메뉴 건너뛰기




Volumn 2011, Issue , 2011, Pages

Targeted treatment of differentiated and medullary thyroid cancer

Author keywords

[No Author keywords available]

Indexed keywords

AXITINIB; B RAF KINASE; CABOZANTINIB; CALCITONIN; EXELIXIS; GLUTAMIC ACID; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MOTESANIB; PAZOPANIB; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN RET; SORAFENIB; STEM CELL FACTOR RECEPTOR; SUNITINIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALINE; VANDETANIB; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3; VEMURAFENIB; WITHAFERIN A; XL 281;

EID: 84872221734     PISSN: 20908067     EISSN: 20420072     Source Type: Journal    
DOI: 10.4061/2011/102636     Document Type: Review
Times cited : (6)

References (133)
  • 1
    • 79951996318 scopus 로고    scopus 로고
    • Surveillance, epidemiology, and end results (S. E. E. R. Program)
    • December
    • "Surveillance, Epidemiology, and End Results (S. E. E. R. Program)", Generate custom reports from the cancer statistics review, Seer 9:1975-2007, December 2010, http://seer.cancer.gov/.
    • (2010) Generate Custom Reports from the Cancer Statistics Review, Seer , vol.9 , pp. 1975-2007
  • 2
    • 0032576677 scopus 로고    scopus 로고
    • Papillary and follicular thyroid carcinoma
    • DOI 10.1056/NEJM199801293380506
    • M. J. Schlumberger, "Papillary and follicular thyroid carcinoma", New England Journal of Medicine, vol. 338, no. 5, pp. 297-306, 1998. (Pubitemid 28065257)
    • (1998) New England Journal of Medicine , vol.338 , Issue.5 , pp. 297-306
    • Schlumberger, M.J.1
  • 3
    • 0035177025 scopus 로고    scopus 로고
    • Immunohistochemical analysis of sodium iodide symporter expression in metastatic differentiated thyroid cancer: Correlation with radioiodine uptake
    • DOI 10.1210/jc.86.11.5627
    • M. R. Castro, E. R. Bergert, J. R. Goellner, I. D. Hay, and J. C. Morris, "Immunohistochemical analysis of sodium iodide symporter expression in metastatic differentiated thyroid cancer: correlation with radioiodine uptake", Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 11, pp. 5627-5632, 2001. (Pubitemid 33070298)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.11 , pp. 5627-5632
    • Castro, M.R.1    Bergert, E.R.2    Goellner, J.R.3    Hay, I.D.4    Morris, J.C.5
  • 4
    • 0141527592 scopus 로고    scopus 로고
    • Low expression of sodium iodide symporter identifies aggressive thyroid tumors
    • DOI 10.1016/S0304-3835(03)00392-6
    • L. S. Ward, P. L. Santarosa, F. Granja, L. V. M. Da Assumpçã o, M. Savoldi, and G. H. Goldman, "Low expression of sodium iodide symporter identifies aggressive thyroid tumors", Cancer Letters, vol. 200, no. 1, pp. 85-91, 2003. (Pubitemid 37222362)
    • (2003) Cancer Letters , vol.200 , Issue.1 , pp. 85-91
    • Ward, L.S.1    Santarosa, P.L.2    Granja, F.3    Da Assumpcao, L.V.M.4    Savoldi, M.5    Goldman, G.H.6
  • 5
    • 9444277283 scopus 로고    scopus 로고
    • How thyroid tumors start and why it matters: Kinase mutants as targets for solid cancer pharmacotherapy
    • DOI 10.1677/joe.1.05895
    • J. A. Fagin, "How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy", Journal of Endocrinology, vol. 183, no. 2, pp. 249-256, 2004. (Pubitemid 39562707)
    • (2004) Journal of Endocrinology , vol.183 , Issue.2 , pp. 249-256
    • Fagin, J.A.1
  • 7
    • 77954762933 scopus 로고    scopus 로고
    • Cytotoxic chemotherapy for differentiated thyroid carcinoma
    • S. I. Sherman, "Cytotoxic chemotherapy for differentiated thyroid carcinoma", Clinical Oncology, vol. 22, no. 6, pp. 464-468, 2010.
    • (2010) Clinical Oncology , vol.22 , Issue.6 , pp. 464-468
    • Sherman, S.I.1
  • 8
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • DOI 10.1677/erc.1.0978
    • M. Xing, "BRAF mutation in thyroid cancer", Endocrine-Related Cancer, vol. 12, no. 2, pp. 245-262, 2005. (Pubitemid 40896444)
    • (2005) Endocrine-Related Cancer , vol.12 , Issue.2 , pp. 245-262
    • Xing, M.1
  • 9
    • 33645069923 scopus 로고    scopus 로고
    • BRAF is a therapeutic target in aggressive thyroid carcinoma
    • G. Salvatore, V. De Falco, P. Salerno et al., "BRAF is a therapeutic target in aggressive thyroid carcinoma", Clinical Cancer Research, vol. 12, no. 5, pp. 1623-1629, 2006.
    • (2006) Clinical Cancer Research , vol.12 , Issue.5 , pp. 1623-1629
    • Salvatore, G.1    De Falco, V.2    Salerno, P.3
  • 10
    • 33645698808 scopus 로고    scopus 로고
    • Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo
    • B. Ouyang, J. A. Knauf, E. P. Smith et al., "Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo", Clinical Cancer Research, vol. 12, no. 6, pp. 1785-1793, 2006.
