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Volumn 99, Issue 12, 2012, Pages 1153-1160

Cancer stem cells, cornerstone of radioresistance and perspectives for radiosensitization: Glioblastoma as an example;Facteurs de radiorésistance des cellules souches cancéreuses et perspectives de radiosensibilisation: L'Exemple du glioblastome

Author keywords

Cancer stem cells; Hypoxia; Radiation therapy; Radioresistance

Indexed keywords

RADIOSENSITIZING AGENT;

EID: 84872287973     PISSN: 00074551     EISSN: 17696917     Source Type: Journal    
DOI: 10.1684/bdc.2012.1666     Document Type: Article
Times cited : (17)

References (61)
  • 1
    • 70349547152 scopus 로고    scopus 로고
    • Identification and targeting of cancer stem cells
    • Schatton T, Frank NY, Frank MH. Identification and targeting of cancer stem cells. Bioessays 2009; 10 : 1038-49.
    • (2009) Bioessays , vol.10 , pp. 1038-1049
    • Schatton, T.1    Frank, N.Y.2    Frank, M.H.3
  • 3
    • 59049106578 scopus 로고    scopus 로고
    • Crypts stem cells as the cells-of-origin of intestinal cancer
    • Barker N, Ridgway RA, van Es JH, et al. Crypts stem cells as the cells-of-origin of intestinal cancer. Nature 2009; 457 : 608-11.
    • (2009) Nature , vol.457 , pp. 608-611
    • Barker, N.1    Ridgway, R.A.2    Van Es, J.H.3
  • 4
    • 59049087696 scopus 로고    scopus 로고
    • Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
    • Zhu L, Gibson P, Currle DS, et al. Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature 2009; 45 : 603-7.
    • (2009) Nature , vol.45 , pp. 603-607
    • Zhu, L.1    Gibson, P.2    Currle, D.S.3
  • 5
    • 57849109837 scopus 로고    scopus 로고
    • Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
    • Alcantara Llaguno S, Chen J, Kwon CH, et al. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 2009; 15 : 45-56.
    • (2009) Cancer Cell , vol.15 , pp. 45-56
    • Alcantara Llaguno, S.1    Chen, J.2    Kwon, C.H.3
  • 7
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K,Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9 : 265-73.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 8
    • 79956351015 scopus 로고    scopus 로고
    • Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
    • Chaffer CL, Brueckmann I, Scheel C, et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci U S A 2011; 108 : 7950-5.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7950-7955
    • Chaffer, C.L.1    Brueckmann, I.2    Scheel, C.3
  • 9
    • 77950972011 scopus 로고    scopus 로고
    • Radiation resistance of cancer stem cells: The 4 R's of radiobiology revisited
    • Pajonk F, Vlashi E, McBride WH. Radiation resistance of cancer stem cells: the 4 R's of radiobiology revisited. Stem Cells 2010; 28 : 639-48.
    • (2010) Stem Cells , vol.28 , pp. 639-648
    • Pajonk, F.1    Vlashi, E.2    McBride, W.H.3
  • 10
    • 60649100252 scopus 로고    scopus 로고
    • Cancer stem cells and tumour response to therapy: Current problems and future prospects
    • Mils L, Hittelman WN. Cancer stem cells and tumour response to therapy: current problems and future prospects. Semin Radiat Oncol 2009; 19 : 96-105.
    • (2009) Semin Radiat Oncol , vol.19 , pp. 96-105
    • Mils, L.1    Hittelman, W.N.2
  • 11
    • 45849089879 scopus 로고    scopus 로고
    • Exploring the role of cancer stem cells in radioresistance
    • DOI 10.1038/nrc2419, PII NRC2419
    • Baumann M, Krause M, Hill R. Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer 2008; 8 : 545-54. (Pubitemid 351881850)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.7 , pp. 545-554
    • Baumann, M.1    Krause, M.2    Hill, R.3
  • 14
    • 78649446893 scopus 로고    scopus 로고
    • Role of lymphocyte-specific protein tyrosine kinase (LCK) in the expansion of glioma-initiating cells by fractionated radiation
    • Kim RK, Yoon CH, Hyun KH, et al. Role of lymphocyte-specific protein tyrosine kinase (LCK) in the expansion of glioma-initiating cells by fractionated radiation. Biochem Biophys Res Commun 2010; 402 : 631-6.
