-
1
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
PMID:13332224
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956; 11:298-300; PMID:13332224.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
2
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
PMID:15734681
-
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005; 120:483-95; PMID:15734681; http://dx.doi.org/10.1016/j.cell.2005.02.001.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
3
-
-
0031916984
-
The free radical theory of aging matures
-
PMID:9562038
-
Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev 1998; 78:547-81; PMID:9562038.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
4
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
PMID:21746850
-
Finkel T. Signal transduction by reactive oxygen species. J Cell Biol 2011; 194:7-15; PMID:21746850; http://dx.doi.org/10.1083/jcb.201102095.
-
(2011)
J Cell Biol
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
5
-
-
84985570313
-
Biochemistry of Oxidative Stress
-
Sies H. Biochemistry of Oxidative Stress. Angew Chem Int Ed Engl 1986; 25:1058-71; http://dx.doi.org/10.1002/anie.198610581.
-
(1986)
Angew Chem Int Ed Engl
, vol.25
, pp. 1058-1071
-
-
Sies, H.1
-
6
-
-
0030894162
-
Oxidative stress: Oxidants and antioxidants
-
PMID:9129943
-
Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol 1997; 82:291-5; PMID:9129943.
-
(1997)
Exp Physiol
, vol.82
, pp. 291-295
-
-
Sies, H.1
-
7
-
-
67649840689
-
Regulation of superoxide dismutase genes: Implications in disease
-
PMID:19477268
-
Miao L, St Clair DK. Regulation of superoxide dismutase genes: implications in disease. Free Radic Biol Med 2009; 47:344-56; PMID:19477268; http://dx.doi.org/10.1016/j.freeradbiomed.2009.05.018.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 344-356
-
-
Miao, L.1
St Clair, D.K.2
-
8
-
-
34147210988
-
Hydrogen peroxide sensing and signaling
-
PMID:17434122
-
Veal EA, Day AM, Morgan BA. Hydrogen peroxide sensing and signaling. Mol Cell 2007; 26:1-14; PMID:17434122; http://dx.doi.org/10.1016/j.molcel.2007.03. 016.
-
(2007)
Mol Cell
, vol.26
, pp. 1-14
-
-
Veal, E.A.1
Day, A.M.2
Morgan, B.A.3
-
9
-
-
0037157824
-
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
-
PMID:12119354
-
Werner E, Werb Z. Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. J Cell Biol 2002; 158:357-68; PMID:12119354; http://dx.doi.org/10.1083/jcb.200111028.
-
(2002)
J Cell Biol
, vol.158
, pp. 357-368
-
-
Werner, E.1
Werb, Z.2
-
10
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
PMID:15879174
-
Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 2005; 308:1909-11; PMID:15879174; http://dx.doi.org/10. 1126/science.1106653.
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
-
11
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
PMID:12239572
-
Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 2002; 419:316-21; PMID:12239572; http://dx.doi.org/10.1038/ nature01036.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
-
12
-
-
11144331539
-
Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study
-
PMID:15621215
-
Stessman J, Maaravi Y, Hammerman-Rozenberg R, Cohen A, Nemanov L, Gritsenko I, et al. Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study. Mech Ageing Dev 2005; 126:333-9; PMID:15621215; http://dx.doi.org/10.1016/j.mad.2004.08.025.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 333-339
-
-
Stessman, J.1
Maaravi, Y.2
Hammerman-Rozenberg, R.3
Cohen, A.4
Nemanov, L.5
Gritsenko, I.6
-
13
-
-
19944401844
-
The mitochondrial superoxide dismutase A16V polymorphism in the cardiomyopathy associated with hereditary haemochromatosis
-
PMID:15591282
-
Valenti L, Conte D, Piperno A, Dongiovanni P, Fracanzani AL, Fraquelli M, et al. The mitochondrial superoxide dismutase A16V polymorphism in the cardiomyopathy associated with hereditary haemochromatosis. J Med Genet 2004; 41:946-50; PMID:15591282; http://dx.doi.org/10.1136/jmg.2004.019588.
