Loss of endoplasmic reticulum Ca2+ homeostasis: Contribution to neuronal cell death during cerebral ischemia

Acta Pharmacologica Sinica

Volumn 34, Issue 1, 2013, Pages 49-59

  Bodalia, Ankur ^a   Li, Hongbin ^b   Jackson, Michael F ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Ca2+homeostasis; ER stress; IP3R; ischemia; neuronal cell death; RyR; SERCA; unfolded protein response(UPR)

Indexed keywords

CALCIUM ION; INOSITOL TRIPHOSPHATE RECEPTOR; RECEPTOR; RYANODINE RECEPTOR 1; RYANODINE RECEPTOR 2; RYANODINE RECEPTOR 3; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL DEATH; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; NERVE CELL NECROSIS; REVIEW; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CALCIUM; CELL DEATH; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMANS; NEURONS; UNFOLDED PROTEIN RESPONSE;

EID: 84872079384     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.139     Document Type: Review

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