    • (2010) Biochem Biophys Res Commun , vol.402 , pp. 631-636
    • Kim, R.K.1    Yoon, C.H.2    Hyun, K.H.3
  • 16
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • Wilson A, Laurenti E, Oser G, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 2008; 135 : 1118-29.
    • (2008) Cell , vol.135 , pp. 1118-1129
    • Wilson, A.1    Laurenti, E.2    Oser, G.3
  • 17
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • DOI 10.1158/0008-5472.CAN-06-0858
    • Fan X, Matsui W, Khaki L, et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res 2006; 66 : 7445-52. (Pubitemid 44289197)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3    Stearns, D.4    Chun, J.5    Li, Y.-M.6    Eberhart, C.G.7
  • 18
    • 75349108271 scopus 로고    scopus 로고
    • Notch promotes radioresistance of glioma stem cells
    • Wang J, Wakeman TP, Lathia JD, et al. Notch promotes radioresistance of glioma stem cells. Stem Cells 2010; 28 : 17-28.
    • (2010) Stem Cells , vol.28 , pp. 17-28
    • Wang, J.1    Wakeman, T.P.2    Lathia, J.D.3
  • 19
    • 35148888629 scopus 로고    scopus 로고
    • Cancer stem cells in radiation resistance
    • DOI 10.1158/0008-5472.CAN-07-0895
    • Rich JN. Cancer stem cells in radiation resistance. Cancer Res 2007; 67 : 8980-4. (Pubitemid 47535877)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 8980-8984
    • Rich, J.N.1
  • 20
    • 77954218647 scopus 로고    scopus 로고
    • Potential therapeutic implications of cancer stem cells in glioblastoma
    • Cheng L, Bao S, Rich JN. Potential therapeutic implications of cancer stem cells in glioblastoma. Biochem Pharmacol 2010; 80 : 654-65.
    • (2010) Biochem Pharmacol , vol.80 , pp. 654-665
    • Cheng, L.1    Bao, S.2    Rich, J.N.3
  • 21
    • 29144487990 scopus 로고    scopus 로고
    • Role of Bmi-1 and Ring1A in H2A ubiquitylation and hox gene silencing
    • DOI 10.1016/j.molcel.2005.12.002, PII S1097276505018174
    • Cao R, Tsukada Y, Zhang Y. Role of BMI-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell 2005; 20 : 845-54. (Pubitemid 41814874)
    • (2005) Molecular Cell , vol.20 , Issue.6 , pp. 845-854
    • Cao, R.1    Tsukada, Y.-I.2    Zhang, Y.3
  • 22
    • 77955381770 scopus 로고    scopus 로고
    • BMI confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
    • Facchino S, Abdouh M, Chatoo W, et al. BMI confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J Neurosci 2010; 30 : 10096-111.
    • (2010) J Neurosci , vol.30 , pp. 10096-10111
    • Facchino, S.1    Abdouh, M.2    Chatoo, W.3
  • 23
    • 79952281817 scopus 로고    scopus 로고
    • L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1
    • Cheng L, Wu Q, Huang Z, et al. L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1. EMBO J 2011; 30 : 800-13.
    • (2011) EMBO J , vol.30 , pp. 800-813
    • Cheng, L.1    Wu, Q.2    Huang, Z.3
  • 24
    • 83355174034 scopus 로고    scopus 로고
    • Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines
    • Sarcar B, Kahali S, Prabhu AH, et al. Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines. Mol Cancer Ther 2011; 10 : 2405-14.
    • (2011) Mol Cancer Ther , vol.10 , pp. 2405-2414
    • Sarcar, B.1    Kahali, S.2    Prabhu, A.H.3
  • 25
    • 84858058074 scopus 로고    scopus 로고
    • The brain microenvironment preferentially enhances the radioresistance of CD133(+) glioblastoma stem-like cells
    • Jamal M, Rath BH, Tsang PS, et al. The brain microenvironment preferentially enhances the radioresistance of CD133(+) glioblastoma stem-like cells. Neoplasia 2012; 14 : 150-8.
