메뉴 건너뛰기




Volumn 17, Issue 2, 2013, Pages 127-138

Targeting the fetal acetylcholine receptor in rhabdomyosarcoma

Author keywords

Acetylcholine receptor; Fetal; Immune therapy; Rhabdomyosarcoma

Indexed keywords

BACTERIAL TOXIN; FETAL NICOTINIC ACETYLCHOLINE RECEPTOR; IMMUNOTOXIN; NICOTINIC RECEPTOR; ONCOLYTIC VIRUS; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY 35 EXOTOXIN A; UNCLASSIFIED DRUG;

EID: 84872231618     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2013.734500     Document Type: Review
Times cited : (9)

References (120)
  • 1
    • 78649908527 scopus 로고    scopus 로고
    • Childhood rhabdomyosarcoma: New insight on biology and treatment
    • Huh W, Skapek S. Childhood rhabdomyosarcoma: new insight on biology and treatment. Curr Oncol Rep 2010;12:402-10
    • (2010) Curr Oncol Rep , vol.12 , pp. 402-410
    • Huh, W.1    Skapek, S.2
  • 2
    • 0036190224 scopus 로고    scopus 로고
    • Soft tissue sarcoma in children: Prognosis and management
    • Koscielniak E, Morgan M, Treuner J. Soft tissue sarcoma in children: Prognosis and management. Pediatric Drugs 2002; 4:21-8 (Pubitemid 34208343)
    • (2002) Pediatric Drugs , vol.4 , Issue.1 , pp. 21-28
    • Koscielniak, E.1    Morgan, M.2    Treuner, J.3
  • 3
    • 80052664254 scopus 로고    scopus 로고
    • Soft tissue sarcoma across the age spectrum: A population-based study from the surveillance epidemiology and end results database
    • Ferrari A, Sultan I, Huang TT, et al. Soft tissue sarcoma across the age spectrum: A population-based study from the surveillance epidemiology and end results database. Pediatr Blood Cancer 2011;57(6):943-9
    • (2011) Pediatr Blood Cancer , vol.57 , Issue.6 , pp. 943-949
    • Ferrari, A.1    Sultan, I.2    Huang, T.T.3
  • 6
    • 84857982296 scopus 로고    scopus 로고
    • AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell
    • Jothi M, Nishijo K, Keller C, Mal AK. AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell. Cell Cycle 2012;11:895-908
    • (2012) Cell Cycle , vol.11 , pp. 895-908
    • Jothi, M.1    Nishijo, K.2    Keller, C.3    Mal, A.K.4
  • 7
    • 84887212617 scopus 로고    scopus 로고
    • Integrated functions of pax3 and pax7 in the regulation of proliferation cell size and myogenic differentiation
    • Collins CA, Gnocchi VF, White RB et al. Integrated functions of pax3 and pax7 in the regulation of proliferation cell size and myogenic differentiation. PLoS One 2009;4:e4475
    • (2009) PLoS One , vol.4
    • Collins, C.A.1    Gnocchi, V.F.2    White, R.B.3
  • 8
    • 84873406407 scopus 로고    scopus 로고
    • Alveolar rhabdomyosarcomaassociated proteins pax3foxo1a and pax7foxo1a suppress the transcriptional activity of myod-target genes in muscle stem cells
    • Epub ahead of print]
    • Calhabeu F, Hayashi S, Morgan JE et al. Alveolar rhabdomyosarcomaassociated proteins PAX3/FOXO1A and PAX7/FOXO1A suppress the transcriptional activity of MyoD-target genes in muscle stem cells. Oncogene 2012; [Epub ahead of print]
    • (2012) Oncogene
    • Calhabeu, F.1    Hayashi, S.2    Morgan, J.E.3
  • 9
    • 0042121075 scopus 로고    scopus 로고
    • PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells
    • Tiffin N, Williams RD, Shipley J Pritchard-Jones K. PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells. Br J Cancer 89:327-32
    • Br J Cancer , vol.89 , pp. 327-332
    • Tiffin, N.1    Williams, R.D.2    Shipley, J.3    Pritchard-Jones, K.4
  • 10
    • 34548446433 scopus 로고    scopus 로고
    • Sarcomas: Genetics, signalling, and cellular origins. Part I: The fellowship of TET
    • DOI 10.1002/path.2209
    • Riggi N, Cironi L, Suva ML Stamenkovic I. Sarcomas: genetics signalling, and cellular origins. Part 1: The fellowship of TET. J Pathol 2007; 213:4-20 (Pubitemid 47354561)
    • (2007) Journal of Pathology , vol.213 , Issue.1 , pp. 4-20
    • Riggi, N.1    Cironi, L.2    Suva, M.-L.3    Stamenkovic, I.4
  • 11
    • 34249905193 scopus 로고    scopus 로고
    • Fishing for the origins of cancer
    • DOI 10.1101/gad.1563707
    • Merlino G, Khanna C. Fishing for the origins of cancer. Genes Dev 2007; 21:1275-9 (Pubitemid 46871031)
    • (2007) Genes and Development , vol.21 , Issue.11 , pp. 1275-1279
    • Merlino, G.1    Khanna, C.2
  • 13
    • 73349096624 scopus 로고    scopus 로고
    • Adult-type rhabdomyosarcoma: Analysis of 57 cases with clinicopathologic description identification of 3 morphologic patterns and prognosis
    • Stock NM, Chibon F, Nguyen Binh MB, et al. Adult-type rhabdomyosarcoma: Analysis of 57 cases with clinicopathologic description identification of 3 morphologic patterns and prognosis. Am J Surg Pathol 2009; 33:1850-9
    • (2009) Am J Surg Pathol , vol.33 , pp. 1850-1859
    • Stock, N.M.1    Chibon, F.2    Nguyen Binh, M.B.3
  • 14
    • 77954535843 scopus 로고    scopus 로고
    • Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity
