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Volumn 57, Issue 6, 2011, Pages 921-929

Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy

Author keywords

Adoptive immunotherapy; Embryonal rhabdomyosarcoma; Immunotherapy; Regulatory T cells; Rhabdomyosarcoma; Tumor antigen; Tumor vaccine

Indexed keywords

CANCER VACCINE; CD4 ANTIGEN; EMBRYONAL RHABDOMYOSARCOMA VACCINE; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PC61; MUTANT PROTEIN; PROTEIN P53; SCATTER FACTOR; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 80052686056     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.23048     Document Type: Article
Times cited : (28)

References (46)
  • 1
    • 0035155499 scopus 로고    scopus 로고
    • Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: An intergroup rhabdomyosarcoma study
    • Pappo AS, Lyden E, Breneman J, et al. Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: An intergroup rhabdomyosarcoma study. J Clin Oncol 2001;19:213-219.
    • (2001) J Clin Oncol , vol.19 , pp. 213-219
    • Pappo, A.S.1    Lyden, E.2    Breneman, J.3
  • 2
    • 0036171172 scopus 로고    scopus 로고
    • Irinotecan for pediatric solid tumors: The Memorial Sloan-Kettering experience
    • Cosetti M, Wexler LH, Calleja E, et al. Irinotecan for pediatric solid tumors: The Memorial Sloan-Kettering experience. J Pediatr Hematol Oncol 2002;24:101-105.
    • (2002) J Pediatr Hematol Oncol , vol.24 , pp. 101-105
    • Cosetti, M.1    Wexler, L.H.2    Calleja, E.3
  • 3
    • 4644335909 scopus 로고    scopus 로고
    • Cyclophosphamide dose intensification during induction therapy for intermediate-risk pediatric rhabdomyosarcoma is feasible but does not improve outcome: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group
    • Spunt SL, Smith LM, Ruymann FB, et al. Cyclophosphamide dose intensification during induction therapy for intermediate-risk pediatric rhabdomyosarcoma is feasible but does not improve outcome: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. Clin Cancer Res 2004;10:6072-6079.
    • (2004) Clin Cancer Res , vol.10 , pp. 6072-6079
    • Spunt, S.L.1    Smith, L.M.2    Ruymann, F.B.3
  • 4
    • 18744413524 scopus 로고    scopus 로고
    • Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma-A report from the Intergroup Rhabdomyosarcoma Study IV
    • Breneman JC, Lyden E, Pappo AS, et al. Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma-A report from the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol 2003;21:78-84.
    • (2003) J Clin Oncol , vol.21 , pp. 78-84
    • Breneman, J.C.1    Lyden, E.2    Pappo, A.S.3
  • 5
    • 0032722352 scopus 로고    scopus 로고
    • Survival after relapse in children and adolescents with rhabdomyosarcoma: A report from the Intergroup Rhabdomyosarcoma Study Group
    • Pappo AS, Anderson JR, Crist WM, et al. Survival after relapse in children and adolescents with rhabdomyosarcoma: A report from the Intergroup Rhabdomyosarcoma Study Group. J Clin Oncol 1999;17:3487-3493.
    • (1999) J Clin Oncol , vol.17 , pp. 3487-3493
    • Pappo, A.S.1    Anderson, J.R.2    Crist, W.M.3
  • 6
    • 33749599695 scopus 로고    scopus 로고
    • Chronic health conditions in adult survivors of childhood cancer
    • Oeffinger KC, Mertens AC, Sklar CA, et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med 2006;355:1572-1582.
    • (2006) N Engl J Med , vol.355 , pp. 1572-1582
    • Oeffinger, K.C.1    Mertens, A.C.2    Sklar, C.A.3
  • 7
    • 0028031582 scopus 로고
    • Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2
    • Rosenberg SA, Yannelli JR, Yang JC, et al. Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. J Natl Cancer Inst 1994;86:1159-1166.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1159-1166
    • Rosenberg, S.A.1    Yannelli, J.R.2    Yang, J.C.3
  • 8
    • 0029882491 scopus 로고    scopus 로고
    • Growth of tumor-infiltrating lymphocytes from human solid cancers: Summary of a 5-year experience
    • Yannelli JR, Hyatt C, McConnell S, et al. Growth of tumor-infiltrating lymphocytes from human solid cancers: Summary of a 5-year experience. Int J Cancer 1996;65:413-421.