    • (2012) Neoplasia , vol.14 , pp. 150-158
    • Jamal, M.1    Rath, B.H.2    Tsang, P.S.3
  • 28
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • Diehn M, Cho RW, Lobo NA, et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009; 458 : 780-3.
    • (2009) Nature , vol.458 , pp. 780-783
    • Diehn, M.1    Cho, R.W.2    Lobo, N.A.3
  • 29
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S,Wu Q, et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009; 15 : 501-13.
    • (2009) Cancer Cell , vol.15 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3
  • 30
    • 65549150903 scopus 로고    scopus 로고
    • Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro
    • McCord AM, Jamal M, Shankavarum UT, et al. Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro. Mol Cancer Res 2009; 7 : 489-97.
    • (2009) Mol Cancer Res , vol.7 , pp. 489-497
    • McCord, A.M.1    Jamal, M.2    Shankavarum, U.T.3
  • 31
    • 84861701350 scopus 로고    scopus 로고
    • Targeting a cornerstone of radiation resistance: Cancer stem cell
    • Moncharmont C, Levy A, Gilormini M, et al. Targeting a cornerstone of radiation resistance: cancer stem cell. Cancer Lett 2012; 322 : 139-47.
    • (2012) Cancer Lett , vol.322 , pp. 139-147
    • Moncharmont, C.1    Levy, A.2    Gilormini, M.3
  • 34
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOGGLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
    • Clement V, Sanchez P, de Tribolet N, et al. HEDGEHOGGLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. Curr Biol 2007; 17 : 165-72.
    • (2007) Curr Biol , vol.17 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    De Tribolet, N.3
  • 37
    • 44849106532 scopus 로고    scopus 로고
    • Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells
    • Soeda A, Inagaki A, Oka N, et al. Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem 2008; 283 : 10958-66.
    • (2008) J Biol Chem , vol.283 , pp. 10958-10966
    • Soeda, A.1    Inagaki, A.2    Oka, N.3
  • 38
    • 79952275286 scopus 로고    scopus 로고
    • Celecoxib and radioresistant glioblastoma-derived CD133+ cells: Improvement in radiotherapeutic effects. Laboratory investigation
    • Ma HI, Chiou SH, Hueng DY, et al. Celecoxib and radioresistant glioblastoma-derived CD133+ cells: improvement in radiotherapeutic effects. Laboratory investigation. J Neurosurg 2011; 114 : 651-62.
    • (2011) J Neurosurg , vol.114 , pp. 651-662
    • Ma, H.I.1    Chiou, S.H.2    Hueng, D.Y.3
  • 39
    • 84860855712 scopus 로고    scopus 로고
    • Inhibition of phosphorylated STAT3 by cucurbitacin i enhances chemoradiosensitivity in medulloblastoma-derived cancer stem cells
    • Chang CJ, Chiang CH, Song WS, et al. Inhibition of phosphorylated STAT3 by cucurbitacin I enhances chemoradiosensitivity in medulloblastoma-derived cancer stem cells. Childs Nerv Syst 2012; 28 : 363-73.
    • (2012) Childs Nerv Syst , vol.28 , pp. 363-373
    • Chang, C.J.1    Chiang, C.H.2    Song, W.S.3
  • 40
    • 84155184247 scopus 로고    scopus 로고
    • Resveratrol suppresses tumorigenicity and enhances radiosensitivity in primary glioblastoma tumor initiating cells by inhibiting the STAT3 axis
    • Yang YP, Chang YL, Huang PI, et al. Resveratrol suppresses tumorigenicity and enhances radiosensitivity in primary glioblastoma tumor initiating cells by inhibiting the STAT3 axis. J Cell Physiol 2012; 227 : 976-93.
    • (2012) J Cell Physiol , vol.227 , pp. 976-993
    • Yang, Y.P.1    Chang, Y.L.2    Huang, P.I.3
  • 41
    • 82655181475 scopus 로고    scopus 로고
    • Blockade of TGF-β signaling by the TGFßR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma
    • Zhang M, Kleber S, Röhrich M, et al. Blockade of TGF-β signaling by the TGFßR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma. Cancer Res 2011; 71 : 7155-67.