    • Chibon F, Lagarde P, Salas S, et al. Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity. Nat Med 2010;16:781-7
    • (2010) Nat Med , vol.16 , pp. 781-787
    • Chibon, F.1    Lagarde, P.2    Salas, S.3
  • 16
    • 59649085853 scopus 로고    scopus 로고
    • Molecular classification of rhabdomyosarcoma-genotypic and phenotypic determinants of diagnosis: A report from the children's oncology group
    • Davicioni E, Anderson MJ, Finckenstein FG, et al. Molecular classification of rhabdomyosarcoma-genotypic and phenotypic determinants of diagnosis: A report from the children's oncology group. Am J Pathol 2009;174:550-64
    • (2009) Am J Pathol , vol.174 , pp. 550-564
    • Davicioni, E.1    Anderson, M.J.2    Finckenstein, F.G.3
  • 17
    • 2342475764 scopus 로고    scopus 로고
    • A novel t(2;20)(q35;p12) in embryonal rhabdomyosarcoma
    • DOI 10.1016/j.cancergencyto.2003.08.023, PII S016546080300390X
    • Ho RH, Johnson J, Dev VG, Whitlock JA. A novel t(2;20)(q35;p12) in embryonal rhabdomyosarcoma. Cancer Genet Cytogenet 2004;151:73-7 (Pubitemid 38569635)
    • (2004) Cancer Genetics and Cytogenetics , vol.151 , Issue.1 , pp. 73-77
    • Ho, R.H.1    Johnson, J.2    Dev, V.G.3    Whitlock, J.A.4
  • 18
    • 64649098780 scopus 로고    scopus 로고
    • Translocation (2;8)(q35;q13): A recurrent abnormality in congenital embryonal rhabdomyosarcoma
    • Meloni-Ehrig A, Smith B, Zgoda J, et al. Translocation (2;8)(q35;q13): A recurrent abnormality in congenital embryonal rhabdomyosarcoma. Cancer Genet Cytogenet 2009;191:43-5
    • (2009) Cancer Genet Cytogenet , vol.191 , pp. 43-5
    • Meloni-Ehrig, A.1    Smith, B.2    Zgoda, J.3
  • 19
    • 35748940315 scopus 로고    scopus 로고
    • Sanchez de Toledo Codina J. Molecular biology of rhabdomyosarcoma
    • Gallego Melcon S, Sanchez de Toledo Codina J. Molecular biology of rhabdomyosarcoma. Clin Transl Oncol 2007;9:415-19
    • (2007) Clin Transl Oncol , vol.9 , pp. 415-419
    • Gallego Melcon, S.1
  • 20
    • 83655182970 scopus 로고    scopus 로고
    • A set of imprinted genes required for normal body growth also promotes growth of rhabdomyosarcoma cells
    • Rezvani G, Lui JCK, Barnes KM, Baron J. A set of imprinted genes required for normal body growth also promotes growth of rhabdomyosarcoma cells. Pediatr Res 2012;71:32-8
    • (2012) Pediatr Res , vol.71 , pp. 32-8
    • Rezvani, G.1    Lui, J.C.K.2    Barnes, K.M.3    Baron, J.4
  • 21
    • 0033205985 scopus 로고    scopus 로고
    • Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma
    • Anderson J, Gordon A, McManus A et al. Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma. Neoplasia 1999;1:340-8
    • (1999) Neoplasia , vol.1 , pp. 340-348
    • Anderson, J.1    Gordon, A.2    McManus, A.3
  • 23
    • 84860335527 scopus 로고    scopus 로고
    • Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions
    • Olguin HC, Pisconti A. Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions. J Cell Mol Med 2012;16:1013-25
    • (2012) J Cell Mol Med , vol.16 , pp. 1013-1025
    • Olguin, H.C.1    Pisconti, A.2
  • 25
    • 0034853327 scopus 로고    scopus 로고
    • PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma
    • Anderson J, Ramsay A, Gould S Pritchard-Jones K. PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma. Am J pathol 2001; 159:1089-96 (Pubitemid 32847199)
    • (2001) American Journal of Pathology , vol.159 , Issue.3 , pp. 1089-1096
    • Anderson, J.1    Ramsay, A.2    Gould, S.3    Pritchard-Jones, K.4
  • 26
    • 68549135290 scopus 로고    scopus 로고
    • Integrated data from 2 randomized double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
    • Higano CS, Schellhammer PF, Small EJ et al. Integrated data from 2 randomized double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 2009;115:3670-9
    • (2009) Cancer , vol.115 , pp. 3670-3679
    • Higano, C.S.1    Schellhammer, P.F.2    Small, E.J.3
  • 27
    • 73349113524 scopus 로고    scopus 로고
    • Endplate destruction due to maternal antibodies in arthrogryposis multiplex congenita
    • Reimann J, Jacobson L, Vincent A Kornblum C. Endplate destruction due to maternal antibodies in arthrogryposis multiplex congenita. Neurology 2009; 73:1806-8
    • (2009) Neurology , vol.73 , pp. 1806-1808
    • Reimann, J.1    Jacobson, L.2    Vincent, A.3    Kornblum, C.4
  • 28
    • 16544387908 scopus 로고    scopus 로고
    • European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: Final results and analysis of prognostic factors
    • Carli M, Colombatti R, Oberlin O, et al. European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: final results and analysis of prognostic factors. J Clin Oncol 2004;22:4787-94
    • (2004) J Clin Oncol , vol.22 , pp. 4787-4794
    • Carli, M.1    Colombatti, R.2    Oberlin, O.3
  • 31
    • 36749055719 scopus 로고    scopus 로고
    • Optimal management strategies for rhabdomyosarcoma in children
