-
1
-
-
79951996318
-
Surveillance, epidemiology, and end results (S. E. E. R. Program)
-
December
-
"Surveillance, Epidemiology, and End Results (S. E. E. R. Program)", Generate custom reports from the cancer statistics review, Seer 9:1975-2007, December 2010, http://seer.cancer.gov/.
-
(2010)
Generate Custom Reports from the Cancer Statistics Review, Seer
, vol.9
, pp. 1975-2007
-
-
-
2
-
-
0032576677
-
Papillary and follicular thyroid carcinoma
-
DOI 10.1056/NEJM199801293380506
-
M. J. Schlumberger, "Papillary and follicular thyroid carcinoma", New England Journal of Medicine, vol. 338, no. 5, pp. 297-306, 1998. (Pubitemid 28065257)
-
(1998)
New England Journal of Medicine
, vol.338
, Issue.5
, pp. 297-306
-
-
Schlumberger, M.J.1
-
3
-
-
0035177025
-
Immunohistochemical analysis of sodium iodide symporter expression in metastatic differentiated thyroid cancer: Correlation with radioiodine uptake
-
DOI 10.1210/jc.86.11.5627
-
M. R. Castro, E. R. Bergert, J. R. Goellner, I. D. Hay, and J. C. Morris, "Immunohistochemical analysis of sodium iodide symporter expression in metastatic differentiated thyroid cancer: correlation with radioiodine uptake", Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 11, pp. 5627-5632, 2001. (Pubitemid 33070298)
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, Issue.11
, pp. 5627-5632
-
-
Castro, M.R.1
Bergert, E.R.2
Goellner, J.R.3
Hay, I.D.4
Morris, J.C.5
-
4
-
-
0141527592
-
Low expression of sodium iodide symporter identifies aggressive thyroid tumors
-
DOI 10.1016/S0304-3835(03)00392-6
-
L. S. Ward, P. L. Santarosa, F. Granja, L. V. M. Da Assumpçã o, M. Savoldi, and G. H. Goldman, "Low expression of sodium iodide symporter identifies aggressive thyroid tumors", Cancer Letters, vol. 200, no. 1, pp. 85-91, 2003. (Pubitemid 37222362)
-
(2003)
Cancer Letters
, vol.200
, Issue.1
, pp. 85-91
-
-
Ward, L.S.1
Santarosa, P.L.2
Granja, F.3
Da Assumpcao, L.V.M.4
Savoldi, M.5
Goldman, G.H.6
-
5
-
-
9444277283
-
How thyroid tumors start and why it matters: Kinase mutants as targets for solid cancer pharmacotherapy
-
DOI 10.1677/joe.1.05895
-
J. A. Fagin, "How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy", Journal of Endocrinology, vol. 183, no. 2, pp. 249-256, 2004. (Pubitemid 39562707)
-
(2004)
Journal of Endocrinology
, vol.183
, Issue.2
, pp. 249-256
-
-
Fagin, J.A.1
-
6
-
-
0038369070
-
Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer
-
DOI 10.1210/jc.2002-021713
-
C. Scollo, E. Baudin, J. P. Travagli et al., "Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 5, pp. 2070-2075, 2003. (Pubitemid 36549878)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.5
, pp. 2070-2075
-
-
Scollo, C.1
Baudin, E.2
Travagli, J.-P.3
Caillou, B.4
Bellon, N.5
Leboulleux, S.6
Schlumberger, M.7
-
7
-
-
77954762933
-
Cytotoxic chemotherapy for differentiated thyroid carcinoma
-
S. I. Sherman, "Cytotoxic chemotherapy for differentiated thyroid carcinoma", Clinical Oncology, vol. 22, no. 6, pp. 464-468, 2010.
-
(2010)
Clinical Oncology
, vol.22
, Issue.6
, pp. 464-468
-
-
Sherman, S.I.1
-
8
-
-
21244457181
-
BRAF mutation in thyroid cancer
-
DOI 10.1677/erc.1.0978
-
M. Xing, "BRAF mutation in thyroid cancer", Endocrine-Related Cancer, vol. 12, no. 2, pp. 245-262, 2005. (Pubitemid 40896444)
-
(2005)
Endocrine-Related Cancer
, vol.12
, Issue.2
, pp. 245-262
-
-
Xing, M.1
-
9
-
-
33645069923
-
BRAF is a therapeutic target in aggressive thyroid carcinoma
-
G. Salvatore, V. De Falco, P. Salerno et al., "BRAF is a therapeutic target in aggressive thyroid carcinoma", Clinical Cancer Research, vol. 12, no. 5, pp. 1623-1629, 2006.
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.5
, pp. 1623-1629
-
-
Salvatore, G.1
De Falco, V.2
Salerno, P.3
-
10
-
-
33645698808
-
Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo
-
B. Ouyang, J. A. Knauf, E. P. Smith et al., "Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo", Clinical Cancer Research, vol. 12, no. 6, pp. 1785-1793, 2006.
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.6
, pp. 1785-1793
-
-
Ouyang, B.1
Knauf, J.A.2
Smith, E.P.3
-
11
-
-
76149087747
-
Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways
-
P. Hou, E. Bojdani, and M. Xing, "Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 2, pp. 820-828, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.2
, pp. 820-828
-
-
Hou, P.1
Bojdani, E.2
Xing, M.3
-
12
-
-
35348970378
-
Clinical, histopathological, and molecular characteristics of papillary thyroid microcarcinoma
-
D. J. Lim, K. H. Baek, Y. S. Lee et al., "Clinical, histopathological, and molecular characteristics of papillary thyroid microcarcinoma", Thyroid, vol. 17, no. 9, pp. 883-888, 2007.
-
(2007)
Thyroid
, vol.17
, Issue.9
, pp. 883-888
-
-
Lim, D.J.1
Baek, K.H.2
Lee, Y.S.3
-
13
-
-
0037379904
-
High prevalence of BRAF mutations in thyroid cancer: Genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
-
E. T. Kimura, M. N. Nikiforova, Z. Zhu, J. A. Knauf, Y. E. Nikiforov, and J. A. Fagin, "High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma", Cancer Research, vol. 63, no. 7, pp. 1454-1457, 2003. (Pubitemid 36373628)
-
(2003)
Cancer Research
, vol.63
, Issue.7
, pp. 1454-1457
-
-
Kimura, E.T.1
Nikiforova, M.N.2
Zhu, Z.3
Knauf, J.A.4
Nikiforov, Y.E.5
Fagin, J.A.6
-
14
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
DOI 10.1016/S0092-8674(04)00215-6, PII S0092867404002156
-
P. T. C. Wan, M. J. Garnett, S. M. Roe et al., "Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF", Cell, vol. 116, no. 6, pp. 855-867, 2004. (Pubitemid 38410730)
-
(2004)
Cell
, vol.116
, Issue.6
, pp. 855-867
-
-
Wan, P.T.C.1
Garnett, M.J.2
Roe, S.M.3
Lee, S.4
Niculescu-Duvaz, D.5
Good, V.M.6
Project, C.G.7
Jones, C.M.8
Marshall, C.J.9
Springer, C.J.10
Barford, D.11
Marais, R.12
-
15
-
-
33947284529
-
Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer
-
DOI 10.1158/1078-0432.CCR-06-1125
-
P. Hou, D. Liu, Y. Shan et al., "Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer", Clinical Cancer Research, vol. 13, no. 4, pp. 1161-1170, 2007. (Pubitemid 46424056)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1161-1170
-
-
Hou, P.1
Liu, D.2
Shan, Y.3
Hu, S.4
Studeman, K.5
Condouris, S.6
Wang, Y.7
Trink, A.8
El-Naggar, A.K.9
Tallini, G.10
Vasko, V.11
Xing, M.12
-
16
-
-
0027955122
-
Molecular characterization of RET/PTC3; A novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma
-
M. Santoro, N. A. Dathan, M. T. Berlingieri et al., "Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma", Oncogene, vol. 9, no. 2, pp. 509-516, 1994. (Pubitemid 24041530)
-
(1994)
Oncogene
, vol.9
, Issue.2
, pp. 509-516
-
-
Santoro, M.1
Dathan, N.A.2
Berlingieri, M.T.3
Bongarzone, I.4
Paulin, C.5
Grieco, M.6
Pierotti, M.A.7
Vecchio, G.8
Fusco, A.9
-
17
-
-
0030941779
-
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children
-
Y. E. Nikiforov, J. M. Rowland, K. E. Bove, H. Monforte-Munoz, and J. A. Fagin, "Distinct pattern of ret oncogene rearrangements in morphological variants of radiationinduced and sporadic thyroid papillary carcinomas in children", Cancer Research, vol. 57, no. 9, pp. 1690-1694, 1997. (Pubitemid 27199660)
-
(1997)
Cancer Research
, vol.57
, Issue.9
, pp. 1690-1694
-
-
Nikiforov, Y.E.1
Rowland, J.M.2
Bove, K.E.3
Monforte-Munoz, H.4
Fagin, J.A.5
-
18
-
-
0031933680
-
RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes
-
G. Tallini, M. Santoro, M. Helie et al., "RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes", Clinical Cancer Research, vol. 4, no. 2, pp. 287-294, 1998. (Pubitemid 28122740)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.2
, pp. 287-294
-
-
Tallini, G.1
Santoro, M.2
Helie, M.3
Carlomagno, F.4
Salvatore, G.5
Chiappetta, G.6
Carcangiu, M.L.7
Fusco, A.8
-
19
-
-
0035881322
-
Overexpression and overactivation of Akt in thyroid carcinoma
-
M. D. Ringel, N. Hayre, J. Saito et al., "Overexpression and overactivation of Akt in thyroid carcinoma", Cancer Research, vol. 61, no. 16, pp. 6105-6111, 2001. (Pubitemid 32762546)
-
(2001)
Cancer Research
, vol.61
, Issue.16
, pp. 6105-6111
-
-
Ringel, M.D.1
Hayre, N.2
Saito, J.3
Saunier, B.4
Schuppert, F.5
Burch, H.6
Bernet, V.7
Burman, K.D.8
Kohn, L.D.9
Saji, M.10
-
20
-
-
13044305289
-
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
-
DOI 10.1073/pnas.96.11.6199
-
H. Sun, R. Lesche, D. M. Li et al., "PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3, 4, 5, -trisphosphate and Akt/protein kinase B signaling pathway", Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 11, pp. 6199-6204, 1999. (Pubitemid 29256643)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.11
, pp. 6199-6204
-
-
Sun, H.1
Lesche, R.2
Li, D.-M.3
Liliental, J.4
Zhang, H.5
Gao, J.6
Gavrilova, N.7
Mueller, B.8
Liu, X.9
Wu, H.10
-
21
-
-
33847072340
-
Minireview: RET/PTC rearrangements and braf mutations in thyroid tumorigenesis
-
R. Ciampi and Y. E. Nikiforov, "Minireview: RET/PTC rearrangements and braf mutations in thyroid tumorigenesis", Endocrinology, vol. 148, no. 3, pp. 936-941, 2007.
