-
1
-
-
0035135929
-
Small GTP-binding proteins
-
Takai, Y., Sasaki, T. & Matozaki, T. Small GTP-binding proteins. Physiol. Rev. 81, 153-208 (2001).
-
(2001)
Physiol. Rev.
, vol.81
, pp. 153-208
-
-
Takai, Y.1
Sasaki, T.2
Matozaki, T.3
-
2
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
Heasman, S. J. & Ridley, A. J. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat. Rev. Mol. Cell Biol. 9, 690-701 (2008).
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
3
-
-
77949541746
-
Proteinuria an enzymatic disease of the podocyte?
-
Mundel, P. & Reiser, J. Proteinuria: An enzymatic disease of the podocyte? Kidney Int. 77, 571-580 (2010).
-
(2010)
Kidney Int.
, vol.77
, pp. 571-580
-
-
Mundel, P.1
Reiser, J.2
-
4
-
-
84455169599
-
The podocyte cytoskeleton-key to a functioning glomerulus in health and disease
-
Welsh, G. I. & Saleem, M. A. The podocyte cytoskeleton - key to a functioning glomerulus in health and disease. Nat. Rev. Nephrol. 8, 14-21 (2012).
-
(2012)
Nat. Rev. Nephrol.
, vol.8
, pp. 14-21
-
-
Welsh, G.I.1
Saleem, M.A.2
-
5
-
-
33645747309
-
The Rac and Rho hall of fame: A decade of hypertrophic signaling hits
-
Brown, J. H., Del Re, D. P. & Sussman, M. A. The Rac and Rho hall of fame: A decade of hypertrophic signaling hits. Circ. Res. 98, 730-742 (2006).
-
(2006)
Circ. Res.
, vol.98
, pp. 730-742
-
-
Brown, J.H.1
Del Re, D.P.2
Sussman, M.A.3
-
6
-
-
43049161321
-
Small GTP-binding proteins and their regulators in cardiac hypertrophy
-
Lezoualc'h, F., Métrich, M., Hmitou, I., Duquesnes, N. & Morel, E. Small GTP-binding proteins and their regulators in cardiac hypertrophy. J. Mol. Cell. Cardiol. 44, 623-632 (2008).
-
(2008)
J. Mol. Cell. Cardiol.
, vol.44
, pp. 623-632
-
-
Lezoualc'h, F.1
Métrich, M.2
Hmitou, I.3
Duquesnes, N.4
Morel, E.5
-
7
-
-
77951879058
-
Aldosterone: Effects on the kidney and cardiovascular system
-
Briet, M. & Schiffrin, E. L. Aldosterone: Effects on the kidney and cardiovascular system. Nat. Rev. Nephrol. 6, 261-273 (2010).
-
(2010)
Nat. Rev. Nephrol.
, vol.6
, pp. 261-273
-
-
Briet, M.1
Schiffrin, E.L.2
-
8
-
-
79955622277
-
Mineralocorticoid receptor activation and blockade: An emerging paradigm in chronic kidney disease
-
Bertocchio, J. P., Warnock, D. G. & Jaisser, F. Mineralocorticoid receptor activation and blockade: An emerging paradigm in chronic kidney disease. Kidney Int. 79, 1051-1060 (2011).
-
(2011)
Kidney Int.
, vol.79
, pp. 1051-1060
-
-
Bertocchio, J.P.1
Warnock, D.G.2
Jaisser, F.3
-
9
-
-
1842688311
-
Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension
-
Williams, G. H. et al. Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension. Am. J. Cardiol. 93, 990-996 (2004).
-
(2004)
Am. J. Cardiol.
, vol.93
, pp. 990-996
-
-
Williams, G.H.1
-
11
-
-
33744981628
-
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker
-
Nagase, M. et al. Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. Hypertension 47, 1084-1093 (2006).
-
(2006)
Hypertension
, vol.47
, pp. 1084-1093
-
-
Nagase, M.1
-
12
-
-
57349168398
-
Modification of mineralocorticoid receptor function by Rac1 GTPase: Implication in proteinuric kidney disease
-
Shibata, S. et al. Modification of mineralocorticoid receptor function by Rac1 GTPase: Implication in proteinuric kidney disease. Nat. Med. 14, 1370-1376 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 1370-1376
-
-
Shibata, S.1
-
13
-
-
84861832781
-
Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation
-
Kawarazaki, W. et al. Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation. J. Am. Soc. Nephrol. 23, 997-1007 (2012).
