-
1
-
-
84859950150
-
Inborn errors of human JAKs and STATs
-
Casanova J.L., et al. Inborn errors of human JAKs and STATs. Immunity 2012, 36:515-528.
-
(2012)
Immunity
, vol.36
, pp. 515-528
-
-
Casanova, J.L.1
-
2
-
-
84867882468
-
Human B cell defects in perspective
-
Cunningham-Rundles C. Human B cell defects in perspective. Immunol. Res. 2012, 54:227-232.
-
(2012)
Immunol. Res.
, vol.54
, pp. 227-232
-
-
Cunningham-Rundles, C.1
-
3
-
-
84856230192
-
New frontiers of primary antibody deficiencies
-
van der Burg M., et al. New frontiers of primary antibody deficiencies. Cell. Mol. Life Sci. 2012, 69:59-73.
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, pp. 59-73
-
-
van der Burg, M.1
-
4
-
-
77956226592
-
Understanding human genetic variation in the era of high-throughput sequencing
-
Knight J.C. Understanding human genetic variation in the era of high-throughput sequencing. EMBO Rep. 2010, 11:650-652.
-
(2010)
EMBO Rep.
, vol.11
, pp. 650-652
-
-
Knight, J.C.1
-
5
-
-
80054746492
-
Exome sequencing as a tool for Mendelian disease gene discovery
-
Bamshad M.J., et al. Exome sequencing as a tool for Mendelian disease gene discovery. Nat. Rev. Genet. 2011, 12:745-755.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 745-755
-
-
Bamshad, M.J.1
-
6
-
-
80054928002
-
Genomics and the multifactorial nature of human autoimmune disease
-
Cho J.H., Gregersen P.K. Genomics and the multifactorial nature of human autoimmune disease. N. Engl. J. Med. 2011, 365:1612-1623.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1612-1623
-
-
Cho, J.H.1
Gregersen, P.K.2
-
7
-
-
80052325959
-
Pervasive sharing of genetic effects in autoimmune disease
-
Cotsapas C., et al. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet. 2011, 7:e1002254.
-
(2011)
PLoS Genet.
, vol.7
-
-
Cotsapas, C.1
-
8
-
-
79952902493
-
From expression QTLs to personalized transcriptomics
-
Montgomery S.B., Dermitzakis E.T. From expression QTLs to personalized transcriptomics. Nat. Rev. Genet. 2011, 12:277-282.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 277-282
-
-
Montgomery, S.B.1
Dermitzakis, E.T.2
-
9
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS
-
Nicolae D.L., et al. Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet. 2010, 6:e1000888.
-
(2010)
PLoS Genet.
, vol.6
-
-
Nicolae, D.L.1
-
10
-
-
79151484424
-
The study of eQTL variations by RNA-seq: from SNPs to phenotypes
-
Majewski J., Pastinen T. The study of eQTL variations by RNA-seq: from SNPs to phenotypes. Trends Genet. 2010, 27:72-79.
-
(2010)
Trends Genet.
, vol.27
, pp. 72-79
-
-
Majewski, J.1
Pastinen, T.2
-
11
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Durbin R.M., et al. A map of human genome variation from population-scale sequencing. Nature 2010, 467:1061-1073.
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Durbin, R.M.1
-
12
-
-
84858842234
-
Resolving the variable genome and epigenome in human disease
-
Knight J.C. Resolving the variable genome and epigenome in human disease. J. Intern. Med. 2012, 271:379-391.
-
(2012)
J. Intern. Med.
, vol.271
, pp. 379-391
-
-
Knight, J.C.1
-
13
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Consortium E.P. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Consortium, E.P.1
-
14
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
Rakyan V.K., et al. Epigenome-wide association studies for common human diseases. Nat. Rev. Genet. 2011, 12:529-541.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 529-541
-
-
Rakyan, V.K.1
-
15
-
-
78149399654
-
Epigenetic regulation of the immune system in health and disease
-
Fernandez-Morera J.L., et al. Epigenetic regulation of the immune system in health and disease. Tissue Antigens 2010, 76:431-439.
