메뉴 건너뛰기




Volumn 10, Issue 1, 2009, Pages 103-115

Dantrolene: Mechanisms of Neuroprotection and Possible Clinical Applications in the Neurointensive Care Unit

Author keywords

Calcium; Dantrolene; Neuroprotection, ischemia, seizure; Ryanodine receptor; Sarco endoplasmic reticulum; Serotonin; Trauma; Vasospasm

Indexed keywords

CALCIUM; CENTRAL MUSCLE RELAXANT; DANTROLENE; RYANODINE RECEPTOR;

EID: 63249121147     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-008-9133-4     Document Type: Review
Times cited : (62)

References (115)
  • 1
    • 0016439307 scopus 로고
    • Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium
    • Harrison GG. Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium. Br J Anaesth. 1975;47(1):62–5. doi:10.1093/bja/47.1.62. DOI: 10.1093/bja/47.1.62
    • (1975) Br J Anaesth , vol.47 , Issue.1 , pp. 62-65
    • Harrison, G.G.1
  • 2
    • 11144357133 scopus 로고    scopus 로고
    • Dantrolene reduces the threshold and gain for shivering
    • Table of contents
    • Lin CM, Neeru S, Doufas AG, et al. Dantrolene reduces the threshold and gain for shivering. Anesth Analg. 2004;98(5):1318–24. doi:10.1213/01.ANE.0000108968.21212.D7. Table of contents. DOI: 10.1213/01.ANE.0000108968.21212.D7
    • (2004) Anesth Analg , vol.98 , Issue.5 , pp. 1318-1324
    • Lin, C.M.1    Neeru, S.2    Doufas, A.G.3
  • 3
    • 0019420878 scopus 로고
    • Treatment of heat stroke with dantrolene
    • Lydiatt JS, Hill GE. Treatment of heat stroke with dantrolene. JAMA. 1981;246(1):41–2. doi:10.1001/jama.246.1.41. DOI: 10.1001/jama.246.1.41
    • (1981) JAMA , vol.246 , Issue.1 , pp. 41-42
    • Lydiatt, J.S.1    Hill, G.E.2
  • 4
    • 13844281633 scopus 로고    scopus 로고
    • Clinical review: treatment of heat stroke: should dantrolene be considered?
    • Hadad E, Cohen-Sivan Y, Heled Y, Epstein Y. Clinical review: treatment of heat stroke: should dantrolene be considered? Crit Care. 2005;9(1):86–91. doi:10.1186/cc2923. DOI: 10.1186/cc2923
    • (2005) Crit Care , vol.9 , Issue.1 , pp. 86-91
    • Hadad, E.1    Cohen-Sivan, Y.2    Heled, Y.3    Epstein, Y.4
  • 5
    • 33646871323 scopus 로고    scopus 로고
    • Acute toxic effects of ‘Ecstasy’ (MDMA) and related compounds: overview of pathophysiology and clinical management
    • Hall AP, Henry JA. Acute toxic effects of ‘Ecstasy’ (MDMA) and related compounds: overview of pathophysiology and clinical management. Br J Anaesth. 2006;96(6):678–85. doi:10.1093/bja/ael078. DOI: 10.1093/bja/ael078
    • (2006) Br J Anaesth , vol.96 , Issue.6 , pp. 678-685
    • Hall, A.P.1    Henry, J.A.2
  • 6
    • 0028333941 scopus 로고
    • Sertraline-phenelzine drug interaction: a serotonin syndrome reaction
    • PID: 7919561, COI: 1:STN:280:DyaK2M%2Fgtlantw%3D%3D
    • Graber MA, Hoehns TB, Perry PJ. Sertraline-phenelzine drug interaction: a serotonin syndrome reaction. Ann Pharmacother. 1994;28(6):732–5.
    • (1994) Ann Pharmacother , vol.28 , Issue.6 , pp. 732-735
    • Graber, M.A.1    Hoehns, T.B.2    Perry, P.J.3
  • 7
    • 0025972677 scopus 로고
    • 2+ release from intracellular stores in cultured cerebral cortical neurons
    • 2+ release from intracellular stores in cultured cerebral cortical neurons. J Neurochem. 1991;56(3):1075–8. doi:10.1111/j.1471-4159.1991.tb02031.x. DOI: 10.1111/j.1471-4159.1991.tb02031.x
    • (1991) J Neurochem , vol.56 , Issue.3 , pp. 1075-1078
    • Frandsen, A.1    Schousboe, A.2
  • 8
    • 0025176813 scopus 로고
    • Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia
    • MacLennan DH, Duff C, Zorzato F, et al. Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia. Nature. 1990;343(6258):559–61. doi:10.1038/343559a0. DOI: 10.1038/343559a0
    • (1990) Nature , vol.343 , Issue.6258 , pp. 559-561
    • MacLennan, D.H.1    Duff, C.2    Zorzato, F.3
  • 9
    • 0024372718 scopus 로고
    • Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum
    • Marks AR, Tempst P, Hwang KS, et al. Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum. Proc Natl Acad Sci USA. 1989;86(22):8683–7. doi:10.1073/pnas.86.22.8683. DOI: 10.1073/pnas.86.22.8683
    • (1989) Proc Natl Acad Sci USA , vol.86 , Issue.22 , pp. 8683-8687
    • Marks, A.R.1    Tempst, P.2    Hwang, K.S.3
  • 10
    • 0036147144 scopus 로고    scopus 로고
    • Modulation of intracellular calcium-release channels by calmodulin
    • Balshaw DM, Yamaguchi N, Meissner G. Modulation of intracellular calcium-release channels by calmodulin. J Membr Biol. 2002;185(1):1–8. doi:10.1007/s00232-001-0111-4. DOI: 10.1007/s00232-001-0111-4
    • (2002) J Membr Biol , vol.185 , Issue.1 , pp. 1-8
    • Balshaw, D.M.1    Yamaguchi, N.2    Meissner, G.3
  • 11
    • 0028925223 scopus 로고
    • The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues
    • Giannini G, Conti A, Mammarella S, Scrobogna M, Sorrentino V. The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. J Cell Biol. 1995;128(5):893–904. doi:10.1083/jcb.128.5.893. DOI: 10.1083/jcb.128.5.893
    • (1995) J Cell Biol , vol.128 , Issue.5 , pp. 893-904
    • Giannini, G.1    Conti, A.2    Mammarella, S.3    Scrobogna, M.4    Sorrentino, V.5
  • 12
    • 0030777358 scopus 로고    scopus 로고
    • 2+ release by direct and specific action at skeletal muscle ryanodine receptors
    • 2+ release by direct and specific action at skeletal muscle ryanodine receptors. J Biol Chem. 1997;272(43):26965–71. doi:10.1074/jbc.272.43.26965. DOI: 10.1074/jbc.272.43.26965
    • (1997) J Biol Chem , vol.272 , Issue.43 , pp. 26965-26971
    • Fruen, B.R.1    Mickelson, J.R.2    Louis, C.F.3
  • 13
    • 0035958043 scopus 로고    scopus 로고
    • 2+ release channels. Molecular mechanism and isoform selectivity
    • PID: 11278295, COI: 1:CAS:528:DC%2BD3MXjt12kurk%3D
    • 2+ release channels. Molecular mechanism and isoform selectivity. J Biol Chem. 2001;276(17):13810–6.
    • (2001) J Biol Chem , vol.276 , Issue.17 , pp. 13810-13816
    • Zhao, F.1    Li, P.2    Chen, S.R.3    Louis, C.F.4    Fruen, B.R.5
  • 14
    • 0029157640 scopus 로고
    • 2+ release
    • 2+ release. Trends Pharmacol Sci. 1995;16(10):356–9. doi:10.1016/S0165-6147(00)89070-7. DOI: 10.1016/S0165-6147(00)89070-7
    • (1995) Trends Pharmacol Sci , vol.16 , Issue.10 , pp. 356-359
    • Mody, I.1    MacDonald, J.F.2
  • 15
    • 0029805317 scopus 로고    scopus 로고
    • Dantrolene is cytoprotective in two models of neuronal cell death
    • PID: 8931471, COI: 1:CAS:528:DyaK28Xnt1Wjsrs%3D
    • Wei H, Perry DC. Dantrolene is cytoprotective in two models of neuronal cell death. J Neurochem. 1996;67(6):2390–8.
