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Volumn 9, Issue 7, 2007, Pages 415-419

Molecular biology of rhabdomyosarcoma

Author keywords

Genetic abnormalities; Minimal disseminated disease; Rhabdomyosarcoma

Indexed keywords

CHOLINERGIC RECEPTOR; MESSENGER RNA; MYOD1 PROTEIN; MYOGENIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX7; FORKHEAD TRANSCRIPTION FACTOR; FOXO1A PROTEIN, HUMAN; PAIRED BOX TRANSCRIPTION FACTOR; PAX3 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 35748940315     PISSN: 1699048X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12094-007-0079-3     Document Type: Article
Times cited : (46)

References (38)
  • 1
    • 0004111039 scopus 로고    scopus 로고
    • IARC 1998 (IICC-2) IARC Scientific Publication No. 144
    • IARC (1998) International incidence of childhood cancer, 1998 (IICC-2), Vol. II. IARC Scientific Publication No. 144
    • (1998) International Incidence of Childhood Cancer , vol.2
  • 2
    • 1842791530 scopus 로고    scopus 로고
    • Soft tissue sarcomas of childhood
    • Meyer WH, Spunt SL (2004) Soft tissue sarcomas of childhood. Cancer Treat Rev 30:269-280
    • (2004) Cancer Treat Rev , vol.30 , pp. 269-280
    • Meyer, W.H.1    Spunt, S.L.2
  • 4
    • 0035876634 scopus 로고    scopus 로고
    • Intergroup rhabdomyosarcoma study-IV: Results for patients with nonmetastatic disease
    • Crist WM, Anderson JR, Meza JL et al (2001) Intergroup rhabdomyosarcoma study-IV: Results for patients with nonmetastatic disease. J Clin Oncol 19:3091-3102
    • (2001) J Clin Oncol , vol.19 , pp. 3091-3102
    • Crist, W.M.1    Anderson, J.R.2    Meza, J.L.3
  • 5
    • 0035008973 scopus 로고    scopus 로고
    • Rhabdomyosarcoma and Undifferentiated Sarcoma in the First Two Decades of Life: A Selective Review of Intergroup Rhabdomyosarcoma Study Group Experience and Rationale for Intergroup Rhabdomyosarcoma Study V
    • Raney RB, Anderson JR, Barr FG et al (2001) Rhabdomyosarcoma and Undifferentiated Sarcoma in the First Two Decades of Life: A Selective Review of Intergroup Rhabdomyosarcoma Study Group Experience and Rationale for Intergroup Rhabdomyosarcoma Study V. Am J Pediatr Hematol Oncol 23:215-220
    • (2001) Am J Pediatr Hematol Oncol , vol.23 , pp. 215-220
    • Raney, R.B.1    Anderson, J.R.2    Barr, F.G.3
  • 6
    • 0028978780 scopus 로고
    • Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification - An Intergroup Rhabdomyosarcoma Study
    • Newton WA Jr, Gehan EA, Webber BL et al (1995) Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification - an Intergroup Rhabdomyosarcoma Study. Cancer 76:1073-1085
    • (1995) Cancer , vol.76 , pp. 1073-1085
    • Newton Jr., W.A.1    Gehan, E.A.2    Webber, B.L.3
  • 7
  • 8
    • 0026501788 scopus 로고    scopus 로고
    • Human chromosome 11 contains two different growth suppresser genes for embryonal rhabdomyosarcoma
    • Loh EWJ, Scrable HJ, Livanos E et al. Human chromosome 11 contains two different growth suppresser genes for embryonal rhabdomyosarcoma. Proc Natl Acad Sci U S A 89:1755-1759
    • Proc Natl Acad Sci U S A , vol.89 , pp. 1755-1759
    • Loh, E.W.J.1    Scrable, H.J.2    Livanos, E.3
  • 9
    • 0034088133 scopus 로고    scopus 로고
    • Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization: An Intergroup Rhabdomyosarcoma Study
    • Bridge JA, Liu J, Weibolt V et al (2000) Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization: An Intergroup Rhabdomyosarcoma Study. Genes Chromosome Cancer 27: 337-344
    • (2000) Genes Chromosome Cancer , vol.27 , pp. 337-344
    • Bridge, J.A.1    Liu, J.2    Weibolt, V.3
  • 10
    • 0031406578 scopus 로고    scopus 로고
    • Molecular genetics and pathogenesis of rhabdomyosarcoma
