Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele

Tissue Antigens

Volumn 68, Issue 1, 2006, Pages 82-86

  Kennedy, L J ^a,l   Quarmby, S ^a   Happ, G M ^b   Barnes, A ^c   Ramsey, I K ^d   Dixon, R M ^d   Catchpole, B ^e   Rusbridge, C ^f   Graham, P A ^g   Hillbertz, N S ^h   Roethel, C ⁱ   Dodds, W J ^j   Carmichael, N G ^k   Ollier, W E R ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF ALASKA FAIRBANKS   (United States)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

^e ROYAL VETERINARY COLLEGE   (United Kingdom)

^f Stone Lion Veterinary Centre   (United Kingdom)

^g Northwest Laboratories   (United Kingdom)

^h SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

ⁱ Rhodesian Ridgeback Club of the United States ^*  (United States)

^j Hemopet Pet Life Line   (United States)

^k Idexx   (United Kingdom)

^l Stopford Building   (United Kingdom)

more..

Author keywords

DLA; Dogs; Hypothyroidism; MHC

Indexed keywords

GENOMIC DNA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLELE; ARTICLE; BREED; CONTROLLED STUDY; DOG; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC RISK; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HYPOTHYROIDISM; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ALLELES; ANIMALS; DOG DISEASES; DOGS; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYPOTHYROIDISM;

CANIS FAMILIARIS;

EID: 33745171071     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2006.00614.x     Document Type: Article

References (31)

1. Kirkness EF Bafna V Halpern AL et al. The dog genome: survey sequencing and comparative analysis. Science 2003 : 301 : 1898 903.
2. Lindblad-Toh K Wade CM Mikkelsen TS et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 2005 : 438 : 803 19.
3. Ostrander EA Wayne RK. The canine genome. Genome Res 2005 : 15 : 1706 16.
4. Happ GM. Thyroiditis - A model Canine Autoimmune Disease. Advances in Veterinary Science and Comparative Medicine, 1995 : 39 : 97 139.
5. Scott-Moncrieff JCR Guptill-Yoran L. Hypothyroidism. In : Ettinger SJ Feldman EC, eds. Textbook of Veterinary Internal Medicine 6th edn, W. B. Saunders Company : Philadelphia. 2005, 1535 43.
6. Lucke VM Gaskell CJ Wotton PR. Thyroid pathology in canine hypothyroidism. J Comp Pathol 1983 : 93 : 415 21.
7. Beierwaltes WH Nishiyama RH. Dog thyroiditis: occurrence and similarity to Hashimoto's struma. Endocrinology 1968 : 83 : 501 8.
8. Mizejewski GJ Baron J Poissant G. Immunologic investigations of naturally occurring canine thyroiditis. J Immunol, 1971 : 107 : 1152 60.
9. Nachreiner RF Refsal KR Graham PA et al. Prevalence of serum thyroid hormone autoantibodies in dogs with clinical signs of hypothyroidism. J Am Vet Med Assoc 2002 : 220 : 466 71.
10. Panciera DL. Hypothyroidism in dogs - 66 cases (1987-1992). J Am Vet Med Assoc 1994 : 204 : 761 67.
11. Vajner L. Lymphocytic thyroiditis in beagle dogs in a breeding colony: findings of serum autoantibodies. Vet Med (Czech) 1997 : 42 : 333 8.
12. Dixon RM Mooney CT. Canine serum thyroglobulin autoantibodies in health, hypothyroidism and non-thyroidal illness. Res Vet Sci 1999 : 66 : 243 6.
13. Benjamin SA Stephens LC Hamilton BF et al. Associations between lymphocytic thyroiditis, hypothyroidism, and thyroid neoplasia in Beagles. Vet Pathol 1996 : 33 : 486 94.
14. Haines DM Lording PM Penhale WJ. Survey of thyroglobulin autoantibodies in dogs. Am J Vet Res 1984 : 45 : 1493 97.
15. Kennedy LJ Huson HJ Leonard J et al. Association of Hypothyroid disease in Doberman Pinscher dogs with a rare Major Histocompatibility Complex DLA class II haplotype. Tissue Antigens 2006 : 67 : 53 6.
16. Farid NR. Understanding the genetics of autoimmune thyroid disease - Still an elusive goal. J Endocrinol Metab 1992 : 74 : 495A 496A.
17. Kennedy LJ Carter SD Barnes A et al. Nine new dog DLA-DRBI alleles identified by sequence based typing. Immunogenetics 1998 : 48 : 296 301.
18. Kennedy LJ Carter SD Barnes A et al. DLA-DRBI polymorphisms in dogs defined by Sequence Specific Oligonucleotide Probes (SSOP). Tissue Antigens 1999 : 53 : 184 9.
19. Kennedy LJ Carter SD Barnes A et al. DLA-DQA1 polymorphisms in dogs defined by Sequence Specific Oligonucleotide Probes (SSOP). Tissue Antigens 2000 : 55 : 257 61.
20. Kennedy LJ Hall LS Carter SD et al. Identification of further DLA-DRB1 and DQA1 alleles in the dog Eur J Immunogenet 2000 : 27 : 25 8.
21. Kennedy LJ Altet L Angles JM et al. Nomenclature for factors of the Dog Major Histocompatibility System (DLA), 1998: First report of the ISAG DLA Nomenclature Committee. Tissue Antigens 1999 : 54 : 312 21.
22. Kennedy LJ Angles JM Barnes A et al. Nomenclature for factors of the dog major histocompatibility system (DLA), 2000: Second report of the ISAG DLA Nomenclature Committee. Tissue Antigens 2001 : 58 : 55 70.
23. Kennedy LJ Barnes A Short A, Canine DLA diversity. 14th IHIWS report. Tissue Antigens 2006. In press.
24. Wagner JL Burnett RC DeRose SA et al. Molecular analysis and polymorphism of the DLA-DQA gene. Tissue Antigens 1996 : 48 : 199 204.
25. Kennedy LJ Barnes A Happ GM et al. Evidence for extensive DLA polymorphism in different dog populations. Tissue Antigens 2002 : 60 : 43 52.
26. Shi Y Zou M Robb D et al. Typing for major histocompatibility complex class II antigens in thyroid tissue blocks: association of Hashimoto's thyroiditis with HLA-DQA0301 and DQB0201 alleles. J Clin Endocrinol Metab 1992 : 75 : 943 6.
27. Karseladze Ts E Meunargiia VV Metreveli DS et al. [The association of autoimune thyroiditis with HLA-B8 in the Georgian population]. Georgian Med News 2005 : 59 61.
28. Tandon N Zhang L Weetman AP. HLA associations with Hashimoto's thyroiditis. Clin Endocrinol (Oxf) 1991 : 34 : 383 6.
29. Bougacha-Elleuch N Rebai A Mnif M et al. Analysis of MHC genes in a Tunisian isolate with autoimmune thyroid diseases: implication of TNF -308 gene polymorphism. J Autoimmune 2004 : 23 : 75 80.
30. Dittmar M Kahaly GJ. Immunoregulatory and susceptibility genes in thyroid and polyglandular autoimmunity. Thyroid 2005 : 15 : 239 50.
31. Chistiakov DA Turakulov RI. CTLA-4 and its role in autoimmune thyroid disease. J Mol Endocrinol 2003 : 31 : 21 36.