Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIα

Oncogene

Volumn 18, Issue 39, 1999, Pages 5373-5380

  Togawa, Atsushi ^a,e   Miyoshi, Jun ^a   Ishizaki, Hiroyoshi ^a   Tanaka, Miki ^a   Takakura, Ayumi ^a   Nishioka, Hidco ^a   Yoshida, Hisahiro ^b   Doi, Toshio ^c   Mizoguchi, Akira ^b   Matsuura, Nariaki ^d   Niho, Yoshiyuki ^e   Nishimune, Yoshitake ^f   Nishikawa, Shin Ichi ^b   Takai, Yoshimi ^a,g  

^a JCR Pharmaceuticals Co Ltd   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

^f OSAKA UNIVERSITY   (Japan)

^g OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Gene targeting; Infertility; Nephrotic syndrome; Rho; Rho GDI ; Small G protein

Indexed keywords

ACTIN; CYTOSKELETON PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; RHO FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUSE OF DEATH; CELL FUNCTION; CYTOSOL; DEVELOPMENTAL DISORDER; FEMALE; GENE DISRUPTION; GENETIC RECOMBINATION; GENITAL SYSTEM DISEASE; HISTOLOGY; KIDNEY DISEASE; KIDNEY FAILURE; MALE; MALE INFERTILITY; MOUSE; NEPHROTIC SYNDROME; NIDATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FAMILY; PROTEINURIA; SEMINIFEROUS TUBULE; SPERMATOGENESIS; TESTIS;

AGE FACTORS; ANIMALS; EPITHELIAL CELLS; FEMALE; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; INFERTILITY, MALE; KIDNEY FAILURE; KIDNEY TUBULES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEPHROTIC SYNDROME; TESTIS;

EID: 0033598349     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202921     Document Type: Article

References (42)

1. Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Aelst LV, Cerione RA and Lim B. (1997). Proc. Natl Acad. Sci. USA, 94, 4279-4284.
2. Bradford MM. (1976). Anal. Biochem., 72, 248-254.
3. Bradley A, (1987). In: Teratocarcinomas and Embryonic Stem Cells: A Practical Approach, Robertson EJ. (ed.). IRL Press: London, pp. 113-151.
4. Braga VMM, Machesky LM, Hall A and Hotchin NA. (1997). J. Cell Biol., 137, 1421-1431.
5. Chuang TH, Bohl BP and Bokoch GM. (1993). J. Biol. Chem., 268, 26206-26211.
6. Frisch SM and Francis H. (1994). J. Cell Biol., 124, 619-626.
7. Fukumoto Y, Kaibuchi K, Hori Y, Fujioka H, Araki S, Ueda T, Kikuchi A and Takai Y. (1990). Oncogene, 5, 1321-1328.
8. Hall A. (1994). Ann. Rev. Cell Biol., 10, 31-54.
9. Hall A. (1998). Science, 279, 509-514.
10. Hill CS, Wynne J and Treisman R. (1995). Cell, 81, 1159-1170.
11. Hiraoka K, Kaibuchi K, Ando S, Musha T, Takaishi K, Mizuno T, Asada M, Menard KL, Tomhave E, Didsbury J, Snyderman R and Takai Y. (1992). Biochem. Biophys. Res. Commun., 182, 921-930.
12. Hogan B, Beddington R, Costantini F and Lacy E. (1994). Manipulating the Mouse Embryo: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press: New York, pp. 296-298.
13. Imamura H, Takaishi K, Nakano K, Kodama A, Oishi H, Shiozaki H, Monden M, Sasuki T and Takai Y. (1998). Mol. Biol. Cell, 9, 2561-2575.
14. Isomura M, Kikuchi A, Ohga N and Takai Y. (1991). Oncogene, 6, 119-124.
15. Khosravi-Far R, Solski PA, Clark GJ, Kinch MS and Der CJ. (1995). Mol. Cell. Biol., 15, 6443-6453.
16. Koera K, Nakamura K, Nakao K, Miyoshi J, Toyoshima K, Hatta T, Otani H, Aiba A and Katsuki M. (1997). Oncogene, 15, 1151-1159.
17. Komuro R, Sasaki T, Takaishi K, Orita S and Takai Y. (1996). Genes Cells, 1, 943-951.
18. Kotani H, Takaishi K, Sasaki T and Takai Y. (1997). Oncogene, 14, 1705-1713.
19. Laemmli UK. (1970). Nature, 227, 680-685.
20. Lamarche N, Tapon N, Stowers L, Burbelo PD, Aspenstrom P, Bridges T, Chant J and Hall A. (1996). Cell, 87, 519-529.
21. Lamaze C, Chuang T-H, Terlecky LJ, Bokoch GM and Schmid SL. (1996). Nature, 382, 177-179.
22. Leilas J-M, Adra CN, Wulf CM, Guillemot J-C, Khagad M, Caput D and Lim B. (1993). Proc. Natl. Acad. Sci. USA, 90, 1479-1483.
23. Leonard D, Hart M, Platko J, Eva A, Henzel W, Evans T and Cerionc RA. (1992). J. Biol. Chem., 267, 22860-22868.
24. Mandai K, Nakanashi H, Satoh A, Obaishi H, Wada M, Nishioka H, Itoh M, Mizoguchi A, Aoki T, Fujimoto T, Matsuda Y, Tsukita S and Takai T. (1997). J. Cell Biol., 139, 517-528.
25. Mariol P, O'Sullivan AJ, Brown AM and Tatham PE. (1996). EMBO J., 15, 6476-6482.
26. Minden A, Lin A, Claret FX, Abo A and Karin M. (1995). Cell, 81, 1147-1157.
27. Miura Y, Kikuchi A, Musha T, Kuroda S, Yaku H, Sasaki T and Takai Y. (1993). J. Biol. Chem., 268, 510-515.
28. Nobes CD and Hall A. (1995). Cell, 81, 53-62.
29. Olson MF, Ashworth A and Hall A. (1995). Science, 269, 1270-1272.
30. Platko JV, Leonard DA, Adra CN, Shaw RJ, Cerione RA and Lim B. (1995). Proc. Natl. Acad. Sci. USA, 92, 2974-2978.
31. Price LS, Norman JC, Ridley AJ and Koffer A. (1995). Curr. Biol., 5, 68-73.
32. Riethmacher D, Brinkman V and Birchmeier C. (1995). Proc. Natl. Acad. Sci. USA, 92, 855-859.
33. Qiu RG, Chen J, Kirn D, McCormick F and Symons M. (1995). Nature. 374, 457-459.
34. Robertson EJ. (1987). In: Teratocarcinomas and Embryonic Stem Cells: A Practical Approach, Robertson EJ. (ed.). IRL Press: London, pp. 71-112.
35. Scherle P, Behrens T and Staudt LM. (1993). Proc. Natl. Acad. Sci. USA, 90, 7568-7572.
36. Takai Y, Sasaki T, Tanaka K and Nakanishi H. (1995). Trends Biochem. Sci., 20, 227-231.
37. Takai Y, Sasaki T, Shirataki H and Nakanishi H. (1996). Genes Cells, 1, 615-632.
38. Takaishi K, Kikuchi A, Kuroda S, Kotani K, Sasaki T and Takai Y. (1993). Mol. Cell. Biol. 13, 72-79.
39. Takaishi K, Sasaki T, Kato M, Yamochi W, Kuroda S, Nakamura T, Takeichi M and Takai Y. (1994). Oncogene, 9, 273-279.
40. Takaishi K, Sasaki T, Kotani H, Nishioka H and Takai Y. (1997). J. Cell Biol., 139, 1047-1059.
41. Ueda T, Kikuchi A, Ohga N, Yamamoto J and Takai Y. (1990). J. Biol. Chem., 265, 9373-9380.
42. Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck M-F, Tavitian A and Olofsson B. (1996). J. Biol. Chem., 271, 30366-30374.