    • DOI 10.2165/00148581-200709060-00006
    • Walterhouse D, Watson A. Optimal management strategies for rhabdomyosarcoma in children. Pediatric Drugs 2007;9:391-400 (Pubitemid 350208913)
    • (2007) Pediatric Drugs , vol.9 , Issue.6 , pp. 391-400
    • Walterhouse, D.1    Watson, A.2
  • 32
    • 4644335909 scopus 로고    scopus 로고
    • Cyclophosphamide dose intensification during induction therapy for intermediate-risk pediatric rhabdomyosarcoma is feasible but does not improve outcome
    • Spunt SL, Smith LM, Ruymann FB et al. cyclophosphamide dose intensification during induction therapy for intermediate-risk pediatric rhabdomyosarcoma is feasible but does not improve outcome. Clin Cancer Res 2004;10:6072-9
    • (2004) Clin Cancer Res , vol.10 , pp. 6072-6079
    • Spunt, S.L.1    Smith, L.M.2    Ruymann, F.B.3
  • 33
    • 18744413524 scopus 로고    scopus 로고
    • Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma a report from the intergroup rhabdomyosarcoma study iv
    • Breneman JC, Lyden E, Pappo AS, et al. Prognostic Factors and Clinical Outcomes in Children and Adolescents With Metastatic Rhabdomyosarcoma-A Report From the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol 2003;21:78-84
    • (2003) J Clin Oncol , vol.21 , pp. 78-84
    • Breneman, J.C.1    Lyden, E.2    Pappo, A.S.3
  • 35
    • 27644482033 scopus 로고    scopus 로고
    • Poor outcome of two children with relapsed state stage IV alveolar rhabdomyosarcoma after allogeneic stem cell transplantation
    • DOI 10.1080/08880010500278806
    • Doelken R, Weigel S, Schueler F, et al. Poor outcome of two children with relapsed state stage IV alveolar rhabdomyosarcoma after allogeneic stem cell transplantation. Pediatr Hematol Oncol 2005;22:699-703 (Pubitemid 41572165)
    • (2005) Pediatric Hematology and Oncology , vol.22 , Issue.8 , pp. 699-703
    • Doelken, R.1    Weigel, S.2    Schueler, F.3    Doelken, G.4    Beck, J.F.5
  • 36
    • 0033224439 scopus 로고    scopus 로고
    • A comparison of MyoD1 and fetal acetylcholine receptor expression in childhood tumors and normal tissues: Implications for the molecular diagnosis of minimal disease in rhabdomyosarcomas
    • Gattenloehner S, Dockhorn-Dworniczak B, Leuschner I, et al. A Comparison of MyoD1 and fetal acetylcholine receptor expression in childhood tumors and normal tissues implications for the molecular diagnosis of minimal disease in rhabdomyosarcomas. J Mol Diagn 1999;1:23-31 (Pubitemid 129693358)
    • (1999) Journal of Molecular Diagnostics , vol.1 , Issue.1 , pp. 23-31
    • Gattenloehner, S.1    Dockhorn-Dworniczak, B.2    Leuschner, I.3    Vincent, A.4    Muller-Hermelink, H.-K.5    Marx, A.6
  • 37
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: from structure to function
    • Albuquerque E, Pereira E, Alkondon M Scott W. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol Rev 2009;89:73-120
    • (2009) Physiol Rev , vol.89 , pp. 73-120
    • Albuquerque, E.1    Pereira, E.2    Alkondon, M.3    Scott, W.4
  • 38
    • 84856343171 scopus 로고    scopus 로고
    • Current status of the congenital myasthenic syndromes
    • Engel AG. Current status of the congenital myasthenic syndromes. Neuromuscul Disord 2012;22:99-111
    • (2012) Neuromuscul Disord , vol.22 , pp. 99-111
    • Engel, A.G.1
  • 41
    • 0028314759 scopus 로고
    • Response to human acetylcholine receptor alpha138-199: Determinant spreading initiates autoimmunity to self-antigen in rabbits
    • DOI 10.1016/0165-2478(94)90168-6
    • Vincent A, Jacobson L, Shillito P. Response to human acetylcholine receptor alpha138-199: Determinant spreading initiates autoimmunity to self-antigen in rabbits. Immunol Lett 1994;39:269-75 (Pubitemid 24123977)
    • (1994) Immunology Letters , vol.39 , Issue.3 , pp. 269-275
    • Vincent, A.1    Jacobson, L.2    Shillito, P.3
  • 42
    • 0025582538 scopus 로고
    • Effect of reinnervation on the degradation rate of junctional acetylcholine receptors synthesized in denervated skeletal muscles
    • Shyng S, Salpeter M. Effect of reinnervation on the degradation rate of junctional acetylcholine receptors synthesized in denervated skeletal muscles. J Neurosci 1990;10:3905-15
    • (1990) J Neurosci , vol.10 , pp. 3905-3915
    • Shyng, S.1    Salpeter, M.2
  • 43
    • 0035511932 scopus 로고    scopus 로고
    • Induction, assembly, maturation and maintenance of a postsynaptic apparatus
    • DOI 10.1038/35097557
    • Sanes JR, Lichtman JW. Induction assembly, maturation and maintenance of a postsynaptic apparatus. Nat Rev Neurosci 2001;2:791-805 (Pubitemid 33674061)
    • (2001) Nature Reviews Neuroscience , vol.2 , Issue.11 , pp. 791-805
    • Sanes, J.R.1    Lichtman, J.W.2
  • 44
    • 0141859737 scopus 로고    scopus 로고
    • Neurophysiology of the neuromuscular junction: Overview
    • DOI 10.1196/annals.1254.002