    • (1996) Int J Cancer , vol.65 , pp. 413-421
    • Yannelli, J.R.1    Hyatt, C.2    McConnell, S.3
  • 9
    • 0025847546 scopus 로고
    • Continuous interleukin-2 and lymphokine-activated killer cells for advanced cancer: A National Biotherapy Study Group trial
    • Dillman RO, Oldham RK, Tauer KW, et al. Continuous interleukin-2 and lymphokine-activated killer cells for advanced cancer: A National Biotherapy Study Group trial. J Clin Oncol 1991;9:1233-1240.
    • (1991) J Clin Oncol , vol.9 , pp. 1233-1240
    • Dillman, R.O.1    Oldham, R.K.2    Tauer, K.W.3
  • 10
    • 33744792341 scopus 로고    scopus 로고
    • Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
    • Beck KE, Blansfield JA, Tran KQ, et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol 2006;24:2283-2289.
    • (2006) J Clin Oncol , vol.24 , pp. 2283-2289
    • Beck, K.E.1    Blansfield, J.A.2    Tran, K.Q.3
  • 11
    • 0031931827 scopus 로고    scopus 로고
    • Infusion of donor peripheral blood mononuclear cells to treat relapse after transplantation for chronic myelogenous leukemia
    • Porter DL, Antin JH. Infusion of donor peripheral blood mononuclear cells to treat relapse after transplantation for chronic myelogenous leukemia. Hematol Oncol Clin North Am 1998;12:123-150.
    • (1998) Hematol Oncol Clin North Am , vol.12 , pp. 123-150
    • Porter, D.L.1    Antin, J.H.2
  • 12
    • 34748918373 scopus 로고    scopus 로고
    • Lessons from randomized phase III studies with active cancer immunotherapies-Outcomes from the 2006 meeting of the Cancer Vaccine Consortium (CVC)
    • Finke LH, Wentworth K, Blumenstein B, et al. Lessons from randomized phase III studies with active cancer immunotherapies-Outcomes from the 2006 meeting of the Cancer Vaccine Consortium (CVC). Vaccine 2007;25:B97-B109.
    • (2007) Vaccine , vol.25
    • Finke, L.H.1    Wentworth, K.2    Blumenstein, B.3
  • 13
    • 33646679596 scopus 로고    scopus 로고
    • Donor leukocyte infusions after unrelated donor hematopoietic stem cell transplantation
    • Loren AW, Porter DL. Donor leukocyte infusions after unrelated donor hematopoietic stem cell transplantation. Curr Opin Oncol 2006;18:107-114.
    • (2006) Curr Opin Oncol , vol.18 , pp. 107-114
    • Loren, A.W.1    Porter, D.L.2
  • 14
    • 39149136228 scopus 로고    scopus 로고
    • Osteosarcoma: The addition of muramyl tripeptide to chemotherapy improves overall survival-A report from the Children's Oncology Group
    • Meyers PA, Schwartz CL, Krailo MD, et al. Osteosarcoma: The addition of muramyl tripeptide to chemotherapy improves overall survival-A report from the Children's Oncology Group. J Clin Oncol 2008;26:633-638.
    • (2008) J Clin Oncol , vol.26 , pp. 633-638
    • Meyers, P.A.1    Schwartz, C.L.2    Krailo, M.D.3
  • 15
    • 55549145071 scopus 로고    scopus 로고
    • Virus-specific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
    • Pule MA, Savoldo B, Myers GD, et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma. Nat Med 2008;14:1264-1270.
    • (2008) Nat Med , vol.14 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3
  • 16
    • 0042024964 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma
    • Weigel BJ, Rodeberg DA, Krieg AM, et al. CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma. Clin Cancer Res 2003;9:3105-3114.
