Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum

Molecular Brain Research

Volumn 109, Issue 1-2, 2002, Pages 168-178

  Malherbe, Pari ^a   Kew, James N C ^a,c   Richards, J Grayson ^a   Knoflach, Frédéric ^a   Kratzeisen, Claudia ^a   Zenner, Marie Thérèse ^a   Faull, Richard L M ^b   Kemp, John A ^a   Mutel, Vincent ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Desensitization; Fluorometric imaging plate reader (FLIPR); G protein coupled inwardly rectifying K+ channel activity (GIRK); MGlu receptor; Protein kinase C (PKC); Splice variant

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 (CARBOXYCYCLOPROPYL)GLYCINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; CALCIUM ION; GLUTAMIC ACID; INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOPROTEIN; MESSENGER RNA; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; METHYLPHENYLETHYNYLPYRIDINE; PROTEIN KINASE C; QUISQUALIC ACID; UNCLASSIFIED DRUG;

ADULT; AGED; ALTERNATIVE RNA SPLICING; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CARBOXY TERMINAL SEQUENCE; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DNA LIBRARY; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RECEPTOR AFFINITY;

AGED; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CELL LINE; CEREBELLUM; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; FEMALE; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN ISOFORMS; QUISQUALIC ACID; RECEPTORS, METABOTROPIC GLUTAMATE; SEQUENCE ALIGNMENT;

EID: 0037203324     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00557-0     Document Type: Article

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