메뉴 건너뛰기




Volumn 32, Issue 24, 2012, Pages 8317-8330

Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; DIPHTHERIA TOXIN; NEURON SPECIFIC NUCLEAR PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; TAMOXIFEN;

EID: 84862265936     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1053-12.2012     Document Type: Article
Times cited : (101)

References (53)
  • 2
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett MH, Prineas JW (2004) Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 55:458-468.
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 4
    • 0015842080 scopus 로고
    • Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone
    • BlakemoreWF (1973) Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone. J Neurol Sci 20:63-72.
    • (1973) J Neurol Sci , vol.20 , pp. 63-72
    • Blakemore, W.F.1
  • 6
    • 0034878448 scopus 로고    scopus 로고
    • Understanding the mode of action of diphtheria toxin: A perspective on progress during the 20th century
    • Collier RJ (2001) Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century. Toxicon 39:1793-1803.
    • (2001) Toxicon , vol.39 , pp. 1793-1803
    • Collier, R.J.1
  • 9
    • 0032031635 scopus 로고    scopus 로고
    • Myelin galactolipids are essential for proper node of Ranvier formation in the CNS
    • Dupree JL, Coetzee T, Blight A, Suzuki K, Popko B (1998) Myelin galactolipids are essential for proper node of Ranvier formation in the CNS. J Neurosci 18:1642-1649.
    • (1998) J Neurosci , vol.18 , pp. 1642-1649
    • Dupree, J.L.1    Coetzee, T.2    Blight, A.3    Suzuki, K.4    Popko, B.5
  • 13
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-the plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS (2006) Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med 354:942-955.
    • (2006) N Engl J Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 14
    • 0026732723 scopus 로고
    • Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression
    • Gow A, Friedrich VL Jr, Lazzarini RA (1992) Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression. J Cell Biol 119:605-616.
    • (1992) J Cell Biol , vol.119 , pp. 605-616
    • Gow, A.1    Friedrich Jr., V.L.2    Lazzarini, R.A.3
  • 15
    • 4444238267 scopus 로고    scopus 로고
    • The macrophage and the apoptotic cell: An innate immune interaction viewed simplistically?
    • Gregory CD, Devitt A (2004) The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically? Immunology 113:1-14.
    • (2004) Immunology , vol.113 , pp. 1-14
    • Gregory, C.D.1    Devitt, A.2
  • 17
    • 73549089256 scopus 로고    scopus 로고
    • Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions
    • Henderson AP, Barnett MH, Parratt JD, Prineas JW (2009) Multiple sclerosis: distribution of inflammatory cells in newly forming lesions. Ann Neurol 66:739-753.
    • (2009) Ann Neurol , vol.66 , pp. 739-753
    • Henderson, A.P.1    Barnett, M.H.2    Parratt, J.D.3    Prineas, J.W.4
  • 18
    • 33845312662 scopus 로고    scopus 로고
    • Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis
    • Howell OW, Palser A, Polito A, Melrose S, Zonta B, Scheiermann C, Vora AJ, Brophy PJ, Reynolds R (2006) Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis. Brain 129:3173-3185.
    • (2006) Brain , vol.129 , pp. 3173-3185
    • Howell, O.W.1    Palser, A.2    Polito, A.3    Melrose, S.4    Zonta, B.5    Scheiermann, C.6    Vora, A.J.7    Brophy, P.J.8    Reynolds, R.9
  • 19
    • 33748138567 scopus 로고    scopus 로고
    • Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes
    • Ip CW, Kroner A, Bendszus M, Leder C, Kobsar I, Fischer S, Wiendl H, Nave KA, Martini R (2006) Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. J Neurosci 26:8206-8216.
    • (2006) J Neurosci , vol.26 , pp. 8206-8216
    • Ip, C.W.1    Kroner, A.2    Bendszus, M.3    Leder, C.4    Kobsar, I.5    Fischer, S.6    Wiendl, H.7    Nave, K.A.8    Martini, R.9
  • 21
    • 33749525328 scopus 로고    scopus 로고
    • Innate response to focal necrotic injury inside the blood-brain barrier
    • Kim JV, Dustin ML (2006) Innate response to focal necrotic injury inside the blood-brain barrier. J Immunol 177:5269-5277.
