Parallel artificial membrane permeability assay (PAMPA) - is it better than Caco-2 for human passive permeability prediction?

Mini-Reviews in Medicinal Chemistry

Volumn 10, Issue 11, 2010, Pages 1071-1076

  Reis, J M ^a   Sinko B ^b   Serra, C H R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Artificial membrane; BCS; Lipid composition; PAMPA; UWL

Indexed keywords

AMILORIDE; ATENOLOL; CARBAMAZEPINE; CIMETIDINE; DESIPRAMINE; FUROSEMIDE; HYDROCHLOROTHIAZIDE; KETOPROFEN; METOPROLOL; NAPROXEN; PHENAZONE; PIROXICAM; PROPRANOLOL; RANITIDINE; TERBUTALINE; VERAPAMIL;

ARTICLE; ARTIFICIAL MEMBRANE; ASSAY; CELL STRAIN CACO 2; DRUG PENETRATION; HUMAN; INCUBATION TEMPERATURE; INTERMETHOD COMPARISON; JEJUNUM; LIPID COMPOSITION; MEMBRANE MODEL; MEMBRANE PERMEABILITY; NONHUMAN; PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY; PASSIVE TRANSPORT; PH;

EID: 77956638705     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557511009011071     Document Type: Article

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