-
(2007)
Endocrinology
, vol.148
, Issue.3
, pp. 936-941
-
-
Ciampi, R.1
Nikiforov, Y.E.2
-
22
-
-
0038664387
-
BRAF mutation in papillary thyroid carcinoma
-
Y. Cohen, M. Xing, E. Mambo et al., "BRAF mutation in papillary thyroid carcinoma", Journal of the National Cancer Institute, vol. 95, no. 8, pp. 625-627, 2003. (Pubitemid 36553510)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.8
, pp. 625-627
-
-
Cohen, Y.1
Xing, M.2
Mambo, E.3
Gou, Z.4
Wu, G.5
Trink, B.6
Beller, U.7
Westra, W.H.8
Ladenson, P.W.9
Sidransky, D.10
-
23
-
-
2442568538
-
V599E mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas
-
DOI 10.1210/jc.2003-031425
-
E. Puxeddu, S. Moretti, R. Elisei et al., "BRAFV599E mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas", Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 5, pp. 2414-2420, 2004. (Pubitemid 38619884)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.5
, pp. 2414-2420
-
-
Puxeddu, E.1
Moretti, S.2
Elisei, R.3
Romei, C.4
Pascucci, R.5
Martinelli, M.6
Marino, C.7
Avenia, N.8
Rossi, E.D.9
Fadda, G.10
Cavaliere, A.11
Ribacchi, R.12
Falorni, A.13
Pontecorvi, A.14
Pacini, F.15
Pinchera, A.16
Santeusanio, F.17
-
24
-
-
53749086690
-
BRAFV600E mutation and outcome of patients with papillary thyroid carcinoma: A 15-year median follow-up study
-
R. Elisei, C. Ugolini, D. Viola et al., "BRAFV600E mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study", Journal of Clinical Endocrinology and Metabolism, vol. 93, no. 10, pp. 3943-3949, 2008.
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.10
, pp. 3943-3949
-
-
Elisei, R.1
Ugolini, C.2
Viola, D.3
-
25
-
-
40749104889
-
BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma
-
DOI 10.1111/j.1365-2265.2007.03077.x
-
A. M. Costa, A. Herrero, M. F. Fresno et al., "BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma", Clinical Endocrinology, vol. 68, no. 4, pp. 618-634, 2008. (Pubitemid 351388702)
-
(2008)
Clinical Endocrinology
, vol.68
, Issue.4
, pp. 618-634
-
-
Costa, A.M.1
Herrero, A.2
Fresno, M.F.3
Heymann, J.4
Alvarez, J.A.5
Cameselle-Teijeiro, J.6
Garcia-Rostan, G.7
-
26
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
DOI 10.1038/nature00766
-
H. Davies, G. R. Bignell, C. Cox et al., "Mutations of the BRAF gene in human cancer", Nature, vol. 417, no. 6892, pp. 949-954, 2002. (Pubitemid 34716871)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmleri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.C.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
27
-
-
0347363834
-
Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf
-
DOI 10.1038/sj.onc.1207185
-
T. Brummer, H. Naegele, M. Reth, and Y. Misawa, "Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf", Oncogene, vol. 22, no. 55, pp. 8823-8834, 2003. (Pubitemid 38021498)
-
(2003)
Oncogene
, vol.22
, Issue.55
, pp. 8823-8834
-
-
Brummer, T.1
Naegele, H.2
Reth, M.3
Misawa, Y.4
-
28
-
-
85047691154
-
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
-
DOI 10.1172/JCI200523237
-
R. Ciampi, J. A. Knauf, R. Kerler et al., "Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer", Journal of Clinical Investigation, vol. 115, no. 1, pp. 94-101, 2005. (Pubitemid 40385509)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.1
, pp. 94-101
-
-
Ciampi, R.1
Knauf, J.A.2
Kerler, R.3
Gandhi, M.4
Zhu, Z.5
Nikiforova, M.N.6
Rabes, H.M.7
Fagin, J.A.8
Nikiforov, Y.E.9
-
29
-
-
2442642971
-
Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas
-
DOI 10.1016/j.canlet.2003.12.004, PII S0304383503008334
-
M. N. Nikiforova, R. Ciampi, G. Salvatore et al., "Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas", Cancer Letters, vol. 209, no. 1, pp. 1-6, 2004. (Pubitemid 38656111)
-
(2004)
Cancer Letters
, vol.209
, Issue.1
, pp. 1-6
-
-
Nikiforova, M.N.1
Ciampi, R.2
Salvatore, G.3
Santoro, M.4
Gandhi, M.5
Knauf, J.A.6
Thomas, G.A.7
Jeremiah, S.8
Bogdanova, T.I.9
Tronko, M.D.10
Fagin, J.A.11
Nikiforov, Y.E.12
-
30
-
-
33644773510
-
Low frequency of BRAF mutations in adult patients with papillary thyroid cancers following childhood radiation exposure
-
DOI 10.1089/thy.2006.16.61
-
B. J. Collins, A. B. Schneider, R. A. Prinz, and X. Xu, "Low frequency of BRAF mutations in adult patients with papillary thyroid cancers following childhood radiation exposure", Thyroid, vol. 16, no. 1, pp. 61-66, 2006. (Pubitemid 43346505)
-
(2006)
Thyroid
, vol.16
, Issue.1
, pp. 61-66
-
-
Collins, B.J.1
Schneider, A.B.2
Prinz, R.A.3
Xu, X.4
-
31
-
-
28744442816
-
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
-
DOI 10.1210/jc.2005-0987
-
M. Xing, W. H. Westra, R. P. Tufano et al., "BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 12, pp. 6373-6379, 2005. (Pubitemid 41759286)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.12
, pp. 6373-6379
-
-
Xing, M.1
Westra, W.H.2
Tufano, R.P.3
Cohen, Y.4
Rosenbaum, E.5
Rhoden, K.J.6
Carson, K.A.7
Vasko, V.8
Larin, A.9
Tallini, G.10
Tolaney, S.11
Holt, E.H.12
Hui, P.13
Umbricht, C.B.14
Basaria, S.15
Ewertz, M.16
Tufaro, A.P.17
Califano, J.A.18
Ringel, M.D.19
Zeiger, M.A.20
Sidransky, D.21
Ladenson, P.W.22
more..