    • (2011) Cancer Res , vol.71 , pp. 7155-7167
    • Zhang, M.1    Kleber, S.2    Röhrich, M.3
  • 42
    • 42949149114 scopus 로고    scopus 로고
    • Glioblastoma-derived stem cell-enriched cultures from distinct subgroups according to molecular and phenotypic criteria
    • Günther HS, Schmidt NO, Phillips HS, et al. Glioblastoma-derived stem cell-enriched cultures from distinct subgroups according to molecular and phenotypic criteria. Oncogene 2008; 27 : 2897-9.
    • (2008) Oncogene , vol.27 , pp. 2897-2899
    • Günther, H.S.1    Schmidt, N.O.2    Phillips, H.S.3
  • 43
    • 84864863728 scopus 로고    scopus 로고
    • MET signaling regulates glioblastoma stem cells
    • Joo KM, Jin J, Kim E, et al. MET signaling regulates glioblastoma stem cells. Cancer Res 2012; 72 : 3828-38.
    • (2012) Cancer Res , vol.72 , pp. 3828-3838
    • Joo, K.M.1    Jin, J.2    Kim, E.3
  • 44
    • 84861705420 scopus 로고    scopus 로고
    • The radiosensitizing effects of a novel tyrosine kinase inhibitor, Mp470 in glioblastoma multiforme stem cells
    • Ellsworth R, Welsh J, Mahadevan D, et al. The radiosensitizing effects of a novel tyrosine kinase inhibitor, Mp470 in glioblastoma multiforme stem cells. Int J Radiat Oncol Biol Phys 2008; 72 : 714-5.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , pp. 714-715
    • Ellsworth, R.1    Welsh, J.2    Mahadevan, D.3
  • 46
    • 33847026354 scopus 로고    scopus 로고
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage
    • Abedin MJ, Wang D, McDonnell MA, et al. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ 2007; 14 : 500-10.
    • (2007) Cell Death Differ , vol.14 , pp. 500-510
    • Abedin, M.J.1    Wang, D.2    McDonnell, M.A.3
  • 47
    • 78651359429 scopus 로고    scopus 로고
    • Knockdown of the DNA-dependent protein kinase catalytic subunit radiosensitizes glioma-initiating cells by inducing autophagy
    • Zhuang W, Li B, Long L, et al. Knockdown of the DNA-dependent protein kinase catalytic subunit radiosensitizes glioma-initiating cells by inducing autophagy. Brain Res 2011 : 13717-815.
    • (2011) Brain Res , pp. 13717-13815
    • Zhuang, W.1    Li, B.2    Long, L.3
  • 48
    • 80052751118 scopus 로고    scopus 로고
    • Cilengitide induces autophagy-mediated cell death in glioma cells
    • Lomonaco SL, Finniss S, Xiang C, et al. Cilengitide induces autophagy-mediated cell death in glioma cells. Neuro Oncol 2011; 13 : 857-65.
    • (2011) Neuro Oncol , vol.13 , pp. 857-865
    • Lomonaco, S.L.1    Finniss, S.2    Xiang, C.3
  • 49
    • 84859856906 scopus 로고    scopus 로고
    • Gefitinib radiosensitizes stem-like glioma cells: Inhibition of epidermal growth factor receptor-Akt- DNA-PK signaling, accompanied by inhibition ofDNA double-strand break repair
    • Kang KB, Zhu C, Wong YL, et al. Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt- DNA-PK signaling, accompanied by inhibition ofDNA double-strand break repair. Int J Radiat Oncol Biol Phys 2012; 83 : 43-52.
    • (2012) Int J Radiat Oncol Biol Phys , vol.83 , pp. 43-52
    • Kang, K.B.1    Zhu, C.2    Wong, Y.L.3
  • 50
    • 39449135834 scopus 로고    scopus 로고
    • PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
    • DOI 10.1101/gad.1627008
    • Hambardzumyan D, Becher OJ, Rosenblum MK, et al. PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev 2008; 22 : 436-48. (Pubitemid 351272752)
    • (2008) Genes and Development , vol.22 , Issue.4 , pp. 436-448
    • Hambardzumyan, D.1    Becher, O.J.2    Rosenblum, M.K.3    Pandolfi, P.P.4    Manova-Todorova, K.5    Holland, E.C.6
  • 51
    • 61449191698 scopus 로고    scopus 로고
    • EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors
    • Li L, Dutra A, Pak E, et al. EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. Neuro Oncol 2009; 11 : 9-21.
