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Volumn 52, Issue SUPPL. 2, 2011, Pages 79-81

Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737

Author keywords

ABT 737; apoptosis; BH3 only; Pseudomonas exotoxin

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; CASPASE 3; IMMUNOTOXIN; IMMUNOTOXIN BH3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; UNCLASSIFIED DRUG;

EID: 79957484300     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.569961     Document Type: Article
Times cited : (17)

References (7)
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    • Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1
    • Du X, Youle RJ, FitzGerald DJ, Pastan I. Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1. Mol Cell Biol 2010;30: 3444-3452.
    • (2010) Mol Cell Biol , vol.30 , pp. 3444-3452
    • Du, X.1    Youle, R.J.2    Fitzgerald, D.J.3    Pastan, I.4
  • 3
    • 6344289534 scopus 로고    scopus 로고
    • Downregulation of the antiapoptotic Mcl-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin
    • DOI 10.1002/ijc.20371
    • Andersson Y, Juell S, Fodstad Ø. Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin. Int J Cancer 2004;112:475-483. (Pubitemid 39390614)
    • (2004) International Journal of Cancer , vol.112 , Issue.3 , pp. 475-483
    • Andersson, Y.1    Juell, S.2    Fodstad, O.3
  • 4
    • 49649091350 scopus 로고    scopus 로고
    • An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes
    • Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I. An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes. Proc Natl Acad Sci USA 2008;105:11311-13116.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11311-13116
    • Onda, M.1    Beers, R.2    Xiang, L.3    Nagata, S.4    Wang, Q.C.5    Pastan, I.6
  • 6
    • 77954566627 scopus 로고    scopus 로고
    • ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol
    • Traini R, Ben-Josef G, Pastrana DV, et al. ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol. Mol Cancer Ther 2010;9:2007- 2015.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2007-2015
    • Traini, R.1    Ben-Josef, G.2    Pastrana, D.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.