    • (2006) Clinical Cancer Research , vol.12 , Issue.6 , pp. 1785-1793
    • Ouyang, B.1    Knauf, J.A.2    Smith, E.P.3
  • 11
    • 76149087747 scopus 로고    scopus 로고
    • Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways
    • P. Hou, E. Bojdani, and M. Xing, "Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 2, pp. 820-828, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.2 , pp. 820-828
    • Hou, P.1    Bojdani, E.2    Xing, M.3
  • 12
    • 35348970378 scopus 로고    scopus 로고
    • Clinical, histopathological, and molecular characteristics of papillary thyroid microcarcinoma
    • D. J. Lim, K. H. Baek, Y. S. Lee et al., "Clinical, histopathological, and molecular characteristics of papillary thyroid microcarcinoma", Thyroid, vol. 17, no. 9, pp. 883-888, 2007.
    • (2007) Thyroid , vol.17 , Issue.9 , pp. 883-888
    • Lim, D.J.1    Baek, K.H.2    Lee, Y.S.3
  • 13
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer: Genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • E. T. Kimura, M. N. Nikiforova, Z. Zhu, J. A. Knauf, Y. E. Nikiforov, and J. A. Fagin, "High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma", Cancer Research, vol. 63, no. 7, pp. 1454-1457, 2003. (Pubitemid 36373628)
    • (2003) Cancer Research , vol.63 , Issue.7 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3    Knauf, J.A.4    Nikiforov, Y.E.5    Fagin, J.A.6
  • 17
    • 0030941779 scopus 로고    scopus 로고
    • Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children
    • Y. E. Nikiforov, J. M. Rowland, K. E. Bove, H. Monforte-Munoz, and J. A. Fagin, "Distinct pattern of ret oncogene rearrangements in morphological variants of radiationinduced and sporadic thyroid papillary carcinomas in children", Cancer Research, vol. 57, no. 9, pp. 1690-1694, 1997. (Pubitemid 27199660)
    • (1997) Cancer Research , vol.57 , Issue.9 , pp. 1690-1694
    • Nikiforov, Y.E.1    Rowland, J.M.2    Bove, K.E.3    Monforte-Munoz, H.4    Fagin, J.A.5
  • 18
    • 0031933680 scopus 로고    scopus 로고
    • RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes
    • G. Tallini, M. Santoro, M. Helie et al., "RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes", Clinical Cancer Research, vol. 4, no. 2, pp. 287-294, 1998. (Pubitemid 28122740)
    • (1998) Clinical Cancer Research , vol.4 , Issue.2 , pp. 287-294
    • Tallini, G.1    Santoro, M.2    Helie, M.3    Carlomagno, F.4    Salvatore, G.5    Chiappetta, G.6    Carcangiu, M.L.7    Fusco, A.8
  • 21
    • 33847072340 scopus 로고    scopus 로고
    • Minireview: RET/PTC rearrangements and braf mutations in thyroid tumorigenesis
    • R. Ciampi and Y. E. Nikiforov, "Minireview: RET/PTC rearrangements and braf mutations in thyroid tumorigenesis", Endocrinology, vol. 148, no. 3, pp. 936-941, 2007.
    • (2007) Endocrinology , vol.148 , Issue.3 , pp. 936-941
    • Ciampi, R.1    Nikiforov, Y.E.2
  • 24
    • 53749086690 scopus 로고    scopus 로고
    • BRAFV600E mutation and outcome of patients with papillary thyroid carcinoma: A 15-year median follow-up study
    • R. Elisei, C. Ugolini, D. Viola et al., "BRAFV600E mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study", Journal of Clinical Endocrinology and Metabolism, vol. 93, no. 10, pp. 3943-3949, 2008.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.10 , pp. 3943-3949
    • Elisei, R.1    Ugolini, C.2    Viola, D.3
  • 27
    • 0347363834 scopus 로고    scopus 로고
    • Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf
    • DOI 10.1038/sj.onc.1207185
    • T. Brummer, H. Naegele, M. Reth, and Y. Misawa, "Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf", Oncogene, vol. 22, no. 55, pp. 8823-8834, 2003. (Pubitemid 38021498)
    • (2003) Oncogene , vol.22 , Issue.55 , pp. 8823-8834
    • Brummer, T.1    Naegele, H.2    Reth, M.3    Misawa, Y.4
  • 30
    • 33644773510 scopus 로고    scopus 로고
    • Low frequency of BRAF mutations in adult patients with papillary thyroid cancers following childhood radiation exposure
    • DOI 10.1089/thy.2006.16.61
    • B. J. Collins, A. B. Schneider, R. A. Prinz, and X. Xu, "Low frequency of BRAF mutations in adult patients with papillary thyroid cancers following childhood radiation exposure", Thyroid, vol. 16, no. 1, pp. 61-66, 2006. (Pubitemid 43346505)
    • (2006) Thyroid , vol.16 , Issue.1 , pp. 61-66
    • Collins, B.J.1    Schneider, A.B.2    Prinz, R.A.3    Xu, X.4
  • 33
    • 33645232222 scopus 로고    scopus 로고
    • Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas
    • DOI 10.1097/01.pas.0000176432.73455.1b, PII 0000047820060200000010
    • A. J. Adeniran, Z. Zhu, M. Gandhi et al., "Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas", American Journal of Surgical Pathology, vol. 30, no. 2, pp. 216-222, 2006. (Pubitemid 43740191)
    • (2006) American Journal of Surgical Pathology , vol.30 , Issue.2 , pp. 216-222
    • Adeniran, A.J.1    Zhu, Z.2    Gandhi, M.3    Steward, D.L.4    Fidler, J.P.5    Giordano, T.J.6    Biddinger, P.W.7    Nikiforov, Y.E.8
  • 34
    • 16644384144 scopus 로고    scopus 로고
    • The BRAFT1796A transversion is a prevalent mutational event in human thyroid microcarcinoma
    • I. Sedliarou, V. Saenko, D. Lantsov et al., "The BRAFT1796A transversion is a prevalent mutational event in human thyroid microcarcinoma", International journal of oncology, vol. 25, no. 6, pp. 1729-1735, 2004.
