-
1
-
-
0027443904
-
Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
-
Abdel-Razzak Z, Loyer P, Fautrel A, Gautier JC, Corcos L, Turlin B, Beaune P, Guillouzo A. 1993. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 44: 707-715.
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 707-715
-
-
Abdel-Razzak, Z.1
Loyer, P.2
Fautrel, A.3
Gautier, J.C.4
Corcos, L.5
Turlin, B.6
Beaune, P.7
Guillouzo, A.8
-
2
-
-
0242416575
-
Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights
-
Agnello D, Lankford CS, Bream J, Morinobu A, Gadina M, O'Shea JJ, Frucht DM. 2003. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J. Clin. Immunol. 23: 147-161.
-
(2003)
J. Clin. Immunol.
, vol.23
, pp. 147-161
-
-
Agnello, D.1
Lankford, C.S.2
Bream, J.3
Morinobu, A.4
Gadina, M.5
O'Shea, J.J.6
Frucht, D.M.7
-
3
-
-
0034693950
-
Mast cell control neutrophil recruitment during T cell-mediated delayed hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2
-
Biedermann BT, Knelling M, Mailhammer R, Maier K, Sander CA, Kollias G, Kunkel S L, Hultner L, Rocken M. 2000. Mast cell control neutrophil recruitment during T cell-mediated delayed hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2. J. Exp. Med. 192: 1441-1451.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1441-1451
-
-
Biedermann, B.T.1
Knelling, M.2
Mailhammer, R.3
Maier, K.4
Sander, C.A.5
Kollias, G.6
Kunkel, S.L.7
Hultner, L.8
Rocken, M.9
-
4
-
-
33745226462
-
Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical Cyp1a inducers
-
doi: 10.1124/dmd.105.009159.
-
Coe KJ, Nelson SD, Ulrich RG, He Y, Dai X, Cheng O, Caguyoung M, Roberts CJ, Slatter JG. 2006. Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical Cyp1a inducers. Drug Metab. Dispos. 34: 1266-1275; doi: 10.1124/dmd.105.009159.
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 1266-1275
-
-
Coe, K.J.1
Nelson, S.D.2
Ulrich, R.G.3
He, Y.4
Dai, X.5
Cheng, O.6
Caguyoung, M.7
Roberts, C.J.8
Slatter, J.G.9
-
5
-
-
0023655369
-
Protein damage and degradation by oxygen radicals
-
Davies KJA. 1987. Protein damage and degradation by oxygen radicals. J. Biol. Chem. 262: 9895-9901.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9895-9901
-
-
Davies, K.J.A.1
-
7
-
-
0028240927
-
Toxicity of the antiandrogen flutamide in isolated rat hepatocytes
-
Fau D, Eugene D, Berson A, Letteron P, Fromenty B, Fisch C, Pessayre D. 1994. Toxicity of the antiandrogen flutamide in isolated rat hepatocytes. J. Pharmacol. Exp. Ther. 269: 954-962.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 954-962
-
-
Fau, D.1
Eugene, D.2
Berson, A.3
Letteron, P.4
Fromenty, B.5
Fisch, C.6
Pessayre, D.7
-
8
-
-
0026594568
-
Incidence of liver toxicity associated with the use of flutamide in prostate cancer patients
-
Gomez J, Dupont A, Cuan L, Tremblay M, Suburu R, Lemay M, Labrie, F. 1992. Incidence of liver toxicity associated with the use of flutamide in prostate cancer patients. Am. J. Med. 92: 465-470.
-
(1992)
Am. J. Med.
, vol.92
, pp. 465-470
-
-
Gomez, J.1
Dupont, A.2
Cuan, L.3
Tremblay, M.4
Suburu, R.5
Lemay, M.6
Labrie, F.7
-
9
-
-
0030961762
-
In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset
-
doi: 10.1002/hep.510250402.
-
Harada K, Water JV, Leung PSC, Coppel RL, Ansari A, Nakanuma Y, Gershwin ME. 1997. In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset. Hepatology 25: 791-796; doi: 10.1002/hep.510250402.
-
(1997)
Hepatology
, vol.25
, pp. 791-796
-
-
Harada, K.1
Water, J.V.2
Leung, P.S.C.3
Coppel, R.L.4
Ansari, A.5
Nakanuma, Y.6
Gershwin, M.E.7
-
11
-
-
0036137543
-
Current and novel immunosuppressive therapy for autoimmune hepatitis
-
doi: 10.1053/jhep.2002.30991.
-
Heneghan MA, McFarlane IG. 2002. Current and novel immunosuppressive therapy for autoimmune hepatitis. Hepatology 35: 7-13; doi: 10.1053/jhep.2002.30991.