    • Ruff RL. Neurophysiology of the neuromuscular junction: overview. Ann NY Acad Sci 2003;998:1-10 (Pubitemid 37194141)
    • (2003) Annals of the New York Academy of Sciences , vol.998 , pp. 1-10
    • Ruff, R.L.1
  • 45
    • 0002268069 scopus 로고
    • On the permeability of end-plate membrane during the action of transmitter
    • Takeuchi A, Takeuchi N. On the permeability of end-plate membrane during the action of transmitter. J Physiol 1960;154:52-67
    • (1960) J Physiol , vol.154 , pp. 52-67
    • Takeuchi, A.1    Takeuchi, N.2
  • 47
    • 77955877122 scopus 로고    scopus 로고
    • Thymoma and paraneoplastic myasthenia gravis
    • Marx A, Willcox N, Leite M, et al. Thymoma and paraneoplastic myasthenia gravis. Autoimmunity 2010;43:413-27
    • (2010) Autoimmunity , vol.43 , pp. 413-427
    • Marx, A.1    Willcox, N.2    Leite, M.3
  • 48
    • 80051660037 scopus 로고    scopus 로고
    • Case of rhabdomyosarcoma presenting with myasthenia gravis
    • Mehmood QU, Shaktawat SS, Parikh O. Case of rhabdomyosarcoma presenting with myasthenia gravis. J Clin Oncol 2011;29:e653-5
    • (2011) J Clin Oncol , vol.29
    • Mehmood, Q.U.1    Shaktawat, S.S.2    Parikh, O.3
  • 49
    • 33749145156 scopus 로고    scopus 로고
    • Identification of acetylcholine receptor subunits differentially expressed in singly and multiply innervated fibers of extraocular muscles
    • DOI 10.1167/iovs.06-0073
    • Fraterman S, Khurana TS, Rubinstein NA. Identification of acetylcholine receptor subunits differentially expressed in singly and multiply innervated fibers of extraocular muscles. Invest Ophthalmol Vis Sci 2006;47:3828-34 (Pubitemid 46044297)
    • (2006) Investigative Ophthalmology and Visual Science , vol.47 , Issue.9 , pp. 3828-3834
    • Fraterman, S.1    Khurana, T.S.2    Rubinstein, N.A.3
  • 51
    • 79955940627 scopus 로고    scopus 로고
    • CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres
    • Walter D, Satheesha S, Albrecht P, et al. CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres. PLoS One 2011;6:e19506
    • (2011) PLoS One , vol.6
    • Walter, D.1    Satheesha, S.2    Albrecht, P.3
  • 52
    • 71649083910 scopus 로고    scopus 로고
    • Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells
    • Hirotsu M, Setoguchi T, Matsunoshita Y, et al. Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells. Br J Cancer 2009;101:2030-7
    • (2009) Br J Cancer , vol.101 , pp. 2030-2037
    • Hirotsu, M.1    Setoguchi, T.2    Matsunoshita, Y.3
  • 55
    • 79952159610 scopus 로고    scopus 로고
    • Many routes to the same destination: Lessons from skeletal muscle development
    • Mok GF, Sweetman D. Many routes to the same destination: lessons from skeletal muscle development. Reproduction 2011;141:301-12
    • (2011) Reproduction , vol.141 , pp. 301-312
    • Mok, G.F.1    Sweetman, D.2
  • 56
    • 0347519180 scopus 로고    scopus 로고
    • Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation
    • DOI 10.1242/dev.00834
    • Dahlqvist C, Blokzijl A, Chapman G et al. Functional notch signaling is required for BMP4-induced inhibition of myogenic differentiation. Development 2003;130:6089-99 (Pubitemid 38008810)
    • (2003) Development , vol.130 , Issue.24 , pp. 6089-6099
    • Dahlqvist, C.1    Blokzijl, A.2    Chapman, G.3    Falk, A.4    Dannaeus, K.5    Ibanez, C.F.6    Lendahl, U.7
  • 57
    • 0025789857 scopus 로고
    • Multiple binding sites for myogenic regulatory factors are required for expression of the acetylcholine receptor gamma-subunit gene
    • Gilmour BP, Fanger GR, Newton C et al. Multiple binding sites for myogenic regulatory factors are required for expression of the acetylcholine receptor gamma-subunit gene. J Biol Chem 1991;266:19871-4 (Pubitemid 21908397)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.30 , pp. 19871-19874
    • Gilmour, B.P.1    Fanger, G.R.2    Newton, C.3    Evans, S.M.4    Gardner, P.D.5
  • 58
    • 0027420568 scopus 로고
    • Cell type- and differentiation-dependent expression from the mouse acetylcholine receptor alpha-subunit promoter
    • Sunyer T, Merlie JP. Cell type- and differentiation-dependent expression from the mouse acetylcholine receptor alpha-subunit promoter. J Neurosci Res 1993;36:224-34 (Pubitemid 23294151)
    • (1993) Journal of Neuroscience Research , vol.36 , Issue.2 , pp. 224-234
    • Sunyer, T.1    Merlie, J.P.2
  • 59
    • 0027963583 scopus 로고
    • Characterization of the functional role of E-box elements for the transcriptional activity of rat acetylcholine receptor alpha-subunit and gamma-subunit gene promoters in primary muscle cell cultures
    • Durr I, Numberger M, Berberich C Witzemann V. Characterization of the functional role of e-box elements for the transcriptional activity of rat acetylcholine receptor epsilon-subunit and gamma-subunit gene promoters in primary muscle cell cultures. Eur J Biochem 1994;224:353-64 (Pubitemid 24282816)