-
32
-
-
10744222003
-
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas
-
DOI 10.1210/jc.2003-030838
-
M. N. Nikiforova, E. T. Kimura, M. Gandhi et al., "BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas", Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 11, pp. 5399-5404, 2003. (Pubitemid 37452745)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.11
, pp. 5399-5404
-
-
Nikiforova, M.N.1
Kimura, E.T.2
Gandhi, M.3
Biddinger, P.W.4
Knauf, J.A.5
Basolo, F.6
Zhu, Z.7
Giannini, R.8
Salvatore, G.9
Fusco, A.10
Santoro, M.11
Fagin, J.A.12
Nikiforov, Y.E.13
-
33
-
-
33645232222
-
Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas
-
DOI 10.1097/01.pas.0000176432.73455.1b, PII 0000047820060200000010
-
A. J. Adeniran, Z. Zhu, M. Gandhi et al., "Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas", American Journal of Surgical Pathology, vol. 30, no. 2, pp. 216-222, 2006. (Pubitemid 43740191)
-
(2006)
American Journal of Surgical Pathology
, vol.30
, Issue.2
, pp. 216-222
-
-
Adeniran, A.J.1
Zhu, Z.2
Gandhi, M.3
Steward, D.L.4
Fidler, J.P.5
Giordano, T.J.6
Biddinger, P.W.7
Nikiforov, Y.E.8
-
34
-
-
16644384144
-
The BRAFT1796A transversion is a prevalent mutational event in human thyroid microcarcinoma
-
I. Sedliarou, V. Saenko, D. Lantsov et al., "The BRAFT1796A transversion is a prevalent mutational event in human thyroid microcarcinoma", International journal of oncology, vol. 25, no. 6, pp. 1729-1735, 2004.
-
(2004)
International Journal of Oncology
, vol.25
, Issue.6
, pp. 1729-1735
-
-
Sedliarou, I.1
Saenko, V.2
Lantsov, D.3
-
35
-
-
59449090715
-
Analysis of differential BRAFV600E mutational status in high aggressive papillary thyroid microcarcinoma
-
X. Lee, M. Gao, Y. Ji et al., "Analysis of differential BRAFV600E mutational status in high aggressive papillary thyroid microcarcinoma", Annals of Surgical Oncology, vol. 16, no. 2, pp. 240-245, 2009.
-
(2009)
Annals of Surgical Oncology
, vol.16
, Issue.2
, pp. 240-245
-
-
Lee, X.1
Gao, M.2
Ji, Y.3
-
36
-
-
6044219917
-
Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer
-
DOI 10.1038/sj.onc.1207980
-
M. Frattini, C. Ferrario, P. Bressan et al., "Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer", Oncogene, vol. 23, no. 44, pp. 7436-7440, 2004. (Pubitemid 39382146)
-
(2004)
Oncogene
, vol.23
, Issue.44
, pp. 7436-7440
-
-
Frattini, M.1
Ferrario, C.2
Bressan, P.3
Balestra, D.4
De Cecco, L.5
Mondellini, P.6
Bongarzone, I.7
Collini, P.8
Gariboldi, M.9
Pilotti, S.10
Pierotti, M.A.11
Greco, A.12
-
37
-
-
0043170833
-
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC
-
DOI 10.1038/sj.onc.1206706
-
P. Soares, V. Trovisco, A. S. Rocha et al., "BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC", Oncogene, vol. 22, no. 29, pp. 4578-4580, 2003. (Pubitemid 36920701)
-
(2003)
Oncogene
, vol.22
, Issue.29
, pp. 4578-4580
-
-
Soares, P.1
Trovisco, V.2
Rocha, A.S.3
Lima, J.4
Castro, P.5
Preto, A.6
Maximo, V.7
Botelho, T.8
Seruca, R.9
Sobrinho-Simoes, M.10
-
38
-
-
18844437226
-
Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations
-
DOI 10.1002/cncr.21073
-
R. M. Quiros, H. G. Ding, P. Gattuso, R. A. Prinz, and X. Xu, "Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations", Cancer, vol. 103, no. 11, pp. 2261-2268, 2005. (Pubitemid 40686569)
-
(2005)
Cancer
, vol.103
, Issue.11
, pp. 2261-2268
-
-
Quiros, R.M.1
Ding, H.G.2
Gattuso, P.3
Prinz, R.A.4
Xu, X.5
-
39
-
-
34447134910
-
Brief report: BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism
-
DOI 10.1210/jc.2006-2707
-
C. Durante, E. Puxeddu, E. Ferretti et al., "Brief report: BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism", Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 7, pp. 2840-2843, 2007. (Pubitemid 47037399)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.7
, pp. 2840-2843
-
-
Durante, C.1
Puxeddu, E.2
Ferretti, E.3
Morisi, R.4
Moretti, S.5
Bruno, R.6
Barbi, F.7
Avenia, N.8
Scipioni, A.9
Verrienti, A.10
Tosi, E.11
Cavaliere, A.12
Gulino, A.13
Filetti, S.14
Russo, D.15
-
40
-
-
33947290100
-
Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant
-
DOI 10.1158/1078-0432.CCR-06-1753
-
D. Liu, S. Hu, P. Hou, D. Jiang, S. Condouris, and M. Xing, "Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant", Clinical Cancer Research, vol. 13, no. 4, pp. 1341-1349, 2007. (Pubitemid 46424076)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1341-1349
-
-
Liu, D.1
Hu, S.2
Hou, P.3
Jiang, D.4
Condouris, S.5
Xing, M.6
-
41
-
-
70350554104
-
The BRAFV600E oncogene induces transforming growth factor β secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer
-
G. Riesco-Eizaguirre, I. Rodríguez, A. De La Vieja et al., "The BRAFV600E oncogene induces transforming growth factor β secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer", Cancer Research, vol. 69, no. 21, pp. 8317-8325, 2009.
-
(2009)
Cancer Research
, vol.69
, Issue.21
, pp. 8317-8325
-
-
Riesco-Eizaguirre, G.1
Rodríguez, I.2
De La Vieja, A.3
-
42
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
J. A. Fagin, K. Matsuo, A. Karmakar, Dan Lin Chen, S. H. Tang, and H. P. Koeffler, "High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas", Journal of Clinical Investigation, vol. 91, no. 1, pp. 179-184, 1993. (Pubitemid 23037270)
-
(1993)
Journal of Clinical Investigation
, vol.91
, Issue.1
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Dan Lin Chen4
Tang, S.-H.5
Koeffler, H.P.6
-
43
-
-
0035354187
-
Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation
-
L. Ludwig, H. Kessler, M. Wagner et al., "Nuclear factor-?B is constitutively active in C-cell carcinoma and required for RET-induced transformation", Cancer Research, vol. 61, no. 11, pp. 4526-4535, 2001. (Pubitemid 32685784)
-
(2001)
Cancer Research
, vol.61
, Issue.11
, pp. 4526-4535
-
-
Ludwig, L.1
Kessler, H.2
Wagner, M.3
Hoang-Vu, C.4
Dralle, H.5
Adler, G.6
Bohm, B.O.7
Schmid, R.M.8
-
44
-
-
0030929178
-
High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation
-
A. Bounacer, R. Wicker, B. Caillou et al., "High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation", Oncogene, vol. 15, no. 11, pp. 1263-1273, 1997. (Pubitemid 27429741)
-
(1997)
Oncogene
, vol.15
, Issue.11
, pp. 1263-1273
-
-
Bounacer, A.1
Wicker, R.2
Caillou, B.3
Cailleux, A.F.4
Sarasin, A.5
Schlumberger, M.6
Suarez, H.G.7
-
45
-
-
0034453001
-
The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults
-
DOI 10.1210/jc.85.3.1170
-
C. L. Fenton, Y. Lukes, D. Nicholson, C. A. Dinauer, G. L. Francis, and R. M. Tuttle, "The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults", Journal of Clinical Endocrinology and Metabolism, vol. 85, no. 3, pp. 1170-1175, 2000. (Pubitemid 32269367)
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, Issue.3
, pp. 1170-1175
-
-
Fenton, C.L.1
Lukes, Y.2
Nicholson, D.3
Dinauer, C.A.4
Francis, G.L.5
Tuttle, R.M.6
-
46
-
-
0034688338
-
Preferential induction of RET/PTC1 rearrangement by X-ray irradiation
-
T. Mizuno, K. S. Iwamoto, S. Kyoizumi et al., "Preferential induction of RET/PTC1 rearrangement by X-ray irradiation", Oncogene, vol. 19, no. 3, pp. 438-443, 2000. (Pubitemid 30077345)
-
(2000)
Oncogene
, vol.19
, Issue.3
, pp. 438-443
-
-
Mizuno, T.1
Iwamoto, K.S.2
Kyoizumi, S.3
Nagamura, H.4
Shinohara, T.5
Koyama, K.6
Seyama, T.7
Hamatani, K.8
-
47
-
-
0031031158
-
Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis
-
DOI 10.1097/00005537-199701000-00019
-
A. Wirtschafter, R. Schmidt, D. Rosen et al., "Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis", Laryngoscope, vol. 107, no. 1, pp. 95-100, 1997. (Pubitemid 27045201)
-
(1997)
Laryngoscope
, vol.107
, Issue.1
, pp. 95-100
-
-
Wirtschafter, A.1
Schmidt, R.2
Rosen, D.3
Kundu, N.4
Santoro, M.5
Fusco, A.6
Multhaupt, H.7
Atkins, J.P.8
Rosen, M.R.9
Keane, W.M.10
Rothstein, J.L.11
-
48
-
-
0033796849
-
Ret/PTC-1 activation in Hashimoto thyroiditis
-
O. M. Sheils, J. J. O'Leary, V. Uhlmann, K. Lüttich, and E. C. Sweeney, "ret/PTC-1 activation in Hashimoto thyroiditis", International Journal of Surgical Pathology, vol. 8, no. 3, pp. 185-189, 2000.
