-
1
-
-
12644301164
-
3-phosphoinositide-dependent protein kinase-1 (PDK-1): Structural and functional homology with the Drosophila DSTPK61 kinase
-
Alessi D.R., Dean M., Casamayor H., Caudwell F.B., Morrice N., Norman D.G., Gaffney P., Reese C.B., MacDougall C.N., Harbison D., Ashworth A., Bownes M. 3-phosphoinositide-dependent protein kinase-1 (PDK-1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr. Biol. 7:1997;776-789.
-
(1997)
Curr. Biol.
, vol.7
, pp. 776-789
-
-
Alessi, D.R.1
Dean, M.2
Casamayor, H.3
Caudwell, F.B.4
Morrice, N.5
Norman, D.G.6
Gaffney, P.7
Reese, C.B.8
MacDougall, C.N.9
Harbison, D.10
Ashworth, A.11
Bownes, M.12
-
2
-
-
0029043548
-
Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: A molecular switch for control of gene expression
-
Anton M., Graham F.L. Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. J. Virol. 69:1995;4600-4606.
-
(1995)
J. Virol.
, vol.69
, pp. 4600-4606
-
-
Anton, M.1
Graham, F.L.2
-
3
-
-
15644369261
-
Suppresion of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer
-
Cheney I.W., Johnson D.E., Vaillancourt M.T., Avanzini J., Morimoto A., Demers G.W., Wills K.N., Shabram P.W., Bolen J.B., Tavtigian S.V., Bookstein R. Suppresion of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. Cancer Res. 58:1998;2331-2334.
-
(1998)
Cancer Res.
, vol.58
, pp. 2331-2334
-
-
Cheney, I.W.1
Johnson, D.E.2
Vaillancourt, M.T.3
Avanzini, J.4
Morimoto, A.5
Demers, G.W.6
Wills, K.N.7
Shabram, P.W.8
Bolen, J.B.9
Tavtigian, S.V.10
Bookstein, R.11
-
4
-
-
0028963221
-
In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma
-
Clayman G.L., El-Naggar A.K., Roth J.A., Zhang W.-W., Goepfert H., Taylor D.L., Liu T.-J. In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma. Cancer Res. 55:1995;1-6.
-
(1995)
Cancer Res.
, vol.55
, pp. 1-6
-
-
Clayman, G.L.1
El-Naggar, A.K.2
Roth, J.A.3
Zhang, W.-W.4
Goepfert, H.5
Taylor, D.L.6
Liu, T.-J.7
-
5
-
-
0023020262
-
The c-myc oncogene: Its role in transformation and differentiation
-
Cole. The c-myc oncogene: Its role in transformation and differentiation. Annu. Rev. Genet. 20:1986;361-384.
-
(1986)
Annu. Rev. Genet.
, vol.20
, pp. 361-384
-
-
Cole1
-
6
-
-
0032403139
-
Adenoviral transgene expression of MMAC1/PTEN in human glioma cells inhibits Akt activation and induces anoikis
-
Davies M.A., Lu Y., Sano T., Fang X., Tang P., LaPushin R., Koul D., Bookstein R., Stokoe D., Yung W.K.A., Mills G.B., Steck P.A. Adenoviral transgene expression of MMAC1/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res. 58:1998;5285-5290.
-
(1998)
Cancer Res.
, vol.58
, pp. 5285-5290
-
-
Davies, M.A.1
Lu, Y.2
Sano, T.3
Fang, X.4
Tang, P.5
Lapushin, R.6
Koul, D.7
Bookstein, R.8
Stokoe, D.9
Yung, W.K.A.10
Mills, G.B.11
Steck, P.A.12
-
8
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:1998;262-267.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
9
-
-
0023609199
-
Stimulation of c-myc oncogene expression associated with estrogen-induced proliferation of human breast cancer cells
-
Dubik D., Dembinski T.C., Shiu R.P.C. Stimulation of c-myc oncogene expression associated with estrogen-induced proliferation of human breast cancer cells. Cancer Res. 47:1987;6517-6521.
-
(1987)
Cancer Res.