-
(2010)
Tissue Antigens
, vol.76
, pp. 431-439
-
-
Fernandez-Morera, J.L.1
-
17
-
-
84865308028
-
Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes
-
Boisson-Dupuis S., et al. Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes. Curr. Opin. Immunol. 2012, 24:364-378.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 364-378
-
-
Boisson-Dupuis, S.1
-
18
-
-
0022430251
-
A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes
-
de Preval C., et al. A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes. Nature 1985, 318:291-293.
-
(1985)
Nature
, vol.318
, pp. 291-293
-
-
de Preval, C.1
-
19
-
-
0035064073
-
The bare lymphocyte syndrome and the regulation of MHC expression
-
Reith W., Mach B. The bare lymphocyte syndrome and the regulation of MHC expression. Annu. Rev. Immunol. 2001, 19:331-373.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 331-373
-
-
Reith, W.1
Mach, B.2
-
20
-
-
79954463242
-
Control of central and peripheral tolerance by Aire
-
Metzger T.C., Anderson M.S. Control of central and peripheral tolerance by Aire. Immunol. Rev. 2011, 241:89-103.
-
(2011)
Immunol. Rev.
, vol.241
, pp. 89-103
-
-
Metzger, T.C.1
Anderson, M.S.2
-
21
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett C.L., et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 2001, 27:20-21.
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
22
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin R.S., et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 2001, 27:18-20.
-
(2001)
Nat. Genet.
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
-
23
-
-
79961154447
-
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis
-
Liu L., et al. Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis. J. Exp. Med. 2011, 208:1635-1648.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1635-1648
-
-
Liu, L.1
-
24
-
-
73949125253
-
Novel ORC4L gene mutation in B-cell lymphoproliferative disorders
-
Radojkovic M., et al. Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. Am. J. Med. Sci. 2009, 338:527-529.
-
(2009)
Am. J. Med. Sci.
, vol.338
, pp. 527-529
-
-
Radojkovic, M.1
-
25
-
-
84857728623
-
Classification of primary immunodeficiency diseases by the International Union of Immunological Societies (IUIS) Expert Committee on Primary Immunodeficiency 2011
-
Chapel H. Classification of primary immunodeficiency diseases by the International Union of Immunological Societies (IUIS) Expert Committee on Primary Immunodeficiency 2011. Clin. Exp. Immunol. 2012, 168:58-59.
-
(2012)
Clin. Exp. Immunol.
, vol.168
, pp. 58-59
-
-
Chapel, H.1
-
26
-
-
77956646451
-
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
-
Ferreira R.C., et al. Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency. Nat. Genet. 2010, 42:777-780.
-
(2010)
Nat. Genet.
, vol.42
, pp. 777-780
-
-
Ferreira, R.C.1
-
27
-
-
84857496758
-
High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency
-
Ferreira R.C., et al. High-density SNP mapping of the HLA region identifies multiple independent susceptibility loci associated with selective IgA deficiency. PLoS Genet. 2012, 8:e1002476.
-
(2012)
PLoS Genet.
, vol.8
-
-
Ferreira, R.C.1
-
28
-
-
78049347495
-
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
-
Strange A., et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat. Genet. 2010, 42:985-990.
-
(2010)
Nat. Genet.
, vol.42
, pp. 985-990
-
-
Strange, A.1
-
29
-
-
33745240931
-
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
-
Smyth D.J., et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat. Genet. 2006, 38:617-619.
-
(2006)
Nat. Genet.
, vol.38
, pp. 617-619
-
-
Smyth, D.J.1
-
30
-
-
65249131713
-
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
-
Nejentsev S., et al. Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 2009, 324:387-389.
-
(2009)
Science
, vol.324
, pp. 387-389
-
-
Nejentsev, S.1
-
31
-
-
82855177895
-
Selective IgA deficiency in autoimmune diseases
-
Wang N., et al. Selective IgA deficiency in autoimmune diseases. Mol. Med. 2011, 17:1383-1396.
-
(2011)
Mol. Med.
, vol.17
, pp. 1383-1396
-
-
Wang, N.1
-
32
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
Zhernakova A., et al. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat. Rev. Genet. 2009, 10:43-55.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
-
33
-
-
84859638338
-
Use of genome-wide association studies for drug repositioning
-
Sanseau P., et al. Use of genome-wide association studies for drug repositioning. Nat. Biotechnol. 2012, 30:317-320.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 317-320
-
-
Sanseau, P.1
-
34
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A., et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet. 2010, 42:1118-1125.