    • (2003) Clin Cancer Res , vol.9 , pp. 3105-3114
    • Weigel, B.J.1    Rodeberg, D.A.2    Krieg, A.M.3
  • 17
    • 0036851869 scopus 로고    scopus 로고
    • Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
    • Sharp R, Recio JA, Jhappan C, et al. Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis. Nat Med 2002;8:1276-1280.
    • (2002) Nat Med , vol.8 , pp. 1276-1280
    • Sharp, R.1    Recio, J.A.2    Jhappan, C.3
  • 18
    • 34347219009 scopus 로고    scopus 로고
    • Metagene projection for cross-platform, cross-species characterization of global transcriptional states
    • Tamayo P, Scanfeld D, Ebert BL, et al. Metagene projection for cross-platform, cross-species characterization of global transcriptional states. Proc Natl Acad Sci USA 2007;104:5959-5964.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5959-5964
    • Tamayo, P.1    Scanfeld, D.2    Ebert, B.L.3
  • 20
    • 51649092873 scopus 로고    scopus 로고
    • Molecular characterization of the pediatric preclinical testing panel
    • Neale G, Su X, Morton CL, et al. Molecular characterization of the pediatric preclinical testing panel. Clin Cancer Res 2008;14:4572-4583.
    • (2008) Clin Cancer Res , vol.14 , pp. 4572-4583
    • Neale, G.1    Su, X.2    Morton, C.L.3
  • 21
    • 33947511816 scopus 로고    scopus 로고
    • Diagnosis of the small round blue cell tumors using multiplex polymerase chain reaction
    • Chen QR, Vansant G, Oades K, et al. Diagnosis of the small round blue cell tumors using multiplex polymerase chain reaction. J Mol Diagn 2007;9:80-88.
    • (2007) J Mol Diagn , vol.9 , pp. 80-88
    • Chen, Q.R.1    Vansant, G.2    Oades, K.3
  • 22
    • 33751183096 scopus 로고    scopus 로고
    • Defining the gene expression signature of rhabdomyosarcoma by meta-analysis
    • Romualdi C, De Pitta C, Tombolan L, et al. Defining the gene expression signature of rhabdomyosarcoma by meta-analysis. BMC Genomics 2006;7:287.
    • (2006) BMC Genomics , vol.7 , pp. 287
    • Romualdi, C.1    De Pitta, C.2    Tombolan, L.3
  • 23
    • 34247588130 scopus 로고    scopus 로고
    • CD25+ regulatory T cell inhibition enhances vaccine-induced immunity to neuroblastoma
    • Johnson BD, Jing W, Orentas RJ. CD25+ regulatory T cell inhibition enhances vaccine-induced immunity to neuroblastoma. J Immunother 2007;30:203-214.
    • (2007) J Immunother , vol.30 , pp. 203-214
    • Johnson, B.D.1    Jing, W.2    Orentas, R.J.3
  • 24
    • 67349252263 scopus 로고    scopus 로고
    • Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches
    • Fry TJ, Shand JL, Milliron M, et al. Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches. Cancer Immunol Immunother 2009;58:1257-1264.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1257-1264
    • Fry, T.J.1    Shand, J.L.2    Milliron, M.3
  • 25
    • 43149117675 scopus 로고    scopus 로고
    • Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma
    • Thistlethwaite FC, Elkord E, Griffiths RW, et al. Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma. Cancer Immunol Immunother 2008;57:623-634.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 623-634
    • Thistlethwaite, F.C.1    Elkord, E.2    Griffiths, R.W.3
  • 26
    • 46949105036 scopus 로고    scopus 로고
    • Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets
    • Sportes C, Hakim FT, Memon SA, et al. Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets. J Exp Med 2008;205:1701-1714.
    • (2008) J Exp Med , vol.205 , pp. 1701-1714
    • Sportes, C.1    Hakim, F.T.2    Memon, S.A.3
  • 27
    • 72549102587 scopus 로고    scopus 로고
    • Partial CD4 depletion reduces regulatory T cells induced by multiple vaccinations and restores therapeutic efficacy
    • Lacelle MG, Jensen SM, Fox BA. Partial CD4 depletion reduces regulatory T cells induced by multiple vaccinations and restores therapeutic efficacy. Clin Cancer Res 2009;15:6881-6890.
