Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin

Journal of Investigative Dermatology

Volumn 130, Issue 2, 2010, Pages 415-424

  Quan, Taihao ^a   Shao, Yuan ^a   He, Tianyuan ^a   Voorhees, John J ^a   Fisher, Gary J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; PROCOLLAGEN; SMAD PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TYPE 1 PROCOLLAGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CUTANEOUS PARAMETERS; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; DERMIS; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; HUMANS; MIDDLE AGED; PHOSPHORYLATION; SKIN; SKIN AGING; SKIN PHYSIOLOGICAL PHENOMENA;

EID: 75549086340     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2009.224     Document Type: Article

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