    • (2004) International Journal of Oncology , vol.25 , Issue.6 , pp. 1729-1735
    • Sedliarou, I.1    Saenko, V.2    Lantsov, D.3
  • 35
    • 59449090715 scopus 로고    scopus 로고
    • Analysis of differential BRAFV600E mutational status in high aggressive papillary thyroid microcarcinoma
    • X. Lee, M. Gao, Y. Ji et al., "Analysis of differential BRAFV600E mutational status in high aggressive papillary thyroid microcarcinoma", Annals of Surgical Oncology, vol. 16, no. 2, pp. 240-245, 2009.
    • (2009) Annals of Surgical Oncology , vol.16 , Issue.2 , pp. 240-245
    • Lee, X.1    Gao, M.2    Ji, Y.3
  • 38
    • 18844437226 scopus 로고    scopus 로고
    • Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations
    • DOI 10.1002/cncr.21073
    • R. M. Quiros, H. G. Ding, P. Gattuso, R. A. Prinz, and X. Xu, "Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations", Cancer, vol. 103, no. 11, pp. 2261-2268, 2005. (Pubitemid 40686569)
    • (2005) Cancer , vol.103 , Issue.11 , pp. 2261-2268
    • Quiros, R.M.1    Ding, H.G.2    Gattuso, P.3    Prinz, R.A.4    Xu, X.5
  • 40
    • 33947290100 scopus 로고    scopus 로고
    • Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant
    • DOI 10.1158/1078-0432.CCR-06-1753
    • D. Liu, S. Hu, P. Hou, D. Jiang, S. Condouris, and M. Xing, "Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant", Clinical Cancer Research, vol. 13, no. 4, pp. 1341-1349, 2007. (Pubitemid 46424076)
    • (2007) Clinical Cancer Research , vol.13 , Issue.4 , pp. 1341-1349
    • Liu, D.1    Hu, S.2    Hou, P.3    Jiang, D.4    Condouris, S.5    Xing, M.6
  • 41
    • 70350554104 scopus 로고    scopus 로고
    • The BRAFV600E oncogene induces transforming growth factor β secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer
    • G. Riesco-Eizaguirre, I. Rodríguez, A. De La Vieja et al., "The BRAFV600E oncogene induces transforming growth factor β secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer", Cancer Research, vol. 69, no. 21, pp. 8317-8325, 2009.
    • (2009) Cancer Research , vol.69 , Issue.21 , pp. 8317-8325
    • Riesco-Eizaguirre, G.1    Rodríguez, I.2    De La Vieja, A.3
  • 42
    • 0027455042 scopus 로고
    • High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
    • J. A. Fagin, K. Matsuo, A. Karmakar, Dan Lin Chen, S. H. Tang, and H. P. Koeffler, "High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas", Journal of Clinical Investigation, vol. 91, no. 1, pp. 179-184, 1993. (Pubitemid 23037270)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.1 , pp. 179-184
    • Fagin, J.A.1    Matsuo, K.2    Karmakar, A.3    Dan Lin Chen4    Tang, S.-H.5    Koeffler, H.P.6
  • 43
    • 0035354187 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation
    • L. Ludwig, H. Kessler, M. Wagner et al., "Nuclear factor-?B is constitutively active in C-cell carcinoma and required for RET-induced transformation", Cancer Research, vol. 61, no. 11, pp. 4526-4535, 2001. (Pubitemid 32685784)
    • (2001) Cancer Research , vol.61 , Issue.11 , pp. 4526-4535
    • Ludwig, L.1    Kessler, H.2    Wagner, M.3    Hoang-Vu, C.4    Dralle, H.5    Adler, G.6    Bohm, B.O.7    Schmid, R.M.8
  • 44
    • 0030929178 scopus 로고    scopus 로고
    • High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation
    • A. Bounacer, R. Wicker, B. Caillou et al., "High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation", Oncogene, vol. 15, no. 11, pp. 1263-1273, 1997. (Pubitemid 27429741)
    • (1997) Oncogene , vol.15 , Issue.11 , pp. 1263-1273
    • Bounacer, A.1    Wicker, R.2    Caillou, B.3    Cailleux, A.F.4    Sarasin, A.5    Schlumberger, M.6    Suarez, H.G.7
  • 45
    • 0034453001 scopus 로고    scopus 로고
    • The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults
    • DOI 10.1210/jc.85.3.1170
    • C. L. Fenton, Y. Lukes, D. Nicholson, C. A. Dinauer, G. L. Francis, and R. M. Tuttle, "The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults", Journal of Clinical Endocrinology and Metabolism, vol. 85, no. 3, pp. 1170-1175, 2000. (Pubitemid 32269367)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.3 , pp. 1170-1175
    • Fenton, C.L.1    Lukes, Y.2    Nicholson, D.3    Dinauer, C.A.4    Francis, G.L.5    Tuttle, R.M.6
  • 49
    • 0036127871 scopus 로고    scopus 로고
    • Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas
    • M. N. Nikiforova, C. M. Caudill, P. Biddinger, and Y. E. Nikiforov, "Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas", International Journal of Surgical Pathology, vol. 10, no. 1, pp. 15-22, 2002. (Pubitemid 34245954)
    • (2002) International Journal of Surgical Pathology , vol.10 , Issue.1 , pp. 15-22
    • Nikiforova, M.N.1    Caudill, C.M.2    Biddinger, P.3    Nikiforov, Y.E.4
  • 50
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • DOI 10.1038/nature04483, PII NATURE04483
    • N. Ferrara and R. S. Kerbel, "Angiogenesis as a therapeutic target", Nature, vol. 438, no. 7070, pp. 967-974, 2005. (Pubitemid 43093963)
    • (2005) Nature , vol.438 , Issue.7070 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 52
    • 0035034282 scopus 로고    scopus 로고
    • Intensity of vascular endothelial growth factor expression is associated with increased risk of recurrence and decreased disease-free survival in papillary thyroid cancer