    • (1994) European Journal of Biochemistry , vol.224 , Issue.2 , pp. 353-364
    • Durr, I.1    Numberger, M.2    Berberich, C.3    Witzemann, V.4
  • 60
    • 80053173557 scopus 로고    scopus 로고
    • MicroRNAs in rhabdomyosarcoma: Pathogenetic implications and translational potentiality
    • Rota R, Ciarapica R, Giordano A, et al. MicroRNAs in rhabdomyosarcoma: Pathogenetic implications and translational potentiality. Mol Cancer 2011;10:120
    • (2011) Mol Cancer , vol.10 , pp. 120
    • Rota, R.1    Ciarapica, R.2    Giordano, A.3
  • 62
    • 9144229330 scopus 로고    scopus 로고
    • Regulation of nicotinic receptor expression by the ubiquitin-proteasome system
    • DOI 10.1038/sj.emboj.7600436
    • Christianson JC, Green WN. Regulation of nicotinic receptor expression by the ubiquitin-proteasome system. EMBO J 2004;23:4156-65 (Pubitemid 39546154)
    • (2004) EMBO Journal , vol.23 , Issue.21 , pp. 4156-4165
    • Christianson, J.C.1    Green, W.N.2
  • 64
    • 84872239449 scopus 로고    scopus 로고
    • Variable resistance of RMS to INFgamma signaling
    • Simon-Keller K, Mo-inger K, Bohlender A-L, et al. Variable resistance of RMS to INFgamma signaling. ISRN Oncol 2012;2012:789152
    • (2012) ISRN Oncol , vol.2012 , pp. 789152
    • Simon-Keller, K.1    Moinger, K.2    Bohlender, A.-L.3
  • 66
    • 0035973305 scopus 로고    scopus 로고
    • Myasthenia gravis
    • DOI 10.1016/S0140-6736(00)05186-2
    • Vincent A, Palace J, Hilton-Jones D. Myasthenia gravis. Lancet 2001; 357:2122-8 (Pubitemid 32607461)
    • (2001) Lancet , vol.357 , Issue.9274 , pp. 2122-2128
    • Vincent, A.1    Palace, J.2    Hilton-Jones, D.3
  • 67
    • 0028779203 scopus 로고
    • Myasthenia gravis
    • Drachman DB. Myasthenia Gravis. N Engl J Med 1994;330:1797-810
    • (1994) N Engl J Med , vol.330 , pp. 1797-1810
    • Drachman, D.B.1
  • 68
    • 84872233562 scopus 로고    scopus 로고
    • In: Engel AG, editor. Myasthenia gravis and Myasthenic disorders. Oxford University Press New York:
    • Hohlfeld R, Wekerle H, Marx A. The immunopathogenesis of myasthenia gravis. In: Engel AG, editor. Myasthenia gravis and Myasthenic disorders. Oxford University Press; New York: 2012. p. 60-89
    • (2012) The immunopathogenesis of myasthenia gravis , pp. 60-89
    • Hohlfeld, R.1    Wekerle, H.2    Marx, A.3
  • 70
    • 77957550860 scopus 로고    scopus 로고
    • The autoimmune regulator AIRE in thymoma biology: Autoimmunity and beyond
    • Marx A, Hohenberger P, Hoffmann H et al. The autoimmune regulator AIRE in thymoma biology: Autoimmunity and beyond. J Thorac Oncol 2010;5:S266-72
    • (2010) J Thorac Oncol , vol.5
    • Marx, A.1    Hohenberger, P.2    Hoffmann, H.3
  • 74
    • 49849097621 scopus 로고    scopus 로고
    • Antigen-specific apheresis of human anti-acetylcholine receptor autoantibodies from myasthenia gravis patients' sera using Escherichia coli-expressed receptor domains
    • Zisimopoulou P, Lagoumintzis G, Poulas K, Tzartos SJ. Antigen-specific apheresis of human anti-acetylcholine receptor autoantibodies from myasthenia gravis patients' sera using Escherichia coli-expressed receptor domains. J Neuroimmunol 2008;200:133-41
    • (2008) J Neuroimmunol , vol.200 , pp. 133-141
    • Zisimopoulou, P.1    Lagoumintzis, G.2    Poulas, K.3    Tzartos, S.J.4
  • 76
    • 0029067153 scopus 로고
    • Arthrogryposis multiplex congenita with maternal autoantibodies specific for a fetal antigen
    • Vincent A, Newland C, Beeson D, et al. Arthrogryposis multiplex congenita with maternal autoantibodies specific for a fetal antigen. Lancet 1995;346:24-5
    • (1995) Lancet , vol.346 , pp. 24-5
    • Vincent, A.1    Newland, C.2    Beeson, D.3
  • 77
    • 0036594594 scopus 로고    scopus 로고
    • Review: Epitope spreading in systemic lupus erythematosus: Identification of triggering peptide sequences
    • DOI 10.1002/art.10263
    • Monneaux F, Muller S. Epitope spreading in systemic lupus erythematosus: identification of triggering peptide sequences. Arthritis Rheum 2002;46:1430-8 (Pubitemid 34620187)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.6 , pp. 1430-1438
    • Monneaux, F.1    Muller, S.2
  • 79
    • 51649128231 scopus 로고    scopus 로고
    • Preferential expression of AChR epsilon-subunit in thymomas from patients with myasthenia gravis
    • MacLennan CA, Vincent A, Marx A et al. Preferential expression of AChR epsilon-subunit in thymomas from patients with myasthenia gravis. J Neuroimmunol 2008;201:28-32
    • (2008) J Neuroimmunol , vol.201 , pp. 28-32
    • MacLennan, C.A.1    Vincent, A.2    Marx, A.3
  • 80
    • 0035795092 scopus 로고    scopus 로고
    • Presentation by myoblasts of an epitope from endogenous acetylcholine receptor indicates a potential role in the spreading of the immune response
    • DOI 10.1016/S0165-5728(01)00272-7, PII S0165572801002727