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
-
35
-
-
79954423741
-
The MHC, disease and selection
-
Trowsdale J. The MHC, disease and selection. Immunol. Lett. 2011, 137:1-8.
-
(2011)
Immunol. Lett.
, vol.137
, pp. 1-8
-
-
Trowsdale, J.1
-
36
-
-
0032829704
-
Haldane J.B.S. (1949) on infectious disease and evolution
-
Lederberg J. Haldane J.B.S. (1949) on infectious disease and evolution. Genetics 1999, 153:1-3.
-
(1999)
Genetics
, vol.153
, pp. 1-3
-
-
Lederberg, J.1
-
37
-
-
77953231426
-
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection
-
Zhernakova A., et al. Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am. J. Hum. Genet. 2010, 86:970-977.
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 970-977
-
-
Zhernakova, A.1
-
38
-
-
70350015386
-
The human major histocompatibility complex as a paradigm in genomics research
-
Vandiedonck C., Knight J.C. The human major histocompatibility complex as a paradigm in genomics research. Brief. Funct. Genomic Proteomic 2009, 8:379-394.
-
(2009)
Brief. Funct. Genomic Proteomic
, vol.8
, pp. 379-394
-
-
Vandiedonck, C.1
Knight, J.C.2
-
39
-
-
84856246802
-
De novo assembly and genotyping of variants using colored de Bruijn graphs
-
Iqbal Z., et al. De novo assembly and genotyping of variants using colored de Bruijn graphs. Nat. Genet. 2012, 44:226-232.
-
(2012)
Nat. Genet.
, vol.44
, pp. 226-232
-
-
Iqbal, Z.1
-
40
-
-
38749115455
-
A statistical method for predicting classical HLA alleles from SNP data
-
Leslie S., et al. A statistical method for predicting classical HLA alleles from SNP data. Am. J. Hum. Genet. 2008, 82:48-56.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 48-56
-
-
Leslie, S.1
-
41
-
-
48249152172
-
Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms
-
Monsuur A.J., et al. Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms. PLoS ONE 2008, 3:e2270.
-
(2008)
PLoS ONE
, vol.3
-
-
Monsuur, A.J.1
-
42
-
-
84855522599
-
Dysregulation of immune homeostasis in autoimmune diseases
-
Kuchroo V.K., et al. Dysregulation of immune homeostasis in autoimmune diseases. Nat. Med. 2012, 18:42-47.
-
(2012)
Nat. Med.
, vol.18
, pp. 42-47
-
-
Kuchroo, V.K.1
-
43
-
-
84862776511
-
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
-
Raychaudhuri S., et al. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat. Genet. 2012, 44:291-296.
-
(2012)
Nat. Genet.
, vol.44
, pp. 291-296
-
-
Raychaudhuri, S.1
-
44
-
-
79960899377
-
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
-
Evans D.M., et al. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat. Genet. 2011, 43:761-767.
-
(2011)
Nat. Genet.
, vol.43
, pp. 761-767
-
-
Evans, D.M.1
-
45
-
-
84869026015
-
Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondyloarthritis
-
Payeli S.K., et al. Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondyloarthritis. Arthritis Rheum. 2012, 64:3139-3149.
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 3139-3149
-
-
Payeli, S.K.1
-
46
-
-
82455192837
-
Copy number variation of KIR genes influences HIV-1 control
-
Pelak K., et al. Copy number variation of KIR genes influences HIV-1 control. PLoS Biol. 2011, 9:e1001208.
-
(2011)
PLoS Biol.
, vol.9
-
-
Pelak, K.1
-
47
-
-
59149087627
-
Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
-
Silverberg M.S., et al. Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat. Genet. 2009, 41:216-220.
-
(2009)
Nat. Genet.
, vol.41
, pp. 216-220
-
-
Silverberg, M.S.1
-
48
-
-
84860317030
-
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles
-
Fairfax B.P., et al. Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nat. Genet. 2012, 44:502-510.
-
(2012)
Nat. Genet.