-
(2002)
Hepatology
, vol.35
, pp. 7-13
-
-
Heneghan, M.A.1
McFarlane, I.G.2
-
12
-
-
78651090716
-
IL-4 mediates dicloxacillin-induced liver injury in mice
-
doi: 10.1016/j.toxlet.2010.11.006.
-
Higuchi S, Kobayashi M, Yoshikawa Y, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. 2011. IL-4 mediates dicloxacillin-induced liver injury in mice. Toxicol. Lett. 200: 139-145; doi: 10.1016/j.toxlet.2010.11.006.
-
(2011)
Toxicol. Lett.
, vol.200
, pp. 139-145
-
-
Higuchi, S.1
Kobayashi, M.2
Yoshikawa, Y.3
Tsuneyama, K.4
Fukami, T.5
Nakajima, M.6
Yokoi, T.7
-
13
-
-
0032145438
-
-
Hogan SP, Matthaei KI, Young JM, Koskinen A, Young IG, Foster PS. 1998. A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/c mice independently of IL-4 and IL-5. 161: 1501-1509.
-
(1998)
A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/c mice independently of IL-4 and IL-5
, vol.161
, pp. 1501-1509
-
-
Hogan, S.P.1
Matthaei, K.I.2
Young, J.M.3
Koskinen, A.4
Young, I.G.5
Foster, P.S.6
-
14
-
-
33645799020
-
Mechanisms of drug-induced liver injury
-
doi: 10.1208/aapsj080106.
-
Holt MP, Ju C. 2006. Mechanisms of drug-induced liver injury. AAPS J. 8: E48-E54; doi: 10.1208/aapsj080106.
-
(2006)
AAPS J.
, vol.8
-
-
Holt, M.P.1
Ju, C.2
-
15
-
-
33748307666
-
Role of neutrophils in acute inflammatory liver injury
-
doi: 10.1111/j.1478-3231.2006.01327.x.
-
Jaeschke H, Hasegawa T. 2006. Role of neutrophils in acute inflammatory liver injury. Liver Int. 26: 912-919; doi: 10.1111/j.1478-3231.2006.01327.x.
-
(2006)
Liver Int.
, vol.26
, pp. 912-919
-
-
Jaeschke, H.1
Hasegawa, T.2
-
16
-
-
0042834253
-
Crucial role of IL-4/STAT6 in T cell-mediated hepatitis: up-regulating eotaxins and IL-5 and recruiting leukoctyes
-
Jaruga B, Hong F, Sun R, Radaeva S, Gao B. 2003. Crucial role of IL-4/STAT6 in T cell-mediated hepatitis: up-regulating eotaxins and IL-5 and recruiting leukoctyes. J. Immunol. 171: 3233-3244.
-
(2003)
J. Immunol.
, vol.171
, pp. 3233-3244
-
-
Jaruga, B.1
Hong, F.2
Sun, R.3
Radaeva, S.4
Gao, B.5
-
17
-
-
67349231918
-
Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity
-
doi: 10.1016/j.taap.2009.05.007.
-
Kashimshetty R, Desai VG, Kale VM, Lee T, Moland CL, Branham WS, New LS, Chan ECY, Younis H, Boelsterli UA. 2009. Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity. Toxicol. Appl. Pharmacol. 238: 150-159; doi: 10.1016/j.taap.2009.05.007.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.238
, pp. 150-159
-
-
Kashimshetty, R.1
Desai, V.G.2
Kale, V.M.3
Lee, T.4
Moland, C.L.5
Branham, W.S.6
New, L.S.7
Chan, E.C.Y.8
Younis, H.9
Boelsterli, U.A.10
-
18
-
-
0035804276
-
Allergy and allergic diseases
-
doi: 10.1056/NEJM200101043440106.
-
Kay AB. 2001. Allergy and allergic diseases. New Engl. J. Med. 344: 30-37; doi: 10.1056/NEJM200101043440106.
-
(2001)
New Engl. J. Med.
, vol.344
, pp. 30-37
-
-
Kay, A.B.1
-
19
-
-
0041917266
-
Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease
-
Kidd P. 2003. Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Altern. Med. Rev. 8: 223-246.
-
(2003)
Altern. Med. Rev.
, vol.8
, pp. 223-246
-
-
Kidd, P.1
-
20
-
-
0035053878
-
The lymphoid liver: considerations on pathways to autoimmune injury
-
Kita H, Macky IR, Van DWJ, Gershwin ME. 2001. The lymphoid liver: considerations on pathways to autoimmune injury. Gastroenterology 120: 1485-1501.