-
(2004)
J Med Genet
, vol.41
, pp. 946-950
-
-
Valenti, L.1
Conte, D.2
Piperno, A.3
Dongiovanni, P.4
Fracanzani, A.L.5
Fraquelli, M.6
-
14
-
-
44249117598
-
Looking older: Fibroblast collapse and therapeutic implications
-
PMID:18490597
-
Fisher GJ, Varani J, Voorhees JJ. Looking older: fibroblast collapse and therapeutic implications. Arch Dermatol 2008; 144:666-72; PMID:18490597; http://dx.doi.org/10.1001/archderm.144.5.666.
-
(2008)
Arch Dermatol
, vol.144
, pp. 666-672
-
-
Fisher, G.J.1
Varani, J.2
Voorhees, J.J.3
-
15
-
-
75549086340
-
Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin
-
PMID:19641518
-
Quan T, Shao Y, He T, Voorhees JJ, Fisher GJ. Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin. J Invest Dermatol 2010; 130:415-24; PMID:19641518; http://dx.doi.org/10.1038/jid.2009.224.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 415-424
-
-
Quan, T.1
Shao, Y.2
He, T.3
Voorhees, J.J.4
Fisher, G.J.5
-
16
-
-
0038671795
-
Skin aging - Clinical aspects and pathogenesis
-
PMID:16285500
-
Schneider LA, Wlaschek M, Scharffetter-Kochanek K. [Skin aging - clinical aspects and pathogenesis]. J Dtsch Dermatol Ges 2003; 1:223-32; PMID:16285500; http://dx.doi.org/10.1046/j.1610-0387.2003.03515.x.
-
(2003)
J Dtsch Dermatol Ges
, vol.1
, pp. 223-232
-
-
Schneider, L.A.1
Wlaschek, M.2
Scharffetter-Kochanek, K.3
-
17
-
-
0346155876
-
Photoaging as a consequence of natural and therapeutic ultraviolet irradiation - Studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts
-
PMID:14698806
-
Wlaschek M, Ma W, Jansen-Dürr P, Scharffetter-Kochanek K. Photoaging as a consequence of natural and therapeutic ultraviolet irradiation - studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts. Exp Gerontol 2003; 38:1265-70; PMID:14698806; http://dx.doi.org/10.1016/j.exger. 2003.09.006.
-
(2003)
Exp Gerontol
, vol.38
, pp. 1265-1270
-
-
Wlaschek, M.1
Ma, W.2
Jansen-Dürr, P.3
Scharffetter-Kochanek, K.4
-
18
-
-
0027163464
-
Replicative senescence of human fibroblast-like cells in culture
-
PMID:8332640
-
Cristofalo VJ, Pignolo RJ. Replicative senescence of human fibroblast-like cells in culture. Physiol Rev 1993; 73:617-38; PMID:8332640.
-
(1993)
Physiol Rev
, vol.73
, pp. 617-638
-
-
Cristofalo, V.J.1
Pignolo, R.J.2
-
19
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
PMID:15734683
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005; 120:513-22; PMID:15734683; http://dx.doi.org/10.1016/j.cell.2005.02.003.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
20
-
-
0036829090
-
Cancer and aging: A model for the cancer promoting effects of the aging stroma
-
PMID:12200035
-
Krtolica A, Campisi J. Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 2002; 34:1401-14; PMID:12200035; http://dx.doi.org/10.1016/S1357-2725(02)00053-5.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1401-1414
-
-
Krtolica, A.1
Campisi, J.2
-
21
-
-
34047272525
-
The effect of cell-matrix interactions and aging on the malignant process
-
PMID:17433912
-
Labat-Robert J, Robert L. The effect of cell-matrix interactions and aging on the malignant process. Adv Cancer Res 2007; 98:221-59; PMID:17433912; http://dx.doi.org/10.1016/S0065-230X(06)98007-5.
-
(2007)
Adv Cancer Res
, vol.98
, pp. 221-259
-
-
Labat-Robert, J.1
Robert, L.2
-
22
-
-
67349149112
-
Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: Implications for ageing and hyperplastic scar formation
-
PMID:19306099
-
Treiber N, Peters T, Sindrilaru A, Huber R, Kohn M, Menke A, et al. Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: implications for ageing and hyperplastic scar formation. Arch Dermatol Res 2009; 301:273-87; PMID:19306099; http://dx.doi.org/10.1007/s00403-009-0935-9.
