Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma

International Journal of Cancer

Volumn 104, Issue 3, 2003, Pages 318-327

  Byun, Do Sun ^a   Cho, Kyucheol ^a   Ryu, Byung Kyu ^a   Lee, Min Goo ^a   Park, Jae Il ^a   Chae, Kwon Seok ^a   Kim, Hyo Jong ^a   Chi, Sung Gil ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

AKT; Gastric cancer; Gene amplification; Loss of heterozygosity; PIK3CA; PTEN

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PIK3CA PROTEIN; UNCLASSIFIED DRUG;

ADVANCED CANCER; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DNA POLYMORPHISM; EARLY CANCER; GENE AMPLIFICATION; GENE MUTATION; GENE SILENCING; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; PSEUDOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; SLOT BLOT HYBRIDIZATION; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; TUMOR DIFFERENTIATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; ADENOMA; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; DNA, NEOPLASM; GENE AMPLIFICATION; GENE SILENCING; HAMARTOMA; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MUTATION; NEOPLASM STAGING; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PSEUDOGENES; PTEN PHOSPHOHYDROLASE; RNA, MESSENGER; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0037431435     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10962     Document Type: Article

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