    • (2006) J Immunol , vol.177 , pp. 5269-5277
    • Kim, J.V.1    Dustin, M.L.2
  • 22
    • 0036788406 scopus 로고    scopus 로고
    • Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
    • Kuhlmann T, Lingfeld G, Bitsch A, Schuchardt J, Brück W (2002) Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 125:2202-2212.
    • (2002) Brain , vol.125 , pp. 2202-2212
    • Kuhlmann, T.1    Lingfeld, G.2    Bitsch, A.3    Schuchardt, J.4    Brück, W.5
  • 23
    • 0024074053 scopus 로고
    • Unwrapping the genes of myelin
    • Lemke G (1988) Unwrapping the genes of myelin. Neuron 1:535-543.
    • (1988) Neuron , vol.1 , pp. 535-543
    • Lemke, G.1
  • 26
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis
    • Lucchinetti CF, Brück W, Rodriguez M, Lassmann H (1996) Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis. Brain Pathol 6:259-274.
    • (1996) Brain Pathol , vol.6 , pp. 259-274
    • Lucchinetti, C.F.1    Brück, W.2    Rodriguez, M.3    Lassmann, H.4
  • 27
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H (2000) Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 47:707-717.
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Brück, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 28
    • 35649018602 scopus 로고    scopus 로고
    • Lesion genesis in a subset of patients with multiple sclerosis: A role for innate immunity?
    • Marik C, Felts PA, Bauer J, Lassmann H, Smith KJ (2007) Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity? Brain 130:2800-2815.
    • (2007) Brain , vol.130 , pp. 2800-2815
    • Marik, C.1    Felts, P.A.2    Bauer, J.3    Lassmann, H.4    Smith, K.J.5
  • 29
    • 77956394596 scopus 로고    scopus 로고
    • Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    • Merson TD, Binder MD, Kilpatrick TJ (2010) Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS. Neuromolecular Med 12:99-132.
    • (2010) Neuromolecular Med , vol.12 , pp. 99-132
    • Merson, T.D.1    Binder, M.D.2    Kilpatrick, T.J.3
  • 30
    • 78149433845 scopus 로고    scopus 로고
    • Myelination and support of axonal integrity by glia
    • Nave KA (2010) Myelination and support of axonal integrity by glia. Nature 468:244-252.
    • (2010) Nature , vol.468 , pp. 244-252
    • Nave, K.A.1
  • 32
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314-1318.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 33
    • 66049088725 scopus 로고    scopus 로고
    • Spatiotemporal ablation of myelinating glia-specific neurofascin (Nfasc NF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains
    • Pillai AM, Thaxton C, Pribisko AL, Cheng JG, Dupree JL, BhatMA (2009) Spatiotemporal ablation of myelinating glia-specific neurofascin (Nfasc NF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains. J Neurosci Res 87:1773-1793.
    • (2009) J Neurosci Res , vol.87 , pp. 1773-1793
    • Pillai, A.M.1    Thaxton, C.2    Pribisko, A.L.3    Cheng, J.G.4    Dupree, J.L.5    Bhat, M.A.6
  • 34
  • 35
    • 0345690096 scopus 로고    scopus 로고
    • The local differentiation of myelinated axons at nodes of Ranvier
    • Poliak S, Peles E (2003) The local differentiation of myelinated axons at nodes of Ranvier. Nat Rev Neurosci 4:968-980.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 968-980
    • Poliak, S.1    Peles, E.2
  • 39
    • 25144469422 scopus 로고    scopus 로고
    • Mechanisms of axon ensheathment and myelin growth
    • Sherman DL, Brophy PJ (2005) Mechanisms of axon ensheathment and myelin growth. Nat Rev Neurosci 6:683-690.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 683-690
    • Sherman, D.L.1    Brophy, P.J.2
  • 40
    • 27944436033 scopus 로고    scopus 로고
    • Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: Implications for multiple system atrophy
    • Shults CW, Rockenstein E, Crews L, Adame A, Mante M, Larrea G, Hashimoto M, Song D, Iwatsubo T, Tsuboi K, Masliah E (2005) Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. J Neurosci 25:10689-10699.
