A novel design of artificial membrane for improving the PAMPA model

Pharmaceutical Research

Volumn 25, Issue 7, 2008, Pages 1511-1520

  Chen, Xiaoxi ^a   Murawski, Anthony ^a   Patel, Karishma ^b   Crespi, Charles L ^a   Balimane, Praveen V ^b  

^a BD Biosciences   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Caco 2; Drug absorption; High throughput screening; Parallel artificial membrane permeability assay (PAMPA); Permeability

Indexed keywords

ACEBUTOLOL; ACICLOVIR; ALPRENOLOL; AMILORIDE; ATENOLOL; CAFFEINE; DESIPRAMINE; DICLOFENAC; FAMOTIDINE; FUROSEMIDE; HYDROCHLOROTHIAZIDE; IBUPROFEN; INDOMETACIN; KETOPROFEN; METOPROLOL; NADOLOL; NAPROXEN; ORGANIC SOLVENT; PHENAZONE; PHENYTOIN; PINDOLOL; RANITIDINE; SALAZOSULFAPYRIDINE; SULPIRIDE; TERBUTALINE; THEOPHYLLINE; TIMOLOL; UNINDEXED DRUG; VERAPAMIL; WARFARIN;

ARTICLE; ARTIFICIAL MEMBRANE; CELL STRAIN CACO 2; LIPID MEMBRANE; LIPID TRILAYER; MEMBRANE PERMEABILITY; MEMBRANE STABILIZATION; PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY; POROSITY; PREDICTION; PRIORITY JOURNAL; PROCESS DESIGN; STORAGE; VALIDATION STUDY;

ABSORPTION; ALGORITHMS; BUFFERS; CACO-2 CELLS; DRUG DESIGN; HUMANS; LIPIDS; MEMBRANES, ARTIFICIAL; MODELS, CHEMICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; SOLVENTS;

EID: 44749090398     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-007-9517-8     Document Type: Article

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