, vol.44
, pp. 502-510
-
-
Fairfax, B.P.1
-
49
-
-
73249122274
-
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases
-
Rioux J.D., et al. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:18680-18685.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 18680-18685
-
-
Rioux, J.D.1
-
50
-
-
70649112117
-
HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C
-
Thomas R., et al. HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C. Nat. Genet. 2009, 41:1290-1294.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1290-1294
-
-
Thomas, R.1
-
51
-
-
85027933982
-
Differential microRNA regulation of HLA-C expression and its association with HIV control
-
Kulkarni S., et al. Differential microRNA regulation of HLA-C expression and its association with HIV control. Nature 2011, 472:495-498.
-
(2011)
Nature
, vol.472
, pp. 495-498
-
-
Kulkarni, S.1
-
52
-
-
79959412801
-
Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex
-
Vandiedonck C., et al. Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex. Genome Res. 2011, 21:1042-1054.
-
(2011)
Genome Res.
, vol.21
, pp. 1042-1054
-
-
Vandiedonck, C.1
-
53
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson W., et al. Mapping complex disease traits with global gene expression. Nat. Rev. Genet. 2009, 10:184-194.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 184-194
-
-
Cookson, W.1
-
54
-
-
33750204290
-
Genetics of global gene expression
-
Rockman M.V., Kruglyak L. Genetics of global gene expression. Nat. Rev. Genet. 2006, 7:862-872.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 862-872
-
-
Rockman, M.V.1
Kruglyak, L.2
-
55
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt M.F., et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007, 448:470-473.
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
-
56
-
-
84857487802
-
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
-
Fu J., et al. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet. 2012, 8:e1002431.
-
(2012)
PLoS Genet.
, vol.8
-
-
Fu, J.1
-
57
-
-
80052322958
-
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
-
Fehrmann R.S., et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet. 2011, 7:e1002197.
-
(2011)
PLoS Genet.
, vol.7
-
-
Fehrmann, R.S.1
-
58
-
-
79952256739
-
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study
-
Nica A.C., et al. The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet. 2011, 7:e1002003.
-
(2011)
PLoS Genet.
, vol.7
-
-
Nica, A.C.1
-
59
-
-
61449229760
-
Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13
-
Plagnol V., et al. Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13. Biostatistics 2009, 10:327-334.
-
(2009)
Biostatistics
, vol.10
, pp. 327-334
-
-
Plagnol, V.1
-
60
-
-
59249102648
-
Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene
-
Reich D., et al. Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene. PLoS Genet. 2009, 5:e1000360.
-
(2009)
PLoS Genet.
, vol.5
-
-
Reich, D.1
-
61
-
-
79959824142
-
Multiple loci are associated with white blood cell phenotypes
-
Nalls M.A., et al. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011, 7:e1002113.
-
(2011)
PLoS Genet.
, vol.7
-
-
Nalls, M.A.1
-
62
-
-
84858980097
-
Common genetic factors for hematological traits in humans
-
Okada Y., Kamatani Y. Common genetic factors for hematological traits in humans. J. Hum. Genet. 2012, 57:161-169.
-
(2012)
J. Hum. Genet.
, vol.57
, pp. 161-169
-
-
Okada, Y.1
Kamatani, Y.2
-
63
-
-
77952473808
-
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count
-
Okada Y., et al. Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. Hum. Mol. Genet. 2010, 19:2079-2085.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 2079-2085
-
-
Okada, Y.1
-
64
-
-
77649184039
-
Genome-wide association study of hematological and biochemical traits in a Japanese population
-
Kamatani Y., et al. Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat. Genet. 2010, 42:210-215.
-
(2010)
Nat. Genet.
, vol.42
, pp. 210-215
-
-
Kamatani, Y.1
-
65
-
-
84866406017
-
DNA methylation: a promising landscape for immune system-related diseases
-
Suarez-Alvarez B., et al. DNA methylation: a promising landscape for immune system-related diseases. Trends Genet. 2012, 28:506-514.
-
(2012)
Trends Genet.
, vol.28
, pp. 506-514
-
-
Suarez-Alvarez, B.1
-
66
-
-
84861483169
-
Genes, epigenetic regulation and environmental factors: which is the most relevant in developing autoimmune diseases?
-
Costenbader K.H., et al. Genes, epigenetic regulation and environmental factors: which is the most relevant in developing autoimmune diseases?. Autoimmun. Rev. 2012, 11:604-609.
-
(2012)
Autoimmun. Rev.