    • (2009) Clin Cancer Res , vol.15 , pp. 6881-6890
    • Lacelle, M.G.1    Jensen, S.M.2    Fox, B.A.3
  • 28
    • 70449726875 scopus 로고    scopus 로고
    • Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts
    • Cui Y, Zhang H, Meadors J, et al. Harnessing the physiology of lymphopenia to support adoptive immunotherapy in lymphoreplete hosts. Blood 2009;114:3831-3840.
    • (2009) Blood , vol.114 , pp. 3831-3840
    • Cui, Y.1    Zhang, H.2    Meadors, J.3
  • 29
    • 0037372307 scopus 로고    scopus 로고
    • Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma
    • Rousseau RF, Haight AE, Hirschmann-Jax C, et al. Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma. Blood 2003;101:1718-1726.
    • (2003) Blood , vol.101 , pp. 1718-1726
    • Rousseau, R.F.1    Haight, A.E.2    Hirschmann-Jax, C.3
  • 30
    • 0035576891 scopus 로고    scopus 로고
    • Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression
    • Geiger JD, Hutchinson RJ, Hohenkirk LF, et al. Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression. Cancer Res 2001;61:8513-8519.
    • (2001) Cancer Res , vol.61 , pp. 8513-8519
    • Geiger, J.D.1    Hutchinson, R.J.2    Hohenkirk, L.F.3
  • 31
    • 33846445664 scopus 로고    scopus 로고
    • Early lymphocyte recovery as a prognostic indicator for high-risk Ewing sarcoma
    • De Angulo G, Hernandez M, Morales-Arias J, et al. Early lymphocyte recovery as a prognostic indicator for high-risk Ewing sarcoma. J Pediatr Hematol Oncol 2007;29:48-52.
    • (2007) J Pediatr Hematol Oncol , vol.29 , pp. 48-52
    • De Angulo, G.1    Hernandez, M.2    Morales-Arias, J.3
  • 33
    • 33747387248 scopus 로고    scopus 로고
    • Absolute lymphocyte count predicts overall survival in follicular lymphomas
    • Siddiqui M, Ristow K, Markovic SN, et al. Absolute lymphocyte count predicts overall survival in follicular lymphomas. Br J Haematol 2006;134:596-601.
    • (2006) Br J Haematol , vol.134 , pp. 596-601
    • Siddiqui, M.1    Ristow, K.2    Markovic, S.N.3
  • 34
    • 3442877804 scopus 로고    scopus 로고
    • Bedside to bench and back again: How animal models are guiding the development of new immunotherapies for cancer
    • Finkelstein SE, Heimann DM, Klebanoff CA, et al. Bedside to bench and back again: How animal models are guiding the development of new immunotherapies for cancer. J Leukoc Biol 2004;76:333-337.
    • (2004) J Leukoc Biol , vol.76 , pp. 333-337
    • Finkelstein, S.E.1    Heimann, D.M.2    Klebanoff, C.A.3
  • 35
    • 0031852722 scopus 로고    scopus 로고
    • gp100/pmel 17 is a murine tumor rejection antigen: Induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand
    • Overwijk WW, Tsung A, Irvine KR, et al. gp100/pmel 17 is a murine tumor rejection antigen: Induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand. J Exp Med 1998;188:277-286.
    • (1998) J Exp Med , vol.188 , pp. 277-286
    • Overwijk, W.W.1    Tsung, A.2    Irvine, K.R.3
  • 36
    • 31644451518 scopus 로고    scopus 로고
    • Suppression of anti-cancer immunity by regulatory T cells: Back to the future
    • Orentas RJ, Kohler ME, Johnson BD. Suppression of anti-cancer immunity by regulatory T cells: Back to the future. Semin Cancer Biol 2006;16:137-149.