-
(2001)
Gastroenterology
, vol.120
, pp. 1485-1501
-
-
Kita, H.1
Macky, I.R.2
Van, D.W.J.3
Gershwin, M.E.4
-
21
-
-
70349298831
-
Halothane-induced liver injury is mediated by interleukin-17 in mice
-
doi: 10.1093/toxsci/kfp165.
-
Kobayashi E, Kobayashi M, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. 2009. Halothane-induced liver injury is mediated by interleukin-17 in mice. Toxicol. Sci. 111: 302-310; doi: 10.1093/toxsci/kfp165.
-
(2009)
Toxicol. Sci.
, vol.111
, pp. 302-310
-
-
Kobayashi, E.1
Kobayashi, M.2
Tsuneyama, K.3
Fukami, T.4
Nakajima, M.5
Yokoi, T.6
-
22
-
-
33646073728
-
Emerging roles of DP and CRTh2 in allergic inflammation
-
doi: 10.1016/j.molmed.2006.02.005.
-
Kostenis E, Ulven T. 2006. Emerging roles of DP and CRTh2 in allergic inflammation. Trends Mol. Med. 12: 148-158; doi: 10.1016/j.molmed.2006.02.005.
-
(2006)
Trends Mol. Med.
, vol.12
, pp. 148-158
-
-
Kostenis, E.1
Ulven, T.2
-
23
-
-
0031919849
-
Jaks and STATs: biological implications
-
doi: 10.1146/annurev.immunol.16.1.293.
-
Leonard WJ, O'Shea JJ. 1998. Jaks and STATs: biological implications. Annu. Rev. Immunol. 16: 293-322; doi: 10.1146/annurev.immunol.16.1.293.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
24
-
-
33645838033
-
Metabolism and hepatic toxicity of flutamide in cytochrome P450 1A2 knockout SV129 mice
-
doi: 10.1007/s00535-005-1749-y.
-
Matsuzaki Y, Nagai D, Ichimura E, Goda R, Tomura A, Doi M, Nishikawa K. 2006. Metabolism and hepatic toxicity of flutamide in cytochrome P450 1A2 knockout SV129 mice. J. Gastroenterol. 41: 231-239; doi: 10.1007/s00535-005-1749-y.
-
(2006)
J. Gastroenterol.
, vol.41
, pp. 231-239
-
-
Matsuzaki, Y.1
Nagai, D.2
Ichimura, E.3
Goda, R.4
Tomura, A.5
Doi, M.6
Nishikawa, K.7
-
26
-
-
0025834271
-
Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction
-
Montgomery RA, Dallman MJ. 1991. Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J. Immunol. 147: 554-560.
-
(1991)
J. Immunol.
, vol.147
, pp. 554-560
-
-
Montgomery, R.A.1
Dallman, M.J.2
-
27
-
-
67649408722
-
Drug-induced hepatotoxicity test using γ-glutamylcysteine synthetase knockdown rat
-
doi:10.1016/j.toxlet.2009.05.016.
-
Morita M, Akai S, Hosomi H, Tsuneyama K, Nakajima M, Yokoi T. 2009. Drug-induced hepatotoxicity test using γ-glutamylcysteine synthetase knockdown rat. Toxicol. Lett. 189: 159-165; doi:10.1016/j.toxlet.2009.05.016.
-
(2009)
Toxicol. Lett.
, vol.189
, pp. 159-165
-
-
Morita, M.1
Akai, S.2
Hosomi, H.3
Tsuneyama, K.4
Nakajima, M.5
Yokoi, T.6
-
28
-
-
58149467011
-
Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity
-
doi: 10.1124/dmd.108.021964.
-
Ohbuchi M, Miyata M, Nagai D, Shimada M, Yoshinari K, Yamazoe Y. 2009. Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity. Drug Metab. Dispos. 37: 97-105; doi: 10.1124/dmd.108.021964.
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 97-105
-
-
Ohbuchi, M.1
Miyata, M.2
Nagai, D.3
Shimada, M.4
Yoshinari, K.5
Yamazoe, Y.6
-
29
-
-
0036147503
-
Cytokines serum levels in patients with chronic HCV infection
-
Spanakis NE, Garinis GA, Alexopoulos EC, Patrinos GP, Menounos PG, Sklavounou A, Manolis NE, Gorgoulis VG, Valis D. 2002. Cytokines serum levels in patients with chronic HCV infection. J. Clin. Lab. Anal. 16: 40-46.