    • (1996) J Neurochem , vol.67 , Issue.6 , pp. 2390-2398
    • Wei, H.1    Perry, D.C.2
  • 16
    • 0032588215 scopus 로고    scopus 로고
    • Seizure-induced cell death produced by repeated tetanic stimulation in vitro: possible role of endoplasmic reticulum calcium stores
    • PID: 10368420, COI: 1:CAS:528:DyaK1MXktlSjsLo%3D
    • Pelletier MR, Wadia JS, Mills LR, Carlen PL. Seizure-induced cell death produced by repeated tetanic stimulation in vitro: possible role of endoplasmic reticulum calcium stores. J Neurophysiol. 1999;81(6):3054–64.
    • (1999) J Neurophysiol , vol.81 , Issue.6 , pp. 3054-3064
    • Pelletier, M.R.1    Wadia, J.S.2    Mills, L.R.3    Carlen, P.L.4
  • 17
    • 0036338083 scopus 로고    scopus 로고
    • Determinants of ictal epileptiform patterns in the hippocampal slice
    • Rutecki PA, Sayin U, Yang Y, Hadar E. Determinants of ictal epileptiform patterns in the hippocampal slice. Epilepsia. 2002;43(Suppl 5):179–83. doi:10.1046/j.1528-1157.43.s.5.34.x. DOI: 10.1046/j.1528-1157.43.s.5.34.x
    • (2002) Epilepsia , vol.43 , pp. 179-183
    • Rutecki, P.A.1    Sayin, U.2    Yang, Y.3    Hadar, E.4
  • 18
    • 0036126440 scopus 로고    scopus 로고
    • Role of RyRs and IP3 receptors after traumatic injury to spinal cord white matter
    • Thorell WE, Leibrock LG, Agrawal SK. Role of RyRs and IP3 receptors after traumatic injury to spinal cord white matter. J Neurotrauma. 2002;19(3):335–42. doi:10.1089/089771502753594909. DOI: 10.1089/089771502753594909
    • (2002) J Neurotrauma , vol.19 , Issue.3 , pp. 335-342
    • Thorell, W.E.1    Leibrock, L.G.2    Agrawal, S.K.3
  • 19
    • 0016699991 scopus 로고
    • Evaluation of a muscle relaxant: dantrolene sodium (Dantrium)
    • Dykes MH. Evaluation of a muscle relaxant: dantrolene sodium (Dantrium). JAMA. 1975;231(8):862–4. doi:10.1001/jama.231.8.862. DOI: 10.1001/jama.231.8.862
    • (1975) JAMA , vol.231 , Issue.8 , pp. 862-864
    • Dykes, M.H.1
  • 20
    • 0016251788 scopus 로고
    • Pharmacology of dantrolene sodium in children
    • PID: 4853611, COI: 1:STN:280:DyaE2czgsFGmtA%3D%3D
    • Lietman PS, Haslam RH, Walcher JR. Pharmacology of dantrolene sodium in children. Arch Phys Med Rehabil. 1974;55(8):388–92.
    • (1974) Arch Phys Med Rehabil , vol.55 , Issue.8 , pp. 388-392
    • Lietman, P.S.1    Haslam, R.H.2    Walcher, J.R.3
  • 21
    • 0018644090 scopus 로고
    • Relationship between plasma concentration and effect of dantrolene sodium in man
    • Meyler WJ, Mols-Thurkow HW, Wesseling H. Relationship between plasma concentration and effect of dantrolene sodium in man. Eur J Clin Pharmacol. 1979;16(3):203–9. doi:10.1007/BF00562062. DOI: 10.1007/BF00562062
    • (1979) Eur J Clin Pharmacol , vol.16 , Issue.3 , pp. 203-209
    • Meyler, W.J.1    Mols-Thurkow, H.W.2    Wesseling, H.3
  • 22
    • 0020521043 scopus 로고
    • Dantrolene dose response in awake man: implications for management of malignant hyperthermia
    • Flewellen EH, Nelson TE, Jones WP, Arens JF, Wagner DL. Dantrolene dose response in awake man: implications for management of malignant hyperthermia. Anesthesiology. 1983;59(4):275–80. doi:10.1097/00000542-198310000-00002. DOI: 10.1097/00000542-198310000-00002
    • (1983) Anesthesiology , vol.59 , Issue.4 , pp. 275-280
    • Flewellen, E.H.1    Nelson, T.E.2    Jones, W.P.3    Arens, J.F.4    Wagner, D.L.5
  • 23
    • 0018103066 scopus 로고
    • Muscle relaxant properties of the identified metabolites of dantrolene
    • Ellis KO, Wessels FL. Muscle relaxant properties of the identified metabolites of dantrolene. Naunyn Schmiedebergs Arch Pharmacol. 1978;301(3):237–40. doi:10.1007/BF00507042. DOI: 10.1007/BF00507042
    • (1978) Naunyn Schmiedebergs Arch Pharmacol , vol.301 , Issue.3 , pp. 237-240
    • Ellis, K.O.1    Wessels, F.L.2
  • 24
    • 0018837495 scopus 로고
    • Nitrofurantoin and dantrolene; liver and lung
    • PID: 7396303, COI: 1:STN:280:DyaL3c3ktVahtg%3D%3D
    • Faling LJ, Petusevsky ML, Snider GL. Nitrofurantoin and dantrolene; liver and lung. Ann Intern Med. 1980;93(1):151.
    • (1980) Ann Intern Med , vol.93 , Issue.1 , pp. 151
    • Faling, L.J.1    Petusevsky, M.L.2    Snider, G.L.3
  • 25
    • 0025025778 scopus 로고
    • Dantrolene sodium and hepatic injury
    • PID: 2392230, COI: 1:STN:280:DyaK3czmtlCisw%3D%3D
    • Chan CH. Dantrolene sodium and hepatic injury. Neurology. 1990;40(9):1427–32.
    • (1990) Neurology , vol.40 , Issue.9 , pp. 1427-1432
    • Chan, C.H.1
  • 26
    • 0021136668 scopus 로고
    • Hepatotoxicological evaluation of dantrolene sodium
    • Durham JA, Gandolfi AJ, Bentley JB. Hepatotoxicological evaluation of dantrolene sodium. Drug Chem Toxicol. 1984;7(1):23–40. doi:10.3109/01480548409014171. DOI: 10.3109/01480548409014171
    • (1984) Drug Chem Toxicol , vol.7 , Issue.1 , pp. 23-40
    • Durham, J.A.1    Gandolfi, A.J.2    Bentley, J.B.3
  • 27
    • 0027333181 scopus 로고
    • Protective effect of dantrolene sodium on carbon tetrachloride induced liver injury in the rat
    • PID: 8303092, COI: 1:CAS:528:DyaK2cXisFagug%3D%3D
    • Yamagishi F, Komoda T, Ohnishi K, Itoh S. Protective effect of dantrolene sodium on carbon tetrachloride induced liver injury in the rat. Res Commun Chem Pathol Pharmacol. 1993;82(2):237–40.