    • DOI 10.1067/msy.2001.112592
    • C. M. Lennard, A. Patel, J. Wilson et al., "Intensity of vascular endothelial growth factor expression is associated with increased risk of recurrence and decreased disease-free survival in papillary thyroid cancer", Surgery, vol. 129, no. 5, pp. 552-558, 2001. (Pubitemid 32374986)
    • (2001) Surgery , vol.129 , Issue.5 , pp. 552-558
    • Lennard, C.M.1    Patel, A.2    Wilson, J.3    Reinhardt, B.4    Tuman, C.5    Fenton, C.6    Blair, E.7    Francis, G.L.8    Tuttle, R.M.9
  • 53
    • 0032775391 scopus 로고    scopus 로고
    • PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation
    • DOI 10.1016/S0378-1119(99)00206-1, PII S0378111999002061
    • A. K. Ghosh, I. Grigorieva, R. Steele, R. G. Hoover, and R. B. Ray, "PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation", Gene, vol. 235, no. 1-2, pp. 85-91, 1999. (Pubitemid 29327286)
    • (1999) Gene , vol.235 , Issue.1-2 , pp. 85-91
    • Ghosh, A.K.1    Grigorieva, I.2    Steele, R.3    Hoover, R.G.4    Ray, R.B.5
  • 54
    • 0033575287 scopus 로고    scopus 로고
    • PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway
    • M. Tamura, J. Gu, E. H. J. Danen, T. Takino, S. Miyamoto, and K. M. Yamada, "PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway", Journal of Biological Chemistry, vol. 274, no. 29, pp. 20693-20703, 1999.
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.29 , pp. 20693-20703
    • Tamura, M.1    Gu, J.2    Danen, E.H.J.3    Takino, T.4    Miyamoto, S.5    Yamada, K.M.6
  • 56
    • 0037431435 scopus 로고    scopus 로고
    • Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma
    • DOI 10.1002/ijc.10962
    • D. S. Byun, K. Cho, B. K. Ryu et al., "Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma", International Journal of Cancer, vol. 104, no. 3, pp. 318-327, 2003. (Pubitemid 36249814)
    • (2003) International Journal of Cancer , vol.104 , Issue.3 , pp. 318-327
    • Byun, D.-S.1    Cho, K.2    Ryu, B.-K.3    Lee, M.-G.4    Park, J.-I.5    Chae, K.-S.6    Kim, H.-J.7    Chi, S.-G.8
  • 59
  • 60
    • 0033200172 scopus 로고    scopus 로고
    • Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
    • M. E. McMenamin, P. Soung, S. Perera, I. Kaplan, M. Loda, and W. R. Sellers, "Loss of PTEN expression in paraffinembedded primary prostate cancer correlates with high Gleason score and advanced stage", Cancer Research, vol. 59, no. 17, pp. 4291-4296, 1999. (Pubitemid 29418745)
    • (1999) Cancer Research , vol.59 , Issue.17 , pp. 4291-4296
    • McMenamin, M.E.1    Soung, P.2    Perera, S.3    Kaplan, I.4    Loda, M.5    Sellers, W.R.6
  • 61
    • 55549084534 scopus 로고    scopus 로고
    • Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors
    • P. Hou, M. Ji, and M. Xing, "Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors", Cancer, vol. 113, no. 9, pp. 2440-2447, 2008.
    • (2008) Cancer , vol.113 , Issue.9 , pp. 2440-2447
    • Hou, P.1    Ji, M.2    Xing, M.3
  • 64
    • 51049092292 scopus 로고    scopus 로고
    • Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement
    • Y. C. Henderson, S. H. Ann, Y. Kang, and G. L. Clayman, "Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement", Clinical Cancer Research, vol. 14, no. 15, pp. 4908-4914, 2008.
    • (2008) Clinical Cancer Research , vol.14 , Issue.15 , pp. 4908-4914
    • Henderson, Y.C.1    Ann, S.H.2    Kang, Y.3    Clayman, G.L.4
  • 65
    • 34247857540 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: A review of four phase I trials in patients with advanced refractory solid tumors
    • DOI 10.1634/theoncologist.12-4-426
    • D. Strumberg, J. W. Clark, A. Awada et al., "Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors", Oncologist, vol. 12, no. 4, pp. 426-437, 2007. (Pubitemid 46698720)
    • (2007) Oncologist , vol.12 , Issue.4 , pp. 426-437
    • Strumberg, D.1    Clark, J.W.2    Awada, A.3    Moore, M.J.4    Richly, H.5    Hendlisz, A.6    Hirte, H.W.7    Eder, J.P.8    Lenz, H.-J.9    Schwartzh, B.10
  • 66
    • 50649095250 scopus 로고    scopus 로고
    • Phase II trial of sorafenib in advanced thyroid cancer
    • V. Gupta-Abramson, A. B. Troxel, A. Nellore et al., "Phase II trial of sorafenib in advanced thyroid cancer", Journal of Clinical Oncology, vol. 26, no. 29, pp. 4714-4719, 2008.
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.29 , pp. 4714-4719
    • Gupta-Abramson, V.1    Troxel, A.B.2    Nellore, A.3
  • 67
    • 63849265332 scopus 로고    scopus 로고
    • Phase II trial of sorafenib in metastatic thyroid cancer
    • R. T. Kloos, M. D. Ringel, M. V. Knopp et al., "Phase II trial of sorafenib in metastatic thyroid cancer", Journal of Clinical Oncology, vol. 27, no. 10, pp. 1675-1684, 2009.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.10 , pp. 1675-1684
    • Kloos, R.T.1    Ringel, M.D.2    Knopp, M.V.3
  • 68
    • 72949106263 scopus 로고    scopus 로고
    • Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma
    • H. Hoftijzer, K. A. Heemstra, H. Morreau et al., "Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma", European Journal of Endocrinology, vol. 161, no. 6, pp. 923-931, 2009.