-
(2000)
International Journal of Surgical Pathology
, vol.8
, Issue.3
, pp. 185-189
-
-
Sheils, O.M.1
O'Leary, J.J.2
Uhlmann, V.3
Lüttich, K.4
Sweeney, E.C.5
-
49
-
-
0036127871
-
Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas
-
M. N. Nikiforova, C. M. Caudill, P. Biddinger, and Y. E. Nikiforov, "Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas", International Journal of Surgical Pathology, vol. 10, no. 1, pp. 15-22, 2002. (Pubitemid 34245954)
-
(2002)
International Journal of Surgical Pathology
, vol.10
, Issue.1
, pp. 15-22
-
-
Nikiforova, M.N.1
Caudill, C.M.2
Biddinger, P.3
Nikiforov, Y.E.4
-
50
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
DOI 10.1038/nature04483, PII NATURE04483
-
N. Ferrara and R. S. Kerbel, "Angiogenesis as a therapeutic target", Nature, vol. 438, no. 7070, pp. 967-974, 2005. (Pubitemid 43093963)
-
(2005)
Nature
, vol.438
, Issue.7070
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
51
-
-
0035090293
-
Increased expression of the vascular endothelial growth factor is a pejorative prognosis marker in papillary thyroid carcinoma
-
DOI 10.1210/jc.86.2.656
-
M. Klein, J. M. Vignaud, V. Hennequin et al., "Increased expression of the vascular endothelial growth factor is a pejorative prognosis marker in papillary thyroid carcinoma", Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 2, pp. 656-658, 2001. (Pubitemid 32207476)
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, Issue.2
, pp. 656-658
-
-
Klein, M.1
Vignaud, J.-M.2
Hennequin, V.3
Toussaint, B.4
Bresler, L.5
Plenat, F.6
Leclere, J.7
Duprez, A.8
Weryha, G.9
-
52
-
-
0035034282
-
Intensity of vascular endothelial growth factor expression is associated with increased risk of recurrence and decreased disease-free survival in papillary thyroid cancer
-
DOI 10.1067/msy.2001.112592
-
C. M. Lennard, A. Patel, J. Wilson et al., "Intensity of vascular endothelial growth factor expression is associated with increased risk of recurrence and decreased disease-free survival in papillary thyroid cancer", Surgery, vol. 129, no. 5, pp. 552-558, 2001. (Pubitemid 32374986)
-
(2001)
Surgery
, vol.129
, Issue.5
, pp. 552-558
-
-
Lennard, C.M.1
Patel, A.2
Wilson, J.3
Reinhardt, B.4
Tuman, C.5
Fenton, C.6
Blair, E.7
Francis, G.L.8
Tuttle, R.M.9
-
53
-
-
0032775391
-
PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation
-
DOI 10.1016/S0378-1119(99)00206-1, PII S0378111999002061
-
A. K. Ghosh, I. Grigorieva, R. Steele, R. G. Hoover, and R. B. Ray, "PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation", Gene, vol. 235, no. 1-2, pp. 85-91, 1999. (Pubitemid 29327286)
-
(1999)
Gene
, vol.235
, Issue.1-2
, pp. 85-91
-
-
Ghosh, A.K.1
Grigorieva, I.2
Steele, R.3
Hoover, R.G.4
Ray, R.B.5
-
54
-
-
0033575287
-
PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway
-
M. Tamura, J. Gu, E. H. J. Danen, T. Takino, S. Miyamoto, and K. M. Yamada, "PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway", Journal of Biological Chemistry, vol. 274, no. 29, pp. 20693-20703, 1999.
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.29
, pp. 20693-20703
-
-
Tamura, M.1
Gu, J.2
Danen, E.H.J.3
Takino, T.4
Miyamoto, S.5
Yamada, K.M.6
-
55
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
DOI 10.1038/ng0497-356
-
P. A. Steck, M. A. Pershouse, S. A. Jasser et al., "Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers", Nature Genetics, vol. 15, no. 4, pp. 356-362, 1997. (Pubitemid 27147102)
-
(1997)
Nature Genetics
, vol.15
, Issue.4
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.F.14
Tavtigian, S.V.15
-
56
-
-
0037431435
-
Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma
-
DOI 10.1002/ijc.10962
-
D. S. Byun, K. Cho, B. K. Ryu et al., "Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma", International Journal of Cancer, vol. 104, no. 3, pp. 318-327, 2003. (Pubitemid 36249814)
-
(2003)
International Journal of Cancer
, vol.104
, Issue.3
, pp. 318-327
-
-
Byun, D.-S.1
Cho, K.2
Ryu, B.-K.3
Lee, M.-G.4
Park, J.-I.5
Chae, K.-S.6
Kim, H.-J.7
Chi, S.-G.8
-
57
-
-
0038067837
-
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
-
DOI 10.1242/dev.00392
-
T. Kimura, A. Suzuki, Y. Fujita et al., "Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production", Development, vol. 130, no. 8, pp. 1691-1700, 2003. (Pubitemid 36527527)
-
(2003)
Development
, vol.130
, Issue.8
, pp. 1691-1700
-
-
Kimura, T.1
Suzuki, A.2
Fujita, Y.3
Yomogida, K.4
Lomeli, H.5
Asada, N.6
Ikeuchi, M.7
Nagy, A.8
Mak, T.W.9
Nakano, T.10
-
58
-
-
31944448885
-
Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation
-
DOI 10.1073/pnas.0510652103
-
S. Wang, A. J. Garcia, M. Wu, D. A. Lawson, O. N. Witte, and H. Wu, "Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation", Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 5, pp. 1480-1485, 2006. (Pubitemid 43191191)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.5
, pp. 1480-1485
-
-
Wang, S.1
Garcia, A.J.2
Wu, M.3
Lawson, D.A.4
Witte, O.N.5
Wu, H.6
-
59
-
-
0031804873
-
Mutation analysis of the putative tumor suppressor PTEN/MMAC1 in human ovarian cancer
-
A. Yokomizo, D. J. Tindall, L. Hartmann, R. B. Jenkins, D. I. Smith, and W. Liu, "Mutation analysis of the putative tumor suppressor PTEN/MMAC1 in human ovarian cancer", International Journal of Oncology, vol. 13, no. 1, pp. 101-105, 1998. (Pubitemid 28267502)
-
(1998)
International Journal of Oncology
, vol.13
, Issue.1
, pp. 101-105
-
-
Yokomizo, A.1
Tindall, D.J.2
Hartmann, L.3
Jenkins, R.B.4
Smith, D.I.5
Liu, W.6
-
60
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
M. E. McMenamin, P. Soung, S. Perera, I. Kaplan, M. Loda, and W. R. Sellers, "Loss of PTEN expression in paraffinembedded primary prostate cancer correlates with high Gleason score and advanced stage", Cancer Research, vol. 59, no. 17, pp. 4291-4296, 1999. (Pubitemid 29418745)
-
(1999)
Cancer Research
, vol.59
, Issue.17
, pp. 4291-4296
-
-
McMenamin, M.E.1
Soung, P.2
Perera, S.3
Kaplan, I.4
Loda, M.5
Sellers, W.R.6
-
61
-
-
55549084534
-
Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors
-
P. Hou, M. Ji, and M. Xing, "Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors", Cancer, vol. 113, no. 9, pp. 2440-2447, 2008.
