Human oral drugs absorption is correlated to their in vitro uptake by brush border membrane vesicles

International Journal of Pharmaceutics

Volumn 336, Issue 1, 2007, Pages 115-121

  Oulianova, Nathalie ^a   Cheng, Deping ^b   Huebert, Norman ^b   Chen, Yanmin ^b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Absorption; BBMV; In vivo in vitro correlation; Transport

Indexed keywords

ACETYLSALICYLIC ACID; AMPICILLIN; ATROPINE; AZLOCILLIN; BROMPHENIRAMINE; CEFADROXIL; CEFALEXIN; CIMETIDINE; DOXORUBICIN; FAMOTIDINE; LAMIVUDINE; LISINOPRIL; MANNITOL; MERCAPTOPURINE; METACYCLINE; NADOLOL; NALOXONE; OUABAIN; PARACETAMOL; PHENAZONE; PHENOLSULFONPHTHALEIN; PIRENZEPINE; PROPRANOLOL; TUBOCURARINE CHLORIDE; ZIDOVUDINE;

ANIMAL TISSUE; ARTICLE; BRUSH BORDER VESICLE; DRUG ABSORPTION; DRUG RESEARCH; DRUG UPTAKE; FALSE POSITIVE RESULT; IN VITRO STUDY; INTESTINE CELL; MEMBRANE BINDING; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; PROTEIN BINDING;

ACETAMINOPHEN; ADMINISTRATION, ORAL; ANIMALS; AZLOCILLIN; BIOLOGICAL TRANSPORT, ACTIVE; CEFADROXIL; DOXORUBICIN; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINE, SMALL; LAMIVUDINE; MANNITOL; OSMOLAR CONCENTRATION; OUABAIN; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PHENOLSULFONPHTHALEIN; RABBITS; ZIDOVUDINE;

EID: 34047267990     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.11.045     Document Type: Article

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