    • (2009) European Journal of Endocrinology , vol.161 , Issue.6 , pp. 923-931
    • Hoftijzer, H.1    Heemstra, K.A.2    Morreau, H.3
  • 69
    • 77954476036 scopus 로고    scopus 로고
    • Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: The M. D. Anderson experience
    • M. E. Cabanillas, S. G. Waguespack, Y. Bronstein et al., "Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 6, pp. 2588-2595, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.6 , pp. 2588-2595
    • Cabanillas, M.E.1    Waguespack, S.G.2    Bronstein, Y.3
  • 70
    • 77952468875 scopus 로고    scopus 로고
    • Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer
    • E. T. Lam, M. D. Ringel, R. T. Kloos et al., "Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer", Journal of Clinical Oncology, vol. 28, no. 14, pp. 2323-2330, 2010.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.14 , pp. 2323-2330
    • Lam, E.T.1    Ringel, M.D.2    Kloos, R.T.3
  • 71
    • 55949123335 scopus 로고    scopus 로고
    • Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
    • M. Schmidinger, C. C. Zielinski, U. M. Vogl et al., "Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma", Journal of Clinical Oncology, vol. 26, no. 32, pp. 5204-5212, 2008.
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.32 , pp. 5204-5212
    • Schmidinger, M.1    Zielinski, C.C.2    Vogl, U.M.3
  • 72
    • 70450224682 scopus 로고    scopus 로고
    • Sorafenib-induced acute myocardial infarction due to coronary artery spasm
    • Y. Arima, S. Oshima, K. Noda et al., "Sorafenib-induced acute myocardial infarction due to coronary artery spasm", Journal of Cardiology, vol. 54, no. 3, pp. 512-515, 2009.
    • (2009) Journal of Cardiology , vol.54 , Issue.3 , pp. 512-515
    • Arima, Y.1    Oshima, S.2    Noda, K.3
  • 73
    • 68949094219 scopus 로고    scopus 로고
    • Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib
    • J. P. Arnault, J. Wechsler, B. Escudier et al., "Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib", Journal of Clinical Oncology, vol. 27, no. 23, pp. e59-e61, 2009.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.23
    • Arnault, J.P.1    Wechsler, J.2    Escudier, B.3
  • 74
    • 77956513286 scopus 로고    scopus 로고
    • Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
    • G. Bollag, P. Hirth, J. Tsai et al., "Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma", Nature, vol. 467, no. 7315, pp. 596-599, 2010.
    • (2010) Nature , vol.467 , Issue.7315 , pp. 596-599
    • Bollag, G.1    Hirth, P.2    Tsai, J.3
  • 76
    • 75149188152 scopus 로고    scopus 로고
    • Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells
    • P. Salerno, V. De Falco, A. Tamburrino et al., "Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 1, pp. 450-455, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.1 , pp. 450-455
    • Salerno, P.1    De Falco, V.2    Tamburrino, A.3
  • 77
    • 47249097988 scopus 로고    scopus 로고
    • BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells
    • E. Sala, L. Mologni, S. Truffa, C. Gaetano, G. E. Bollag, and C. Gambacorti-Passerini, "BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells", Molecular Cancer Research, vol. 6, no. 5, pp. 751-759, 2008.
    • (2008) Molecular Cancer Research , vol.6 , Issue.5 , pp. 751-759
    • Sala, E.1    Mologni, L.2    Truffa, S.3    Gaetano, C.4    Bollag, G.E.5    Gambacorti-Passerini, C.6
  • 78
    • 77950954465 scopus 로고    scopus 로고
    • Differential sensitivity of melanoma cell lines with BRAFV600Emutation to the specific Raf inhibitor PLX4032
    • J. N. Søndergaard, R. Nazarian, Q. Wang et al., "Differential sensitivity of melanoma cell lines with BRAFV600Emutation to the specific Raf inhibitor PLX4032", Journal of Translational Medicine, vol. 8, article 39, 2010.
    • (2010) Journal of Translational Medicine , vol.8 , pp. 39
    • Søndergaard, J.N.1    Nazarian, R.2    Wang, Q.3
  • 79
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • K. T. Flaherty, I. Puzanov, K. B. Kim et al., "Inhibition of mutated, activated BRAF in metastatic melanoma", New England Journal of Medicine, vol. 363, no. 9, pp. 809-819, 2010.
    • (2010) New England Journal of Medicine , vol.363 , Issue.9 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 80
    • 68949106943 scopus 로고    scopus 로고
    • A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients with advanced solid tumors
    • G. K. Schwartz, S. Robertson, A. Shen et al., "A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients with advanced solid tumors", Journal of Clinical Oncology, vol. 27, no. 15s, abstract 3513, 2009.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.15 S , pp. 3513
    • Schwartz, G.K.1    Robertson, S.2    Shen, A.3
  • 82
    • 65749087602 scopus 로고    scopus 로고
    • Phase II study of sunitinib in refractory thyroid cancer
    • E. E. W. Cohen, B. M. Needles, K. J. Cullen et al., "Phase II study of sunitinib in refractory thyroid cancer", Journal of Clinical Oncology, vol. 26, abstract 6025, 2008.
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 6025
    • Cohen, E.E.W.1    Needles, B.M.2    Cullen, K.J.3
  • 83
    • 75449104629 scopus 로고    scopus 로고
    • A case of advanced medullary thyroid carcinoma successfully treated with sunitinib
    • M. J. Bugalho, R. Domingues, and A. Borges, "A case of advanced medullary thyroid carcinoma successfully treated with sunitinib", Oncologist, vol. 14, no. 11, pp. 1083-1087, 2009.
