Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals

Life Sciences

Volumn 88, Issue 21-22, 2011, Pages 959-971

  Pal, Dhananjay ^a   Kwatra, Deep ^a   Minocha, Mukul ^a   Paturi, Durga K ^a   Budda, Balasubrahmanyam ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Antiretrovirals agents; Breast cancer resistance protein; Cytochrome P 450; Multidrug resistance associated protein; P glycoprotein; Protease inhibitors and drugs of abuse

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ABACAVIR; AMPHETAMINE; AMPRENAVIR; ANTIRETROVIRUS AGENT; ATAZANAVIR; BENZODIAZEPINE; BREAST CANCER RESISTANCE PROTEIN; COCAINE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DARUNAVIR; DELAVIRDINE; DIAMORPHINE; DIDANOSINE; DRUG METABOLIZING ENZYME; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; FOSAMPRENAVIR; GLYCOPROTEIN P; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; INDINAVIR; KETOCONAZOLE; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; METHADONE; METHAMPHETAMINE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; NELFINAVIR; NEVIRAPINE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; OPIATE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; TENOFOVIR DISOPROXIL; TIPRANAVIR; UNINDEXED DRUG; ZIDOVUDINE;

ALCOHOL ABUSE; AREA UNDER THE CURVE; DRUG ABSORPTION; DRUG ABUSE; DRUG ALCOHOL INTERACTION; DRUG INTERACTION; DRUG METABOLISM; DRUG RESPONSE; GENE MUTATION; GENETIC POLYMORPHISM; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PREGNANT WOMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN INTERACTION; REVIEW; SUBSTANCE ABUSE; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; ATP-BINDING CASSETTE TRANSPORTERS; BENZODIAZEPINES; COCAINE; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; FEMALE; HIV INFECTIONS; HUMANS; METHAMPHETAMINE; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PREGNANCY; RITONAVIR; SUBSTANCE-RELATED DISORDERS;

EID: 79956190810     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.09.012     Document Type: Review

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