    • (2005) J Neurosci , vol.25 , pp. 10689-10699
    • Shults, C.W.1    Rockenstein, E.2    Crews, L.3    Adame, A.4    Mante, M.5    Larrea, G.6    Hashimoto, M.7    Song, D.8    Iwatsubo, T.9    Tsuboi, K.10    Masliah, E.11
  • 42
    • 0035101188 scopus 로고    scopus 로고
    • Dynamics of microglial activation: A confocal time-lapse analysis in hippocampal slices
    • Stence N, Waite M, Dailey ME (2001) Dynamics of microglial activation: a confocal time-lapse analysis in hippocampal slices. Glia 33:256-266.
    • (2001) Glia , vol.33 , pp. 256-266
    • Stence, N.1    Waite, M.2    Dailey, M.E.3
  • 45
    • 27744464859 scopus 로고    scopus 로고
    • The microglial "activation" continuum: From innate to adaptive responses
    • Town T, Nikolic V, Tan J (2005) The microglial "activation" continuum: from innate to adaptive responses. J Neuroinflammation 2:24.
    • (2005) J Neuroinflammation , vol.2 , pp. 24
    • Town, T.1    Nikolic, V.2    Tan, J.3
  • 46
    • 77957658807 scopus 로고    scopus 로고
    • A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination
    • Traka M, Arasi K, Avila RL, Podojil JR, Christakos A, Miller SD, Soliven B, Popko B (2010) A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination. Brain 133:3017-3029.
    • (2010) Brain , vol.133 , pp. 3017-3029
    • Traka, M.1    Arasi, K.2    Avila, R.L.3    Podojil, J.R.4    Christakos, A.5    Miller, S.D.6    Soliven, B.7    Popko, B.8
  • 48
    • 0032796747 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis: Relationship to neurologic disability
    • Trapp BD, Ransohoff R, Rudick R (1999) Axonal pathology in multiple sclerosis: relationship to neurologic disability. Curr Opin Neurol 12:295-302.
    • (1999) Curr Opin Neurol , vol.12 , pp. 295-302
    • Trapp, B.D.1    Ransohoff, R.2    Rudick, R.3
  • 49
    • 7344229312 scopus 로고    scopus 로고
    • Ion channel redistribution and function during development of the myelinated axon
    • Vabnick I, Shrager P (1998) Ion channel redistribution and function during development of the myelinated axon. J Neurobiol 37:80-96.
    • (1998) J Neurobiol , vol.37 , pp. 80-96
    • Vabnick, I.1    Shrager, P.2
  • 50
    • 5344228374 scopus 로고    scopus 로고
    • Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease
    • Weiner HL (2004) Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease. Arch Neurol 61:1613-1615.
    • (2004) Arch Neurol , vol.61 , pp. 1613-1615
    • Weiner, H.L.1
  • 51
    • 0037481891 scopus 로고    scopus 로고
    • Changes in the expression and localization of the paranodal protein Caspr on axons in chronic multiple sclerosis
    • Wolswijk G, Balesar R (2003) Changes in the expression and localization of the paranodal protein Caspr on axons in chronic multiple sclerosis. Brain 126:1638-1649.
    • (2003) Brain , vol.126 , pp. 1638-1649
    • Wolswijk, G.1    Balesar, R.2
  • 52
    • 0031973488 scopus 로고    scopus 로고
    • A minimal human MBP promoter-lacZ transgene is appropriately regulated in developing brain and after optic enucleation, but not in shiverer mutant mice
    • Wrabetz L, Taveggia C, Feltri ML, Quattrini A, Awatramani R, Scherer SS, Messing A, Kamholz J (1998) A minimal human MBP promoter-lacZ transgene is appropriately regulated in developing brain and after optic enucleation, but not in shiverer mutant mice. J Neurobiol 34:10-26.
    • (1998) J Neurobiol , vol.34 , pp. 10-26
    • Wrabetz, L.1    Taveggia, C.2    Feltri, M.L.3    Quattrini, A.4    Awatramani, R.5    Scherer, S.S.6    Messing, A.7    Kamholz, J.8
  • 53
    • 46249114300 scopus 로고    scopus 로고
    • Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system
    • Zonta B, Tait S, Melrose S, Anderson H, Harroch S, Higginson J, Sherman DL, Brophy PJ (2008) Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system. J Cell Biol 181:1169-1177.
    • (2008) J Cell Biol , vol.181 , pp. 1169-1177
    • Zonta, B.1    Tait, S.2    Melrose, S.3    Anderson, H.4    Harroch, S.5    Higginson, J.6    Sherman, D.L.7    Brophy, P.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.