    • (1993) Res Commun Chem Pathol Pharmacol , vol.82 , Issue.2 , pp. 237-240
    • Yamagishi, F.1    Komoda, T.2    Ohnishi, K.3    Itoh, S.4
  • 28
    • 0022394169 scopus 로고
    • Comparison of dantrolene sodium with erythromycin estolate using primary cultures of rat hepatocytes
    • Sorensen EM, Acosta D. Comparison of dantrolene sodium with erythromycin estolate using primary cultures of rat hepatocytes. Drug Chem Toxicol. 1985;8(4):219–37. doi:10.3109/01480548509038647. DOI: 10.3109/01480548509038647
    • (1985) Drug Chem Toxicol , vol.8 , Issue.4 , pp. 219-237
    • Sorensen, E.M.1    Acosta, D.2
  • 29
    • 84943435101 scopus 로고
    • Pleuropericardial reaction to treatment with dantrolene
    • Petusevsky ML, Faling LJ, Rocklin RE, et al. Pleuropericardial reaction to treatment with dantrolene. JAMA. 1979;242(25):2772–4. doi:10.1001/jama.242.25.2772. DOI: 10.1001/jama.242.25.2772
    • (1979) JAMA , vol.242 , Issue.25 , pp. 2772-2774
    • Petusevsky, M.L.1    Faling, L.J.2    Rocklin, R.E.3
  • 30
    • 0028343758 scopus 로고
    • Pleural effusion associated with chronic dantrolene administration
    • PID: 8068995, COI: 1:STN:280:DyaK2czkvVWmsQ%3D%3D
    • Mahoney JM, Bachtel MD. Pleural effusion associated with chronic dantrolene administration. Ann Pharmacother. 1994;28(5):587–9.
    • (1994) Ann Pharmacother , vol.28 , Issue.5 , pp. 587-589
    • Mahoney, J.M.1    Bachtel, M.D.2
  • 31
    • 0035347787 scopus 로고    scopus 로고
    • Eosinophilic pleural effusion due to dantrolene: resolution with steroid therapy
    • PID: 11372801, COI: 1:STN:280:DC%2BD3M3ovFyhtw%3D%3D
    • Felz MW, Haviland-Foley DJ. Eosinophilic pleural effusion due to dantrolene: resolution with steroid therapy. South Med J. 2001;94(5):502–4.
    • (2001) South Med J , vol.94 , Issue.5 , pp. 502-504
    • Felz, M.W.1    Haviland-Foley, D.J.2
  • 32
    • 0021337401 scopus 로고
    • Hyperkalemia and cardiovascular collapse after verapamil and dantrolene administration in swine
    • Saltzman LS, Kates RA, Corke BC, Norfleet EA, Heath KR. Hyperkalemia and cardiovascular collapse after verapamil and dantrolene administration in swine. Anesth Analg. 1984;63(5):473–8. doi:10.1213/00000539-198405000-00001. DOI: 10.1213/00000539-198405000-00001
    • (1984) Anesth Analg , vol.63 , Issue.5 , pp. 473-478
    • Saltzman, L.S.1    Kates, R.A.2    Corke, B.C.3    Norfleet, E.A.4    Heath, K.R.5
  • 33
    • 0030065257 scopus 로고    scopus 로고
    • Cardiac implications of amlodipine-dantrolene combinations
    • PID: 8665636, COI: 1:STN:280:DyaK283ktV2qsA%3D%3D
    • Freysz M, Timour Q, Bernaud C, Bertrix L, Faucon G. Cardiac implications of amlodipine-dantrolene combinations. Can J Anaesth. 1996;43(1):50–5.
    • (1996) Can J Anaesth , vol.43 , Issue.1 , pp. 50-55
    • Freysz, M.1    Timour, Q.2    Bernaud, C.3    Bertrix, L.4    Faucon, G.5
  • 34
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H, Drejer J, Schousboe A, Diemer NH. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem. 1984;43(5):1369–74. doi:10.1111/j.1471-4159.1984.tb05396.x. DOI: 10.1111/j.1471-4159.1984.tb05396.x
    • (1984) J Neurochem , vol.43 , Issue.5 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 35
    • 0030044586 scopus 로고    scopus 로고
    • Mechanisms of cerebral ischemia: intracellular cascades and therapeutic interventions
    • Small DL, Buchan AM. Mechanisms of cerebral ischemia: intracellular cascades and therapeutic interventions. J Cardiothorac Vasc Anesth. 1996;10(1):139–46. doi:10.1016/S1053-0770(96)80189-3. DOI: 10.1016/S1053-0770(96)80189-3
    • (1996) J Cardiothorac Vasc Anesth , vol.10 , Issue.1 , pp. 139-146
    • Small, D.L.1    Buchan, A.M.2
  • 36
    • 0031953601 scopus 로고    scopus 로고
    • Calcium in ischemic cell death
    • PID: 9506616, COI: 1:STN:280:DyaK1c7msFClsg%3D%3D
    • Kristian T, Siesjo BK. Calcium in ischemic cell death. Stroke. 1998;29(3):705–18.
    • (1998) Stroke , vol.29 , Issue.3 , pp. 705-718
    • Kristian, T.1    Siesjo, B.K.2
  • 37
    • 0021881244 scopus 로고
    • Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo
    • Somlyo AP, Bond M, Somlyo AV. Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo. Nature. 1985;314(6012):622–5. doi:10.1038/314622a0. DOI: 10.1038/314622a0
    • (1985) Nature , vol.314 , Issue.6012 , pp. 622-625
    • Somlyo, A.P.1    Bond, M.2    Somlyo, A.V.3
  • 38
    • 0023069451 scopus 로고
    • Intracellular calcium homeostasis
    • Carafoli E. Intracellular calcium homeostasis. Annu Rev Biochem. 1987;56:395–433. doi:10.1146/annurev.bi.56.070187.002143. DOI: 10.1146/annurev.bi.56.070187.002143
    • (1987) Annu Rev Biochem , vol.56 , pp. 395-433
    • Carafoli, E.1
  • 39
    • 0031048249 scopus 로고    scopus 로고
    • Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil
    • Kohno K, Higuchi T, Ohta S, Kohno K, Kumon Y, Sakaki S. Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil. Neurosci Lett. 1997;224(1):17–20. doi:10.1016/S0304-3940(97)13459-0. DOI: 10.1016/S0304-3940(97)13459-0
    • (1997) Neurosci Lett , vol.224 , Issue.1 , pp. 17-20
    • Kohno, K.1    Higuchi, T.2    Ohta, S.3    Kohno, K.4    Kumon, Y.5    Sakaki, S.6
  • 40
    • 0038464650 scopus 로고    scopus 로고
    • Regulation of cell death: the calcium-apoptosis link
    • COI: 1:CAS:528:DC%2BD3sXltVWnu7g%3D
    • Orrenius S, Zhivotovsky B, Nicotera P. Regulation of cell death: the calcium-apoptosis link. Nat Rev. 2003;4(7):552–65. DOI: 10.1038/nrm1150
    • (2003) Nat Rev , vol.4 , Issue.7 , pp. 552-565
    • Orrenius, S.1    Zhivotovsky, B.2    Nicotera, P.3
  • 41
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
    • Kaufman RJ. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 1999;13(10):1211–33. doi:10.1101/gad.13.10.1211. DOI: 10.1101/gad.13.10.1211
    • (1999) Genes Dev , vol.13 , Issue.10 , pp. 1211-1233
    • Kaufman, R.J.1
  • 42
    • 0032780022 scopus 로고    scopus 로고
    • The cellular response to protein misfolding in the endoplasmic reticulum
    • PID: 10440230, COI: 1:CAS:528:DyaK1MXltVKmtL8%3D
    • Welihinda AA, Tirasophon W, Kaufman RJ. The cellular response to protein misfolding in the endoplasmic reticulum. Gene Expr. 1999;7(4–6):293–300.
    • (1999) Gene Expr , vol.7 , Issue.4-6 , pp. 293-300
    • Welihinda, A.A.1    Tirasophon, W.2    Kaufman, R.J.3
  • 43
    • 0043238675 scopus 로고    scopus 로고
    • The biochemistry of neuronal necrosis: rogue biology?