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 997-1007
-
-
Kawarazaki, W.1
-
14
-
-
79960972766
-
Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway
-
Shibata, S. et al. Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. J. Clin. Invest. 121, 3233-3243 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3233-3243
-
-
Shibata, S.1
-
15
-
-
84856113013
-
Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: Role of small GTPase Rac1
-
Nagase, M. et al. Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac1. Hypertension 59, 500-506 (2012).
-
(2012)
Hypertension
, vol.59
, pp. 500-506
-
-
Nagase, M.1
-
16
-
-
0033581944
-
Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
-
Jordan, P., Brazao, R., Boavida, M. G., Gespach, C. & Chastre, E. Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors. Oncogene 18, 6835-6839 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 6835-6839
-
-
Jordan, P.1
Brazao, R.2
Boavida, M.G.3
Gespach, C.4
Chastre, E.5
-
17
-
-
0032585635
-
Rac1 is required for the formation of three germ layers during gastrulation
-
Sugihara, K. et al. Rac1 is required for the formation of three germ layers during gastrulation. Oncogene 17, 3427-3433 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 3427-3433
-
-
Sugihara, K.1
-
18
-
-
13444252631
-
GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
-
Rossman, K. L., Der, C. J. & Sondek, J. GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
19
-
-
34249018367
-
GEFs and GAPs: Critical elements in the control of small G proteins
-
Bos, J. L., Rehmann, H. & Wittinghofer, A. GEFs and GAPs: Critical elements in the control of small G proteins. Cell 129, 865-877 (2007).
-
(2007)
Cell
, vol.129
, pp. 865-877
-
-
Bos, J.L.1
Rehmann, H.2
Wittinghofer, A.3
-
20
-
-
0037121966
-
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression
-
Tzima, E. et al. Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. EMBO J. 21, 6791-6800 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 6791-6800
-
-
Tzima, E.1
-
21
-
-
0035861968
-
Reactive oxygen species in mechanical stress-induced cardiac hypertrophy
-
Aikawa, R. et al. Reactive oxygen species in mechanical stress-induced cardiac hypertrophy. Biochem. Biophys. Res. Commun. 289, 901-907 (2001).
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.289
, pp. 901-907
-
-
Aikawa, R.1
-
22
-
-
21444443229
-
Tumor necrosis factor - A stimulation of Rac1 activity Role of isoprenylcysteine carboxylmethyltransferase
-
Papaharalambus, C. et al. Tumor necrosis factor-a stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase. J. Biol. Chem. 280, 18790-18796 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18790-18796
-
-
Papaharalambus, C.1
-
23
-
-
1542373753
-
Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor
-
Kurokawa, K., Itoh, R. E., Yoshizaki, H., Nakamura, Y. O. & Matsuda, M. Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. Mol. Biol. Cell 15, 1003-1010 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1003-1010
-
-
Kurokawa, K.1
Itoh, R.E.2
Yoshizaki, H.3
Nakamura, Y.O.4
Matsuda, M.5
-
24
-
-
0031844821
-
Activation of Rac and Cdc42 by integrins mediates cell spreading
-
Price, L. S., Leng, J., Schwartz, M. A. & Bokoch, G. M. Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol. Biol. Cell. 9, 1863-1871 (1998).
-
(1998)
Mol. Biol. Cell.
, vol.9
, pp. 1863-1871
-
-
Price, L.S.1
Leng, J.2
Schwartz, M.A.3
Bokoch, G.M.4
-
25
-
-
44249108994
-
Superoxide destabilization of ß-catenin augments apoptosis of high glucose stressed mesangial cells
-
Lin, C. L. et al. Superoxide destabilization of ß-catenin augments apoptosis of high glucose stressed mesangial cells. Endocrinology 149, 2934-2942 (2008).
-
(2008)
Endocrinology
, vol.149
, pp. 2934-2942
-
-
Lin, C.L.1
-
26
-
-
67649118398
-
Rac1 is required for cardiomyocyte apoptosis during hyperglycemia
-
Shen, E. et al. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes 58, 2386-2395 (2009).
-
(2009)
Diabetes
, vol.58
, pp. 2386-2395
-
-
Shen, E.1
-
27
-
-
21644461236
-
Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells
-
Yi, F., Zhang, A. Y., Janscha, J. L., Li, P. L. & Zou, A. P. Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. Kidney Int. 66, 1977-1987 (2004).