    • (2009) Oncologist , vol.14 , Issue.11 , pp. 1083-1087
    • Bugalho, M.J.1    Domingues, R.2    Borges, A.3
  • 85
    • 34248632840 scopus 로고    scopus 로고
    • Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity
    • DOI 10.1089/thy.2006.0308
    • E. Wong, L. S. Rosen, M. Mulay et al., "Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity", Thyroid, vol. 17, no. 4, pp. 351-355, 2007. (Pubitemid 46776140)
    • (2007) Thyroid , vol.17 , Issue.4 , pp. 351-355
    • Wong, E.1    Rosen, L.S.2    Mulay, M.3    VanVugt, A.4    Dinolfo, M.5    Tomoda, C.6    Sugawara, M.7    Hershman, J.M.8
  • 86
    • 77957366667 scopus 로고    scopus 로고
    • Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer
    • M. B. Bass, S. I. Sherman, M. J. Schlumberger et al., "Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 11, pp. 5018-5027, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.11 , pp. 5018-5027
    • Bass, M.B.1    Sherman, S.I.2    Schlumberger, M.J.3
  • 88
    • 78651361788 scopus 로고    scopus 로고
    • Hypothyroidism in patients with renal cell carcinoma: Blessing or curse?
    • M. Schmidinger, U. M. Vogl, M. Bojic et al., "Hypothyroidism in patients with renal cell carcinoma: blessing or curse?" Cancer, vol. 117, no. 3, pp. 534-544, 2011.
    • (2011) Cancer , vol.117 , Issue.3 , pp. 534-544
    • Schmidinger, M.1    Vogl, U.M.2    Bojic, M.3
  • 90
    • 77958194741 scopus 로고    scopus 로고
    • The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro
    • B. B. Hasinoff and D. Patel, "The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro", Toxicology and Applied Pharmacology, vol. 249, no. 2, pp. 132-139, 2010.
    • (2010) Toxicology and Applied Pharmacology , vol.249 , Issue.2 , pp. 132-139
    • Hasinoff, B.B.1    Patel, D.2
  • 91
    • 50949132320 scopus 로고    scopus 로고
    • Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics
    • M. H. Chen, R. Kerkelä, and T. Force, "Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics", Circulation, vol. 118, no. 1, pp. 84-95, 2008.
    • (2008) Circulation , vol.118 , Issue.1 , pp. 84-95
    • Chen, M.H.1    Kerkelä, R.2    Force, T.3
  • 92
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
    • S. R. Wedge, D. J. Ogilvie, M. Dukes et al., "ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration", Cancer Research, vol. 62, no. 16, pp. 4645-4655, 2002.
    • (2002) Cancer Research , vol.62 , Issue.16 , pp. 4645-4655
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3
  • 94
    • 33846850223 scopus 로고    scopus 로고
    • Vandetanib (ZD6474): An orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis
    • DOI 10.1517/13543784.16.2.239
    • R. S. Herbst, J. V. Heymach, M. S. O'Reilly, A. Onn, and A. J. Ryan, "Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis", Expert Opinion on Investigational Drugs, vol. 16, no. 2, pp. 239-249, 2007. (Pubitemid 46206638)
    • (2007) Expert Opinion on Investigational Drugs , vol.16 , Issue.2 , pp. 239-249
    • Herbst, R.S.1    Heymach, J.V.2    O'Reilly, M.S.3    Onn, A.4    Ryan, A.J.5
  • 96
    • 79251531655 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells
    • D. Vitagliano, V. De Falco, A. Tamburrino et al., "The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells", Endocrine-Related Cancer, vol. 18, no. 1, pp. 1-11, 2011.
    • (2011) Endocrine-Related Cancer , vol.18 , Issue.1 , pp. 1-11
    • Vitagliano, D.1    De Falco, V.2    Tamburrino, A.3
  • 97
    • 77649214078 scopus 로고    scopus 로고
    • Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer
    • S. A. Wells Jr., J. E. Gosnell, R. F. Gagel et al., "Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer", Journal of Clinical Oncology, vol. 28, no. 5, pp. 767-772, 2010.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.5 , pp. 767-772
    • Wells Jr., S.A.1    Gosnell, J.E.2    Gagel, R.F.3
  • 99
    • 77954478933 scopus 로고    scopus 로고
    • Vandetanib (100 mg) in patients with locally advanced or metastatic hereditary medullary thyroid cancer
    • B. G. Robinson, L. Paz-Ares, A. Krebs, J. Vasselli, and R. Haddad, "Vandetanib (100 mg) in patients with locally advanced or metastatic hereditary medullary thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 6, pp. 2664-2671, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.6 , pp. 2664-2671
    • Robinson, B.G.1    Paz-Ares, L.2    Krebs, A.3    Vasselli, J.4    Haddad, R.5
  • 100
  • 101
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • M. Carroll, S. Ohno-Jones, S. Tamura et al., "CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins", Blood, vol. 90, no. 12, pp. 4947-4952, 1997. (Pubitemid 28007210)
    • (1997) Blood , vol.90 , Issue.12 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3    Buchdunger, E.4    Zimmermann, J.5    Lydon, N.B.6    Gilliland, D.G.7    Druker, B.J.8
  • 103
    • 2442423952 scopus 로고    scopus 로고
    • Imatinib Mesylate (Gleevec; STI571) Monotherapy Is Ineffective in Suppressing Human Anaplastic Thyroid Carcinoma Cell Growth in Vitro
    • DOI 10.1210/jc.2003-031734
    • J. M. Dziba and K. B. Ain, "Imatinib mesylate (Gleevec; STI571) monotherapy is ineffective in suppressing human anaplastic thyroid carcinoma cell growth in vitro", Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 5, pp. 2127-2135, 2004. (Pubitemid 38619841)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.5 , pp. 2127-2135
    • Dziba, J.M.1    Ain, K.B.2
  • 105
    • 34547801152 scopus 로고    scopus 로고
    • Efficacy of imatinib mesylate in advanced medullary thyroid carcinoma
    • DOI 10.1530/EJE-06-0695
    • K. Frank-Raue, M. Fabel, S. Delorme, U. Haberkorn, and F. Raue, "Efficacy of imatinib mesylate in advanced medullary thyroid carcinoma", European Journal of Endocrinology, vol. 157, no. 2, pp. 215-220, 2007. (Pubitemid 47233127)
    • (2007) European Journal of Endocrinology , vol.157 , Issue.2 , pp. 215-220
    • Frank-Raue, K.1    Fabel, M.2    Delorme, S.3    Haberkorn, U.4    Raue, F.5
  • 106
    • 78649958734 scopus 로고    scopus 로고
    • A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo
    • A. K. Samadi, R. Mukerji, A. Shah, B. N. Timmermann, and M. S. Cohen, "A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo", Surgery, vol. 148, no. 6, pp. 1228-1236, 2010.