    • Barr FG (1997) Molecular genetics and pathogenesis of rhabdomyosarcoma. J Pediatr Hematol Oncol 19:483-491
    • (1997) J Pediatr Hematol Oncol , vol.19 , pp. 483-491
    • Barr, F.G.1
  • 11
    • 0035839886 scopus 로고    scopus 로고
    • Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
    • Barr FG (2001) Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma. Oncogene 20:5736-5746
    • (2001) Oncogene , vol.20 , pp. 5736-5746
    • Barr, F.G.1
  • 12
    • 0027521658 scopus 로고
    • Fusion of a fork head domain gene to PAX 3 in the solid tumour alveolar rhabdomyosarcoma
    • Galili N, Davis RJ, Fredericks WJ et al (1993) Fusion of a fork head domain gene to PAX 3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet 5:230-235
    • (1993) Nat Genet , vol.5 , pp. 230-235
    • Galili, N.1    Davis, R.J.2    Fredericks, W.J.3
  • 13
    • 0028364374 scopus 로고
    • Fusion of PAX7 to the FKHR by the variant t(1;13) (p36;q14)translocation in alveolar rhabdomyosarcomas
    • Davis RJ, D'Cruz CM, Lowell MA et al (1994) Fusion of PAX7 to the FKHR by the variant t(1;13) (p36;q14)translocation in alveolar rhabdomyosarcomas. Cancer Res 54:2869-2872
    • (1994) Cancer Res , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lowell, M.A.3
  • 14
    • 0029154584 scopus 로고
    • Wild-type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains
    • Bennicelli JL, Fredericks WJ, Wilson RB et al (1995) Wild-type PAX3 protein and the PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma contain potent, structurally distinct transcriptional activation domains. Oncogene 11: 119-130
    • (1995) Oncogene , vol.11 , pp. 119-130
    • Bennicelli, J.L.1    Fredericks, W.J.2    Wilson, R.B.3
  • 15
    • 0029559722 scopus 로고
    • Transcription factor families: Muscling in on the myogenic program
    • Ludolph DC, Konieczny SF (1995) Transcription factor families: Muscling in on the myogenic program. FASEB J 9:1595-1604
    • (1995) FASEB J , vol.9 , pp. 1595-1604
    • Ludolph, D.C.1    Konieczny, S.F.2
  • 16
    • 0029796402 scopus 로고    scopus 로고
    • The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture
    • Scheidler S, Fredericks WJ, Rauscher FJ III (1996) The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture. Proc Natl Acad Sci U S A 93:9805-9809
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9805-9809
    • Scheidler, S.1    Fredericks, W.J.2    Rauscher III, F.J.3
  • 17
    • 0029826488 scopus 로고    scopus 로고
    • Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins
    • Bernasconi M, Remppis A, Fredericks WJ et al (1996) Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins. Proc Natl Acad Sci U S A 93: 13164-13169
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13164-13169
    • Bernasconi, M.1    Remppis, A.2    Fredericks, W.J.3
  • 19
    • 0036605806 scopus 로고    scopus 로고
    • PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the Children's Oncology Group
    • Sorensen PHB, Lynch JC, Qualman SJ et al (2002) PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the Children's Oncology Group. J Clin Oncol 20:2672-2679
    • (2002) J Clin Oncol , vol.20 , pp. 2672-2679
    • Sorensen, P.H.B.1    Lynch, J.C.2    Qualman, S.J.3
  • 20
    • 0028353848 scopus 로고
    • MYCN gene amplification in rhabdomyosarcoma
    • Driman D, Thorner PS, Greenberg ML et al (1994) MYCN gene amplification in rhabdomyosarcoma. Cancer 15:2231-2237
    • (1994) Cancer , vol.15 , pp. 2231-2237
    • Driman, D.1    Thorner, P.S.2    Greenberg, M.L.3
  • 21
    • 0027728787 scopus 로고
    • Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: Some amplicons do not include MDM2