-
(2004)
Kidney Int.
, vol.66
, pp. 1977-1987
-
-
Yi, F.1
Zhang, A.Y.2
Janscha, J.L.3
Li, P.L.4
Zou, A.P.5
-
28
-
-
0344668554
-
Rac MEKK3 MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock
-
Uhlik, M. T. et al. Rac MEKK3 MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Nat. Cell Biol. 5, 1104-1110 (2003).
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 1104-1110
-
-
Uhlik, M.T.1
-
29
-
-
24944582139
-
Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts
-
Friis, M. B. et al. Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts. J. Physiol. 567, 427-443 (2005).
-
(2005)
J. Physiol.
, vol.567
, pp. 427-443
-
-
Friis, M.B.1
-
30
-
-
75149166127
-
Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb
-
Silva, G. B. & Garvin, J. L. Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb. Am. J. Physiol. Renal Physiol. 298, F421-F425 (2010).
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.298
-
-
Silva, G.B.1
Garvin, J.L.2
-
31
-
-
75449088045
-
GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback
-
Liu, R. & Juncos, L. A. GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298, R453-R458 (2010).
-
(2010)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.298
-
-
Liu, R.1
Juncos, L.A.2
-
32
-
-
0035933742
-
Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck
-
Schmitz, U. et al. Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck. J. Biol. Chem. 276, 22003-22010 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22003-22010
-
-
Schmitz, U.1
-
33
-
-
0035186999
-
Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
-
Takemoto, M. et al. Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J. Clin. Invest. 108, 1429-1437 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1429-1437
-
-
Takemoto, M.1
-
34
-
-
20744448925
-
Ga12/13-and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes
-
Nishida, M. et al. Ga12/13-and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. J. Biol. Chem. 280, 18434-18441 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18434-18441
-
-
Nishida, M.1
-
35
-
-
33846443625
-
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1
-
Shibata, S., Nagase, M., Yoshida, S., Kawachi, H. & Fujita, T. Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 49, 355-364 (2007).
-
(2007)
Hypertension
, vol.49
, pp. 355-364
-
-
Shibata, S.1
Nagase, M.2
Yoshida, S.3
Kawachi, H.4
Fujita, T.5
-
36
-
-
40849083771
-
Aldosterone induces superoxide generation via Rac1 activation in endothelial cells
-
Iwashima, F. et al. Aldosterone induces superoxide generation via Rac1 activation in endothelial cells. Endocrinology 149, 1009-1014 (2008).
-
(2008)
Endocrinology
, vol.149
, pp. 1009-1014
-
-
Iwashima, F.1
-
37
-
-
40849126604
-
Rho exchange factors in the cardiovascular system
-
Loirand, G., Scalbert, E., Bril, A. & Pacaud, P. Rho exchange factors in the cardiovascular system. Curr. Opin. Pharmacol. 8, 174-180 (2008).
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 174-180
-
-
Loirand, G.1
Scalbert, E.2
Bril, A.3
Pacaud, P.4
-
38
-
-
0026335622
-
Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2
-
Knaus, U. G., Heyworth, P. G., Evans, T., Curnutte, J. T. & Bokoch, G. M. Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2. Science 254, 1512-1515 (1991).
-
(1991)
Science
, vol.254
, pp. 1512-1515
-
-
Knaus, U.G.1
Heyworth, P.G.2
Evans, T.3
Curnutte, J.T.4
Bokoch, G.M.5
-
39
-
-
0025944684
-
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
-
Abo, A. et al. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Nature 353, 668-670 (1991).
-
(1991)
Nature
, vol.353
, pp. 668-670
-
-
Abo, A.1
-
40
-
-
0032080913
-
Protection from reoxygenation injury by inhibition of rac1
-
Kim, K. S. et al. Protection from reoxygenation injury by inhibition of rac1. J. Clin. Invest. 101, 1821-1826 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1821-1826
-
-
Kim, K.S.1
-
41
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth, J. D. NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 4, 181-189 (2004).
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
42
-
-
34247175312
-
GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
-
Bustelo, X. R., Sauzeau, V. & Berenjeno, I. M. GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo. Bioessays 29, 356-370 (2007).