-
(2008)
Cancer
, vol.113
, Issue.9
, pp. 2440-2447
-
-
Hou, P.1
Ji, M.2
Xing, M.3
-
62
-
-
33947284529
-
Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer
-
DOI 10.1158/1078-0432.CCR-06-1125
-
P. Hou, D. Liu, Y. Shan et al., "Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer", Clinical Cancer Research, vol. 13, no. 4, pp. 1161-1170, 2007. (Pubitemid 46424056)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1161-1170
-
-
Hou, P.1
Liu, D.2
Shan, Y.3
Hu, S.4
Studeman, K.5
Condouris, S.6
Wang, Y.7
Trink, A.8
El-Naggar, A.K.9
Tallini, G.10
Vasko, V.11
Xing, M.12
-
63
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-1443
-
S. M. Wilhelm, C. Carter, L. Tang et al., "BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis", Cancer Research, vol. 64, no. 19, pp. 7099-7109, 2004. (Pubitemid 39331023)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
64
-
-
51049092292
-
Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement
-
Y. C. Henderson, S. H. Ann, Y. Kang, and G. L. Clayman, "Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement", Clinical Cancer Research, vol. 14, no. 15, pp. 4908-4914, 2008.
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.15
, pp. 4908-4914
-
-
Henderson, Y.C.1
Ann, S.H.2
Kang, Y.3
Clayman, G.L.4
-
65
-
-
34247857540
-
Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: A review of four phase I trials in patients with advanced refractory solid tumors
-
DOI 10.1634/theoncologist.12-4-426
-
D. Strumberg, J. W. Clark, A. Awada et al., "Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors", Oncologist, vol. 12, no. 4, pp. 426-437, 2007. (Pubitemid 46698720)
-
(2007)
Oncologist
, vol.12
, Issue.4
, pp. 426-437
-
-
Strumberg, D.1
Clark, J.W.2
Awada, A.3
Moore, M.J.4
Richly, H.5
Hendlisz, A.6
Hirte, H.W.7
Eder, J.P.8
Lenz, H.-J.9
Schwartzh, B.10
-
66
-
-
50649095250
-
Phase II trial of sorafenib in advanced thyroid cancer
-
V. Gupta-Abramson, A. B. Troxel, A. Nellore et al., "Phase II trial of sorafenib in advanced thyroid cancer", Journal of Clinical Oncology, vol. 26, no. 29, pp. 4714-4719, 2008.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.29
, pp. 4714-4719
-
-
Gupta-Abramson, V.1
Troxel, A.B.2
Nellore, A.3
-
67
-
-
63849265332
-
Phase II trial of sorafenib in metastatic thyroid cancer
-
R. T. Kloos, M. D. Ringel, M. V. Knopp et al., "Phase II trial of sorafenib in metastatic thyroid cancer", Journal of Clinical Oncology, vol. 27, no. 10, pp. 1675-1684, 2009.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.10
, pp. 1675-1684
-
-
Kloos, R.T.1
Ringel, M.D.2
Knopp, M.V.3
-
68
-
-
72949106263
-
Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma
-
H. Hoftijzer, K. A. Heemstra, H. Morreau et al., "Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma", European Journal of Endocrinology, vol. 161, no. 6, pp. 923-931, 2009.
-
(2009)
European Journal of Endocrinology
, vol.161
, Issue.6
, pp. 923-931
-
-
Hoftijzer, H.1
Heemstra, K.A.2
Morreau, H.3
-
69
-
-
77954476036
-
Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: The M. D. Anderson experience
-
M. E. Cabanillas, S. G. Waguespack, Y. Bronstein et al., "Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 6, pp. 2588-2595, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.6
, pp. 2588-2595
-
-
Cabanillas, M.E.1
Waguespack, S.G.2
Bronstein, Y.3
-
70
-
-
77952468875
-
Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer
-
E. T. Lam, M. D. Ringel, R. T. Kloos et al., "Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer", Journal of Clinical Oncology, vol. 28, no. 14, pp. 2323-2330, 2010.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.14
, pp. 2323-2330
-
-
Lam, E.T.1
Ringel, M.D.2
Kloos, R.T.3
-
71
-
-
55949123335
-
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
-
M. Schmidinger, C. C. Zielinski, U. M. Vogl et al., "Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma", Journal of Clinical Oncology, vol. 26, no. 32, pp. 5204-5212, 2008.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.32
, pp. 5204-5212
-
-
Schmidinger, M.1
Zielinski, C.C.2
Vogl, U.M.3
-
72
-
-
70450224682
-
Sorafenib-induced acute myocardial infarction due to coronary artery spasm
-
Y. Arima, S. Oshima, K. Noda et al., "Sorafenib-induced acute myocardial infarction due to coronary artery spasm", Journal of Cardiology, vol. 54, no. 3, pp. 512-515, 2009.
-
(2009)
Journal of Cardiology
, vol.54
, Issue.3
, pp. 512-515
-
-
Arima, Y.1
Oshima, S.2
Noda, K.3
-
73
-
-
68949094219
-
Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib
-
J. P. Arnault, J. Wechsler, B. Escudier et al., "Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib", Journal of Clinical Oncology, vol. 27, no. 23, pp. e59-e61, 2009.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.23
-
-
Arnault, J.P.1
Wechsler, J.2
Escudier, B.3
-
74
-
-
77956513286
-
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
-
G. Bollag, P. Hirth, J. Tsai et al., "Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma", Nature, vol. 467, no. 7315, pp. 596-599, 2010.
-
(2010)
Nature
, vol.467
, Issue.7315
, pp. 596-599
-
-
Bollag, G.1
Hirth, P.2
Tsai, J.3
-
75
-
-
77957089182
-
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
-
E. W. Joseph, C. A. Pratilas, P. I. Poulikakos et al., "The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner", Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 33, pp. 14903-14908, 2010.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.33
, pp. 14903-14908
-
-
Joseph, E.W.1
Pratilas, C.A.2
Poulikakos, P.I.3
-
76
-
-
75149188152
-
Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells
-
P. Salerno, V. De Falco, A. Tamburrino et al., "Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 1, pp. 450-455, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.1
, pp. 450-455
-
-
Salerno, P.1
De Falco, V.2
Tamburrino, A.3
-
77
-
-
47249097988
-
BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells
-
E. Sala, L. Mologni, S. Truffa, C. Gaetano, G. E. Bollag, and C. Gambacorti-Passerini, "BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells", Molecular Cancer Research, vol. 6, no. 5, pp. 751-759, 2008.
-
(2008)
Molecular Cancer Research
, vol.6
, Issue.5
, pp. 751-759
-
-
Sala, E.1
Mologni, L.2
Truffa, S.3
Gaetano, C.4
Bollag, G.E.5
Gambacorti-Passerini, C.6
-
78
-
-
77950954465
-
Differential sensitivity of melanoma cell lines with BRAFV600Emutation to the specific Raf inhibitor PLX4032
-
J. N. Søndergaard, R. Nazarian, Q. Wang et al., "Differential sensitivity of melanoma cell lines with BRAFV600Emutation to the specific Raf inhibitor PLX4032", Journal of Translational Medicine, vol. 8, article 39, 2010.
-
(2010)
Journal of Translational Medicine
, vol.8
, pp. 39
-
-
Søndergaard, J.N.1
Nazarian, R.2
Wang, Q.3
-
79
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
K. T. Flaherty, I. Puzanov, K. B. Kim et al., "Inhibition of mutated, activated BRAF in metastatic melanoma", New England Journal of Medicine, vol. 363, no. 9, pp. 809-819, 2010.
-
(2010)
New England Journal of Medicine
, vol.363
, Issue.9
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
80
-
-
68949106943
-
A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients with advanced solid tumors
-
G. K. Schwartz, S. Robertson, A. Shen et al., "A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients with advanced solid tumors", Journal of Clinical Oncology, vol. 27, no. 15s, abstract 3513, 2009.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.15 S
, pp. 3513
-
-
Schwartz, G.K.1
Robertson, S.2
Shen, A.3
-
81
-
-
33749544080
-
An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases
-
DOI 10.1210/jc.2005-2845
-
D. W. Kim, Y. S. Jo, H. S. Jung et al., "An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases", Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 10, pp. 4070-4076, 2006. (Pubitemid 44536887)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.10
, pp. 4070-4076
-
-
Dong, W.K.1
Young, S.J.2
Hye, S.J.3
Hyo, K.C.4
Jung, H.S.5
Ki, C.P.6
Su, H.P.7
Jung, H.H.8
So, Y.R.9
Gi, R.K.10
Lee, S.-J.11
Jo, K.-W.12
Shong, M.13
-
82
-
-
65749087602
-
Phase II study of sunitinib in refractory thyroid cancer
-
E. E. W. Cohen, B. M. Needles, K. J. Cullen et al., "Phase II study of sunitinib in refractory thyroid cancer", Journal of Clinical Oncology, vol. 26, abstract 6025, 2008.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 6025
-
-
Cohen, E.E.W.1
Needles, B.M.2
Cullen, K.J.3
-
83
-
-
75449104629
-
A case of advanced medullary thyroid carcinoma successfully treated with sunitinib
-
M. J. Bugalho, R. Domingues, and A. Borges, "A case of advanced medullary thyroid carcinoma successfully treated with sunitinib", Oncologist, vol. 14, no. 11, pp. 1083-1087, 2009.