    • (2010) Surgery , vol.148 , Issue.6 , pp. 1228-1236
    • Samadi, A.K.1    Mukerji, R.2    Shah, A.3    Timmermann, B.N.4    Cohen, M.S.5
  • 108
    • 78751501299 scopus 로고    scopus 로고
    • Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis
    • B. Gril, D. Palmieri, Y. Qian et al., "Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis", Clinical Cancer Research, vol. 17, no. 1, pp. 142-153, 2011.
    • (2011) Clinical Cancer Research , vol.17 , Issue.1 , pp. 142-153
    • Gril, B.1    Palmieri, D.2    Qian, Y.3
  • 109
    • 77956649079 scopus 로고    scopus 로고
    • A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer
    • M. Friedlander, K. C. Hancock, D. Rischin et al., "A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer", Gynecologic Oncology, vol. 119, no. 1, pp. 32-37, 2010.
    • (2010) Gynecologic Oncology , vol.119 , Issue.1 , pp. 32-37
    • Friedlander, M.1    Hancock, K.C.2    Rischin, D.3
  • 110
    • 77955503066 scopus 로고    scopus 로고
    • Phase II proof-of concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer
    • N. Altorki, M. E. Lane, T. Bauer et al., "Phase II proof-of concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer", Journal of Clinical Oncology, vol. 28, no. 19, pp. 3131-3137, 2010.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.19 , pp. 3131-3137
    • Altorki, N.1    Lane, M.E.2    Bauer, T.3
  • 111
    • 78650387508 scopus 로고    scopus 로고
    • Pazopanib in renal cell carcinoma
    • J. E. Ward and W. M. Stadler, "Pazopanib in renal cell carcinoma", Clinical Cancer Research, vol. 16, no. 24, pp. 5923-5927, 2010.
    • (2010) Clinical Cancer Research , vol.16 , Issue.24 , pp. 5923-5927
    • Ward, J.E.1    Stadler, W.M.2
  • 112
    • 77957359933 scopus 로고    scopus 로고
    • Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: Results of a phase 2 consortium study
    • K. C. Bible, V. J. Suman, J. R. Molina et al., "Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study", The Lancet Oncology, vol. 11, no. 10, pp. 962-972, 2010.
    • (2010) The Lancet Oncology , vol.11 , Issue.10 , pp. 962-972
    • Bible, K.C.1    Suman, V.J.2    Molina, J.R.3
  • 116
    • 68949108390 scopus 로고    scopus 로고
    • Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer
    • M. J. Schlumberger, R. Elisei, L. Bastholt et al., "Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer", Journal of Clinical Oncology, vol. 27, no. 23, pp. 3794-3801, 2009.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.23 , pp. 3794-3801
    • Schlumberger, M.J.1    Elisei, R.2    Bastholt, L.3
  • 117
    • 77957366667 scopus 로고    scopus 로고
    • Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer
    • M. B. Bass, S. I. Sherman, M. J. Schlumberger et al., "Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 11, pp. 5018-5027, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.11 , pp. 5018-5027
    • Bass, M.B.1    Sherman, S.I.2    Schlumberger, M.J.3
  • 118
    • 24944453855 scopus 로고    scopus 로고
    • Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: Pharmacokinetic and clinical results
    • H. S. Rugo, R. S. Herbst, G. Liu et al., "Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results", Journal of Clinical Oncology, vol. 23, no. 24, pp. 5474-5483, 2005.
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.24 , pp. 5474-5483
    • Rugo, H.S.1    Herbst, R.S.2    Liu, G.3
  • 119
    • 50649095801 scopus 로고    scopus 로고
    • Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: Results from a phase II study
    • E. E. W. Cohen, L. S. Rosen, E. E. Vokes et al., "Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study", Journal of Clinical Oncology, vol. 26, no. 29, pp. 4708-4713, 2008.