    • COI: 1:CAS:528:DC%2BD3sXlvV2itLc%3D
    • Syntichaki P, Tavernarakis N. The biochemistry of neuronal necrosis: rogue biology? Nat Rev. 2003;4(8):672–84. DOI: 10.1038/nrn1174
    • (2003) Nat Rev , vol.4 , Issue.8 , pp. 672-684
    • Syntichaki, P.1    Tavernarakis, N.2
  • 44
    • 19344378952 scopus 로고    scopus 로고
    • The effects of ruthenium red, dantrolene and nimodipine, alone or in combination, in NMDA induced neurotoxicity of cerebellar granular cell culture of rats
    • Duzenli S, Bakuridze K, Gepdiremen A. The effects of ruthenium red, dantrolene and nimodipine, alone or in combination, in NMDA induced neurotoxicity of cerebellar granular cell culture of rats. Toxicol In Vitro. 2005;19(5):589–94. doi:10.1016/j.tiv.2005.03.007. DOI: 10.1016/j.tiv.2005.03.007
    • (2005) Toxicol In Vitro , vol.19 , Issue.5 , pp. 589-594
    • Duzenli, S.1    Bakuridze, K.2    Gepdiremen, A.3
  • 46
    • 0027283953 scopus 로고
    • 2+ responses to N-Methyl-D-aspartate and depolarization in cerebellar granule cells
    • PID: 8336152, COI: 1:CAS:528:DyaK3sXlsFaltbc%3D
    • 2+ responses to N-Methyl-D-aspartate and depolarization in cerebellar granule cells. J Neurochem. 1993;61(2):760–3.
    • (1993) J Neurochem , vol.61 , Issue.2 , pp. 760-763
    • Simpson, P.B.1    Challiss, R.A.2    Nahorski, S.R.3
  • 47
    • 52949123294 scopus 로고    scopus 로고
    • Protective effect of retinal ischemia by blockers of voltage-dependent calcium channels and intracellular calcium stores
    • Massote PD, Pinheiro AC, Fonseca CG, et al. Protective effect of retinal ischemia by blockers of voltage-dependent calcium channels and intracellular calcium stores. Cell Mol Neurobiol. 2008.
    • (2008) Cell Mol Neurobiol
    • Massote, P.D.1    Pinheiro, A.C.2    Fonseca, C.G.3
  • 48
    • 0026572466 scopus 로고
    • Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons
    • Frandsen A, Schousboe A. Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc Natl Acad Sci USA. 1992;89(7):2590–4. doi:10.1073/pnas.89.7.2590. DOI: 10.1073/pnas.89.7.2590
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.7 , pp. 2590-2594
    • Frandsen, A.1    Schousboe, A.2
  • 49
    • 0027074763 scopus 로고
    • 2+ prevents neurotoxicity
    • 2+ prevents neurotoxicity. Brain Res. 1992;598(1–2):196–202. doi:10.1016/0006-8993(92)90183-A. DOI: 10.1016/0006-8993(92)90183-A
    • (1992) Brain Res , vol.598 , Issue.1-2 , pp. 196-202
    • Lei, S.Z.1    Zhang, D.2    Abele, A.E.3    Lipton, S.A.4
  • 50
    • 0026562113 scopus 로고
    • 2+]i in cultured rat hippocampal neurons following exposure to N-methyl-D-aspartate
    • PID: 1534370, COI: 1:CAS:528:DyaK38XhsVCnu7o%3D
    • 2+]i in cultured rat hippocampal neurons following exposure to N-methyl-D-aspartate. J Physiol. 1992;448:655–76.
    • (1992) J Physiol , vol.448 , pp. 655-676
    • Segal, M.1    Manor, D.2
  • 51
    • 0036190451 scopus 로고    scopus 로고
    • Effects of dantrolene on extracellular glutamate concentration and neuronal death in the rat hippocampal CA1 region subjected to transient ischemia
    • Nakayama R, Yano T, Ushijima K, Abe E, Terasaki H. Effects of dantrolene on extracellular glutamate concentration and neuronal death in the rat hippocampal CA1 region subjected to transient ischemia. Anesthesiology. 2002;96(3):705–10. doi:10.1097/00000542-200203000-00029. DOI: 10.1097/00000542-200203000-00029
    • (2002) Anesthesiology , vol.96 , Issue.3 , pp. 705-710
    • Nakayama, R.1    Yano, T.2    Ushijima, K.3    Abe, E.4    Terasaki, H.5
  • 52
    • 0030842946 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
    • Eliasson MJ, Sampei K, Mandir AS, et al. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med. 1997;3(10):1089–95. doi:10.1038/nm1097-1089. DOI: 10.1038/nm1097-1089
    • (1997) Nat Med , vol.3 , Issue.10 , pp. 1089-1095
    • Eliasson, M.J.1    Sampei, K.2    Mandir, A.S.3
  • 53
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, Snyder SH. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science. 1994;263(5147):687–9. doi:10.1126/science.8080500. DOI: 10.1126/science.8080500
    • (1994) Science , vol.263 , Issue.5147 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 54
    • 0031742987 scopus 로고    scopus 로고
    • Early postischemic dantrolene-induced amelioration of poly(ADP-ribose) polymerase-related bioenergetic failure in neonatal rat brain slices
    • Tasker RC, Sahota SK, Cotter FE, Williams SR. Early postischemic dantrolene-induced amelioration of poly(ADP-ribose) polymerase-related bioenergetic failure in neonatal rat brain slices. J Cereb Blood Flow Metab. 1998;18(12):1346–56. doi:10.1097/00004647-199812000-00009. DOI: 10.1097/00004647-199812000-00009
    • (1998) J Cereb Blood Flow Metab , vol.18 , Issue.12 , pp. 1346-1356
    • Tasker, R.C.1    Sahota, S.K.2    Cotter, F.E.3    Williams, S.R.4
  • 55
    • 34347344991 scopus 로고    scopus 로고
    • Sequential activation of poly(ADP-Ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis
    • Moubarak RS, Yuste VJ, Artus C, et al. Sequential activation of poly(ADP-Ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol. 2007;27(13):4844–62. doi:10.1128/MCB.02141-06. DOI: 10.1128/MCB.02141-06
    • (2007) Mol Cell Biol , vol.27 , Issue.13 , pp. 4844-4862
    • Moubarak, R.S.1    Yuste, V.J.2    Artus, C.3
  • 56
    • 0031398079 scopus 로고    scopus 로고
    • Thapsigargin induces apoptosis in SH-SY5Y neuroblastoma cells and cerebrocortical cultures
    • PID: 9315298, COI: 1:CAS:528:DyaK2sXnt12kt7w%3D
    • Nath R, Raser KJ, Hajimohammadreza I, Wang KK. Thapsigargin induces apoptosis in SH-SY5Y neuroblastoma cells and cerebrocortical cultures. Biochem Mol Biol Int. 1997;43(1):197–205.
    • (1997) Biochem Mol Biol Int , vol.43 , Issue.1 , pp. 197-205
    • Nath, R.1    Raser, K.J.2    Hajimohammadreza, I.3    Wang, K.K.4
  • 57
    • 0030917601 scopus 로고    scopus 로고
    • Alzheimer’s presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals
    • PID: 9151738, COI: 1:CAS:528:DyaK2sXjtl2msLk%3D
    • Guo Q, Sopher BL, Furukawa K, et al. Alzheimer’s presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. J Neurosci. 1997;17(11):4212–22.
    • (1997) J Neurosci , vol.17 , Issue.11 , pp. 4212-4222
    • Guo, Q.1    Sopher, B.L.2    Furukawa, K.3
  • 58
    • 0034051381 scopus 로고    scopus 로고
    • Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression
    • Wei H, Leeds P, Chen RW, et al. Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression. J Neurochem. 2000;75(1):81–90. doi:10.1046/j.1471-4159.2000.0750081.x. DOI: 10.1046/j.1471-4159.2000.0750081.x
    • (2000) J Neurochem , vol.75 , Issue.1 , pp. 81-90
    • Wei, H.1    Leeds, P.2    Chen, R.W.3
  • 59
    • 0037199911 scopus 로고    scopus 로고
    • Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression
    • Kim BC, Kim HT, Mamura M, Ambudkar IS, Choi KS, Kim SJ. Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression. J Biol Chem. 2002;277(35):31381–9. doi:10.1074/jbc.M203465200. DOI: 10.1074/jbc.M203465200
    • (2002) J Biol Chem , vol.277 , Issue.35 , pp. 31381-31389
    • Kim, B.C.1    Kim, H.T.2    Mamura, M.3    Ambudkar, I.S.4    Choi, K.S.5    Kim, S.J.6
  • 60
    • 0038024149 scopus 로고    scopus 로고
    • Dantrolene protects neurons against kainic acid induced apoptosis in vitro and in vivo
    • Popescu BO, Oprica M, Sajin M, et al. Dantrolene protects neurons against kainic acid induced apoptosis in vitro and in vivo. J Cell Mol Med. 2002;6(4):555–69. doi:10.1111/j.1582-4934.2002.tb00454.x. DOI: 10.1111/j.1582-4934.2002.tb00454.x
    • (2002) J Cell Mol Med , vol.6 , Issue.4 , pp. 555-569
    • Popescu, B.O.1    Oprica, M.2    Sajin, M.3
  • 61
    • 37549021122 scopus 로고    scopus 로고
    • The effects of dantrolene on hypoxic-ischemic injury in the neonatal rat brain
    • PID: 18165582, COI: 1:CAS:528:DC%2BD2sXhsVOisLbO, Table of contents
    • Gwak M, Park P, Kim K, et al. The effects of dantrolene on hypoxic-ischemic injury in the neonatal rat brain. Anesth Analg. 2008;106(1):227–33. Table of contents.