    • Forus A, Florenes VA, Maelandsmo GM et al (1993) Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: Some amplicons do not include MDM2. Cell Growth Differ 4:1065-1070
    • (1993) Cell Growth Differ , vol.4 , pp. 1065-1070
    • Forus, A.1    Florenes, V.A.2    Maelandsmo, G.M.3
  • 22
    • 0030962761 scopus 로고    scopus 로고
    • Allelotype of pediatric rhabdomyosarcoma
    • Visser M, Sijmons C, Bras J et al (1997) Allelotype of pediatric rhabdomyosarcoma. Oncogene 15:1309-1314
    • (1997) Oncogene , vol.15 , pp. 1309-1314
    • Visser, M.1    Sijmons, C.2    Bras, J.3
  • 23
    • 4344713343 scopus 로고    scopus 로고
    • Characterization of sarcomas by means of gene expression
    • Skubitz KM, Skubitz AP (2004) Characterization of sarcomas by means of gene expression. J Lab Clin Med 144:78-91
    • (2004) J Lab Clin Med , vol.144 , pp. 78-91
    • Skubitz, K.M.1    Skubitz, A.P.2
  • 24
    • 27144523169 scopus 로고    scopus 로고
    • Gene expression profiling of human sarcomas: Insights into sarcoma biology
    • Baird K, Davis S, Antonescu CR et al (2005) Gene expression profiling of human sarcomas: Insights into sarcoma biology. Cancer Res 65:9226-9235
    • (2005) Cancer Res , vol.65 , pp. 9226-9235
    • Baird, K.1    Davis, S.2    Antonescu, C.R.3
  • 25
    • 33645054041 scopus 로고    scopus 로고
    • The role of microarray technologies in the study of soft tissue tumours
    • West RB, van de Rijn M (2006) The role of microarray technologies in the study of soft tissue tumours. Histopathology 48:22-31
    • (2006) Histopathology , vol.48 , pp. 22-31
    • West, R.B.1    van de Rijn, M.2
  • 26
    • 0034954414 scopus 로고    scopus 로고
    • Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks
    • Khan J, Wie JS, Ringner M et al (2001) Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks. Nat Med 7:673-679
    • (2001) Nat Med , vol.7 , pp. 673-679
    • Khan, J.1    Wie, J.S.2    Ringner, M.3
  • 27
    • 2942520985 scopus 로고    scopus 로고
    • Profiling and functional annotation of mRNA gene expression in pediatric rhabdomyosarcoma and Ewing's sarcoma
    • Baer C, Nees M, Breit S et al (2004) Profiling and functional annotation of mRNA gene expression in pediatric rhabdomyosarcoma and Ewing's sarcoma. Int J Cancer 110:687-694
    • (2004) Int J Cancer , vol.110 , pp. 687-694
    • Baer, C.1    Nees, M.2    Breit, S.3
  • 28
    • 20044393821 scopus 로고    scopus 로고
    • Full transcriptome analysis of rhabdomyosarcoma, normal, and fetal skeletal muscle: Statistical comparison of multiple SAGE libraries
    • Schaaf GJ, Ruijter JM, van Ruissen F et al (2005) Full transcriptome analysis of rhabdomyosarcoma, normal, and fetal skeletal muscle: statistical comparison of multiple SAGE libraries. FASEB J 19:404-406
    • (2005) FASEB J , vol.19 , pp. 404-406
    • Schaaf, G.J.1    Ruijter, J.M.2    van Ruissen, F.3
  • 29
    • 33751183096 scopus 로고    scopus 로고
    • Defining the gene expression signature of rhabdomyosarcoma by meta-analysis
    • Romualdi C, De Pitta C, Tombolan L et al (2006) Defining the gene expression signature of rhabdomyosarcoma by meta-analysis. BMC Genomics 7:287
    • (2006) BMC Genomics , vol.7 , pp. 287
    • Romualdi, C.1    De Pitta, C.2    Tombolan, L.3
  • 30
    • 0035105525 scopus 로고    scopus 로고
    • Use of reverse transcriptase polymerase chain reaction for diagnosis and staging of alveolar rhabdomyosarcoma, Ewing sarcoma family of tumors, and desmoplastic small round cell tumor
    • Athale U, Shurtleff S, Jenkins J et al (2001) Use of reverse transcriptase polymerase chain reaction for diagnosis and staging of alveolar rhabdomyosarcoma, Ewing sarcoma family of tumors, and desmoplastic small round cell tumor. J Pediatr Hematol Oncol 23:99-104