-
(2009)
Arch Dermatol Res
, vol.301
, pp. 273-287
-
-
Treiber, N.1
Peters, T.2
Sindrilaru, A.3
Huber, R.4
Kohn, M.5
Menke, A.6
-
23
-
-
0033520497
-
Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1
-
PMID:10464329
-
Wenk J, Brenneisen P, Wlaschek M, Poswig A, Briviba K, Oberley TD, et al. Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J Biol Chem 1999; 274:25869-76; PMID:10464329; http://dx.doi.org/10.1074/jbc.274.36.25869.
-
(1999)
J Biol Chem
, vol.274
, pp. 25869-25876
-
-
Wenk, J.1
Brenneisen, P.2
Wlaschek, M.3
Poswig, A.4
Briviba, K.5
Oberley, T.D.6
-
24
-
-
8544263882
-
Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metallo-proteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release
-
PMID:15308634
-
Wenk J, Schüller J, Hinrichs C, Syrovets T, Azoitei N, Podda M, et al. Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metallo-proteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release. J Biol Chem 2004; 279:45634-42; PMID:15308634; http://dx.doi.org/10.1074/jbc. M408893200.
-
(2004)
J Biol Chem
, vol.279
, pp. 45634-45642
-
-
Wenk, J.1
Schüller, J.2
Hinrichs, C.3
Syrovets, T.4
Azoitei, N.5
Podda, M.6
-
25
-
-
84859483420
-
Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin
-
Albany NY PMID:22278880
-
Velarde MC, Flynn JM, Day NU, Melov S, Campisi J. Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY) 2012; 4:3-12; PMID:22278880.
-
(2012)
Aging
, vol.4
, pp. 3-12
-
-
Velarde, M.C.1
Flynn, J.M.2
Day, N.U.3
Melov, S.4
Campisi, J.5
-
26
-
-
0033004248
-
Differences in electron transport potential, antioxidant defenses, and oxidant generation in young and senescent fetal lung fibroblasts (WI-38)
-
PMID:10362024
-
Allen RG, Tresini M, Keogh BP, Doggett DL, Cristofalo VJ. Differences in electron transport potential, antioxidant defenses, and oxidant generation in young and senescent fetal lung fibroblasts (WI-38). J Cell Physiol 1999; 180:114-22; PMID:10362024; http://dx.doi.org/10.1002/(SICI)1097-4652(199907)180: 1<114::AID-JCP133.0.CO;2-0.
-
(1999)
J Cell Physiol
, vol.180
, pp. 114-122
-
-
Allen, R.G.1
Tresini, M.2
Keogh, B.P.3
Doggett, D.L.4
Cristofalo, V.J.5
-
27
-
-
0036814967
-
Replicative senescence of human fibroblasts: The role of Ras-dependent signaling and oxidative stress
-
PMID:12470828
-
Hütter E, Unterluggauer H, Uberall F, Schramek H, Jansen-Dürr P. Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress. Exp Gerontol 2002; 37:1165-74; PMID:12470828; http://dx.doi.org/10.1016/S0531-5565(02)00136-5.
-
(2002)
Exp Gerontol
, vol.37
, pp. 1165-1174
-
-
Hütter, E.1
Unterluggauer, H.2
Uberall, F.3
Schramek, H.4
Jansen-Dürr, P.5
-
28
-
-
0030725872
-
UV-induced reactive oxygen species in photocarcinogenesis and photoaging
-
PMID:9426184
-
Scharffetter-Kochanek K, Wlaschek M, Brenneisen P, Schauen M, Blaudschun R, Wenk J. UV-induced reactive oxygen species in photocarcinogenesis and photoaging. Biol Chem 1997; 378:1247-57; PMID:9426184.
-
(1997)
Biol Chem
, vol.378
, pp. 1247-1257
-
-
Scharffetter-Kochanek, K.1
Wlaschek, M.2
Brenneisen, P.3
Schauen, M.4
Blaudschun, R.5
Wenk, J.6
-
29
-
-
24344447309
-
H2O2 accumulation by catalase reduction changes MAP kinase signaling in aged human skin in vivo
-
PMID:16098030
-
Shin MH, Rhie GE, Kim YK, Park CH, Cho KH, Kim KH, et al. H2O2 accumulation by catalase reduction changes MAP kinase signaling in aged human skin in vivo. J Invest Dermatol 2005; 125:221-9; PMID:16098030.