-
(2007)
Bioessays
, vol.29
, pp. 356-370
-
-
Bustelo, X.R.1
Sauzeau, V.2
Berenjeno, I.M.3
-
43
-
-
84855183026
-
Focal segmental glomerulosclerosis
-
D'Agati, V. D., Kaskel, F. J. & Falk, R. J. Focal segmental glomerulosclerosis. N. Engl. J. Med. 365, 2398-2411 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2398-2411
-
-
D'Agati, V.D.1
Kaskel, F.J.2
Falk, R.J.3
-
44
-
-
84857243208
-
Cell biology and pathology of podocytes
-
Greka, A. & Mundel, P. Cell biology and pathology of podocytes. Annu. Rev. Physiol. 74, 299-323 (2012).
-
(2012)
Annu. Rev. Physiol.
, vol.74
, pp. 299-323
-
-
Greka, A.1
Mundel, P.2
-
45
-
-
56949105292
-
Mechanisms of angiotensin II signaling on cytoskeleton of podocytes
-
Hsu, H. H. et al. Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. J. Mol. Med. (Berl.) 86, 1379-1394 (2008).
-
(2008)
J. Mol. Med. (Berl.
, vol.86
, pp. 1379-1394
-
-
Hsu, H.H.1
-
46
-
-
2542455650
-
Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats
-
Hoffmann, S., Podlich, D., Hahnel, B., Kriz, W. & Gretz, N. Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats. J. Am. Soc. Nephrol. 15, 1475-1487 (2004).
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 1475-1487
-
-
Hoffmann, S.1
Podlich, D.2
Hahnel, B.3
Kriz, W.4
Gretz, N.5
-
47
-
-
78049524253
-
Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels
-
Tian, D. et al. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Sci. Signal. 3, ra77 (2010).
-
(2010)
Sci. Signal.
, vol.3
-
-
Tian, D.1
-
48
-
-
0036906177
-
UPAR: A versatile signalling orchestrator
-
Blasi, F. & Carmeliet, P. uPAR: A versatile signalling orchestrator. Nat. Rev. Mol. Cell Biol. 3, 932-943 (2002).
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 932-943
-
-
Blasi, F.1
Carmeliet, P.2
-
49
-
-
48749127608
-
Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice
-
Jiang, M. et al. Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice. J. Clin. Invest. 118, 2733-2746 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2733-2746
-
-
Jiang, M.1
-
50
-
-
38049032013
-
Modification of kidney barrier function by the urokinase receptor
-
Wei, C. et al. Modification of kidney barrier function by the urokinase receptor. Nat. Med. 14, 55-63 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 55-63
-
-
Wei, C.1
-
51
-
-
80053410497
-
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
-
Akilesh, S. et al. Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. J. Clin. Invest. 121, 4127-4137 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4127-4137
-
-
Akilesh, S.1
-
52
-
-
33746658154
-
FilGAP a Rho-and ROCK-regulated GAP for Rac binds filamin A to control actin remodeling
-
Ohta, Y., Hartwig, J. H. & Stossel, T. P. FilGAP, a Rho-and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat. Cell Biol. 8, 803-814 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 803-814
-
-
Ohta, Y.1
Hartwig, J.H.2
Stossel, T.P.3
-
53
-
-
43749116673
-
HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein
-
Lu, T. C. et al. HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein. J. Biol. Chem. 283, 8173-8182 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8173-8182
-
-
Lu, T.C.1
-
54
-
-
33751226584
-
Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice
-
Lu, H. et al. Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice. Circulation 114, 2271-2279 (2006).
-
(2006)
Circulation
, vol.114
, pp. 2271-2279
-
-
Lu, H.1
-
55
-
-
0141841614
-
Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment
-
Maack, C. et al. Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. Circulation 108, 1567-1574 (2003).
-
(2003)
Circulation
, vol.108
, pp. 1567-1574
-
-
Maack, C.1
-
56
-
-
34447521792
-
Role of Rac1 GTPase activation in atrial fibrillation
-
Adam, O. et al. Role of Rac1 GTPase activation in atrial fibrillation. J. Am. Coll. Cardiol. 50, 359-367 (2007).
-
(2007)
J. Am. Coll. Cardiol.
, vol.50
, pp. 359-367
-
-
Adam, O.1
-
57
-
-
33644667603
-
CAMP-binding protein Epac induces cardiomyocyte hypertrophy
-
Morel, E. et al. cAMP-binding protein Epac induces cardiomyocyte hypertrophy. Circ. Res. 97, 1296-1304 (2005).
-
(2005)
Circ. Res.
