Genetics of canine diabetes mellitus: Are the diabetes susceptibility genes identified in humans involved in breed susceptibility to diabetes mellitus in dogs?

Veterinary Journal

Volumn 195, Issue 2, 2013, Pages 139-147

  Catchpole, Brian ^a   Adams, Jamie P ^b   Holder, Angela L ^a   Short, Andrea D ^c   Ollier, William E R ^c   Kennedy, Lorna J ^c  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b BOEHRINGER INGELHEIM LTD   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Canine breeds; Diabetes mellitus; Dog leucocyte antigen; Insulin; Major histocompatibility complex; Susceptibility genes

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HLA DQ ANTIGEN; HLA DRB1 ANTIGEN; LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ABCC8 GENE; ALLELE; AUTOSOMAL DOMINANT DISORDER; BREEDING; DIABETES MELLITUS; DISEASE RESISTANCE; DLA DQA1 GENE; DLA GENE; DOG; GCK GENE; GENE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HEREDITY; HETEROZYGOSITY; HLA DQ GENE; HNF1A GENE; HNF4A GENE; HUMAN; IMMUNE RESPONSE; INS GENE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; KCNJ11 GENE; LATENT AUTOIMMUNE DIABETES OF ADULT; MAJOR HISTOCOMPATIBILITY COMPLEX; MONOGENIC DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PATHOGENESIS; PDX1 GENE; PEDIGREE; PREGNANCY DIABETES MELLITUS; PROMOTER REGION; PTPN 22 GENE; REVIEW; SEX DIFFERENCE; VARIABLE NUMBER OF TANDEM REPEAT;

ANIMALS; DIABETES MELLITUS; DOG DISEASES; DOGS; GENETIC PREDISPOSITION TO DISEASE; HUMANS;

ANIMALIA; CANIS FAMILIARIS;

EID: 84873163787     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2012.11.013     Document Type: Review

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