Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self-administration

Neuroscience Letters

Volumn 452, Issue 2, 2009, Pages 167-171

  Ghasemzadeh, M Behnam ^a   Vasudevan, Preethi ^a   Mueller, Christopher ^a   Seubert, Chad ^a   Mantsch, John R ^a  

^a MARQUETTE UNIVERSITY   (United States)

Author keywords

Actin; Dorsal striatum; Nucleus accumbens; PSD 95; Receptor trafficking; Scaffolding protein

Indexed keywords

ACTIN; COCAINE; METABOTROPIC RECEPTOR 5; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN HOMER; SODIUM CHLORIDE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN SYNAPTOSOME; CONTROLLED STUDY; CORPUS STRIATUM; DRUG SELF ADMINISTRATION; DRUG WITHDRAWAL; NEUROADAPTATION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REINFORCEMENT; SYNAPSE;

ACTINS; ADAPTATION, PHYSIOLOGICAL; ANIMALS; BRAIN; BRAIN CHEMISTRY; CARRIER PROTEINS; COCAINE; COCAINE-RELATED DISORDERS; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DOPAMINE UPTAKE INHIBITORS; EXTINCTION, PSYCHOLOGICAL; GLUTAMIC ACID; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; NEURONAL PLASTICITY; NUCLEUS ACCUMBENS; PRESYNAPTIC TERMINALS; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; SELF ADMINISTRATION; SYNAPTIC TRANSMISSION; SYNAPTOSOMES;

EID: 60249091229     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.12.028     Document Type: Article

References (36)