, vol.47
, pp. 6517-6521
-
-
Dubik, D.1
Dembinski, T.C.2
Shiu, R.P.C.3
-
10
-
-
0024253786
-
Transcriptional regulation of c-myc oncogene expression by estrogen in hormone-responsive human breast cancer cells
-
Dubik D., Shiu R.P.C. Transcriptional regulation of c-myc oncogene expression by estrogen in hormone-responsive human breast cancer cells. J. Biol. Chem. 263:1988;12705-12708.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 12705-12708
-
-
Dubik, D.1
Shiu, R.P.C.2
-
11
-
-
0030728479
-
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
-
Furnari F.B., Lin H., Huang H.J.S., Cavenee W.K. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc. Natl. Acad. Sci. USA. 94:1997;12479-12484.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12479-12484
-
-
Furnari, F.B.1
Lin, H.2
Huang, H.J.S.3
Cavenee, W.K.4
-
12
-
-
0019269988
-
Development of a bioassay for human myeloma colony-forming cells
-
Hamburger A.W., Salmon S.E. Development of a bioassay for human myeloma colony-forming cells. Prog. Clin. Biol. Res. 48:1980;23-41.
-
(1980)
Prog. Clin. Biol. Res.
, vol.48
, pp. 23-41
-
-
Hamburger, A.W.1
Salmon, S.E.2
-
13
-
-
0032478271
-
A simplified system for generating recombinant adenovirus
-
He T.-C., Zhou S., da Costa L.T., Yu J., Kinzler K., Vogelstein B. A simplified system for generating recombinant adenovirus. Proc. Natl. Acad. Sci. USA. 95:1998;2509-2514.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2509-2514
-
-
He, T.-C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.5
Vogelstein, B.6
-
14
-
-
0031028730
-
Suppression of c-myc-induced apoptosis by Ras signaling through PI(3)K and PKB
-
Kauffman-Zeh A., Rodriguez-Viciana P., Ulrich E., Gilbert C., Coffer P., Downward J., Evan G. Suppression of c-myc-induced apoptosis by Ras signaling through PI(3)K and PKB. Nature. 385:1997;544-548.
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffman-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
Evan, G.7
-
16
-
-
0027420554
-
Complementation by wild-typr p53 of interleukin-6 effects on M1 cells: Induction of cell cycle exit and cooperativity with c-myc suppression
-
Levy N., Yowish-Rouach Y., Oren M., Kimychi A. Complementation by wild-typr p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression. Mol. Cell. Biol. 13:1993;7942-7952.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7942-7952
-
-
Levy, N.1
Yowish-Rouach, Y.2
Oren, M.3
Kimychi, A.4
-
17
-
-
0031001041
-
TEPI, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
-
Li D.M., Sun H. TEPI, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β Cancer Res. 57:1997;2124-2129.
-
(1997)
Cancer Res.
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
18
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphate gene muluted in human brain, breast and prostate cancer
-
Li J., Yen C., Liaw D., Podsypanina K., Bose S., Wang S., Puc J., Milliaresis C., Rodgers L., McCombie R., Bigner S.H., Giovanella B.C., Ittmann M., Tycko B., Hibshoosh H., Wigler M.H., Parsons R. PTEN, a putative protein tyrosine phosphate gene muluted in human brain, breast and prostate cancer. Science. 275:1997;1943-1946.
-
(1997)
Science
, vol.275
, pp. 1943-1946
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.6
Puc, J.7
Milliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
19
-
-
0032534963
-
The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by AKT/Protein Kinase B oncogene
-
Li J., Simpson L., Takahashi M., Miliaresis C., Myers M.P., Tonks N., Parsons R. The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by AKT/Protein Kinase B oncogene. Cancer Res. 58:1998;5667-5672.
-
(1998)
Cancer Res.
, vol.58
, pp. 5667-5672
-
-
Li, J.1
Simpson, L.2
Takahashi, M.3
Miliaresis, C.4
Myers, M.P.5
Tonks, N.6
Parsons, R.7
-
20
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inheritied breast and thyroid cancer syndrome
-
Liaw D., Marsh D.J., Li J., Dahia P.L.M., Wang S.I., Zheng Z., Bose S., Call K.M., Tsou H.C., Peacocke M., Eng C., Parsons R. Germline mutations of the PTEN gene in Cowden disease, an inheritied breast and thyroid cancer syndrome. Nat. Genet. 16:1997;64-67.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
21
-
-
0032577699
-
The tumor suppressor, PTEN/MMACI, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate
-
Maehama T., Dixon J.E. The tumor suppressor, PTEN/MMACI, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate. J. Biol. Chem. 273:1998;13375-13378.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
22
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
March D.J., Dahia P.L., Liaw D., Parsons R., Gorlin R.J., Eng C. Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat. Genet. 16:1997;333-334.
-
(1997)
Nat. Genet.
