Lamivudine permeability study: A comparison between PAMPA, ex vivo and in situ Single-Pass Intestinal Perfusion (SPIP) in rat jejunum

European Journal of Pharmaceutical Sciences

Volumn 48, Issue 4-5, 2013, Pages 781-789

  Reis, J M ^a   Dezani, A B ^a   Pereira, T M ^a   Avdeef, A ^b   Serra, C H R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b In ADME Research   (United States)

Author keywords

Franz cell; In situ perfusion; Jejunum ex vivo; Lamivudine; PAMPA; Permeability

Indexed keywords

CHOLESTEROL; LAMIVUDINE; PHOSPHATIDYLCHOLINE; PLASMA PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL MEMBRANE; CANNULATION; CELL STRAIN CACO 2; CONTROLLED STUDY; EX VIVO STUDY; FLOW RATE; IN VITRO STUDY; INTESTINE PERFUSION; JEJUNUM; MALE; MDCK CELL; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SINGLE PASS INTESTINAL PERFUSION; WISTAR RAT;

ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL TRANSPORT; HUMANS; JEJUNUM; LAMIVUDINE; MALE; MODELS, BIOLOGICAL; PERFUSION; PERMEABILITY; RATS; RATS, WISTAR;

EID: 84873711057     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.12.025     Document Type: Article

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