Hepatic mRNA, microRNA, and miR-34a-Target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation

Environmental and Molecular Mutagenesis

Volumn 53, Issue 1, 2012, Pages 10-21

  Malik, Amal I ^a   Williams, Andrew ^a   Lemieux, Christine L ^a   White, Paul A ^a   Yauk, Carole L ^a  

^a HEALTH CANADA   (Canada)

Author keywords

Apoptosis; DNA adducts; LacZ mutation; MiR 34a; P53; Toxicogenomics

Indexed keywords

BENZO[A]PYRENE; BETA GALACTOSIDASE; MESSENGER RNA; MICRORNA; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; GENE TARGETING; GENETIC TRANSCRIPTION; IMMUNE RESPONSE; LIVER; MALE; MICROARRAY ANALYSIS; MOUSE; MUTAGENICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN TARGETING; TRANSGENE; XENOBIOTIC METABOLISM;

ANIMALS; BENZO(A)PYRENE; BLOTTING, WESTERN; COMPUTATIONAL BIOLOGY; DNA ADDUCTS; DNA DAMAGE; LIVER; MALE; MICE; MICROARRAY ANALYSIS; MICRORNAS; MUTAGENS; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MUS;

EID: 84855467600     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20668     Document Type: Article

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