, vol.97
, pp. 1296-1304
-
-
Morel, E.1
-
58
-
-
0036322869
-
Isoprenoids as mediators of the biological effects of statins
-
Liao, J. K. Isoprenoids as mediators of the biological effects of statins. J. Clin. Invest. 110, 285-288 (2002).
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 285-288
-
-
Liao, J.K.1
-
59
-
-
0042733080
-
Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: Cytoskeletal regulation of ERK translocation
-
Kawamura, S., Miyamoto, S. & Brown, J. H. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: Cytoskeletal regulation of ERK translocation. J. Biol. Chem. 278, 31111-31117 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31111-31117
-
-
Kawamura, S.1
Miyamoto, S.2
Brown, J.H.3
-
60
-
-
0032167411
-
A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy
-
Pracyk, J. B. et al. A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy. J. Clin. Invest. 102, 929-937 (1998).
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 929-937
-
-
Pracyk, J.B.1
-
61
-
-
8844262660
-
Principles for modulation of the nuclear receptor superfamily
-
Gronemeyer, H., Gustafsson, J. A. & Laudet, V. Principles for modulation of the nuclear receptor superfamily. Nat. Rev. Drug Discov. 3, 950-964 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 950-964
-
-
Gronemeyer, H.1
Gustafsson, J.A.2
Laudet, V.3
-
62
-
-
0037488488
-
Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure
-
Qin, W. et al. Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure. Circ. Res. 93, 69-76 (2003).
-
(2003)
Circ. Res.
, vol.93
, pp. 69-76
-
-
Qin, W.1
-
63
-
-
20844459494
-
Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice
-
Garnier, A. et al. Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice. Circulation 110, 1819-1825 (2004).
-
(2004)
Circulation
, vol.110
, pp. 1819-1825
-
-
Garnier, A.1
-
64
-
-
20544464438
-
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias
-
Ouvrard-Pascaud, A. et al. Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. Circulation 111, 3025-3033 (2005).
-
(2005)
Circulation
, vol.111
, pp. 3025-3033
-
-
Ouvrard-Pascaud, A.1
-
65
-
-
0027081410
-
Mineralocorticoid excess, dietary sodium, and myocardial fibrosis
-
Brilla, C. G. & Weber, K. T. Mineralocorticoid excess, dietary sodium, and myocardial fibrosis. J. Lab. Clin. Med. 120, 893-901 (1992).
-
(1992)
J. Lab. Clin. Med.
, vol.120
, pp. 893-901
-
-
Brilla, C.G.1
Weber, K.T.2
-
66
-
-
79751529118
-
Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction
-
Fraccarollo, D. et al. Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction. Circulation 123, 400-408 (2011).
-
(2011)
Circulation
, vol.123
, pp. 400-408
-
-
Fraccarollo, D.1
-
67
-
-
79953224745
-
Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function
-
Lother, A. et al. Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. Hypertension 57, 746-754 (2011).
-
(2011)
Hypertension
, vol.57
, pp. 746-754
-
-
Lother, A.1
-
68
-
-
33845687252
-
High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction
-
Beygui, F. et al. High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction. Circulation 114, 2604-2610 (2006).
-
(2006)
Circulation
, vol.114
, pp. 2604-2610
-
-
Beygui, F.1
-
69
-
-
34247203651
-
Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure
-
Guder, G. et al. Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure. Circulation 115, 1754-1761 (2007).
-
(2007)
Circulation
, vol.115
, pp. 1754-1761
-
-
Guder, G.1
-
70
-
-
0033517302
-
The effect of spironolactone on morbidity and mortality in patients with severe heart failure Randomized Aldactone Evaluation Study Investigators
-
Pitt, B. et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N. Engl. J. Med. 341, 709-717 (1999).
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 709-717
-
-
Pitt, B.1
-
71
-
-
0037417252
-
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
-
Pitt, B. et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N. Engl. J. Med. 348, 1309-1321 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1309-1321
-
-
Pitt, B.1
-
72
-
-
78650399880
-
Eplerenone in patients with systolic heart failure and mild symptoms
-
Zannad, F. et al. Eplerenone in patients with systolic heart failure and mild symptoms. N. Engl. J. Med. 364, 11-21 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 11-21
-
-
Zannad, F.1
-
73
-
-
84864493727
-
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology Developed in collaboration with the Heart Failure Association (HFA) of the ESC
-
McMurray, J. J. et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur. Heart J. 33, 1787-1847 (2012).