    • (2008) Anesth Analg , vol.106 , Issue.1 , pp. 227-233
    • Gwak, M.1    Park, P.2    Kim, K.3
  • 62
    • 0038177515 scopus 로고    scopus 로고
    • Molecular signaling in death receptor and mitochondrial pathways of apoptosis
    • PID: 12469180, COI: 1:CAS:528:DC%2BD3sXhsVSgsw%3D%3D, Review
    • Gupta S. Molecular signaling in death receptor and mitochondrial pathways of apoptosis. Int J Oncol. 2003;22(1):15–20. Review.
    • (2003) Int J Oncol , vol.22 , Issue.1 , pp. 15-20
    • Gupta, S.1
  • 63
    • 24844442696 scopus 로고    scopus 로고
    • Intracellular calcium release induced by caffeine is buffered by mitochondria in superior cervical ganglion cells
    • Bucholz J, Tsai H, Duckles SP. Intracellular calcium release induced by caffeine is buffered by mitochondria in superior cervical ganglion cells. FASEB J. 1996;10:A 142.
    • (1996) FASEB J. , vol.10
    • Bucholz, J.1    Tsai, H.2    Duckles, S.P.3
  • 64
    • 0028983614 scopus 로고
    • 2+ and 5-aminolevulinic acid-derived oxyradicals promote injury to isolated mitochondria?
    • 2+ and 5-aminolevulinic acid-derived oxyradicals promote injury to isolated mitochondria? Free Radic Biol Med. 1995;19(3):381–90. doi:10.1016/0891-5849(95)00015-P. DOI: 10.1016/0891-5849(95)00015-P
    • (1995) Free Radic Biol Med , vol.19 , Issue.3 , pp. 381-390
    • Hermes-Lima, M.1
  • 65
    • 33846641318 scopus 로고    scopus 로고
    • Matrix regulation of skeletal cell apoptosis III: mechanism of ion pair-induced apoptosis
    • PID: 17006955, COI: 1:CAS:528:DC%2BD2sXht1Sksrw%3D
    • Saunders R, Szymczyk KH, Shapiro IM, Adams CS. Matrix regulation of skeletal cell apoptosis III: mechanism of ion pair-induced apoptosis. J Cell Biochem. 2007;100(3):703–15. DOI: 10.1002/jcb.21001
    • (2007) J Cell Biochem , vol.100 , Issue.3 , pp. 703-715
    • Saunders, R.1    Szymczyk, K.H.2    Shapiro, I.M.3    Adams, C.S.4
  • 66
    • 0028116119 scopus 로고
    • Possible mechanism of dantrolene stabilization of cultured neuroblastoma cell plasma membranes
    • PID: 7931341, COI: 1:CAS:528:DyaK2cXmslWqtbs%3D
    • Hayashi T, Kagaya A, Motohashi N, Yamawaki S. Possible mechanism of dantrolene stabilization of cultured neuroblastoma cell plasma membranes. J Neurochem. 1994;63(5):1849–54. DOI: 10.1046/j.1471-4159.1994.63051849.x
    • (1994) J Neurochem , vol.63 , Issue.5 , pp. 1849-1854
    • Hayashi, T.1    Kagaya, A.2    Motohashi, N.3    Yamawaki, S.4
  • 67
    • 0023280082 scopus 로고
    • Compound 48/80 is a potent inhibitor of phospholipase C and a dual modulator of phospholipase A2 from human platelet
    • PID: 3607084, COI: 1:CAS:528:DyaL2sXlvFSlsrY%3D
    • Bronner C, Wiggins C, Monte D, et al. Compound 48/80 is a potent inhibitor of phospholipase C and a dual modulator of phospholipase A2 from human platelet. Biochim Biophys Acta. 1987;920(3):301–5.
    • (1987) Biochim Biophys Acta , vol.920 , Issue.3 , pp. 301-305
    • Bronner, C.1    Wiggins, C.2    Monte, D.3
  • 68
    • 20444390622 scopus 로고    scopus 로고
    • The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers
    • Li F, Hayashi T, Jin G, et al. The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers. Brain Res. 2005;1048(1–2):59–68. doi:10.1016/j.brainres.2005.04.058. DOI: 10.1016/j.brainres.2005.04.058
    • (2005) Brain Res , vol.1048 , Issue.1-2 , pp. 59-68
    • Li, F.1    Hayashi, T.2    Jin, G.3
  • 69
    • 0035960074 scopus 로고    scopus 로고
    • Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum
    • Xu K, Tavernarakis N, Driscoll M. Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum. Neuron. 2001;31(6):957–71. doi:10.1016/S0896-6273(01)00432-9.
    • (2001) Neuron , vol.31 , Issue.6 , pp. 957
    • Xu, K.1    Tavernarakis, N.2    Driscoll, M.3
  • 70
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • Guo Q, Fu W, Sopher BL, et al. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med. 1999;5(1):101–6. doi:10.1038/4789. DOI: 10.1038/4789
    • (1999) Nat Med , vol.5 , Issue.1 , pp. 101-106
    • Guo, Q.1    Fu, W.2    Sopher, B.L.3
  • 71
    • 0034652369 scopus 로고    scopus 로고
    • Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis
    • PID: 10662826, COI: 1:CAS:528:DC%2BD3cXitVOktbs%3D
    • Mattson MP, Zhu H, Yu J, Kindy MS. Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis. J Neurosci. 2000;20(4):1358–64.
    • (2000) J Neurosci , vol.20 , Issue.4 , pp. 1358-1364
    • Mattson, M.P.1    Zhu, H.2    Yu, J.3    Kindy, M.S.4
  • 72
    • 0035087360 scopus 로고    scopus 로고
    • A3 adenosine receptor stimulation modulates sarcoplasmic reticulum Ca(2+) release in rat heart
    • Zucchi R, Yu G, Ghelardoni S, Ronca F, Ronca-Testoni S. A3 adenosine receptor stimulation modulates sarcoplasmic reticulum Ca(2+) release in rat heart. Cardiovasc Res. 2001;50(1):56–64. doi:10.1016/S0008-6363(00)00318-7. DOI: 10.1016/S0008-6363(00)00318-7
    • (2001) Cardiovasc Res , vol.50 , Issue.1 , pp. 56-64
    • Zucchi, R.1    Yu, G.2    Ghelardoni, S.3    Ronca, F.4    Ronca-Testoni, S.5
  • 73
    • 0034013661 scopus 로고    scopus 로고
    • Protection of ischemic rat heart by dantrolene, an antagonist of the sarcoplasmic reticulum calcium release channel
    • Yu G, Zucchi R, Ronca-Testoni S, Ronca G. Protection of ischemic rat heart by dantrolene, an antagonist of the sarcoplasmic reticulum calcium release channel. Basic Res Cardiol. 2000;95(2):137–43. doi:10.1007/s003950050175. DOI: 10.1007/s003950050175
    • (2000) Basic Res Cardiol , vol.95 , Issue.2 , pp. 137-143
    • Yu, G.1    Zucchi, R.2    Ronca-Testoni, S.3    Ronca, G.4
  • 74
    • 34247635620 scopus 로고    scopus 로고
    • Ryanodine receptor antagonism protects the ischemic liver and modulates TNF-alpha and IL-10
    • Lopez-Neblina F, Toledo-Pereyra LH, Toledo AH, Walsh J. Ryanodine receptor antagonism protects the ischemic liver and modulates TNF-alpha and IL-10. J Surg Res. 2007;140(1):121–8. doi:10.1016/j.jss.2006.12.003. DOI: 10.1016/j.jss.2006.12.003
    • (2007) J Surg Res , vol.140 , Issue.1 , pp. 121-128
    • Lopez-Neblina, F.1    Toledo-Pereyra, L.H.2    Toledo, A.H.3    Walsh, J.4
  • 76
    • 0027500398 scopus 로고
    • No dantrolene protection in a dog model of complete cerebral ischaemia
    • PID: 8098851, COI: 1:CAS:528:DyaK3sXkt1Sgs7g%3D
    • Kross J, Fleischer JE, Milde JH, Gronert GA. No dantrolene protection in a dog model of complete cerebral ischaemia. Neurol Res. 1993;15(1):37–40.