-
(2009)
Oncologist
, vol.14
, Issue.11
, pp. 1083-1087
-
-
Bugalho, M.J.1
Domingues, R.2
Borges, A.3
-
84
-
-
34548764576
-
A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake
-
DOI 10.1210/jc.2007-0586
-
D. Mannavola, P. Coco, G. Vannucchi et al., "A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake", Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 9, pp. 3531-3534, 2007. (Pubitemid 47435331)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.9
, pp. 3531-3534
-
-
Mannavola, D.1
Coco, P.2
Vannucchi, G.3
Bertuelli, R.4
Carletto, M.5
Casali, P.G.6
Beck-Peccoz, P.7
Fugazzola, L.8
-
85
-
-
34248632840
-
Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity
-
DOI 10.1089/thy.2006.0308
-
E. Wong, L. S. Rosen, M. Mulay et al., "Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity", Thyroid, vol. 17, no. 4, pp. 351-355, 2007. (Pubitemid 46776140)
-
(2007)
Thyroid
, vol.17
, Issue.4
, pp. 351-355
-
-
Wong, E.1
Rosen, L.S.2
Mulay, M.3
VanVugt, A.4
Dinolfo, M.5
Tomoda, C.6
Sugawara, M.7
Hershman, J.M.8
-
86
-
-
77957366667
-
Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer
-
M. B. Bass, S. I. Sherman, M. J. Schlumberger et al., "Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 11, pp. 5018-5027, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.11
, pp. 5018-5027
-
-
Bass, M.B.1
Sherman, S.I.2
Schlumberger, M.J.3
-
87
-
-
85042521132
-
The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: A prospective single-center study
-
In press
-
V. Baldazzi, R. Tassi, A. Lapini, C. Santomaggio, M. Carini, and R. Mazzanti, "The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: a prospective single-center study", Urologic Oncology: Seminars and Original Investigations. In press.
-
Urologic Oncology: Seminars and Original Investigations
-
-
Baldazzi, V.1
Tassi, R.2
Lapini, A.3
Santomaggio, C.4
Carini, M.5
Mazzanti, R.6
-
88
-
-
78651361788
-
Hypothyroidism in patients with renal cell carcinoma: Blessing or curse?
-
M. Schmidinger, U. M. Vogl, M. Bojic et al., "Hypothyroidism in patients with renal cell carcinoma: blessing or curse?" Cancer, vol. 117, no. 3, pp. 534-544, 2011.
-
(2011)
Cancer
, vol.117
, Issue.3
, pp. 534-544
-
-
Schmidinger, M.1
Vogl, U.M.2
Bojic, M.3
-
89
-
-
36849023013
-
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
-
DOI 10.1016/S0140-6736(07)61865-0, PII S0140673607618650
-
T. F. Chu, M. A. Rupnick, R. Kerkela et al., "Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib", Lancet, vol. 370, no. 9604, pp. 2011-2019, 2007. (Pubitemid 350236338)
-
(2007)
Lancet
, vol.370
, Issue.9604
, pp. 2011-2019
-
-
Chu, T.F.1
Rupnick, M.A.2
Kerkela, R.3
Dallabrida, S.M.4
Zurakowski, D.5
Nguyen, L.6
Woulfe, K.7
Pravda, E.8
Cassiola, F.9
Desai, J.10
George, S.11
Morgan, J.A.12
Harris, D.M.13
Ismail, N.S.14
Chen, J.-H.15
Schoen, F.J.16
Van Den Abbeele, A.D.17
Demetri, G.D.18
Force, T.19
Chen, M.H.20
more..
-
90
-
-
77958194741
-
The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro
-
B. B. Hasinoff and D. Patel, "The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro", Toxicology and Applied Pharmacology, vol. 249, no. 2, pp. 132-139, 2010.
-
(2010)
Toxicology and Applied Pharmacology
, vol.249
, Issue.2
, pp. 132-139
-
-
Hasinoff, B.B.1
Patel, D.2
-
91
-
-
50949132320
-
Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics
-
M. H. Chen, R. Kerkelä, and T. Force, "Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics", Circulation, vol. 118, no. 1, pp. 84-95, 2008.
-
(2008)
Circulation
, vol.118
, Issue.1
, pp. 84-95
-
-
Chen, M.H.1
Kerkelä, R.2
Force, T.3
-
92
-
-
0037102369
-
ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
-
S. R. Wedge, D. J. Ogilvie, M. Dukes et al., "ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration", Cancer Research, vol. 62, no. 16, pp. 4645-4655, 2002.
-
(2002)
Cancer Research
, vol.62
, Issue.16
, pp. 4645-4655
-
-
Wedge, S.R.1
Ogilvie, D.J.2
Dukes, M.3
-
93
-
-
0037386774
-
Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase
-
F. Ciardiello, R. Caputo, V. Damiano et al., "Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase", Clinical Cancer Research, vol. 9, no. 4, pp. 1546-1556, 2003. (Pubitemid 36418413)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.4
, pp. 1546-1556
-
-
Ciardiello, F.1
Caputo, R.2
Damiano, V.3
Caputo, R.4
Troiani, T.5
Vitagliano, D.6
Carlomagno, F.7
Veneziani, B.M.8
Fontanini, G.9
Bianco, A.R.10
Tortora, G.11
-
94
-
-
33846850223
-
Vandetanib (ZD6474): An orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis
-
DOI 10.1517/13543784.16.2.239
-
R. S. Herbst, J. V. Heymach, M. S. O'Reilly, A. Onn, and A. J. Ryan, "Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis", Expert Opinion on Investigational Drugs, vol. 16, no. 2, pp. 239-249, 2007. (Pubitemid 46206638)
-
(2007)
Expert Opinion on Investigational Drugs
, vol.16
, Issue.2
, pp. 239-249
-
-
Herbst, R.S.1
Heymach, J.V.2
O'Reilly, M.S.3
Onn, A.4
Ryan, A.J.5
-
95
-
-
0037115405
-
ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases
-
F. Carlomagno, D. Vitagliano, T. Guida et al., "ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases", Cancer Research, vol. 62, no. 24, pp. 7284-7290, 2002. (Pubitemid 36025251)
-
(2002)
Cancer Research
, vol.62
, Issue.24
, pp. 7284-7290
-
-
Carlomagno, F.1
Vitagliano, D.2
Guida, T.3
Ciardiello, F.4
Tortora, G.5
Vecchio, G.6
Ryan, A.J.7
Fontanini, G.8
Fusco, A.9
Santoro, M.10
-
96
-
-
79251531655
-
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells
-
D. Vitagliano, V. De Falco, A. Tamburrino et al., "The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells", Endocrine-Related Cancer, vol. 18, no. 1, pp. 1-11, 2011.