-
(2012)
Eur. Heart J.
, vol.33
, pp. 1787-1847
-
-
McMurray, J.J.1
-
74
-
-
77955444052
-
Rationale And Design Of The 'Aldosterone Receptor Blockade in Diastolic Heart Failure' trial: A double-blind, randomized, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and diastolic function in patients with symptomatic diastolic heart failure (Aldo-DHF)
-
Edelmann, F. et al. Rationale and design of the 'Aldosterone Receptor Blockade in Diastolic Heart Failure' trial: A double-blind, randomized, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and diastolic function in patients with symptomatic diastolic heart failure (Aldo-DHF). Eur. J. Heart Fail. 12, 874-882 (2010).
-
(2010)
Eur. J. Heart Fail.
, vol.12
, pp. 874-882
-
-
Edelmann, F.1
-
75
-
-
82555168277
-
Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction
-
e910
-
Desai, A. S. et al. Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction. Am. Heart J. 162, 966-972 e910 (2011).
-
(2011)
Am. Heart J.
, vol.162
, pp. 966-972
-
-
Desai, A.S.1
-
76
-
-
84856100794
-
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
-
He, B. J. et al. Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. Nat. Med. 17, 1610-1618 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 1610-1618
-
-
He, B.J.1
-
77
-
-
70349257487
-
Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
-
Rickard, A. J. et al. Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure. Hypertension 54, 537-543 (2009).
-
(2009)
Hypertension
, vol.54
, pp. 537-543
-
-
Rickard, A.J.1
-
78
-
-
0033598349
-
Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIa
-
Togawa, A. et al. Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIa. Oncogene 18, 5373-5380 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 5373-5380
-
-
Togawa, A.1
-
79
-
-
0035793554
-
Rho GTPases as modulators of the estrogen receptor transcriptional response
-
Su, L. F., Knoblauch, R. & Garabedian, M. J. Rho GTPases as modulators of the estrogen receptor transcriptional response. J. Biol. Chem. 276, 3231-3237 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3231-3237
-
-
Su, L.F.1
Knoblauch, R.2
Garabedian, M.J.3
-
80
-
-
0142219882
-
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter
-
Cai, D. et al. AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter. Cancer Res. 63, 6802-6808 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 6802-6808
-
-
Cai, D.1
-
81
-
-
0037107380
-
P21-activated kinase-1 phosphorylates and transactivates estrogen receptor - A and promotes hyperplasia in mammary epithelium
-
Wang, R. A., Mazumdar, A., Vadlamudi, R. K. & Kumar, R. P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-a and promotes hyperplasia in mammary epithelium. EMBO J. 21, 5437-5447 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 5437-5447
-
-
Wang, R.A.1
Mazumdar, A.2
Vadlamudi, R.K.3
Kumar, R.4
-
82
-
-
40849113350
-
Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer
-
Lyons, L. S. et al. Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer. Mol. Endocrinol. 22, 597-608 (2008).
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 597-608
-
-
Lyons, L.S.1
-
83
-
-
33646929597
-
Rho family guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system
-
Kino, T. et al. Rho family guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system. J. Biol. Chem. 281, 9118-9126 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9118-9126
-
-
Kino, T.1
-
84
-
-
35848952953
-
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: Role of oxidative stress
-
Nagase, M., Matsui, H., Shibata, S., Gotoda, T. & Fujita, T. Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress. Hypertension 50, 877-883 (2007).
-
(2007)
Hypertension
, vol.50
, pp. 877-883
-
-
Nagase, M.1
Matsui, H.2
Shibata, S.3
Gotoda, T.4
Fujita, T.5
-
85
-
-
14644395574
-
Weight loss and the reninYangiotensinYaldosterone system
-
Engeli, S. et al. Weight loss and the reninYangiotensinYaldosterone system. Hypertension 45, 356-362 (2005).
-
(2005)
Hypertension
, vol.45
, pp. 356-362
-
-
Engeli, S.1
-
86
-
-
49849106703
-
Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder
-
Matsui, H. et al. Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder. Hypertension 52, 287-294 (2008).
-
(2008)
Hypertension
, vol.52
, pp. 287-294
-
-
Matsui, H.1
-
87
-
-
14644442283
-
Oxygen oxidative stress, hypoxia, and heart failure
-
Giordano, F. J. Oxygen, oxidative stress, hypoxia, and heart failure. J. Clin. Invest. 115, 500-508 (2005).