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.29 , pp. 4708-4713
    • Cohen, E.E.W.1    Rosen, L.S.2    Vokes, E.E.3
  • 120
    • 4344644698 scopus 로고    scopus 로고
    • Activation of the Hepatocyte Growth Factor (HGF)-Met system in papillary thyroid cancer: Biological effects of HGF in thyroid cancer cells depend on Met expression levels
    • DOI 10.1210/en.2003-1762
    • R. Mineo, A. Costantino, F. Frasca et al., "Activation of the Hepatocyte Growth Factor (HGF)-Met system in papillary thyroid cancer: biological effects of HGF in thyroid cancer cells depend on Met expression levels", Endocrinology, vol. 145, no. 9, pp. 4355-4365, 2004. (Pubitemid 39120585)
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4355-4365
    • Mineo, R.1    Costantino, A.2    Frasca, F.3    Sciacca, L.4    Russo, S.5    Vigneri, R.6    Belfiore, A.7
  • 121
    • 77952930543 scopus 로고    scopus 로고
    • A Phase I study of XL184, a MET, VEGFR2, and RET kinase inhibitor, administered orally to patients with advanced malignancies, including a subgroup of patients with medullary thyroid carcinoma
    • Geneva, Switzerland, October, poster number 379
    • R. Kurzrock, S. Sherman, D. Hong et al., "A Phase I study of XL184, a MET, VEGFR2, and RET kinase inhibitor, administered orally to patients with advanced malignancies, including a subgroup of patients with medullary thyroid carcinoma", in the EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics, Geneva, Switzerland, October 2008, poster number 379.
    • (2008) The EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics
    • Kurzrock, R.1    Sherman, S.2    Hong, D.3
  • 122
    • 79951709994 scopus 로고    scopus 로고
    • Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer
    • A. Antonelli, G. Bocci, C. La Motta et al., "Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 96, no. 2, pp. E288-E296, 2011.
    • (2011) Journal of Clinical Endocrinology and Metabolism , vol.96 , Issue.2
    • Antonelli, A.1    Bocci, G.2    La Motta, C.3
  • 124
    • 77954219743 scopus 로고    scopus 로고
    • Targeted therapy of thyroid cancer
    • S. I. Sherman, "Targeted therapy of thyroid cancer", Biochemical Pharmacology, vol. 80, no. 5, pp. 592-601, 2010.
    • (2010) Biochemical Pharmacology , vol.80 , Issue.5 , pp. 592-601
    • Sherman, S.I.1
  • 125
    • 77954503387 scopus 로고    scopus 로고
    • Harvesting the low-hanging fruit: Kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer
    • J. A. Fagin, R. M. Tuttle, and D. G. Pfister, "Harvesting the low-hanging fruit: kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 6, pp. 2621-2624, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.6 , pp. 2621-2624
    • Fagin, J.A.1    Tuttle, R.M.2    Pfister, D.G.3
  • 126
    • 2542458413 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin
    • DOI 10.1210/en.2003-1258
    • F. Furuya, H. Shimura, H. Suzuki et al., "Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin", Endocrinology, vol. 145, no. 6, pp. 2865-2875, 2004. (Pubitemid 38686236)
    • (2004) Endocrinology , vol.145 , Issue.6 , pp. 2865-2875
    • Furuya, F.1    Shimura, H.2    Suzuki, H.3    Taki, K.4    Ohta, K.5    Haraguchi, K.6    Onaya, T.7    Endo, T.8    Kobayashi, T.9
  • 127
    • 58149387609 scopus 로고    scopus 로고
    • Lack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with metastatic radioiodine-refractory thyroid carcinoma
    • J. A. Woyach, R. T. Kloos, M. D. Ringel et al., "Lack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with
    • (2009) Journal of Clinical Endocrinology and Metabolism , vol.94 , Issue.1 , pp. 164-170
    • Woyach, J.A.1    Kloos, R.T.2    Ringel, M.D.3
  • 128
    • 2542458413 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin
    • DOI 10.1210/en.2003-1258
    • F. Furuya, H. Shimura, H. Suzuki et al., "Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin", Endocrinology, vol. 145, no. 6, pp. 2865-2875, 2004. (Pubitemid 38686236)
    • (2004) Endocrinology , vol.145 , Issue.6 , pp. 2865-2875
    • Furuya, F.1    Shimura, H.2    Suzuki, H.3    Taki, K.4    Ohta, K.5    Haraguchi, K.6    Onaya, T.7    Endo, T.8    Kobayashi, T.9
  • 129
    • 76149087747 scopus 로고    scopus 로고
    • Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways
    • P. Hou, E. Bojdani, and M. Xing, "Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 2, pp. 820-828, 2010.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , Issue.2 , pp. 820-828
    • Hou, P.1    Bojdani, E.2    Xing, M.3
  • 131
    • 67649910150 scopus 로고    scopus 로고
    • Pilot trial of autologous dendritic cells loaded with tumor lysate (s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma
    • T. Bachleitner-Hofmann, J. Friedl, M. Hassler et al., "Pilot trial of autologous dendritic cells loaded with tumor lysate (s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma", Oncology Reports, vol. 21, no. 6, pp. 1585-1592, 2009.
    • (2009) Oncology Reports , vol.21 , Issue.6 , pp. 1585-1592
    • Bachleitner-Hofmann, T.1    Friedl, J.2    Hassler, M.3
  • 132
    • 34247362027 scopus 로고    scopus 로고
    • Methods and goals for the use of in vitro and in vivo chemosensitivity testing
    • DOI 10.1007/s12033-007-9020-9, PII MB352185
    • R. D. Blumenthal and D. M. Goldenberg, "Methods and goals for the use of in vitro and in vivo chemosensitivity testing", Molecular Biotechnology, vol. 35, no. 2, pp. 185-197, 2007. (Pubitemid 46631888)
    • (2007) Molecular Biotechnology , vol.35 , Issue.2 , pp. 185-197
    • Blumenthal, R.D.1    Goldenberg, D.M.2
  • 133
    • 77954744653 scopus 로고    scopus 로고
    • Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors
    • T. J. Kruser, D. L. Wheeler, E. A. Armstrong et al., "Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors", Clinical Cancer Research, vol. 16, no. 14, pp. 3639-3647, 2010.
    • (2010) Clinical Cancer Research , vol.16 , Issue.14 , pp. 3639-3647
    • Kruser, T.J.1    Wheeler, D.L.2    Armstrong, E.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.