    • (2001) J Pediatr Hematol Oncol , vol.23 , pp. 99-104
    • Athale, U.1    Shurtleff, S.2    Jenkins, J.3
  • 31
    • 0029810867 scopus 로고    scopus 로고
    • Minimal disease detection in patients with alveolar rhabdomyosarcoma using a reverse transcriptase-polymerase chain reaction method
    • Kelly KM, Womer RB, Barr FG (1996) Minimal disease detection in patients with alveolar rhabdomyosarcoma using a reverse transcriptase-polymerase chain reaction method. Cancer 78:1320-1327
    • (1996) Cancer , vol.78 , pp. 1320-1327
    • Kelly, K.M.1    Womer, R.B.2    Barr, F.G.3
  • 32
    • 0031906855 scopus 로고    scopus 로고
    • Detection of the MyoD1 transcript in rhabdomyosarcoma cell lines and tumor samples by reverse transcription polymerase chain reaction
    • Frascella E, Rosolen A (1998) Detection of the MyoD1 transcript in rhabdomyosarcoma cell lines and tumor samples by reverse transcription polymerase chain reaction. Am J Pathol 152:577-583
    • (1998) Am J Pathol , vol.152 , pp. 577-583
    • Frascella, E.1    Rosolen, A.2
  • 33
    • 0033224439 scopus 로고    scopus 로고
    • A comparison of MyoD1 and fetal acetylcholine receptor expression in childhood tumors and normal tissues: Implications for the molecular diagnosis of minimal disease in rhabdomyosarcomas
    • Gattenloehner S, Dockhorn-Dworniczak B, Leuschner I et al (1999) A comparison of MyoD1 and fetal acetylcholine receptor expression in childhood tumors and normal tissues: Implications for the molecular diagnosis of minimal disease in rhabdomyosarcomas. J Mol Diagn 1:23-31
    • (1999) J Mol Diagn , vol.1 , pp. 23-31
    • Gattenloehner, S.1    Dockhorn-Dworniczak, B.2    Leuschner, I.3
  • 34
    • 33645124782 scopus 로고    scopus 로고
    • Detection of bone marrow micrometastasis and microcirculating disease in rhabdomyosarcoma by a real-time RT-PCR assay
    • Gallego S, Llort A, Roma J (2006) Detection of bone marrow micrometastasis and microcirculating disease in rhabdomyosarcoma by a real-time RT-PCR assay. J Cancer Res Clin Oncol 132:356-362
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 356-362
    • Gallego, S.1    Llort, A.2    Roma, J.3
  • 35
    • 33646041022 scopus 로고    scopus 로고
    • Results of a prospective minimal disseminated disease study in human rhabdomyosarcoma using three different molecular markers
    • Sartori F, Alaggio R, Zanazzo G et al (2006) Results of a prospective minimal disseminated disease study in human rhabdomyosarcoma using three different molecular markers. Cancer 106:1766-1775
    • (2006) Cancer , vol.106 , pp. 1766-1775
    • Sartori, F.1    Alaggio, R.2    Zanazzo, G.3
  • 36
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
    • MacKeigan JP, Murphy LO, Blenis J (2005) Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat Cell Biol 7:591-600
    • (2005) Nat Cell Biol , vol.7 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 37
    • 33846804231 scopus 로고    scopus 로고
    • Imatinib mesylate potentiates topotecan antitumor activity in rhabdomyosarcoma preclinical models
    • McDowell HP, Meco D, Riccardi A et al (2006) Imatinib mesylate potentiates topotecan antitumor activity in rhabdomyosarcoma preclinical models. Int J Cancer 120:1141-1149
    • (2006) Int J Cancer , vol.120 , pp. 1141-1149
    • McDowell, H.P.1    Meco, D.2    Riccardi, A.3
  • 38
    • 34248216623 scopus 로고    scopus 로고
    • Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival
    • Petricoin EF, Espina V, Araujo RP et al (2007) Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res 67:3431-3440
    • (2007) Cancer Res , vol.67 , pp. 3431-3440
    • Petricoin, E.F.1    Espina, V.2    Araujo, R.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.