-
(2005)
J Invest Dermatol
, vol.125
, pp. 221-229
-
-
Shin, M.H.1
Rhie, G.E.2
Kim, Y.K.3
Park, C.H.4
Cho, K.H.5
Kim, K.H.6
-
30
-
-
34547955129
-
The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype
-
PMID:17574363
-
Borlon C, Debacq-Chainiaux F, Hinrichs C, Scharffetter-Kochanek K, Toussaint O, Wlaschek M. The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype. Exp Gerontol 2007; 42:911-23; PMID:17574363; http://dx.doi.org/10.1016/j.exger.2007. 04.009.
-
(2007)
Exp Gerontol
, vol.42
, pp. 911-923
-
-
Borlon, C.1
Debacq-Chainiaux, F.2
Hinrichs, C.3
Scharffetter-Kochanek, K.4
Toussaint, O.5
Wlaschek, M.6
-
31
-
-
0002026429
-
Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin
-
PMID:10029667
-
Lu CY, Lee HC, Fahn HJ, Wei YH. Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin. Mutat Res 1999; 423:11-21; PMID:10029667; http://dx.doi.org/10.1016/S0027-5107(98)00220-6.
-
(1999)
Mutat Res
, vol.423
, pp. 11-21
-
-
Lu, C.Y.1
Lee, H.C.2
Fahn, H.J.3
Wei, Y.H.4
-
32
-
-
0035254601
-
Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity
-
PMID:11165870
-
Meewes C, Brenneisen P, Wenk J, Kuhr L, Ma W, Alikoski J, et al. Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity. Free Radic Biol Med 2001; 30:238-47; PMID:11165870; http://dx.doi.org/10.1016/S0891-5849(00)00463-9.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 238-247
-
-
Meewes, C.1
Brenneisen, P.2
Wenk, J.3
Kuhr, L.4
Ma, W.5
Alikoski, J.6
-
33
-
-
0032935834
-
Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation
-
PMID:9886257
-
Poswig A, Wenk J, Brenneisen P, Wlaschek M, Hommel C, Quel G, et al. Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation. J Invest Dermatol 1999; 112:13-8; PMID:9886257; http://dx.doi.org/10.1046/j.1523-1747.1999.00465.x.
-
(1999)
J Invest Dermatol
, vol.112
, pp. 13-18
-
-
Poswig, A.1
Wenk, J.2
Brenneisen, P.3
Wlaschek, M.4
Hommel, C.5
Quel, G.6
-
34
-
-
0036846204
-
Induction of manganese superoxide dismutase in human dermal fibroblasts: A UV-B-mediated paracrine mechanism with the release of epidermal interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor alpha
-
PMID:12437453
-
Naderi-Hachtroudi L, Peters T, Brenneisen P, Meewes C, Hommel C, Razi-Wolf Z, et al. Induction of manganese superoxide dismutase in human dermal fibroblasts: a UV-B-mediated paracrine mechanism with the release of epidermal interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor alpha. Arch Dermatol 2002; 138:1473-9; PMID:12437453; http://dx.doi.org/10.1001/archderm. 138.11.1473.
-
(2002)
Arch Dermatol
, vol.138
, pp. 1473-1479
-
-
Naderi-Hachtroudi, L.1
Peters, T.2
Brenneisen, P.3
Meewes, C.4
Hommel, C.5
Razi-Wolf, Z.6
-
35
-
-
34447520043
-
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
-
PMID:17541420
-
Hu J, Van den Steen PE, Sang QX, Opdenakker G. Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases. Nat Rev Drug Discov 2007; 6:480-98; PMID:17541420; http://dx.doi.org/10.1038/nrd2308.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 480-498
-
-
Hu, J.1
Van Den Steen, P.E.2
Sang, Q.X.3
Opdenakker, G.4
-
36
-
-
68849096730
-
Matrix-degrading metalloproteinases in photoaging
-
PMID:19675548
-
Quan T, Qin Z, Xia W, Shao Y, Voorhees JJ, Fisher GJ. Matrix-degrading metalloproteinases in photoaging. J Investig Dermatol Symp Proc 2009; 14:20-4; PMID:19675548; http://dx.doi.org/10.1038/jidsymp.2009.8.