1. Anderson S.M., Famous K.R., Sadri-Vakili G., Kumaresan V., Schmidt H.D., Bass C.E., Terwilliger E.F., Cha J.J., and Pierce R.C. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nat. Neurosci. 11 (2008) 344-353
2. Ango F., Robbe D., Tu J.C., Xiao B., Worley P.F., Pin J.P., Bockaert J., and Fagni L. Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Mol. Cell. Neurosci. 20 (2002) 323-329
3. Ary A.W., and Szumlinski K.K. Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: a two-species comparison. Brain Res. 1184 (2007) 295-305
4. Bäckström P., Bachteler D., Koch S., Hyytiä P., and Spanagel R. mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior. Neuropsychopharmacology 29 (2004) 921-928
5. Bouton M.E. Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. Biol. Psychiatry 52 (2002) 976-986
6. Chiamulera C., Epping-Jordan M.P., Zocchi A., Marcon C., Cottiny C., Tacconi S., Corsi M., Orzi F., and Conquet F. Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice. Nat. Neurosci. 4 (2001) 873-874
7. Conrad K.I., Tseng K.Y., Uejima J.L., Reimers J.M., Heng L., Shaham Y., Marinelli M., and Wolf M. Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving. Nature 454 (2008) 118-124
8. Cornish J.L., and Kalivas P.W. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. J. Neurosci. 20 (2000) 89RC (1-5)
9. Dunah A.W., and Standaert D.G. Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane. J. Neurosci. 21 (2001) 5546-5558
10. Ehrlich I., and Malinow R. Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. J. Neurosci. 24 (2004) 916-927
11. Fuchs R.A., Branham R.K., and See R.E. Different neural substrates mediate cocaine seeking after abstinence versus extinction training: a critical role for the dorsolateral caudate-putamen. J. Neurosci. 26 (2006) 3584-3588
12. Gass J.T., Osborne M.P., Watson N.L., Brown J.L., and Olive M.F. mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats. Neuropsychopharmacology (2008) 10.1038/npp.2008.140
13. Ghasemzadeh M.B., Permenter L.K., Lake R., Worley P.F., and Kalivas P.W. Homer1 Proteins and AMPA receptors modulate cocaine-induced behavioral plasticity. Eur. J. Neurosci. 18 (2003) 1645-1651
14. Hunt C.A., Schenker L.J., and Kennedy M.B. PSD95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses. J. Neurosci. 16 (1996) 1380-1388
15. Kalivas P.W., and McFarland K. Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology 168 (2003) 44-56
16. Kalivas P.W., and Volkow N.D. The neural basis of addiction: a pathology of motivation and choice. Am. J. Psychiatry 162 (2005) 1403-1413
17. Kenny P.J., Boutrel B., Gasparini F., Koob G.F., and Markou A. Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology 179 (2005) 247-254
18. Koob G., Kreek M.J., and Stress J. Dysregulation of drug reward pathways, and the transition to drug dependence. Am. J. Psychiatry 164 (2007) 1149-1159
19. Kornau H.C., Schenker L.T., Kennedy M.B., and Seeburg P.H. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269 (1995) 1737-1740
20. Mantsch J.R., Baker D.A., Serge J.P., Hoks M.A., Francis D.M., and Katz E.S. Surgical adrenalectomy and diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions. Neuropsychopharmacology 33 (2008) 814-826
21. Paterson N.E., Semenova S., Gasparini F., and Markou A. The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. Psychopharmacology (Berl.) 167 (2003) 257-264
22. Peters J., LaLumiere R.T., and Kalivas P.W. Infralimbic cortex is responsible for inhibiting cocaine seeking in extinguished rats. J. Neurosci. 28 (2008) 6046-6053
23. Ping A., Xi J., Prasad B.M., Wang M.H., and Kruzich P.J. Contributions of nucleus accumbens core and shell GluR1 containing AMPA receptors in AMPA- and cocaine-primed reinstatement of cocaine-seeking behavior. Brain Res. 1215 (2008) 173-182
24. Platt D.M., Rowlett J.K., and Spealman R.D. Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: comparison with dizocilpine. Psychopharmacology 200 (2008) 167-176
25. Schnell E., Sizemore M., Karimzadegan S., Chen L., Bredt D.S., and Nicoll R.A. Direct interactions between PSD95 and stargazing control synaptic AMPA receptor number. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 13902-13907
26. Seemann J., Jokitalo E.J., and Warren G. The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo. Mol. Biol. Cell 11 (2000) 635-645
27. Self D.W., Choi K., Simmons D., Walker J.R., and Smagula C.S. Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration. Learning Memory 11 (2004) 648-657
28. Sutton M.A., Schmidt E.F., Choi K., Schad C.A., Whisler K., Simmons D., Karanian D.A., Monteggia L.M., Neve R.L., and Self D.W. Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour. Nature 421 (2003) 70-75
29. Swanson C.J., Baker D.A., Carson D., Worley P.F., and Kalivas P.W. Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for homer. J. Neurosci. 21 (2001) 9043-9052
30. Szumlinski K.K., Dehoff M.H., Kang S.H., Frys K.A., Lominac K.D., Klugmann M., Rohrer J., Griffin III W., Toda S., Champtiaux N.P., Berry T., Tu J.C., Shealy S.E., During M.J., Middaugh L.D., Worley P.F., and Kalivas P.W. Homer proteins regulate sensitivity to cocaine. Neuron 43 (2004) 401-413
31. Tessari M., Pilla M., Andreoli M., Hutcheson D.M., and Heidbreder C.A. Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking. Eur. J. Pharmacol. 499 (2004) 121-133
32. Toda S., Shen H.W., Peters J., Cagle S., and Kalivas P.W. Cocaine increases actin cycling: effects in the reinstatement model of drug seeking. J. Neurosci. 26 (2006) 1579-1587
33. Tu J.C., Xiao B., Naisbitt S., Yuan J.P., Petralia R.S., Brakeman P., Doan A., Aakalu V.K., Lanahan A.A., Sheng M., and Worley P.F. Coupling of mGluR/Homer and PSD-95 complexes by the shank family of postsynaptic density proteins. Neuron 23 (1999) 583-592
34. Wiedenmann B., and Franke W.W. Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 41 (1985) 1017-1028
35. Williams D.B. Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum. J. Cell. Sci. 119 (2006) 615-623
36. Xiao B., Tu J.C., Petralia R.S., Yuan J.P., Doan A., Breder C.D., Ruggiero A., Lanahan A.A., Wenthold R.J., and Worley P.F. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related synaptic proteins. Neuron 21 (1998) 707-716