    • Curnow J, Corlett L, Willcox N, Vincent A. Presentation by myoblasts of an epitope from endogenous acetylcholine receptor indicates a potential role in the spreading of the immune response. J Neuroimmunol 2001;115:127-34 (Pubitemid 32245660)
    • (2001) Journal of Neuroimmunology , vol.115 , Issue.1-2 , pp. 127-134
    • Curnow, J.1    Corlett, L.2    Willcox, N.3    Vincent, A.4
  • 81
    • 0033043998 scopus 로고    scopus 로고
    • Early-onset myasthenia gravis: A recurring T-cell epitope in the adult- specific acetylcholine receptor alpha subunit presented by the susceptibility allele HLA-DR52a
    • DOI 10.1002/1531-8249(199902)45:2<224::AID-ANA13>3.0.CO;2-B
    • Hill M, Beeson D, Moss P, et al. Early-onset myasthenia gravis: A recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a. Ann Neurol 1999;45:224-31 (Pubitemid 29072369)
    • (1999) Annals of Neurology , vol.45 , Issue.2 , pp. 224-231
    • Hill, M.1    Beeson, D.2    Moss, P.3    Jacobson, L.4    Bond, A.5    Corlett, L.6    Newsom-Davis, J.7    Vincent, A.8    Willcox, N.9
  • 83
    • 53749099358 scopus 로고    scopus 로고
    • Strategies to overcome obstacles to successful immunotherapy of melanoma
    • Pandolfi F, Cianci R, Lolli S, et al. Strategies to overcome obstacles to successful immunotherapy of melanoma. Int J Immunopathol Pharmacol 2008;21:493-500
    • (2008) Int J Immunopathol Pharmacol , vol.21 , pp. 493-500
    • Pandolfi, F.1    Cianci, R.2    Lolli, S.3
  • 84
    • 79251586236 scopus 로고    scopus 로고
    • Gene carriers and transfection systems used in the recombination of dendritic cells for effective cancer immunotherapy
    • Chen Y-Z, Yao X-L, Tabata Y, et al. Gene carriers and transfection systems used in the recombination of dendritic cells for effective cancer immunotherapy. Clin Dev Immunol 2008;62:565643
    • (2008) Clin Dev Immunol , vol.62 , pp. 565643
    • Chen, Y.-Z.1    Yao, X.-L.2    Tabata, Y.3
  • 85
    • 63149171153 scopus 로고    scopus 로고
    • Immunogenicity and antitumor effects of vaccination with peptide vaccine +/-granulocyte-monocyte colony-stimulating factor and/or IFN-alpha2b in advanced metastatic melanoma: Eastern cooperative oncology group phase II trial E1696
    • Kirkwood JM, Lee S, Moschos SJ, et al. Immunogenicity and antitumor effects of vaccination with peptide vaccine +/-granulocyte-monocyte colony-stimulating factor and/or IFN-alpha2b in advanced metastatic melanoma: Eastern cooperative oncology group phase II trial E1696. Clin Cancer Res 2009;15:1443-51
    • (2009) Clin Cancer Res , vol.15 , pp. 1443-1451
    • Kirkwood, J.M.1    Lee, S.2    Moschos, S.J.3
  • 86
    • 77955104115 scopus 로고    scopus 로고
    • WT1 peptide immunotherapy for cancer in children and young adults
    • Hashii Y, Sato E, Ohta H, et al. WT1 peptide immunotherapy for cancer in children and young adults. Pediatr Blood Cancer 2010;55:352-5
    • (2010) Pediatr Blood Cancer , vol.55 , pp. 352-355
    • Hashii, Y.1    Sato, E.2    Ohta, H.3
  • 87
    • 51049105734 scopus 로고    scopus 로고
    • A Pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas
    • Mackall CL, Rhee EH, Read EJ, et al. A Pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas. Clin Cancer Res 2008;14:4850-8
    • (2008) Clin Cancer Res , vol.14 , pp. 4850-4858
    • Mackall, C.L.1    Rhee, E.H.2    Read, E.J.3
  • 88
    • 80052686056 scopus 로고    scopus 로고
    • Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy
    • Meadors JL, Cui Y, Chen Q-R, et al. Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy. Pediat Blood Cancer 2011;57:921-9
    • (2011) Pediat Blood Cancer , vol.57 , pp. 921-929
    • Meadors, J.L.1    Cui, Y.2    Chen, Q.-R.3
  • 89
    • 74349084455 scopus 로고    scopus 로고
    • Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells
    • Wrzesinski C, Paulos CM, Kaiser A et al. increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells. J Immunother 2010;33:1-7
    • (2010) J Immunother , vol.33 , pp. 1-7
    • Wrzesinski, C.1    Paulos, C.M.2    Kaiser, A.3
  • 90
    • 81955160713 scopus 로고    scopus 로고
    • Antibody drug conjugates-Trojan horses in the war on cancer
    • Iyer U, Kadambi VJ. Antibody drug conjugates-Trojan horses in the war on cancer. J Pharmacol Toxicol Methods 2011;64:207-12
    • (2011) J Pharmacol Toxicol Methods , vol.64 , pp. 207-212
    • Iyer, U.1    Kadambi, V.J.2
  • 91
    • 79955104910 scopus 로고    scopus 로고
    • Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases
    • Lorberboum-Galski H. Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases. Expert Opin Drug Deliv 2011;8:605-21
    • (2011) Expert Opin Drug Deliv , vol.8 , pp. 605-621
    • Lorberboum-Galski, H.1
  • 92
    • 79957484300 scopus 로고    scopus 로고
    • Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737
    • Fitzgerald DJ, Moskatel E, Ben-josef G et al. Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737. Leuk Lymphoma 2011;52:79-81