-
(2011)
Endocrine-Related Cancer
, vol.18
, Issue.1
, pp. 1-11
-
-
Vitagliano, D.1
De Falco, V.2
Tamburrino, A.3
-
97
-
-
77649214078
-
Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer
-
S. A. Wells Jr., J. E. Gosnell, R. F. Gagel et al., "Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer", Journal of Clinical Oncology, vol. 28, no. 5, pp. 767-772, 2010.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.5
, pp. 767-772
-
-
Wells Jr., S.A.1
Gosnell, J.E.2
Gagel, R.F.3
-
99
-
-
77954478933
-
Vandetanib (100 mg) in patients with locally advanced or metastatic hereditary medullary thyroid cancer
-
B. G. Robinson, L. Paz-Ares, A. Krebs, J. Vasselli, and R. Haddad, "Vandetanib (100 mg) in patients with locally advanced or metastatic hereditary medullary thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 6, pp. 2664-2671, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.6
, pp. 2664-2671
-
-
Robinson, B.G.1
Paz-Ares, L.2
Krebs, A.3
Vasselli, J.4
Haddad, R.5
-
101
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
M. Carroll, S. Ohno-Jones, S. Tamura et al., "CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins", Blood, vol. 90, no. 12, pp. 4947-4952, 1997. (Pubitemid 28007210)
-
(1997)
Blood
, vol.90
, Issue.12
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmermann, J.5
Lydon, N.B.6
Gilliland, D.G.7
Druker, B.J.8
-
102
-
-
0037986203
-
The selective tyrosine kinase inhibitor, STI571, inhibits growth of anaplastic thyroid cancer cells
-
DOI 10.1210/jc.2002-021230
-
A. Podtcheko, A. Ohtsuru, S. Tsuda et al., "The selective tyrosine kinase inhibitor, STI571, inhibits growth of anaplastic thyroid cancer cells", Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 4, pp. 1889-1896, 2003. (Pubitemid 36623419)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.4
, pp. 1889-1896
-
-
Podtcheko, A.1
Ohtsuru, A.2
Tsuda, S.3
Namba, H.4
Saenko, V.5
Nakashima, M.6
Mitsutake, N.7
Kanda, S.8
Kurebayashi, J.9
Yamashita, S.10
-
103
-
-
2442423952
-
Imatinib Mesylate (Gleevec; STI571) Monotherapy Is Ineffective in Suppressing Human Anaplastic Thyroid Carcinoma Cell Growth in Vitro
-
DOI 10.1210/jc.2003-031734
-
J. M. Dziba and K. B. Ain, "Imatinib mesylate (Gleevec; STI571) monotherapy is ineffective in suppressing human anaplastic thyroid carcinoma cell growth in vitro", Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 5, pp. 2127-2135, 2004. (Pubitemid 38619841)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.5
, pp. 2127-2135
-
-
Dziba, J.M.1
Ain, K.B.2
-
104
-
-
34548749440
-
A phase II trial of imatinib therapy for metastatic medullary thyroid carcinoma
-
DOI 10.1210/jc.2007-0649
-
J. W. B. De Groot, B. A. Zonnenberg, P. Q. Van Ufford-Mannesse et al., "A phase II trial of imatinib therapy for metastatic medullary thyroid carcinoma", Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 9, pp. 3466-3469, 2007. (Pubitemid 47435321)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.9
, pp. 3466-3469
-
-
De Groot, J.W.B.1
Zonnenberg, B.A.2
Van Ufford-Mannesse, P.Q.3
De Vries, M.M.4
Links, T.P.5
Lips, C.J.M.6
Voest, E.E.7
-
105
-
-
34547801152
-
Efficacy of imatinib mesylate in advanced medullary thyroid carcinoma
-
DOI 10.1530/EJE-06-0695
-
K. Frank-Raue, M. Fabel, S. Delorme, U. Haberkorn, and F. Raue, "Efficacy of imatinib mesylate in advanced medullary thyroid carcinoma", European Journal of Endocrinology, vol. 157, no. 2, pp. 215-220, 2007. (Pubitemid 47233127)
-
(2007)
European Journal of Endocrinology
, vol.157
, Issue.2
, pp. 215-220
-
-
Frank-Raue, K.1
Fabel, M.2
Delorme, S.3
Haberkorn, U.4
Raue, F.5
-
106
-
-
78649958734
-
A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo
-
A. K. Samadi, R. Mukerji, A. Shah, B. N. Timmermann, and M. S. Cohen, "A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo", Surgery, vol. 148, no. 6, pp. 1228-1236, 2010.
-
(2010)
Surgery
, vol.148
, Issue.6
, pp. 1228-1236
-
-
Samadi, A.K.1
Mukerji, R.2
Shah, A.3
Timmermann, B.N.4
Cohen, M.S.5
-
107
-
-
34447322566
-
Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity
-
DOI 10.1158/1535-7163.MCT-07-0193
-
R. Kumar, V. B. Knick, S. K. Rudolph et al., "Pharmacokinetic- pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity", Molecular Cancer Therapeutics, vol. 6, no. 7, pp. 2012-2021, 2007. (Pubitemid 47052491)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.7
, pp. 2012-2021
-
-
Kumar, R.1
Knick, V.B.2
Rudolph, S.K.3
Johnson, J.H.4
Crosby, R.M.5
Crouthamel, M.-C.6
Hopper, T.M.7
Miller, C.G.8
Harrington, L.E.9
Onori, J.A.10
Mullin, R.J.11
Gilmer, T.M.12
Truesdale, A.T.13
Epperly, A.H.14
Boloor, A.15
Stafford, J.A.16
Luttrell, D.K.17
Cheung, M.18
-
108
-
-
78751501299
-
Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis
-
B. Gril, D. Palmieri, Y. Qian et al., "Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis", Clinical Cancer Research, vol. 17, no. 1, pp. 142-153, 2011.
-
(2011)
Clinical Cancer Research
, vol.17
, Issue.1
, pp. 142-153
-
-
Gril, B.1
Palmieri, D.2
Qian, Y.3
-
109
-
-
77956649079
-
A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer
-
M. Friedlander, K. C. Hancock, D. Rischin et al., "A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer", Gynecologic Oncology, vol. 119, no. 1, pp. 32-37, 2010.
-
(2010)
Gynecologic Oncology
, vol.119
, Issue.1
, pp. 32-37
-
-
Friedlander, M.1
Hancock, K.C.2
Rischin, D.3
-
110
-
-
77955503066
-
Phase II proof-of concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer
-
N. Altorki, M. E. Lane, T. Bauer et al., "Phase II proof-of concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer", Journal of Clinical Oncology, vol. 28, no. 19, pp. 3131-3137, 2010.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.19
, pp. 3131-3137
-
-
Altorki, N.1
Lane, M.E.2
Bauer, T.3
-
111
-
-
78650387508
-
Pazopanib in renal cell carcinoma
-
J. E. Ward and W. M. Stadler, "Pazopanib in renal cell carcinoma", Clinical Cancer Research, vol. 16, no. 24, pp. 5923-5927, 2010.
-
(2010)
Clinical Cancer Research
, vol.16
, Issue.24
, pp. 5923-5927
-
-
Ward, J.E.1
Stadler, W.M.2
-
112
-
-
77957359933
-
Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: Results of a phase 2 consortium study
-
K. C. Bible, V. J. Suman, J. R. Molina et al., "Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study", The Lancet Oncology, vol. 11, no. 10, pp. 962-972, 2010.
-
(2010)
The Lancet Oncology
, vol.11
, Issue.10
, pp. 962-972
-
-
Bible, K.C.1
Suman, V.J.2
Molina, J.R.3
-
113
-
-
33749000911
-
AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts
-
DOI 10.1158/0008-5472.CAN-05-4665
-
A. Polverino, A. Coxon, C. Starnes et al., "AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts", Cancer Research, vol. 66, no. 17, pp. 8715-8721, 2006. (Pubitemid 44449188)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8715-8721
-
-
Polverino, A.1
Coxon, A.2
Starnes, C.3
Diaz, Z.4
DeMelfi, T.5
Wang, L.6
Bready, J.7
Estrada, J.8
Cattley, R.9
Kaufman, S.10
Chen, D.11
Gan, Y.12
Kumar, G.13
Meyer, J.14
Neervannan, S.15
Alva, G.16
Talvenheimo, J.17
Montestruque, S.18
Tasker, A.19
Patel, V.20
Radinsky, R.21
Kendall, R.22
more..
-
114
-
-
34347235531
-
Safety, pharmacokinetics, and efficacy of AMG 706, an oral multikinase inhibitor, in patients with advanced solid tumors
-
DOI 10.1200/JCO.2006.07.8170
-
L. S. Rosen, R. Kurzrock, M. Mulay et al., "Safety, pharmacokinetics, and efficacy of AMG 706, an oral multikinase inhibitor, in patients with advanced solid tumors", Journal of Clinical Oncology, vol. 25, no. 17, pp. 2369-2376, 2007. (Pubitemid 46999207)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.17
, pp. 2369-2376
-
-
Rosen, L.S.1
Kurzrock, R.2
Mulay, M.3
Van Vugt, A.4
Purdom, M.5
Ng, C.6
Silverman, J.7
Koutsoukos, A.8
Sun, Y.-N.9
Bass, M.B.10
Xu, R.Y.11
Polverino, A.12
Wiezorek, J.S.13
Chang, D.D.14
Benjamin, R.15
Herbst, R.S.16
-
115
-
-
46449117698
-
Motesanib diphosphate in progressive differentiated thyroid cancer
-
DOI 10.1056/NEJMoa075853
-
S. I. Sherman, L. J. Wirth, J. P. Droz et al., "Motesanib diphosphate in progressive differentiated thyroid cancer", New England Journal of Medicine, vol. 359, no. 1, pp. 31-42, 2008. (Pubitemid 351931094)
-
(2008)
New England Journal of Medicine
, vol.359
, Issue.1
, pp. 31-42
-
-
Sherman, S.I.1
Wirth, L.J.2
Droz, J.-P.3
Hofmann, M.4
Bastholt, L.5
Martins, R.G.6
Licitra, L.7
Eschenberg, M.J.8
Sun, Y.-N.9
Juan, T.10
Stepan, D.E.11
Schlumberger, M.J.12
-
116
-
-
68949108390
-
Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer
-
M. J. Schlumberger, R. Elisei, L. Bastholt et al., "Phase II study of safety and efficacy of motesanib in patients with progressive or symptomatic, advanced or metastatic medullary thyroid cancer", Journal of Clinical Oncology, vol. 27, no. 23, pp. 3794-3801, 2009.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.23
, pp. 3794-3801
-
-
Schlumberger, M.J.1
Elisei, R.2
Bastholt, L.3
-
117
-
-
77957366667
-
Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer
-
M. B. Bass, S. I. Sherman, M. J. Schlumberger et al., "Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 11, pp. 5018-5027, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.11
, pp. 5018-5027
-
-
Bass, M.B.1
Sherman, S.I.2
Schlumberger, M.J.3
-
118
-
-
24944453855
-
Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: Pharmacokinetic and clinical results
-
H. S. Rugo, R. S. Herbst, G. Liu et al., "Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results", Journal of Clinical Oncology, vol. 23, no. 24, pp. 5474-5483, 2005.