-
(2009)
J Investig Dermatol Symp Proc
, vol.14
, pp. 20-24
-
-
Quan, T.1
Qin, Z.2
Xia, W.3
Shao, Y.4
Voorhees, J.J.5
Fisher, G.J.6
-
37
-
-
58249116543
-
Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin
-
PMID:19116368
-
Fisher GJ, Quan T, Purohit T, Shao Y, Cho MK, He T, et al. Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. Am J Pathol 2009; 174:101-14; PMID:19116368; http://dx.doi.org/10.2353/ajpath.2009.080599.
-
(2009)
Am J Pathol
, vol.174
, pp. 101-114
-
-
Fisher, G.J.1
Quan, T.2
Purohit, T.3
Shao, Y.4
Cho, M.K.5
He, T.6
-
38
-
-
0033951993
-
Antioxidant and oxidative status in tissues of manganese superoxide dismutase transgenic mice
-
PMID:10699751
-
Ibrahim W, Lee US, Yen HC, St Clair DK, Chow CK. Antioxidant and oxidative status in tissues of manganese superoxide dismutase transgenic mice. Free Radic Biol Med 2000; 28:397-402; PMID:10699751; http://dx.doi.org/10.1016/ S0891-5849(99)00253-1.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 397-402
-
-
Ibrahim, W.1
Lee, U.S.2
Yen, H.C.3
St Clair, D.K.4
Chow, C.K.5
-
39
-
-
33846345418
-
Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase
-
PMID:17129739
-
Hu D, Cao P, Thiels E, Chu CT, Wu GY, Oury TD, et al. Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase. Neurobiol Learn Mem 2007; 87:372-84; PMID:17129739; http://dx.doi.org/10.1016/j.nlm.2006.10.003.
-
(2007)
Neurobiol Learn Mem
, vol.87
, pp. 372-384
-
-
Hu, D.1
Cao, P.2
Thiels, E.3
Chu, C.T.4
Wu, G.Y.5
Oury, T.D.6
-
40
-
-
70350439125
-
Overexpression of Mn superoxide dismutase does not increase life span in mice
-
PMID:19633237
-
Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, et al. Overexpression of Mn superoxide dismutase does not increase life span in mice. J Gerontol A Biol Sci Med Sci 2009; 64:1114-25; PMID:19633237; http://dx.doi.org/10.1093/gerona/glp100.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 1114-1125
-
-
Jang, Y.C.1
Pérez, V.I.2
Song, W.3
Lustgarten, M.S.4
Salmon, A.B.5
Mele, J.6
-
41
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
PMID:21109198
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 2010; 12:662-7; PMID:21109198; http://dx.doi.org/10.1016/j.cmet.2010.11.015.
-
(2010)
Cell Metab
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
42
-
-
0029838063
-
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
-
PMID:8790408
-
Lebovitz RM, Zhang H, Vogel H, Cartwright J Jr., Dionne L, Lu N, et al. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Acad Sci U S A 1996; 93:9782-7; PMID:8790408; http://dx.doi.org/10.1073/pnas.93.18.9782.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright Jr., J.4
Dionne, L.5
Lu, N.6
-
43
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
PMID:7493016
-
Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995; 11:376-81; PMID:7493016; http://dx.doi.org/10.1038/ng1295-376.
-
(1995)
Nat Genet
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
Olson, J.L.6
-
44
-
-
0035503501
-
Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics
-
PMID:11606622
-
Melov S, Doctrow SR, Schneider JA, Haberson J, Patel M, Coskun PE, et al. Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J Neurosci 2001; 21:8348-53; PMID:11606622.
-
(2001)
J Neurosci
, vol.21
, pp. 8348-8353
-
-
Melov, S.1
Doctrow, S.R.2
Schneider, J.A.3
Haberson, J.4
Patel, M.5
Coskun, P.E.6
-
45
-
-
66149167336
-
DNA damage response and cellular senescence in tissues of aging mice
-
PMID:19627270
-
Wang C, Jurk D, Maddick M, Nelson G, Martin-Ruiz C, von Zglinicki T. DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 2009; 8:311-23; PMID:19627270; http://dx.doi.org/10.1111/j.1474-9726.2009.00481. x.
-
(2009)
Aging Cell
, vol.8
, pp. 311-323
-
-
Wang, C.1
Jurk, D.2
Maddick, M.3
Nelson, G.4
Martin-Ruiz, C.5
Von Zglinicki, T.6
-
46
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
PMID:14679299
-
Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, et al. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics 2003; 16:29-37; PMID:14679299; http://dx.doi.org/10.1152/physiol-genomics.00122.2003.
