SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds

Cell Death and Disease

Volumn 2, Issue 4, 2011, Pages

  Cheung, H H ^a   Jean, M St ^a   Beug, S T ^a   Lejmi Mrad, R ^a,b   La Casse, E ^a   Baird, S D ^a   Stojdl, D F ^a,b   Screaton, R A ^a,b   Korneluk, R G ^a,b  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

C FLIP; Cancer; Kinomic screen; Smac mimetic compound; TNFa

Indexed keywords

AEG 40730; ANTINEOPLASTIC AGENT; CASPASE 8; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; MESSENGER RNA; NUCLEAR FACTOR KAPPA B INDUCING KINASE; PEPTIDOMIMETIC AGENT; SM 164; SMAC MIMETIC COMPOUND; SMALL INTERFERING RNA; SUPPRESSOR OF MORPHOGENESIS IN GENITALIA 1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; NF KAPPA B KINASE; NF-KAPPA B KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE; SMG1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; GENE REPRESSION; GENETIC SCREENING; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; NEOPLASM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79959967783     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.25     Document Type: Article

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