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.24
, pp. 5474-5483
-
-
Rugo, H.S.1
Herbst, R.S.2
Liu, G.3
-
119
-
-
50649095801
-
Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: Results from a phase II study
-
E. E. W. Cohen, L. S. Rosen, E. E. Vokes et al., "Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study", Journal of Clinical Oncology, vol. 26, no. 29, pp. 4708-4713, 2008.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.29
, pp. 4708-4713
-
-
Cohen, E.E.W.1
Rosen, L.S.2
Vokes, E.E.3
-
120
-
-
4344644698
-
Activation of the Hepatocyte Growth Factor (HGF)-Met system in papillary thyroid cancer: Biological effects of HGF in thyroid cancer cells depend on Met expression levels
-
DOI 10.1210/en.2003-1762
-
R. Mineo, A. Costantino, F. Frasca et al., "Activation of the Hepatocyte Growth Factor (HGF)-Met system in papillary thyroid cancer: biological effects of HGF in thyroid cancer cells depend on Met expression levels", Endocrinology, vol. 145, no. 9, pp. 4355-4365, 2004. (Pubitemid 39120585)
-
(2004)
Endocrinology
, vol.145
, Issue.9
, pp. 4355-4365
-
-
Mineo, R.1
Costantino, A.2
Frasca, F.3
Sciacca, L.4
Russo, S.5
Vigneri, R.6
Belfiore, A.7
-
121
-
-
77952930543
-
A Phase I study of XL184, a MET, VEGFR2, and RET kinase inhibitor, administered orally to patients with advanced malignancies, including a subgroup of patients with medullary thyroid carcinoma
-
Geneva, Switzerland, October, poster number 379
-
R. Kurzrock, S. Sherman, D. Hong et al., "A Phase I study of XL184, a MET, VEGFR2, and RET kinase inhibitor, administered orally to patients with advanced malignancies, including a subgroup of patients with medullary thyroid carcinoma", in the EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics, Geneva, Switzerland, October 2008, poster number 379.
-
(2008)
The EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics
-
-
Kurzrock, R.1
Sherman, S.2
Hong, D.3
-
122
-
-
79951709994
-
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer
-
A. Antonelli, G. Bocci, C. La Motta et al., "Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 96, no. 2, pp. E288-E296, 2011.
-
(2011)
Journal of Clinical Endocrinology and Metabolism
, vol.96
, Issue.2
-
-
Antonelli, A.1
Bocci, G.2
La Motta, C.3
-
123
-
-
40949130884
-
A phase II study of gefitinib in patients with advanced thyroid cancer
-
DOI 10.1089/thy.2007.0120
-
N. A. Pennell, G. H. Daniels, R. I. Haddad et al., "A phase II study of gefitinib in patients with advanced thyroid cancer", Thyroid, vol. 18, no. 3, pp. 317-323, 2008. (Pubitemid 351415790)
-
(2008)
Thyroid
, vol.18
, Issue.3
, pp. 317-323
-
-
Pennell, N.A.1
Daniels, G.H.2
Haddad, R.I.3
Ross, D.S.4
Evans, T.5
Wirth, L.J.6
Fidias, P.H.7
Temel, J.S.8
Gurubhagavatula, S.9
Heist, R.S.10
Clark, J.R.11
Lynch, T.J.12
-
124
-
-
77954219743
-
Targeted therapy of thyroid cancer
-
S. I. Sherman, "Targeted therapy of thyroid cancer", Biochemical Pharmacology, vol. 80, no. 5, pp. 592-601, 2010.
-
(2010)
Biochemical Pharmacology
, vol.80
, Issue.5
, pp. 592-601
-
-
Sherman, S.I.1
-
125
-
-
77954503387
-
Harvesting the low-hanging fruit: Kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer
-
J. A. Fagin, R. M. Tuttle, and D. G. Pfister, "Harvesting the low-hanging fruit: kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 6, pp. 2621-2624, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.6
, pp. 2621-2624
-
-
Fagin, J.A.1
Tuttle, R.M.2
Pfister, D.G.3
-
126
-
-
2542458413
-
Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin
-
DOI 10.1210/en.2003-1258
-
F. Furuya, H. Shimura, H. Suzuki et al., "Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin", Endocrinology, vol. 145, no. 6, pp. 2865-2875, 2004. (Pubitemid 38686236)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2865-2875
-
-
Furuya, F.1
Shimura, H.2
Suzuki, H.3
Taki, K.4
Ohta, K.5
Haraguchi, K.6
Onaya, T.7
Endo, T.8
Kobayashi, T.9
-
128
-
-
2542458413
-
Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin
-
DOI 10.1210/en.2003-1258
-
F. Furuya, H. Shimura, H. Suzuki et al., "Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/iodide symporter thyroperoxidase and thyroglobulin", Endocrinology, vol. 145, no. 6, pp. 2865-2875, 2004. (Pubitemid 38686236)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2865-2875
-
-
Furuya, F.1
Shimura, H.2
Suzuki, H.3
Taki, K.4
Ohta, K.5
Haraguchi, K.6
Onaya, T.7
Endo, T.8
Kobayashi, T.9
-
129
-
-
76149087747
-
Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways
-
P. Hou, E. Bojdani, and M. Xing, "Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways", Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 2, pp. 820-828, 2010.
-
(2010)
Journal of Clinical Endocrinology and Metabolism
, vol.95
, Issue.2
, pp. 820-828
-
-
Hou, P.1
Bojdani, E.2
Xing, M.3
-
130
-
-
0034453062
-
Slow release lanreotide in combination with interferon-α2b in the treatment of symptomatic advanced medullary thyroid carcinoma
-
DOI 10.1210/jc.85.3.983
-
G. Vitale, P. Tagliaferri, M. Caraglia et al., "Slow release lanreotide in combination with interferon-α2b in the treatment of symptomatic advanced medullary thyroid carcinoma", Journal of Clinical Endocrinology and Metabolism, vol. 85, no. 3, pp. 983-988, 2000. (Pubitemid 32269337)
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, Issue.3
, pp. 983-988
-
-
Vitale, G.1
Tagliaferri, P.2
Caraglia, M.3
Rampone, E.4
Ciccarelli, A.5
Bianco, A.R.6
Abbruzzese, A.7
Lupoli, G.8
-
131
-
-
67649910150
-
Pilot trial of autologous dendritic cells loaded with tumor lysate (s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma
-
T. Bachleitner-Hofmann, J. Friedl, M. Hassler et al., "Pilot trial of autologous dendritic cells loaded with tumor lysate (s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma", Oncology Reports, vol. 21, no. 6, pp. 1585-1592, 2009.
-
(2009)
Oncology Reports
, vol.21
, Issue.6
, pp. 1585-1592
-
-
Bachleitner-Hofmann, T.1
Friedl, J.2
Hassler, M.3
-
132
-
-
34247362027
-
Methods and goals for the use of in vitro and in vivo chemosensitivity testing
-
DOI 10.1007/s12033-007-9020-9, PII MB352185
-
R. D. Blumenthal and D. M. Goldenberg, "Methods and goals for the use of in vitro and in vivo chemosensitivity testing", Molecular Biotechnology, vol. 35, no. 2, pp. 185-197, 2007. (Pubitemid 46631888)
-
(2007)
Molecular Biotechnology
, vol.35
, Issue.2
, pp. 185-197
-
-
Blumenthal, R.D.1
Goldenberg, D.M.2
-
133
-
-
77954744653
-
Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors
-
T. J. Kruser, D. L. Wheeler, E. A. Armstrong et al., "Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors", Clinical Cancer Research, vol. 16, no. 14, pp. 3639-3647, 2010.
-
(2010)
Clinical Cancer Research
, vol.16
, Issue.14
, pp. 3639-3647
-
-
Kruser, T.J.1
Wheeler, D.L.2
Armstrong, E.A.3
|