    • (1993) Neurol Res , vol.15 , Issue.1 , pp. 37-40
    • Kross, J.1    Fleischer, J.E.2    Milde, J.H.3    Gronert, G.A.4
  • 77
    • 4644237411 scopus 로고    scopus 로고
    • Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures
    • Martinez-Sanchez M, Striggow F, Schroder UH, Kahlert S, Reymann KG, Reiser G. Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures. Neuroscience. 2004;128(4):729–40. doi:10.1016/j.neuroscience.2004.06.074. DOI: 10.1016/j.neuroscience.2004.06.074
    • (2004) Neuroscience , vol.128 , Issue.4 , pp. 729-740
    • Martinez-Sanchez, M.1    Striggow, F.2    Schroder, U.H.3    Kahlert, S.4    Reymann, K.G.5    Reiser, G.6
  • 78
    • 85008246634 scopus 로고    scopus 로고
    • Comparison of the cerebral protective effects of thiopental, propofol and dantrolene on focal cerebral ischemia induced by temporary middle cerebral artery occlusion in the rat under the monitoring of compressed spectral array
    • Kim JH, Kim SH, Min KTM, Kim MH, Song SK, Lee BH. Comparison of the cerebral protective effects of thiopental, propofol and dantrolene on focal cerebral ischemia induced by temporary middle cerebral artery occlusion in the rat under the monitoring of compressed spectral array. J Korean Neurosurg Soc. 2002;32:239–45.
    • (2002) J Korean Neurosurg Soc , vol.32 , pp. 239-245
    • Kim, J.H.1    Kim, S.H.2    Min, K.T.M.3    Kim, M.H.4    Song, S.K.5    Lee, B.H.6
  • 79
    • 0027339535 scopus 로고
    • 2+ elevation induced by in vitro ischemia-like condition in hippocampal slices
    • 2+ elevation induced by in vitro ischemia-like condition in hippocampal slices. Brain Res. 1993;601(1–2):103–10. doi:10.1016/0006-8993(93)91700-3. DOI: 10.1016/0006-8993(93)91700-3
    • (1993) Brain Res , vol.601 , Issue.1-2 , pp. 103-110
    • Mitani, A.1    Yanase, H.2    Sakai, K.3    Wake, Y.4    Kataoka, K.5
  • 80
    • 0036169993 scopus 로고    scopus 로고
    • Role of intracellular calcium stores in cell death from oxygen-glucose deprivation in a neuronal cell line
    • Wang C, Nguyen HN, Maguire JL, Perry DC. Role of intracellular calcium stores in cell death from oxygen-glucose deprivation in a neuronal cell line. J Cereb Blood Flow Metab. 2002;22(2):206–14. doi:10.1097/00004647-200202000-00008. DOI: 10.1097/00004647-200202000-00008
    • (2002) J Cereb Blood Flow Metab , vol.22 , Issue.2 , pp. 206-214
    • Wang, C.1    Nguyen, H.N.2    Maguire, J.L.3    Perry, D.C.4
  • 81
    • 0027202580 scopus 로고
    • Dantrolene protects against ischemic, delayed neuronal death in gerbil brain
    • Zhang L, Andou Y, Masuda S, Mitani A, Kataoka K. Dantrolene protects against ischemic, delayed neuronal death in gerbil brain. Neurosci Lett. 1993;158(1):105–8. doi:10.1016/0304-3940(93)90623-S. DOI: 10.1016/0304-3940(93)90623-S
    • (1993) Neurosci Lett , vol.158 , Issue.1 , pp. 105-108
    • Zhang, L.1    Andou, Y.2    Masuda, S.3    Mitani, A.4    Kataoka, K.5
  • 82
    • 0032782594 scopus 로고    scopus 로고
    • Neuroprotective effects of early vs. late administration of dantrolene in experimental status epilepticus
    • Niebauer M, Gruenthal M. Neuroprotective effects of early vs. late administration of dantrolene in experimental status epilepticus. Neuropharmacology. 1999;38(9):1343–8. doi:10.1016/S0028-3908(99)00059-3. DOI: 10.1016/S0028-3908(99)00059-3
    • (1999) Neuropharmacology , vol.38 , Issue.9 , pp. 1343-1348
    • Niebauer, M.1    Gruenthal, M.2
  • 83
    • 0034949296 scopus 로고    scopus 로고
    • The effects of dantrolene alone or in combination with nimodipine in glutamate-induced neurotoxicity in cerebellar granular cell cultures of rat pups
    • GepdIremen A, Duzenl IS, Hacimuftuoglu A, Suleyman H, Oztas S. The effects of dantrolene alone or in combination with nimodipine in glutamate-induced neurotoxicity in cerebellar granular cell cultures of rat pups. Pharmacol Res. 2001;43(3):241–4. doi:10.1006/phrs.2000.0770. DOI: 10.1006/phrs.2000.0770
    • (2001) Pharmacol Res , vol.43 , Issue.3 , pp. 241-244
    • GepdIremen, A.1    Duzenl, I.S.2    Hacimuftuoglu, A.3    Suleyman, H.4    Oztas, S.5
  • 84
    • 0027432951 scopus 로고
    • Intracerebral 1S, 3R–1-aminocyclopentane-1, 3-dicarboxylic acid (1S, 3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists
    • Tizzano JP, Griffey KI, Johnson JA, Fix AS, Helton DR, Schoepp DD. Intracerebral 1S, 3R–1-aminocyclopentane-1, 3-dicarboxylic acid (1S, 3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists. Neurosci Lett. 1993;162(1–2):12–6. doi:10.1016/0304-3940(93)90548-Y. DOI: 10.1016/0304-3940(93)90548-Y
    • (1993) Neurosci Lett , vol.162 , Issue.1-2 , pp. 12-16
    • Tizzano, J.P.1    Griffey, K.I.2    Johnson, J.A.3    Fix, A.S.4    Helton, D.R.5    Schoepp, D.D.6
  • 85
    • 0030946425 scopus 로고    scopus 로고
    • Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice
    • Borowicz KK, Gasior M, Kleinrok Z, Czuczwar SJ. Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice. Eur J Pharmacol. 1997;323(1):45–51. doi:10.1016/S0014-2999(97)00020-4. DOI: 10.1016/S0014-2999(97)00020-4
    • (1997) Eur J Pharmacol , vol.323 , Issue.1 , pp. 45-51
    • Borowicz, K.K.1    Gasior, M.2    Kleinrok, Z.3    Czuczwar, S.J.4
  • 86
    • 0024473748 scopus 로고
    • Whole-body autoradiography of 14C-dantrolene in the marmoset monkey
    • PID: 2502774, COI: 1:CAS:528:DyaL1MXht1yjsLc%3D
    • Wuis EW, Rijntjes NV, van der Kleijn E. Whole-body autoradiography of 14C-dantrolene in the marmoset monkey. Pharmacol Toxicol. 1989;64(1):156–8. DOI: 10.1111/j.1600-0773.1989.tb00621.x
    • (1989) Pharmacol Toxicol , vol.64 , Issue.1 , pp. 156-158
    • Wuis, E.W.1    Rijntjes, N.V.2    van der Kleijn, E.3
  • 87
    • 44149086662 scopus 로고    scopus 로고
    • Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds
    • Enokizono J, Kusuhara H, Ose A, Schinkel AH, Sugiyama Y. Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds. Drug Metab Dispos. 2008;36(6):995–1002. doi:10.1124/dmd.107.019257. DOI: 10.1124/dmd.107.019257
    • (2008) Drug Metab Dispos , vol.36 , Issue.6 , pp. 995-1002
    • Enokizono, J.1    Kusuhara, H.2    Ose, A.3    Schinkel, A.H.4    Sugiyama, Y.5
  • 88
    • 39749132196 scopus 로고    scopus 로고
    • Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine
    • PID: 18292687
    • Bostrom E, Hammarlund-Udenaes M, Simonsson US. Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine. Anesthesiology. 2008;108(3):495–505.