    • (2011) Leuk Lymphoma , vol.52 , pp. 79-81
    • Fitzgerald, D.J.1    Moskatel, E.2    Ben-josef, G.3
  • 94
    • 67650678448 scopus 로고    scopus 로고
    • Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy
    • Litvak-Greenfeld D, Benhar I. Risks and untoward toxicities of antibody-based immunoconjugates. Adv Drug Delivery Rev 94. Mathew M, Verma RS. Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy. Cancer Sci 2009;100:1359-65
    • (2009) Cancer Sci , vol.100 , pp. 1359-1365
    • Mathew, M.1    Verma, R.S.2
  • 96
    • 0034659745 scopus 로고    scopus 로고
    • Ki-4(scFv)-ETA', a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated hodgkin tumors in SCID mice
    • Barth S, Huhn M, Matthey B, et al. Ki-4(scFv)-ETA¢, a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice. Blood 2000;95:3909-14 (Pubitemid 30412867)
    • (2000) Blood , vol.95 , Issue.12 , pp. 3909-3914
    • Barth, S.1    Huhn, M.2    Matthey, B.3    Tawadros, S.4    Schnell, R.5    Schinkothe, T.6    Diehl, V.7    Engert, A.8
  • 97
    • 84858645667 scopus 로고    scopus 로고
    • A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model
    • Gattenlohner S, Jori-en H, Huhn M et al. A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model. J Biomed Biotechnol 2010;2010:187621
    • (2010) J Biomed Biotechnol
    • Gattenlohner, S.1    Jorien, H.2    Huhn, M.3
  • 98
    • 80054118081 scopus 로고    scopus 로고
    • Antibody fusion proteins: Anti-CD22 recombinant immunotoxin moxetumomab pasudotox
    • Kreitman RJ, Pastan I. Antibody fusion proteins: Anti-CD22 recombinant immunotoxin moxetumomab pasudotox. Clin Cancer Res 2011;17:6398-405
    • (2011) Clin Cancer Res , vol.17 , pp. 6398-6405
    • Kreitman, R.J.1    Pastan, I.2
  • 99
    • 79955007493 scopus 로고    scopus 로고
    • Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes
    • Onda M, Beers R, Xiang L, et al. Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes. Proc Natl Acad Sci 2011. 108: 5742-5747
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 5742-5747
    • Onda, M.1    Beers, R.2    Xiang, L.3
  • 100
    • 84864068407 scopus 로고    scopus 로고
    • Therapeutic targets and recent advances in protein immunotoxins
    • Madhumathi J, Verma RS. Therapeutic targets and recent advances in protein immunotoxins. Curr Opin Microbiol. 2011;17(3):300-9
    • (2011) Curr Opin Microbiol. , vol.17 , Issue.3 , pp. 300-309
    • Madhumathi, J.1    Verma, R.S.2
  • 101
    • 0028879071 scopus 로고
    • A spacer region between the single chain antibody and the CD3zeta chain domain of chimeric T cell receptor components is required for efficient ligand binding and signaling activity
    • Moritz D, Groner B. A spacer region between the single chain antibody and the CD3zeta chain domain of chimeric T cell receptor components is required for efficient ligand binding and signaling activity. Gene Ther 1995;2:539-46
    • (1995) Gene Ther , vol.2 , pp. 539-546
    • Moritz, D.1    Groner, B.2
  • 102
    • 79960379942 scopus 로고    scopus 로고
    • Cytotoxic immunotherapy strategies for cancer: Mechanisms and clinical development
    • Aguilar LK, Guzik BW, Aguilar-Cordova E. Cytotoxic immunotherapy strategies for cancer: mechanisms and clinical development. J Cell Biochem 2011;112:1969-77
    • (2011) J Cell Biochem , vol.112 , pp. 1969-1977
    • Aguilar, L.K.1    Guzik, B.W.2    Aguilar-Cordova, E.3
  • 103
    • 0024327899 scopus 로고
    • Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
    • Mueller DL, Jenkins MK, Schwartz RH. Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol 1989;7:445-80 (Pubitemid 19138020)
    • (1989) Annual Review of Immunology , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 104
    • 0035576250 scopus 로고    scopus 로고
    • Tumor-specific T cell activation by recombinant immunoreceptors: CD3{zeta} signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3{zeta} signaling receptor molecule
    • Hombach A, Wieczarkowiecz A Marquardt T, et al. Tumor-Specific T Cell Activation by recombinant immunoreceptors: CD3{zeta} Signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3{zeta} signaling receptor molecule. J Immunol 2001;167:6123-31 (Pubitemid 33081538)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6123-6131
    • Hombach, A.1    Wieczarkowiecz, A.2    Marquardt, T.3    Heuser, C.4    Usai, L.5    Pohl, C.6    Seliger, B.7    Abken, H.8
  • 106
    • 78650967548 scopus 로고    scopus 로고
    • CD28 cosignalling does not affect the activation threshold in a chimeric antigen receptor-redirected T-cell attack
    • Chmielewski M, Hombach AA, Abken H. CD28 cosignalling does not affect the activation threshold in a chimeric antigen receptor-redirected T-cell attack. Gene Ther 2011;18:62-72
    • (2011) Gene Ther , vol.18 , pp. 62-72
    • Chmielewski, M.1    Hombach, A.A.2    Abken, H.3
  • 107