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 500-508
-
-
Giordano, F.J.1
-
88
-
-
2542486409
-
Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy
-
Matsui, Y. et al. Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy. Hypertension 43, 1195-1201 (2004).
-
(2004)
Hypertension
, vol.43
, pp. 1195-1201
-
-
Matsui, Y.1
-
89
-
-
0035090207
-
Mineralocorticoid receptor affects AP-1 and nuclear factor-?B activation in angiotensin II-induced cardiac injury
-
Fiebeler, A. et al. Mineralocorticoid receptor affects AP-1 and nuclear factor-?B activation in angiotensin II-induced cardiac injury. Hypertension 37, 787-793 (2001).
-
(2001)
Hypertension
, vol.37
, pp. 787-793
-
-
Fiebeler, A.1
-
90
-
-
0031000789
-
Specific nongenomic actions of steroid hormones
-
Wehling, M. Specific, nongenomic actions of steroid hormones. Annu. Rev. Physiol. 59, 365-393 (1997).
-
(1997)
Annu. Rev. Physiol.
, vol.59
, pp. 365-393
-
-
Wehling, M.1
-
91
-
-
0034733041
-
Stimulation of NF?B activity by multiple signaling pathways requires PAK1
-
Frost, J. A. et al. Stimulation of NF?B activity by multiple signaling pathways requires PAK1. J. Biol. Chem. 275, 19693-19699 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19693-19699
-
-
Frost, J.A.1
-
92
-
-
0034613161
-
Regulation of STAT3 by direct binding to the Rac1 GTPase
-
Simon, A R. et al. Regulation of STAT3 by direct binding to the Rac1 GTPase. Science 290, 144-147 (2000).
-
(2000)
Science
, vol.290
, pp. 144-147
-
-
Simon, A.R.1
-
93
-
-
33845686162
-
Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors
-
Kawashima, T. et al. Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors. J. Cell Biol. 175, 937-946 (2006).
-
(2006)
J. Cell Biol.
, vol.175
, pp. 937-946
-
-
Kawashima, T.1
-
94
-
-
41949105179
-
Rac1 activation controls nuclear localization of ß-catenin during canonical Wnt signaling
-
Wu, X. et al. Rac1 activation controls nuclear localization of ß-catenin during canonical Wnt signaling. Cell 133, 340-353 (2008).
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
-
95
-
-
76749092246
-
The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events
-
Galigniana, M. D., Erlejman, A. G., Monte, M., Gomez-Sanchez, C. & Piwien-Pilipuk, G. The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events. Mol. Cell. Biol. 30, 1285-1298 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1285-1298
-
-
Galigniana, M.D.1
Erlejman, A.G.2
Monte, M.3
Gomez-Sanchez, C.4
Piwien-Pilipuk, G.5
-
96
-
-
82555167019
-
FKBP51 and FKBP52 in signaling and disease
-
Storer, C. L., Dickey, C. A., Galigniana, M. D., Rein, T. & Cox, M. B. FKBP51 and FKBP52 in signaling and disease. Trends Endocrinol. Metab. 22, 481-490 (2011).
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 481-490
-
-
Storer, C.L.1
Dickey, C.A.2
Galigniana, M.D.3
Rein, T.4
Cox, M.B.5
-
97
-
-
77951231146
-
Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport
-
Kim, J. H. et al. Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport. J. Biol. Chem. 285, 9995-10004 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9995-10004
-
-
Kim, J.H.1
-
98
-
-
77957989342
-
Dose-and time-dependent glucocorticoid receptor signaling in podocytes
-
Guess, A. et al. Dose-and time-dependent glucocorticoid receptor signaling in podocytes. Am. J. Physiol. Renal Physiol. 299, F845-F853 (2010).
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Guess, A.1
-
99
-
-
0030040856
-
The Ras-related GTPase Rac1 binds tubulin
-
Best, A., Ahmed, S., Kozma, R. & Lim, L. The Ras-related GTPase Rac1 binds tubulin. J. Biol. Chem. 271, 3756-3762 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3756-3762
-
-
Best, A.1
Ahmed, S.2
Kozma, R.3
Lim, L.4
-
100
-
-
28144458158
-
Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy
-
Buscemi, N. et al. Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 289, H2325-H2333 (2005).
-
(2005)
Am. J. Physiol. Heart Circ. Physiol.