    • (2006) Semin Cancer Biol , vol.16 , pp. 137-149
    • Orentas, R.J.1    Kohler, M.E.2    Johnson, B.D.3
  • 37
    • 34247595587 scopus 로고    scopus 로고
    • Immune reconstitution prevents metastatic recurrence of murine osteosarcoma
    • Merchant MS, Melchionda F, Sinha M, et al. Immune reconstitution prevents metastatic recurrence of murine osteosarcoma. Cancer Immunol Immunother 2007;56:1037-1046.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1037-1046
    • Merchant, M.S.1    Melchionda, F.2    Sinha, M.3
  • 38
    • 1442304609 scopus 로고    scopus 로고
    • Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
    • Yu Y, Khan J, Khanna C, et al. Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Med 2004;10:175-181.
    • (2004) Nat Med , vol.10 , pp. 175-181
    • Yu, Y.1    Khan, J.2    Khanna, C.3
  • 39
    • 66149138870 scopus 로고    scopus 로고
    • Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma
    • Nishijo K, Chen QR, Zhang L, et al. Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma. Cancer Res 2009;69:2902-2911.
    • (2009) Cancer Res , vol.69 , pp. 2902-2911
    • Nishijo, K.1    Chen, Q.R.2    Zhang, L.3
  • 40
    • 66949167418 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics
    • Grass B, Wachtel M, Behnke S, et al. Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics. Histopathology 2009;54:873-879.
    • (2009) Histopathology , vol.54 , pp. 873-879
    • Grass, B.1    Wachtel, M.2    Behnke, S.3
  • 41
    • 0038207050 scopus 로고    scopus 로고
    • Dual expression of CD80 and CD86 produces a tumor vaccine superior to single expression of either molecule
    • Johnson BD, Yan X, Schauer DW, et al. Dual expression of CD80 and CD86 produces a tumor vaccine superior to single expression of either molecule. Cell Immunol 2003;222:15-26.
    • (2003) Cell Immunol , vol.222 , pp. 15-26
    • Johnson, B.D.1    Yan, X.2    Schauer, D.W.3
  • 42
    • 0028074499 scopus 로고
    • Lymphocyte depletion during treatment with intensive chemotherapy for cancer
    • Mackall CL, Fleisher TA, Brown MR, et al. Lymphocyte depletion during treatment with intensive chemotherapy for cancer. Blood 1994;84:2221-2228.
    • (1994) Blood , vol.84 , pp. 2221-2228
    • Mackall, C.L.1    Fleisher, T.A.2    Brown, M.R.3
  • 43
    • 34248193253 scopus 로고    scopus 로고
    • Immune surveillance of tumors
    • Swann JB, Smyth MJ. Immune surveillance of tumors. J Clin Invest 2007;117:1137-1146.
    • (2007) J Clin Invest , vol.117 , pp. 1137-1146
    • Swann, J.B.1    Smyth, M.J.2
  • 44
    • 10844269645 scopus 로고    scopus 로고
    • Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells
    • Prasad SJ, Farrand KJ, Matthews SA, et al. Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells. J Immunol 2005;174:90-98.
    • (2005) J Immunol , vol.174 , pp. 90-98
    • Prasad, S.J.1    Farrand, K.J.2    Matthews, S.A.3
  • 45
    • 59449097574 scopus 로고    scopus 로고
    • Immune stimulatory antigen loaded particles combined with depletion of regulatory T-cells induce potent tumor specific immunity in a mouse model of melanoma
    • Goforth R, Salem AK, Zhu X, et al. Immune stimulatory antigen loaded particles combined with depletion of regulatory T-cells induce potent tumor specific immunity in a mouse model of melanoma. Cancer Immunol Immunother 2009;58:517-530.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 517-530
    • Goforth, R.1    Salem, A.K.2    Zhu, X.3
  • 46
    • 68549132533 scopus 로고    scopus 로고
    • Dramatic efficacy improvement of a DC-based vaccine against AML by CD25 T cell depletion allowing the induction of a long-lasting T cell response
    • Delluc S, Hachem P, Rusakiewicz S, et al. Dramatic efficacy improvement of a DC-based vaccine against AML by CD25 T cell depletion allowing the induction of a long-lasting T cell response. Cancer Immunol Immunother 2009;58:1669-1677.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1669-1677
    • Delluc, S.1    Hachem, P.2    Rusakiewicz, S.3


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