    • (2008) Anesthesiology , vol.108 , Issue.3 , pp. 495-505
    • Bostrom, E.1    Hammarlund-Udenaes, M.2    Simonsson, U.S.3
  • 89
    • 0019417287 scopus 로고
    • The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration
    • PID: 7241161, COI: 1:STN:280:DyaL3M3hslGjsQ%3D%3D
    • Meyler WJ, Bakker H, Kok JJ, Agoston S, Wesseling H. The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration. J Neurol Neurosurg Psychiatry. 1981;44(4):334–9. DOI: 10.1136/jnnp.44.4.334
    • (1981) J Neurol Neurosurg Psychiatry , vol.44 , Issue.4 , pp. 334-339
    • Meyler, W.J.1    Bakker, H.2    Kok, J.J.3    Agoston, S.4    Wesseling, H.5
  • 90
    • 0027398745 scopus 로고
    • Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study
    • Nisijima K, Ishiguro T. Does dantrolene influence central dopamine and serotonin metabolism in the neuroleptic malignant syndrome? A retrospective study. Biol Psychiatry. 1993;33(1):45–8. doi:10.1016/0006-3223(93)90277-K. DOI: 10.1016/0006-3223(93)90277-K
    • (1993) Biol Psychiatry , vol.33 , Issue.1 , pp. 45-48
    • Nisijima, K.1    Ishiguro, T.2
  • 91
    • 34547795720 scopus 로고    scopus 로고
    • NXY-059 for the treatment of acute ischemic stroke
    • Shuaib A, Lees KR, Lyden P, et al. NXY-059 for the treatment of acute ischemic stroke. N Engl J Med. 2007;357(6):562–71. doi:10.1056/NEJMoa070240. DOI: 10.1056/NEJMoa070240
    • (2007) N Engl J Med , vol.357 , Issue.6 , pp. 562-571
    • Shuaib, A.1    Lees, K.R.2    Lyden, P.3
  • 92
    • 39749191084 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Rosamond W, Flegal K, Furie K, et al. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2008;117(4):e25–146. doi:10.1161/CIRCULATIONAHA.107.187998. DOI: 10.1161/CIRCULATIONAHA.107.187998
    • (2008) Circulation , vol.117 , Issue.4 , pp. e25-e146
    • Rosamond, W.1    Flegal, K.2    Furie, K.3
  • 93
    • 0022990535 scopus 로고
    • Physiological and ultrastructural studies on the mechanism of stretch-induced contractile activation in rabbit cerebral artery smooth muscle
    • Nakayama K, Suzuki S, Sugi H. Physiological and ultrastructural studies on the mechanism of stretch-induced contractile activation in rabbit cerebral artery smooth muscle. Jpn J Physiol. 1986;36(4):745–60. doi:10.2170/jjphysiol.36.745. DOI: 10.2170/jjphysiol.36.745
    • (1986) Jpn J Physiol , vol.36 , Issue.4 , pp. 745-760
    • Nakayama, K.1    Suzuki, S.2    Sugi, H.3
  • 94
    • 70349588761 scopus 로고    scopus 로고
    • Dantrolene inhibits serotonin and endothelin-1 vasoconstriction in the rat basilar artery
    • Sims JR, Salomone S. Dantrolene inhibits serotonin and endothelin-1 vasoconstriction in the rat basilar artery. Neurocritical care. 2007;6(3):267 A107.
    • (2007) Neurocritical care , vol.6 , Issue.3 , pp. 267
    • Sims, J.R.1    Salomone, S.2
  • 95
  • 96
    • 33846925575 scopus 로고    scopus 로고
    • Narrative review: reversible cerebral vasoconstriction syndromes
    • PID: 17200220
    • Calabrese LH, Dodick DW, Schwedt TJ, Singhal AB. Narrative review: reversible cerebral vasoconstriction syndromes. Ann Intern Med. 2007;146(1):34–44.
    • (2007) Ann Intern Med , vol.146 , Issue.1 , pp. 34-44
    • Calabrese, L.H.1    Dodick, D.W.2    Schwedt, T.J.3    Singhal, A.B.4
  • 97
    • 0026728590 scopus 로고
    • The importance of brain temperature in cerebral injury
    • PID: 1613807
    • Dietrich WD. The importance of brain temperature in cerebral injury. J Neurotrauma. 1992;9(Suppl 2):S475–85.
    • (1992) J Neurotrauma , vol.9 , pp. S475-S485
    • Dietrich, W.D.1
  • 98
    • 0028879709 scopus 로고
    • Fever in acute stroke worsens prognosis. A prospective study
    • PID: 7482646, COI: 1:STN:280:DyaK28%2FktlKktQ%3D%3D
    • Azzimondi G, Bassein L, Nonino F, et al. Fever in acute stroke worsens prognosis. A prospective study. Stroke. 1995;26(11):2040–3.
    • (1995) Stroke , vol.26 , Issue.11 , pp. 2040-2043
    • Azzimondi, G.1    Bassein, L.2    Nonino, F.3
  • 99
    • 0030039285 scopus 로고    scopus 로고
    • Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome
    • Reith J, Jorgensen HS, Pedersen PM, et al. Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome. Lancet. 1996;347(8999):422–5. doi:10.1016/S0140-6736(96)90008-2. DOI: 10.1016/S0140-6736(96)90008-2
    • (1996) Lancet , vol.347 , Issue.8999 , pp. 422-425
    • Reith, J.1    Jorgensen, H.S.2    Pedersen, P.M.3
  • 100
    • 0031885950 scopus 로고    scopus 로고
    • Combating hyperthermia in acute stroke: a significant clinical concern
    • PID: 9472901, COI: 1:STN:280:DyaK1c7jt1ansQ%3D%3D
    • Ginsberg MD, Busto R. Combating hyperthermia in acute stroke: a significant clinical concern. Stroke. 1998;29(2):529–34.
    • (1998) Stroke , vol.29 , Issue.2 , pp. 529-534
    • Ginsberg, M.D.1    Busto, R.2
  • 101
    • 34147124516 scopus 로고    scopus 로고
    • Fever after subarachnoid hemorrhage. Risk factors and impact on outcome
    • PID: 17314332, COI: 1:STN:280:DC%2BD2s7os1Ogtw%3D%3D
    • Fernandez A, Schmidt JM, Claassen J, et al. Fever after subarachnoid hemorrhage. Risk factors and impact on outcome. Neurology. 2007;68:1013–1019. DOI: 10.1212/01.wnl.0000258543.45879.f5
    • (2007) Neurology , vol.68 , pp. 1013-1019
    • Fernandez, A.1    Schmidt, J.M.2    Claassen, J.3
  • 102
    • 33644610186 scopus 로고    scopus 로고
    • Impact of medical complications on outcome after subarachnoid hemorrhage
    • PID: 16521258, Quiz 24
    • Wartenberg KE, Schmidt JM, Claassen J, et al. Impact of medical complications on outcome after subarachnoid hemorrhage. Crit Care Med. 2006;34(3):617–23. Quiz 24.