, vol.289
-
-
Buscemi, N.1
-
101
-
-
34250690433
-
Kinases and protein phosphorylation as regulators of steroid hormone action
-
Weigel, N. L. & Moore, N. L. Kinases and protein phosphorylation as regulators of steroid hormone action. Nucl. Recept. Signal. 5, e005 (2007).
-
(2007)
Nucl. Recept. Signal.
, vol.5
-
-
Weigel, N.L.1
Moore, N.L.2
-
102
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
McKenna, N. J. & O'Malley, B. W. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108, 465-474 (2002).
-
(2002)
Cell
, vol.108
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
103
-
-
0025697567
-
Regulation of progesterone receptor-mediated transcription by phosphorylation
-
Denner, L. A., Weigel, N. L., Maxwell, B. L., Schrader, W. T. & O'Malley, B. W. Regulation of progesterone receptor-mediated transcription by phosphorylation. Science 250, 1740-1743 (1990).
-
(1990)
Science
, vol.250
, pp. 1740-1743
-
-
Denner, L.A.1
Weigel, N.L.2
Maxwell, B.L.3
Schrader, W.T.4
O'Malley, B.W.5
-
104
-
-
0032921063
-
Modulation of human mineralocorticoid receptor function by protein kinase A
-
Massaad, C., Houard, N., Lombes, M. & Barouki, R. Modulation of human mineralocorticoid receptor function by protein kinase A. Mol. Endocrinol. 13, 57-65 (1999).
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 57-65
-
-
Massaad, C.1
Houard, N.2
Lombes, M.3
Barouki, R.4
-
105
-
-
1942442455
-
Early nongenomic events in aldosterone action in renal collecting duct cells: PKCa activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response
-
Le Moellic, C. et al. Early nongenomic events in aldosterone action in renal collecting duct cells: PKCa activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response. J. Am. Soc. Nephrol. 15, 1145-1160 (2004).
-
(2004)
J. Am. Soc. Nephrol.
, vol.15
, pp. 1145-1160
-
-
Le Moellic, C.1
-
106
-
-
33847304631
-
Coactivation of the N-terminal transactivation of mineralocorticoid receptor by Ubc9
-
Yokota, K. et al. Coactivation of the N-terminal transactivation of mineralocorticoid receptor by Ubc9. J. Biol. Chem. 282, 1998-2010 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 1998-2010
-
-
Yokota, K.1
-
107
-
-
77950871339
-
NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor
-
Murai-Takeda, A. et al. NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor. J. Biol. Chem. 285, 8084-8093 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8084-8093
-
-
Murai-Takeda, A.1
-
108
-
-
38749154752
-
The mineralocorticoid receptor: Insights into its molecular and (patho)physiological biology
-
Viengchareun, S. et al. The mineralocorticoid receptor: Insights into its molecular and (patho)physiological biology. Nucl. Recept. Signal. 5, e012 (2007).
-
(2007)
Nucl. Recept. Signal.
, vol.5
-
-
Viengchareun, S.1
-
109
-
-
84856315210
-
Interactions of the mineralocorticoid receptor-within and without
-
Yang, J. & Fuller, P. J. Interactions of the mineralocorticoid receptor-within and without. Mol. Cell. Endocrinol. 350, 196-205 (2012).
-
(2012)
Mol. Cell. Endocrinol.
, vol.350
, pp. 196-205
-
-
Yang, J.1
Fuller, P.J.2
-
110
-
-
33646495978
-
Actin in transcription and transcription regulation
-
Miralles, F. & Visa, N. Actin in transcription and transcription regulation. Curr. Opin. Cell. Biol. 18, 261-266 (2006).
-
(2006)
Curr. Opin. Cell. Biol.
, vol.18
, pp. 261-266
-
-
Miralles, F.1
Visa, N.2
-
111
-
-
77953184636
-
Rationale and design of the Eplerenone Combination Versus Conventional Agents to Lower Blood Pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial: A double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric effects of an aldosterone blocker in hypertensive patients with albuminuria
-
Ando, K. et al. Rationale and design of the Eplerenone Combination Versus Conventional Agents to Lower Blood Pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial: A double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric effects of an aldosterone blocker in hypertensive patients with albuminuria. Hypertens. Res. 33, 616-621 (2010).
-
(2010)
Hypertens. Res.
, vol.33
, pp. 616-621
-
-
Ando, K.1
|