, vol.11
, pp. 604-609
-
-
Costenbader, K.H.1
-
67
-
-
73449089454
-
Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis
-
Karlson E.W., et al. Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis. Ann. Rheum. Dis. 2010, 69:54-60.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 54-60
-
-
Karlson, E.W.1
-
68
-
-
44849127693
-
Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking
-
Costenbader K.H., et al. Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking. Arthritis Res. Ther. 2008, 10:R52.
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Costenbader, K.H.1
-
69
-
-
77956885532
-
A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution
-
Ramagopalan S.V., et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution. Genome Res. 2010, 20:1352-1360.
-
(2010)
Genome Res.
, vol.20
, pp. 1352-1360
-
-
Ramagopalan, S.V.1
-
70
-
-
61449102631
-
Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D
-
Ramagopalan S.V., et al. Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. PLoS Genet. 2009, 5:e1000369.
-
(2009)
PLoS Genet.
, vol.5
-
-
Ramagopalan, S.V.1
-
71
-
-
84857037947
-
The genomics of autoimmune disease in the era of genome-wide association studies and beyond
-
Lessard C.J., et al. The genomics of autoimmune disease in the era of genome-wide association studies and beyond. Autoimmun. Rev. 2012, 11:267-275.
-
(2012)
Autoimmun. Rev.
, vol.11
, pp. 267-275
-
-
Lessard, C.J.1
-
72
-
-
37249006192
-
New links to the pathogenesis of Crohn disease provided by genome-wide association scans
-
Mathew C.G. New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat. Rev. Genet. 2008, 9:9-14.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 9-14
-
-
Mathew, C.G.1
-
73
-
-
61549115034
-
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease
-
Wang K., et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. Am. J. Hum. Genet. 2009, 84:399-405.
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 399-405
-
-
Wang, K.1
-
74
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini N., et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat. Genet. 2004, 36:337-338.
-
(2004)
Nat. Genet.
, vol.36
, pp. 337-338
-
-
Bottini, N.1
-
75
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
McCarthy M.I., et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat. Rev. Genet. 2008, 9:356-369.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
-
77
-
-
84864659874
-
HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria
-
Shui J.W., et al. HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria. Nature 2012, 488:222-225.
-
(2012)
Nature
, vol.488
, pp. 222-225
-
-
Shui, J.W.1
-
78
-
-
84865261493
-
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis
-
Gregory A.P., et al. TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. Nature 2012, 488:508-511.
-
(2012)
Nature
, vol.488
, pp. 508-511
-
-
Gregory, A.P.1
-
79
-
-
80052918929
-
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment
-
Hodges E., et al. Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol. Cell 2011, 44:17-28.
-
(2011)
Mol. Cell
, vol.44
, pp. 17-28
-
-
Hodges, E.1
-
80
-
-
5444222634
-
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription
-
Maier H., et al. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat. Immunol. 2004, 5:1069-1077.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1069-1077
-
-
Maier, H.1
-
81
-
-
33747849302
-
Accessibility control of V(D)J recombination
-
Cobb R.M., et al. Accessibility control of V(D)J recombination. Adv. Immunol. 2006, 91:45-109.
-
(2006)
Adv. Immunol.
, vol.91
, pp. 45-109
-
-
Cobb, R.M.1
-
82
-
-
84865119423
-
Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes
-
Quintin J., et al. Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. Cell Host Microbe 2012, 12:223-232.
-
(2012)
Cell Host Microbe
, vol.12
, pp. 223-232
-
-
Quintin, J.1
-
83
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler E.E., et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nat. Rev. Genet. 2010, 11:446-450.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 446-450
-
-
Eichler, E.E.1
-
84
-
-
79551505365
-
Massively parallel sequencing and rare disease
-
Ng S.B., et al. Massively parallel sequencing and rare disease. Hum. Mol. Genet. 2010, 19:R119-R124.
-
(2010)
Hum. Mol. Genet.
, vol.19
-
-
Ng, S.B.1
-
85
-
-
84862068459
-
Genetic variation in Toll-like receptors and disease susceptibility
-
Netea M.G., et al. Genetic variation in Toll-like receptors and disease susceptibility. Nat. Immunol. 2012, 13:535-542.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 535-542
-
-
Netea, M.G.1
|