    • (2006) Crit Care Med , vol.34 , Issue.3 , pp. 617-623
    • Wartenberg, K.E.1    Schmidt, J.M.2    Claassen, J.3
  • 103
    • 0028278894 scopus 로고
    • Rate and gender dependence of the sweating, vasoconstriction, and shivering thresholds in humans
    • Lopez M, Sessler DI, Walter K, Emerick T, Ozaki M. Rate and gender dependence of the sweating, vasoconstriction, and shivering thresholds in humans. Anesthesiology. 1994;80(4):780–8. doi:10.1097/00000542-199404000-00009. DOI: 10.1097/00000542-199404000-00009
    • (1994) Anesthesiology , vol.80 , Issue.4 , pp. 780-788
    • Lopez, M.1    Sessler, D.I.2    Walter, K.3    Emerick, T.4    Ozaki, M.5
  • 104
    • 0023785909 scopus 로고
    • The effects of shivering on oxygen consumption and carbon dioxide production in patients rewarming from hypothermic cardiopulmonary bypass
    • PID: 3135952, COI: 1:STN:280:DyaL1c3psFegsg%3D%3D
    • Ralley FE, Wynands JE, Ramsay JG, Carli F, MacSullivan R. The effects of shivering on oxygen consumption and carbon dioxide production in patients rewarming from hypothermic cardiopulmonary bypass. Can J Anaesth. 1988;35(4):332–7.
    • (1988) Can J Anaesth , vol.35 , Issue.4 , pp. 332-337
    • Ralley, F.E.1    Wynands, J.E.2    Ramsay, J.G.3    Carli, F.4    MacSullivan, R.5
  • 106
    • 0025164574 scopus 로고
    • Pro- and anticonvulsant effects of anesthetics (Part II)
    • Modica PA, Tempelhoff R, White PF. Pro- and anticonvulsant effects of anesthetics (Part II). Anesth Analg. 1990;70(4):433–44. doi:10.1213/00000539-199004000-00016. DOI: 10.1213/00000539-199004000-00016
    • (1990) Anesth Analg , vol.70 , Issue.4 , pp. 433-444
    • Modica, P.A.1    Tempelhoff, R.2    White, P.F.3
  • 107
    • 0030802483 scopus 로고    scopus 로고
    • Clonidine at induction reduces shivering after general anaesthesia
    • PID: 9067044, COI: 1:STN:280:DyaK2s3hvFOlsg%3D%3D
    • Buggy D, Higgins P, Moran C, O’Donovan F, McCarroll M. Clonidine at induction reduces shivering after general anaesthesia. Can J Anaesth. 1997;44(3):263–7.
    • (1997) Can J Anaesth , vol.44 , Issue.3 , pp. 263-267
    • Buggy, D.1    Higgins, P.2    Moran, C.3    O’Donovan, F.4    McCarroll, M.5
  • 108
    • 31344452422 scopus 로고    scopus 로고
    • Dexmedetomidine and meperidine prevent postanaesthetic shivering
    • Bicer C, Esmaoglu A, Akin A, Boyaci A. Dexmedetomidine and meperidine prevent postanaesthetic shivering. Eur J Anaesthesiol. 2006;23(2):149–53. doi:10.1017/S0265021505002061. DOI: 10.1017/S0265021505002061
    • (2006) Eur J Anaesthesiol , vol.23 , Issue.2 , pp. 149-153
    • Bicer, C.1    Esmaoglu, A.2    Akin, A.3    Boyaci, A.4
  • 109
    • 0028952096 scopus 로고
    • HIV-1 coat protein gp120-induced increases in levels of intrasynaptosomal calcium
    • Nath A, Padua RA, Geiger JD. HIV-1 coat protein gp120-induced increases in levels of intrasynaptosomal calcium. Brain Res. 1995;678(1–2):200–6. doi:10.1016/0006-8993(95)00185-S. DOI: 10.1016/0006-8993(95)00185-S
    • (1995) Brain Res , vol.678 , Issue.1-2 , pp. 200-206
    • Nath, A.1    Padua, R.A.2    Geiger, J.D.3
  • 110
    • 0028913489 scopus 로고
    • Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis
    • Berg M, Bruhn T, Frandsen A, Schousboe A, Diemer NH. Kainic acid-induced seizures and brain damage in the rat: role of calcium homeostasis. J Neurosci Res. 1995;40(5):641–6. doi:10.1002/jnr.490400509. DOI: 10.1002/jnr.490400509
    • (1995) J Neurosci Res , vol.40 , Issue.5 , pp. 641-646
    • Berg, M.1    Bruhn, T.2    Frandsen, A.3    Schousboe, A.4    Diemer, N.H.5
  • 111
    • 0035847254 scopus 로고    scopus 로고
    • Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice
    • Nagatomo I, Hashiguchi W, Tominaga M, Akasaki Y, Uchida M, Takigawa M. Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice. Brain Res. 2001;888(2):306–10. doi:10.1016/S0006-8993(00)03101-2. DOI: 10.1016/S0006-8993(00)03101-2
    • (2001) Brain Res , vol.888 , Issue.2 , pp. 306-310
    • Nagatomo, I.1    Hashiguchi, W.2    Tominaga, M.3    Akasaki, Y.4    Uchida, M.5    Takigawa, M.6
  • 112
    • 0031606341 scopus 로고    scopus 로고
    • 2+ rise induced by oxygen/glucose deprivation in cortical neurons
    • PID: 9445351, COI: 1:CAS:528:DyaK1cXntVKqtA%3D%3D, Discussion 2
    • 2+ rise induced by oxygen/glucose deprivation in cortical neurons. Stroke. 1998;29(1):196–201. Discussion 2.
    • (1998) Stroke , vol.29 , Issue.1 , pp. 196-201
    • Pisani, A.1    Calabresi, P.2    Tozzi, A.3    D’Angelo, V.4    Bernardi, G.5
  • 113
    • 0037032669 scopus 로고    scopus 로고
    • Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex
    • Phillis JW, Diaz FG, O’Regan MH, Pilitsis JG. Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex. Brain Res. 2002;957(1):12–24. doi:10.1016/S0006-8993(02)03578-3. DOI: 10.1016/S0006-8993(02)03578-3
    • (2002) Brain Res , vol.957 , Issue.1 , pp. 12-24
    • Phillis, J.W.1    Diaz, F.G.2    O’Regan, M.H.3    Pilitsis, J.G.4
  • 114
    • 0034910966 scopus 로고    scopus 로고
    • Dantrolene ameliorates delayed cell death and concomitant DNA fragmentation in the rat hippocampal CA1 neurons subjected to mild ischemia
    • Yano T, Nakayama R, Imaizumi T, Terasaki H, Ushijima K. Dantrolene ameliorates delayed cell death and concomitant DNA fragmentation in the rat hippocampal CA1 neurons subjected to mild ischemia. Resuscitation. 2001;50(1):117–25. doi:10.1016/S0300-9572(00)00369-5. DOI: 10.1016/S0300-9572(00)00369-5
    • (2001) Resuscitation , vol.50 , Issue.1 , pp. 117-125
    • Yano, T.1    Nakayama, R.2    Imaizumi, T.3    Terasaki, H.4    Ushijima, K.5
  • 115
    • 0030028634 scopus 로고    scopus 로고
    • Trauma-induced neurotoxicity in rat hippocampal neurons
    • PID: 8553387, COI: 1:STN:280:DyaK287js1amtQ%3D%3D
    • Yoon KW, Mitchell HL, Broder LD, Brooker RW, Delisle RK. Trauma-induced neurotoxicity in rat hippocampal neurons. Stroke. 1996;27(1):122–6.
    • (1996) Stroke , vol.27 , Issue.1 , pp. 122-126
    • Yoon, K.W.1    Mitchell, H.L.2    Broder, L.D.3    Brooker, R.W.4    Delisle, R.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.