Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells

British Journal of Cancer

Volumn 101, Issue 12, 2009, Pages 2030-2037

  Hirotsu, M ^a   Setoguchi, T ^a   Matsunoshita, Y ^a   Sasaki, H ^a   Nagao, H ^a   Gao, H ^a   Sugimura, K ^b   Komiya, S ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Cancer stem cell; Fibroblast growth factor receptor 3 (FGFR3); Rhabdomyosarcoma; Sarcoma initiating cells

Indexed keywords

CD34 ANTIGEN; DESMIN; DYSTROPHIN; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MYOGENIC FACTOR 5; MYOGENIN; MYOSIN HEAVY CHAIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX7; TRANSCRIPTION FACTOR SOX2;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYONAL RHABDOMYOSARCOMA; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; RHABDOMYOSARCOMA; TUMOR BIOPSY; XENOGRAFT;

ANIMALS; BIOPSY; CELL DIFFERENTIATION; CELL LINE, TUMOR; FLOW CYTOMETRY; HUMANS; MICE; NEOPLASTIC STEM CELLS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; RHABDOMYOSARCOMA;

EID: 71649083910     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605407     Document Type: Article

References (51)

1. Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF (2004) Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14: 43-47
2. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988 (Pubitemid 36418143)
3. Bobis S, Jarocha D, Majka M (2006) Mesenchymal stem cells: characteristics and clinical applications. Folia Histochem Cytobiol 44: 215-230
4. Bonnet D, Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3:730-737
5. Caligaris-Cappio F, Bergui L, Tesio L, Pizzolo G, Malavasi F, Chilosi M, Campana D, van Camp B, Janossy G (1985) Identification of malignant plasma cell precursors in the bone marrow of multiple myeloma. J Clin Invest 76: 1243-1251
6. Cappellen D, De Oliveira C, Ricol D, de Medina S, Bourdin J, Sastre-Garau X, Chopin D, Thiery JP, Radvanyi F (1999) Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat Genet 23: 18-20
7. Chearwae W, Bright JJ (2008) PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. Br J Cancer 99:2044-2053
8. Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, Visvader J, Weissman IL, Wahl GM (2006) Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 66: 9339-9344
9. Clarke MF, Fuller M (2006) Stem cells and cancer: two faces of eve. Cell 124:1111-1115
10. Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65:10946-10951
11. Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF (2007) Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 104: 10158-10163
12. Erices A, Conget P, Minguell JJ (2000) Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol 109: 235-242
13. Eswarakumar VP, Lax I, Schlessinger J (2005) Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev 16:139-149
14. Fang D, Nguyen TK, Leishear K, Finko R, Kulp AN, Hotz S, Van Belle PA, Xu X, Elder DE, Herlyn M (2005) A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 65: 9328-9337
15. Gallego Melcon S, Sanchez de Toledo Codina J (2007) Molecular biology of rhabdomyosarcoma. Clin Transl Oncol 9: 415-419
16. Giard DJ, Aaronson SA, Todaro GJ, Arnstein P, Kersey JH, Dosik H, Parks WP (1973) In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst 51: 1417-1423
17. Guthridge M, Wilson M, Cowling J, Bertolini J, Hearn MT (1992) The role of basic fibroblast growth factor in skeletal muscle regeneration. Growth Factors 6: 53-63
18. Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C (2007) Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323
19. Jones EA, English A, Kinsey SE, Straszynski L, Emery P, Ponchel F, McGonagle D (2006) Optimization of a flow cytometry-based protocol for detection and phenotypic characterization of multipotent mesench-ymal stromal cells from human bone marrow. Cytometry B Clin Cytom 70: 391-399
20. Kastrinakis NG, Gorgoulis VG, Foukas PG, Dimopoulos MA, Kittas C (2000) Molecular aspects of multiple myeloma. Ann Oncol 11: 1217-1228
21. Kim CFB, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, Crowley D, Bronson RT, Jacks T (2005) Identification of bronchioalveo-lar stem cells in normal lung and lung cancer. Cell 121: 823-835
22. Kitchens DL, Snyder EY, Gottlieb DI (1994) FGF and EGF are mitogens for immortalized neural progenitors. J Neurobiol 25: 797-807
23. Kondo T, Setoguchi T, Taga T (2004) Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA 101: 781-786
24. Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367: 645-648