, vol.16
, pp. 333-334
-
-
March, D.J.1
Dahia, P.L.2
Liaw, D.3
Parsons, R.4
Gorlin, R.J.5
Eng, C.6
-
24
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers M.P., Stolarov J.P., Eng C., Li J., Wang S.I., Wigler M.H., Parsons R., Tonks M.K. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc. Natl. Acad. Sci. USA. 94:1997;9052-9057.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, M.K.8
-
25
-
-
0025876102
-
Evaluation of c-myc protooncogene in primary human breast carcinomas
-
Pavelic Z.P., Steele P., Preisler H.D. Evaluation of c-myc protooncogene in primary human breast carcinomas. Anticancer Res. 11:1991;1421-1427.
-
(1991)
Anticancer Res.
, vol.11
, pp. 1421-1427
-
-
Pavelic, Z.P.1
Steele, P.2
Preisler, H.D.3
-
26
-
-
0026078478
-
Cloning and characterization of a human c-myc promotor-binding protein
-
Ray R.B., Miller D.M. Cloning and characterization of a human c-myc promotor-binding protein. Mol. Cell. Biol. 11:1991;2154-2161.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 2154-2161
-
-
Ray, R.B.1
Miller, D.M.2
-
27
-
-
0029154558
-
Induction of cell death in murine fibroblasts by a c-myc promoter binding protein
-
Ray R. Induction of cell death in murine fibroblasts by a c-myc promoter binding protein. Cell Growth Differ. 6:1995;1089-1096.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 1089-1096
-
-
Ray, R.1
-
28
-
-
0029101797
-
Human breast carcinoma cells transfected with the gene encoding a c-myc promoter-binding protein (MBP-1) inhibits tumors in nude mice
-
Ray R.B., Steele R., Seftor E., Hendrix M. Human breast carcinoma cells transfected with the gene encoding a c-myc promoter-binding protein (MBP-1) inhibits tumors in nude mice. Cancer Res. 55:1995;3747-3751.
-
(1995)
Cancer Res.
, vol.55
, pp. 3747-3751
-
-
Ray, R.B.1
Steele, R.2
Seftor, E.3
Hendrix, M.4
-
29
-
-
0023673619
-
Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumors with constitutive milk protein gene transcription
-
Schoenenberger C.-A., Andres A.-C., Groner B., van der Valk M., Lemeur M., Gerlinger P. Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumors with constitutive milk protein gene transcription. EMBO J. 7:1988;169-175.
-
(1988)
EMBO J.
, vol.7
, pp. 169-175
-
-
Schoenenberger, C.-A.1
Andres, A.-C.2
Groner, B.3
Van Der Valk, M.4
Lemeur, M.5
Gerlinger, P.6
-
30
-
-
0024456834
-
High levels of c-myc protein in human breast tumors determined by a sensitive ELISA technique
-
Spandidos D.A., Field J.K., Agnantis N.J., Evan G.I., Moore J.P. High levels of c-myc protein in human breast tumors determined by a sensitive ELISA technique. Anticancer Res. 9:1989;821-826.
-
(1989)
Anticancer Res.
, vol.9
, pp. 821-826
-
-
Spandidos, D.A.1
Field, J.K.2
Agnantis, N.J.3
Evan, G.I.4
Moore, J.P.5
-
31
-
-
0026096540
-
Control of c-myc regulation in normal and neoplastic cells
-
Spencer C.A., Gourdine M. Control of c-myc regulation in normal and neoplastic cells. Adv. Cancer Res. 53:1991;1-48.
-
(1991)
Adv. Cancer Res.
, vol.53
, pp. 1-48
-
-
Spencer, C.A.1
Gourdine, M.2
-
32
-
-
17144436629
-
Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck P.A., Pershouse M.A., Jasser S.A., Yung W.K.A, Lin H., Ligon A.H., Langford L.A., Baumgard M.L., Hattier T., Davis T., Frye C., Hu R., Swedlund B., Teng D.H.F., Tavtigian S.V. Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15:1997;356-362.
-
(1997)
Nat. Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.F.14
Tavtigian, S.V.15
-
33
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-triphosphate in the activation of protein kinase B
-
Stokoe D., Stephens L.R., Copeland T., Gaffney P.R., Reese C.B., Painter G.F., Holmes A.B., McCormick F., Hawkins P.T. Dual role of phosphatidylinositol-3,4,5-triphosphate in the activation of protein kinase B. Science. 277:1997;567-570.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
34
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adgesions by tumor suppressor PTEN
-
Tamura M., Gu J., Matsumoto K., Aota S., Parsons R., Yamada K.M. Inhibition of cell migration, spreading, and focal adgesions by tumor suppressor PTEN. Science. 280:1998;1614-1617.
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
|