    • (2009) Neuro Oncol , vol.11 , pp. 9-21
    • Li, L.1    Dutra, A.2    Pak, E.3
  • 53
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14 : 1837-51. (Pubitemid 30639518)
    • (2000) Genes and Development , vol.14 , Issue.15 , pp. 1837-1851
    • Polakis, P.1
  • 54
    • 81855217368 scopus 로고    scopus 로고
    • Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy
    • Kendziorra E, Ahlborn K, Spitzner M, et al. Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy. Carcinogenesis 2011; 32 : 1824-31.
    • (2011) Carcinogenesis , vol.32 , pp. 1824-1831
    • Kendziorra, E.1    Ahlborn, K.2    Spitzner, M.3
  • 55
    • 84867820011 scopus 로고    scopus 로고
    • Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance
    • Huang FT, Zhuan-Sun YX, Zhuang YY, et al. Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance. Int J Oncol 2012; 4 : 1707-14.
    • (2012) Int J Oncol , vol.4 , pp. 1707-1714
    • Huang, F.T.1    Zhuan-Sun, Y.X.2    Zhuang, Y.Y.3
  • 56
    • 84865316843 scopus 로고    scopus 로고
    • HEDGEHOG-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells
    • Santini R, Vinci MC, Pandolfi S, et al. HEDGEHOG-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells. Stem Cells 2012; 30 : 1808-18.
    • (2012) Stem Cells , vol.30 , pp. 1808-1818
    • Santini, R.1    Vinci, M.C.2    Pandolfi, S.3
  • 57
    • 79251492356 scopus 로고    scopus 로고
    • Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells
    • Hsieh A, Ellsworth R, Hsieh D. Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells. J Cell Physiol 2011; 226 : 1118-27.
    • (2011) J Cell Physiol , vol.226 , pp. 1118-1127
    • Hsieh, A.1    Ellsworth, R.2    Hsieh, D.3
  • 58
    • 79953724966 scopus 로고    scopus 로고
    • Proton therapy targets cancer stem cells in treatment-resistant non-small cell lung cancer
    • Chang JY, Zhang X, Vassiliev O, et al. Proton therapy targets cancer stem cells in treatment-resistant non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2010; 78 : 644.
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 644
    • Chang, J.Y.1    Zhang, X.2    Vassiliev, O.3
  • 59
    • 79956095898 scopus 로고    scopus 로고
    • Effects of carbon ion beam on putative colon cancer stem cells and its comparison with X-rays
    • Cui X, Oonishi K, Tsujii H, et al. Effects of carbon ion beam on putative colon cancer stem cells and its comparison with X-rays. Cancer Res 2011; 71 : 3676-87.
    • (2011) Cancer Res , vol.71 , pp. 3676-3687
    • Cui, X.1    Oonishi, K.2    Tsujii, H.3
  • 60
    • 84864287761 scopus 로고    scopus 로고
    • Can irradiation of potential cancer stem-cell niche in the subventricular zone influence survival in patients with newly diagnosed glioblastoma?
    • Gupta T, Nair V, Paul SN, et al. Can irradiation of potential cancer stem-cell niche in the subventricular zone influence survival in patients with newly diagnosed glioblastoma? J Neurooncol 2012; 109 : 195-203.
    • (2012) J Neurooncol , vol.109 , pp. 195-203
    • Gupta, T.1    Nair, V.2    Paul, S.N.3
  • 61
    • 62349116134 scopus 로고    scopus 로고
    • In-vivo imaging, tracking, and targeting of cancer stem cells
    • Vlashi E, Kim K, Dealla DL, et al. In-vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst 2009; 101 : 350-9.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 350-359
    • Vlashi, E.1    Kim, K.2    Dealla, D.L.3


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