25. Lefaucheur JP, Sebille A (1995) Basic fibroblast growth factor promotes in vivo muscle regeneration in murine muscular dystrophy. Neurosci Lett 202: 121-124
26. Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM (2007) Identification of pancreatic cancer stem cells. Cancer Res 67: 1030-1037 (Pubitemid 46270758)
27. Loebinger MR, Giangreco A, Groot KR, Prichard L, Allen K, Simpson C, Bazley L, Navani N, Tibrewal S, Davies D, Janes SM (2008) Squamous cell cancers contain a side population of stem-like cells that are made chemosensitive by ABC transporter blockade. Br J Cancer 98: 380-387
28. Maric D, Fiorio Pla A, Chang YH, Barker JL (2007) Self-renewing and differentiating properties of cortical neural stem cells are selectively regulated by basic fibroblast growth factor (FGF) signaling via specific FGF receptors. J Neurosci 27: 1836-1852
29. Marmur R, Kessler JA, Zhu G, Gokhan S, Mehler MF (1998) Differentiation of oligodendroglial progenitors derived from cortical multipotent cells requires extrinsic signals including activation of gp130/LIFbeta receptors. J Neurosci 18: 9800-9811
30. McAllister RM, Melnyk J, Finkelstein JZ, Adams Jr EC, Gardner MB (1969) Cultivation in vitro of cells derived from a human rhabdomyosarcoma. Cancer 24: 520-526
31. Mizrak D, Brittan M, Alison MR (2008) CD133: molecule of the moment. J Pathol 214: 3-9
32. Onose H, Emoto N, Sugihara H, Shimizu K, Wakabayashi I (1999) Overexpression of fibroblast growth factor receptor 3 in a human thyroid carcinoma cell line results in overgrowth of the confluent cultures. Eur J Endocrinol 140: 169-173
33. Ornitz DM, Leder P (1992) Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3. J Biol Chem 267: 16305-16311
34. Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, Weissman IL, Clarke MF, Ailles LE (2007) Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 104: 973-978
35. Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ (2008) Efficient tumour formation by single human melanoma cells. Nature 456: 593-598
36. Raguz S, Yague E (2008) Resistance to chemotherapy: new treatments and novel insights into an old problem. Br J Cancer 99: 387-391
37. Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115
38. Robinson D, Hasharoni A, Cohen N, Yayon A, Moskowitz RM, Nevo Z (1999) Fibroblast growth factor receptor-3 as a marker for precartila-ginous stem cells. Clin Orthop Relat Res 367: S163-S175
39. Sekiguchi M, Shiroko Y, Suzuki T, Imada M, Miyahara M, Fujii G (1985) Characterization of a human rhabdomyosarcoma cell strain in tissue culture. Biomed Pharmacother 39: 372-380
40. Setoguchi T, Taga T, Kondo T (2004) Cancer stem cells persist in many cancer cell lines. Cell Cycle 3: 414-415
41. Sheehan SM, Allen RE (1999) Skeletal muscle satellite cell proliferation in response to members of the fibroblast growth factor family and hepatocyte growth factor. J Cell Physiol 181: 499-506
42. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828
43. Small D (2008) Targeting FLT3 for the treatment of leukemia. Semin Hematol 45: S17-S21
44. Sogos V, Balaci L, Ennas MG, Delloera P, Presta M, Gremo F (1998) Developmentally regulated expression and localization of fibroblast growth factor receptors in the human muscle. Dev Dyn 211: 362-373
45. Tanaka M, Setoguchi T, Hirotsu M, Gao H, Sasaki H, Matsunoshita Y, Komiya S (2009) Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. Br J Cancer 100: 1957-1965
46. Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SG (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92: 205-216
47. Trumpp A, Wiestler OD (2008) Mechanisms of disease: cancer stem cells-targeting the evil twin. Nat Clin Pract Oncol 5: 337-347
48. Vallier L, Pedersen RA (2005) Human embryonic stem cells: an in vitro model to study mechanisms controlling pluripotency in early mammalian development. Stem Cell Rev 1: 119-130
49. Wolff EM, Liang G, Jones PA (2005) Mechanisms of disease: genetic and epigenetic alterations that drive bladder cancer. Nat Clin Pract Urol 2: 502-510
50. Xu Q, Yuan X, Tunici P, Liu G, Fan X, Xu M, Hu J, Hwang JY, Farkas DL, Black KL, Yu JS (2009) Isolation of tumour stem-like cells from benign tumours. Br J Cancer 101: 303-311
51. Yagasaki F, Wakao D, Yokoyama Y, Uchida Y, Murohashi I, Kayano H, Taniwaki M, Matsuda A, Bessho M (2001) Fusion of ETV6 to fibroblast growth factor receptor 3 in peripheral T-cell lymphoma with a t(4;12)(p16;p13) chromosomal translocation. Cancer Res 61: 8371-8374