Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype

Oncogene

Volumn 24, Issue 9, 2005, Pages 1580-1588

  Neben, Kai ^a   Schnittger, Susanne ^b   Brors, Benedikt ^a   Tews, Björn ^a   Kokocinski, Felix ^a   Haferlach, Torsten ^b   Müller, Jasmin ^a   Hahn, Meinhard ^a   Hiddemann, Wolfgang ^b   Eils, Roland ^a   Lichter, Peter ^a   Schoch, Claudia ^b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Acute myeloid leukemia; FLT3 activating mutations; Gene expression profiling; Normal karyotype; NRAS activating mutations

Indexed keywords

COMPLEMENTARY DNA; PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR; CD135 ANTIGEN; FLT3 PROTEIN, HUMAN; ONCOPROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CELL CYCLE; DNA MICROARRAY; FLT3 ACTIVATING MUTATION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; KARYOTYPE; LEUKEMIA; MAJOR CLINICAL STUDY; NRAS ACTIVATING MUTATION; NUCLEOTIDE SEQUENCE; ONCOGENE N RAS; POINT MUTATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; GENE EXPRESSION REGULATION; GENETICS; KARYOTYPING; MUTATION; ONCOGENE RAS; POLYMERASE CHAIN REACTION; PROBABILITY;

FMS-LIKE TYROSINE KINASE 3; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; KARYOTYPING; LEUKEMIA, MYELOCYTIC, ACUTE; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; PROBABILITY; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 20144381877     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208344     Document Type: Article

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