler AK, Nevalainen T, Schoenberg MH, Beger HG: Pathophysiologic role of oxygen free radicals in acute pancreatitis. Ann Surg 2000;231:352-360.
13. Braganza JM, Scott P, Bilton D, et al: Evidence for early oxidative stress in acute pancreatitis: Clues for correction. Int J Pancreatol 1995;17: 69-81.
14. Curran FJM, Sattar N, Talwar D, Baxter JN, Imrie CW: Relationship of carotenoid and vitamins A and E with the acute inflammatory response in acute pancreatitis. Br J Surg 2000;87:301-305.
15. Bonham MJ, Abu-Zidan FM, Simovic MO, Sluis KB, Wilkinson A, Winterbourn CC, Windsor JA: Early ascorbic acid depletion is related to the severity of acute pancreatitis. Br J Surg 1999;86:1296-1301.
16. Sweiry JH, Shibuya I, Asada N, Niwa K, Doolabh K, Habara Y, Kanno T, Mann GE: Acute oxidative stress modulates secretion and repetitive Ca2+ spiking in rat exocrine pancreas. Biochim Biophys Acta 1999;1454:19-30.
17. Czako L, Takacs T, Varga IS, Tiszlavicz L, Hai DQ, Hegyi P, Matkovics B, Lonovics J: Involvement of oxygen-derived free radicals in L-arginine-induced acute pancreatitis. Dig Dis Sci 1998;43:1770-1777.
18. Czako L, Takacs T, Varga IS, Tiszlavicz L, Hai DQ, Hegyi P, Matkovics B, Lonovics J: Oxidative stress in distant organs and the effects of allopurinol during experimental acute pancreatitis. Int J Pancreatol 2000;3:209-216.
19. Tani S, Itoh H, Okabayashi Y, Nakamura T, Fujii M, Fujisawa T, Koide M, Otsuki M: New model of acute necrotizing pancreatitis induced by excessive doses of arginine in rats. Dig Dis Sci 1990;35:367-374.
20. Delaney CP, McGeeney KF, Dervan P, Fitzpatrick JM: Pancreatic atrophy: A new model using serial intra-peritoneal injections of L-arginine. Scand J Gastroenterol 1993;28:1086-1090.
21. Shields CJ, Winter DC, Sookhai S, Ryan L, Kirwan WO, Redmond HP: Hypertonic saline attenuates end-organ damage in an experimental model of acute pancreatitis. Br J Surg 2000;87:1336-1340.
22. Goodle HF, Webster NR: Free radicals and antioxidants in sepsis. Crit Care Med 1993;21:1770-1775.
23. Bulger EM, Maier RV: Antioxidants in critical illness. Arch Surg 2001;136:1201-1207.
24. Braganza J: Towards a novel treatment strategy for acute pancreatitis. Digestion 2001;63:69-81.
25. Diehl KH, Hull R, Morton D, Pfister R, Rabemampianina Y, Smith D, Vidal JM, van de Vorstenbosch C: A good practice guide to the administration of substances and removal of blood, including routes and volumes. J Appl Toxicol 2001;21:15-23.
26. Liau LS, Lee BL, New AL, Ong CN: Determination of plasma ascorbic acid by high-performance liquid chromatography with ultraviolet and electrochemical detection. J Chromatogr 1993;612:63-70.
27. Macpherson AK, Sampson B, Diplock AT: Comparison of methods for the detection of selenium in biological fluids. Analyst 1988;113:281-283.
28. Iversen SA, Cawood P, Dormandy TL: A method for the measurement of a diene-conjugated derivative of linoleic acid, 18:2(9,11), in serum phospholipids, and possible origins. Ann Clin Biochem 1985;22:137-140.
29. O'Donovan DA, Kelly CJ, Abdih H, Bouchier-Hayes D, Watson RW, Redmond HP, Burke PE, Bouchier-Hayes DA: Role of nitric oxide in lung injury associated with experimental acute pancreatitis. Br J Surg 1995;82:1122-1126.
30. Angle N, Hoyt DB, Coimbra R, Hoyt DB, Simons RK, Junger WG, Wolf P, Loomis W, Evers MF: Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after haemorrhagic shock. Shock 1998;9:164-170.
31. Rakonczay Z Jr, Takacs T, Ivanyi B, et al: The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats. Pancreas 2002;24:83-89.
32. Angstwurm MW, Schottdorf J, Schopohl J, Gaertner R: Selenium replacement in patients with severe systemic inflammatory response syndrome improves clinical outcome. Crit Care Med 1999;27:1807-1813.
33. Demols A, Van Laethem JL, Quertinmont E, Legros F, Louis H, Le Moine O, Deviere J: N-acetylcysteine decreases severity of acute pancreatitis in mice. Pancreas 2000:20;161-169.
34. Nathens AB, Neff MJ, Jurkovich GJ, Klotz P, Farver K, Ruzinski JT, Radella F, Garcia I, Maier RV: Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg 2002;236:814-822.