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer JN, Dudley ME, Feldman SA, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2011;19(12):2709-20
    • (2011) Blood , vol.19 , Issue.12 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3
  • 108
    • 77956629390 scopus 로고    scopus 로고
    • Adoptive immunotherapy for B cell malignancies with autologous chimeric antigen receptor modified tumor targeted T cells
    • Park JH, Brentjens RJ. Adoptive immunotherapy for B cell malignancies with autologous chimeric antigen receptor modified tumor targeted T cells. Discov Med 2010;9:277-88
    • (2010) Discov Med , vol.9 , pp. 277-288
    • Park, J.H.1    Brentjens, R.J.2
  • 109
    • 77952421566 scopus 로고    scopus 로고
    • Cytotoxic T cells transduced with chimeric anti-CD19 receptors prevent engraftment of primary lymphoblastic leukemia in vivo
    • Landmeier S, Altvater B, Pscherer S et al. Cytotoxic T cells transduced with chimeric anti-CD19 receptors prevent engraftment of primary lymphoblastic leukemia in vivo. Leukemia 2010;24:1080-4
    • (2010) Leukemia , vol.24 , pp. 1080-1084
    • Landmeier, S.1    Altvater, B.2    Pscherer, S.3
  • 110
    • 79953219131 scopus 로고    scopus 로고
    • Adoptive T-zell-therapie des rhabdomyosarkoms
    • Simon-Keller K, Paschen A, Eichmuller S, et al. Adoptive T-zell-therapie des rhabdomyosarkoms. Pathologe 2010;31:215-20
    • (2010) Pathologe , vol.31 , pp. 215-220
    • Simon-Keller, K.1    Paschen, A.2    Eichmuller, S.3
  • 111
    • 77957723967 scopus 로고    scopus 로고
    • Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
    • Fourcade J, Sun Z, Benallaoua M, et al. Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exper Med 2010;207:2175-86
    • (2010) J Exper Med , vol.207 , pp. 2175-2186
    • Fourcade, J.1    Sun, Z.2    Benallaoua, M.3
  • 112
    • 33751195938 scopus 로고    scopus 로고
    • XIAP targeting sensitizes Hodgkin lymphoma cells for cytolytic T-cell attack
    • Kashkar H, Seeger J-M, Hombach A et al. XIAP targeting sensitizes Hodgkin lymphoma cells for cytolytic T-cell attack. Blood 2006;108:3434-40
    • (2006) Blood , vol.108 , pp. 3434-3440
    • Kashkar, H.1    Seeger, J.-M.2    Hombach, A.3
  • 114
    • 77953311757 scopus 로고    scopus 로고
    • Cleavage of survivin by ganzyme M triggers degradation of the survivin-X-linked Inhibitor of Apoptosis Protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells
    • Hu D, Liu S, Shi L, et al. Cleavage of survivin by ganzyme M triggers degradation of the survivin-X-linked Inhibitor of Apoptosis Protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells. J Biol Chem 2010;285:18326-35
    • (2010) J Biol Chem , vol.285 , pp. 18326-18335
    • Hu, D.1    Liu, S.2    Shi, L.3
  • 115
    • 77956680686 scopus 로고    scopus 로고
    • Survivin and IAP proteins in cell-death mechanisms
    • Altieri D. Survivin and IAP proteins in cell-death mechanisms. Biochem J 2010;430:199-205
    • (2010) Biochem J , vol.430 , pp. 199-205
    • Altieri, D.1
  • 116
    • 85027956453 scopus 로고    scopus 로고
    • Thunder and lightning: Immunotherapy and oncolytic viruses collide
    • Melcher A, Parato K, Rooney CM, Bell JC. Thunder and lightning: immunotherapy and oncolytic viruses collide. Mol Ther 2011;19:1008-16
    • (2011) Mol Ther , vol.19 , pp. 1008-1016
    • Melcher, A.1    Parato, K.2    Rooney, C.M.3    Bell, J.C.4
  • 117
    • 45449114994 scopus 로고    scopus 로고
    • Reprogrammed viruses as cancer therapeutics: Targeted, armed and shielded
    • DOI 10.1038/nrmicro1927, PII NRMICRO1927
    • Cattaneo R, Miest T, Shashkova EV Barry MA. Reprogrammed viruses as cancer therapeutics: Targeted, armed and shielded. Nat Rev Micro 2008;6:529-40 (Pubitemid 351850977)
    • (2008) Nature Reviews Microbiology , vol.6 , Issue.7 , pp. 529-540
    • Cattaneo, R.1    Miest, T.2    Shashkova, E.V.3    Barry, M.A.4
  • 119
    • 80055056242 scopus 로고    scopus 로고
    • Uncommitted precursor cells might contribute to increased incidence of embryonal rhabdomyosarcoma in heterozygous Patched1-mutant mice
    • Nitzki F, Zibat A, Frommhold A, et al. Uncommitted precursor cells might contribute to increased incidence of embryonal rhabdomyosarcoma in heterozygous Patched1-mutant mice. Oncogene 2011;30:4428-36
    • (2011) Oncogene , vol.30 , pp. 4428-4436
    • Nitzki, F.1    Zibat, A.2    Frommhold, A.3
  • 120
    • 80052572908 scopus 로고    scopus 로고
    • The improvement of an anti-CD22 immunotoxin: Conversion to single-chain and disulfide stabilized form and affinity maturation by alanine scan
    • Kawa S, Onda M, Ho M, et al. The improvement of an anti-CD22 immunotoxin: Conversion to single-chain and disulfide stabilized form and affinity maturation by alanine scan. MABs 2011;3:479-86
    • (2011) MABs , vol.3 , pp. 479-486
    • Kawa, S.1    Onda, M.2    Ho, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.