-
(2002)
J. Clin. Lab. Anal.
, vol.16
, pp. 40-46
-
-
Spanakis, N.E.1
Garinis, G.A.2
Alexopoulos, E.C.3
Patrinos, G.P.4
Menounos, P.G.5
Sklavounou, A.6
Manolis, N.E.7
Gorgoulis, V.G.8
Valis, D.9
-
30
-
-
14844346424
-
Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse
-
Spik I, Brenuchon C, Angeli V, Staumont D, Fleury S, Capron M, Trottein F, Dombrowicz D. 2005. Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse. J. Immunol. 174: 3703-3708.
-
(2005)
J. Immunol.
, vol.174
, pp. 3703-3708
-
-
Spik, I.1
Brenuchon, C.2
Angeli, V.3
Staumont, D.4
Fleury, S.5
Capron, M.6
Trottein, F.7
Dombrowicz, D.8
-
31
-
-
0030993242
-
Alteration by flutamide of neutrophil response to stimulation. Implications for tissue injury
-
Srinivasan R, Buchweitz JP, Ganey PE. 1997. Alteration by flutamide of neutrophil response to stimulation. Implications for tissue injury. Biochem. Pharmacol. 53: 1179-1185.
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 1179-1185
-
-
Srinivasan, R.1
Buchweitz, J.P.2
Ganey, P.E.3
-
32
-
-
33846966636
-
A brief history of Th17, the first major revision in the Th1/Th2 hypothesis if T cell-mediated tissue damage
-
doi: 10.1038/nm1551.
-
Steinman L. 2007. A brief history of Th17, the first major revision in the Th1/Th2 hypothesis if T cell-mediated tissue damage. Nat. Rev. Med. 13: 139-145; doi: 10.1038/nm1551.
-
(2007)
Nat. Rev. Med.
, vol.13
, pp. 139-145
-
-
Steinman, L.1
-
33
-
-
3242722422
-
CRTH2 is a prominent effector in contact hypersensitivity-induced neutrophil inflammation
-
doi: 10.1093/intimm/dxh096.
-
Takeshita K, Yamasaki T, Nagano K, Sugimoto H, Shichijo M, Gantner F, Bacon BK. 2004. CRTH2 is a prominent effector in contact hypersensitivity-induced neutrophil inflammation. Int. Immunol. 16: 947-959; doi: 10.1093/intimm/dxh096.
-
(2004)
Int. Immunol.
, vol.16
, pp. 947-959
-
-
Takeshita, K.1
Yamasaki, T.2
Nagano, K.3
Sugimoto, H.4
Shichijo, M.5
Gantner, F.6
Bacon, B.K.7
-
34
-
-
67649411644
-
Human arylacetamide deacetylase is a principal enzyme in flutamide hydrosis
-
doi: 10.1124/dmd.110.033720.
-
Watanabe A, Fukami T, Nakajima M, Takamiya M, Aoki Y, Yokoi T. 2010. Human arylacetamide deacetylase is a principal enzyme in flutamide hydrosis. Drug Metab. Dispos. 37: 1513-1520; doi: 10.1124/dmd.110.033720.
-
(2010)
Drug Metab. Dispos.
, vol.37
, pp. 1513-1520
-
-
Watanabe, A.1
Fukami, T.2
Nakajima, M.3
Takamiya, M.4
Aoki, Y.5
Yokoi, T.6
-
37
-
-
69449098657
-
Knockdown of superoxide disumutase 2 enhances acetaminophen-induced hepatotoxicity in rat
-
doi: 10.1016/j.tox.2009.07.017.
-
Yoshikawa Y, Morita M, Hosomi H, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. 2009a. Knockdown of superoxide disumutase 2 enhances acetaminophen-induced hepatotoxicity in rat. Toxicology 264: 89-95; doi: 10.1016/j.tox.2009.07.017.
-
(2009)
Toxicology
, vol.264
, pp. 89-95
-
-
Yoshikawa, Y.1
Morita, M.2
Hosomi, H.3
Tsuneyama, K.4
Fukami, T.5
Nakajima, M.6
Yokoi, T.7
-
38
-
-
68049090823
-
Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity
-
doi: 10.1016/j.tiv.2009.05.024.
-
Yoshikawa Y, Hosiomi H, Fukami T, Nakajima M, Yokoi T. 2009b. Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity. Toxicol. in Vitro 23: 1179-1187; doi: 10.1016/j.tiv.2009.05.024.
-
(2009)
Toxicol. in Vitro
, vol.23
, pp. 1179-1187
-
-
Yoshikawa, Y.1
Hosiomi, H.2
Fukami, T.3
Nakajima, M.4
Yokoi, T.5
|