STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

Nature Cell Biology

Volumn 8, Issue 9, 2006, Pages 1003-1010

  Huang, Guo N ^a   Zeng, Weizhong ^b   Kim, Joo Young ^b   Yuan, Joseph P ^b   Han, Linhuang ^a   Muallem, Shmuel ^b   Worley, Paul F ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; MEMBRANE PROTEIN; RECEPTOR; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL MEMBRANE TRANSPORT; CELL SECRETION; CELL STRAIN HEK293; CHANNEL GATING; ENDOPLASMIC RETICULUM; GENE DELETION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MUTANT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR BINDING; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL LINE; CELL NUCLEUS; HUMANS; ION CHANNEL GATING; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT; TRPC CATION CHANNELS;

EID: 33748136477     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1454     Document Type: Article

References (19)

1. Parekh, A. B. & Putney, J. W., Jr. Store-operated calcium channels. Physiol. Rev. 85, 757-810 (2005).
2. Berridge, M. J., Bootman, M. D. & Roderick, H. L. Calcium signalling: dynamics, homeostasis and remodelling. Nature Rev. Mol. Cell Biol. 4, 517-529 (2003).
3. 2+ channels. Proc. Natl Acad. Sci. USA 103, 4040-4045 (2006).
4. 2+ store to the plasma membrane. Nature 437, 902-905 (2005).
5. 2+ channel function. J. Cell Biol. 169, 435-445 (2005).
6. 2+ influx. Curr. Biol. 15, 1235-1241 (2005).
7. Feske, S. et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441, 179-186 (2006).
8. 2+ entry. Science 312, 1220-1223 (2006).
9. Williams, R. T. et al. Identification and characterization of the STIM (stromal interaction molecule) gene family: Coding for a novel class of transmembrane proteins. Biochem. J. 357, 673-685 (2001).
10. Crabtree, G. R. & Olson, E. N. NFAT signaling: Choreographing the social lives of cells. Cell 109 (Suppl.), S67-S79 (2002).
11. Freichel, M. et al. Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies. J. Physiol. 567, 59-66 (2005).
12. 2+-sensitive cation channels. J. Biol. Chem. 275, 27799-27805 (2000).
13. Northrop, J. P., Ullman, K. S. & Crabtree, G. R. Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NFAT) complex. J. Biol. Chem. 268, 2917-2923 (1993).
14. Northrop, J. P. et al. NFAT components define a family of transcription factors targeted in T-cell activation. Nature 369, 497-502 (1994).
15. Tsai, R. Y. & Reed, R. R. Using a eukaryotic GST fusion vector for proteins difficult to express in E. coli. Biotechniques 23, 794-796, 798, 800 (1997).
16. Sun, L. et al. Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes. Immunity 8, 703-711 (1998).
17. Yuan, J. P. et al. Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell 114, 777-789 (2003).
18. Xiao, B. et al. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron 21, 707-716 (1998).
19. Kozak, J. A., Kerschbaum, H. H. & Cahalan, M. D. Distinct properties of CRAC and MIC channels in RBL cells. J. Gen. Physiol. 120, 221-235 (2002).