-
(2003)
Physiol Genomics
, vol.16
, pp. 29-37
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
Pahlavani, M.4
Wolf, N.5
Thorpe, S.R.6
-
47
-
-
21044450045
-
Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo
-
PMID:15890620
-
Strassburger M, Bloch W, Sulyok S, Schüller J, Keist AF, Schmidt A, et al. Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo. Free Radic Biol Med 2005; 38:1458-70; PMID:15890620; http://dx.doi.org/10. 1016/j.freeradbiomed.2005.02.009.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 1458-1470
-
-
Strassburger, M.1
Bloch, W.2
Sulyok, S.3
Schüller, J.4
Keist, A.F.5
Schmidt, A.6
-
48
-
-
54149096363
-
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction
-
PMID:18596060
-
Wenzel P, Schuhmacher S, Kienhöfer J, Müller J, Hortmann M, Oelze M, et al. Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc Res 2008; 80:280-9; PMID:18596060; http://dx.doi.org/10.1093/cvr/cvn182.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 280-289
-
-
Wenzel, P.1
Schuhmacher, S.2
Kienhöfer, J.3
Müller, J.4
Hortmann, M.5
Oelze, M.6
-
49
-
-
77954682347
-
Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice
-
Albany NY PMID:20195488
-
Guachalla LM, Ju Z, Koziel R, von Figura G, Song Z, Fusser M, et al. Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. Aging (Albany NY) 2009; 1:303-15; PMID:20195488.
-
(2009)
Aging
, vol.1
, pp. 303-315
-
-
Guachalla, L.M.1
Ju, Z.2
Koziel, R.3
Von Figura, G.4
Song, Z.5
Fusser, M.6
-
50
-
-
79952599163
-
Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue
-
PMID:21108731
-
Treiber N, Maity P, Singh K, Kohn M, Keist AF, Ferchiu F, et al. Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue. Aging Cell 2011; 10:239-54; PMID:21108731; http://dx.doi.org/10.1111/j.1474-9726.2010.00658.x.
-
(2011)
Aging Cell
, vol.10
, pp. 239-254
-
-
Treiber, N.1
Maity, P.2
Singh, K.3
Kohn, M.4
Keist, A.F.5
Ferchiu, F.6
-
51
-
-
33748327046
-
p16INK4A is a robust in vivo biomarker of cellular aging in human skin
-
PMID:16911562
-
Ressler S, Bartkova J, Niederegger H, Bartek J, Scharffetter-Kochanek K, Jansen-Dürr P, et al. p16INK4A is a robust in vivo biomarker of cellular aging in human skin. Aging Cell 2006; 5:379-89; PMID:16911562; http://dx.doi.org/10.1111/j.1474-9726.2006.00231.x.
-
(2006)
Aging Cell
, vol.5
, pp. 379-389
-
-
Ressler, S.1
Bartkova, J.2
Niederegger, H.3
Bartek, J.4
Scharffetter-Kochanek, K.5
Jansen-Dürr, P.6
-
52
-
-
84900969225
-
Ink4a/Arf expression is a biomarker of aging
-
PMID:15520862
-
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, et al. Ink4a/Arf expression is a biomarker of aging. J Clin Invest 2004; 114:1299-307; PMID:15520862.
-
(2004)
J Clin Invest
, vol.114
, pp. 1299-1307
-
-
Krishnamurthy, J.1
Torrice, C.2
Ramsey, M.R.3
Kovalev, G.I.4
Al-Regaiey, K.5
Su, L.6
-
53
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
PMID:22048312
-
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011; 479:232-6; PMID:22048312; http://dx.doi.org/10.1038/nature10600.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
LeBrasseur, N.K.4
Childs, B.G.5
Van De Sluis, B.6
-
54
-
-
66649109663
-
Antioxidants prevent health-promoting effects of physical exercise in humans
-
PMID:19433800
-
Ristow M, Zarse K, Oberbach A, Klöting N, Birringer M, Kiehntopf M, et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A 2009; 106:8665-70; PMID:19433800; http://dx.doi.org/10.1073/pnas.0903485106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8665-8670
-
-
Ristow, M.1
Zarse, K.2
Oberbach, A.3
Klöting, N.4
Birringer, M.5
Kiehntopf, M.6
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