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Volumn 190, Issue 1, 2013, Pages 392-400

Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response

Author keywords

[No Author keywords available]

Indexed keywords

[4 [4 [(2,3 DIHYDRO 1H INDEN 1 YL)AMINO] 7H PYRROLO[2,3 D]PYRIMIDIN 7 YL] 2 HYDROXYCYCLOPENTYLMETHYL] SULFAMATE; CULLIN; CYTOKINE; HYPOXIA INDUCIBLE FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; LIGASE; LIPOPOLYSACCHARIDE; PROTEIN; SENP8 PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84871837594     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202041     Document Type: Article
Times cited : (43)

References (54)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus, D. C., W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky. 2001. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 29: 1303-1310. (Pubitemid 32641789)
    • (2001) Critical Care Medicine , vol.29 , Issue.7 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 2
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • DOI 10.1056/NEJMoa022139
    • Martin, G. S., D. M. Mannino, S. Eaton, and M. Moss. 2003. The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348: 1546-1554. (Pubitemid 36437931)
    • (2003) New England Journal of Medicine , vol.348 , Issue.16 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 3
    • 79959854675 scopus 로고    scopus 로고
    • Biomarkers of endothelial dysfunction: Can they help us deciphering systemic inflammation and sepsis?
    • Paulus, P., C. Jennewein, and K. Zacharowski. 2011. Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis? Biomarkers 16(Suppl. 1): S11-S21.
    • (2011) Biomarkers , vol.16 , Issue.SUPPL. 1
    • Paulus, P.1    Jennewein, C.2    Zacharowski, K.3
  • 5
    • 78650878363 scopus 로고    scopus 로고
    • NF-κB, inflammation, and metabolic disease
    • Baker, R. G., M. S. Hayden, and S. Ghosh. 2011. NF-κB, inflammation, and metabolic disease. Cell Metab. 13: 11-22.
    • (2011) Cell Metab. , vol.13 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3
  • 6
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-κB signaling
    • Hayden, M. S., and S. Ghosh. 2008. Shared principles in NF-κB signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 7
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB - A pivotal transcription factor in chronic inflammatory diseases
    • DOI 10.1056/NEJM199704103361506
    • Barnes, P. J., and M. Karin. 1997. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336: 1066-1071. (Pubitemid 27163860)
    • (1997) New England Journal of Medicine , vol.336 , Issue.15 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 9
    • 37049002653 scopus 로고    scopus 로고
    • Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells
    • DOI 10.1091/mbc.E07-04-0391
    • Belaiba, R. S., S. Bonello, C. Zähringer, S. Schmidt, J. Hess, T. Kietzmann, and A. Görlach. 2007. Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells. Mol. Biol. Cell 18: 4691-4697. (Pubitemid 350246672)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.12 , pp. 4691-4697
    • BelAiba, R.S.1    Bonello, S.2    Zahringer, C.3    Schmidt, S.4    Hess, J.5    Kietzmann, T.6    Gorlach, A.7
  • 10
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Häcker, H., and M. Karin. 2006. Regulation and function of IKK and IKK-related kinases. Sci. STKE 2006: re13.
    • (2006) Sci. STKE , vol.2006
    • Häcker, H.1    Karin, M.2
  • 11
    • 80051625243 scopus 로고    scopus 로고
    • Oxygen sensing, homeostasis, and disease
    • Semenza, G. L. 2011. Oxygen sensing, homeostasis, and disease. N. Engl. J. Med. 365: 537-547.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 537-547
    • Semenza, G.L.1
  • 12
    • 77952092406 scopus 로고    scopus 로고
    • Hypoxia: An alarm signal during intestinal inflammation
    • Colgan, S. P., and C. T. Taylor. 2010. Hypoxia: an alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol 7: 281-287.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 281-287
    • Colgan, S.P.1    Taylor, C.T.2
  • 13
    • 84858797646 scopus 로고    scopus 로고
    • Hypoxia signaling during intestinal ischemia and inflammation
    • Grenz, A., E. Clambey, and H. K. Eltzschig. 2012. Hypoxia signaling during intestinal ischemia and inflammation. Curr. Opin. Crit. Care 18: 178-185.
    • (2012) Curr. Opin. Crit. Care , vol.18 , pp. 178-185
    • Grenz, A.1    Clambey, E.2    Eltzschig, H.K.3
  • 18
    • 0032522382 scopus 로고    scopus 로고
    • A novel protein modification pathway related to the ubiquitin system
    • DOI 10.1093/emboj/17.8.2208
    • Liakopoulos, D., G. Doenges, K. Matuschewski, and S. Jentsch. 1998. A novel protein modification pathway related to the ubiquitin system. EMBO J. 17: 2208-2214. (Pubitemid 28171906)
    • (1998) EMBO Journal , vol.17 , Issue.8 , pp. 2208-2214
    • Liakopoulos, D.1    Doenges, G.2    Matuschewski, K.3    Jentsch, S.4
  • 19
    • 44449129585 scopus 로고    scopus 로고
    • A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins
    • Jones, J., K. Wu, Y. Yang, C. Guerrero, N. Nillegoda, Z. Q. Pan, and L. Huang. 2008. A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. J. Proteome Res. 7: 1274-1287.
    • (2008) J. Proteome Res. , vol.7 , pp. 1274-1287
    • Jones, J.1    Wu, K.2    Yang, Y.3    Guerrero, C.4    Nillegoda, N.5    Pan, Z.Q.6    Huang, L.7
  • 20
    • 1342279417 scopus 로고    scopus 로고
    • Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins
    • DOI 10.1016/j.semcdb.2003.12.003
    • Parry, G., and M. Estelle. 2004. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Semin. Cell Dev. Biol. 15: 221-229. (Pubitemid 38251651)
    • (2004) Seminars in Cell and Developmental Biology , vol.15 , Issue.2 , pp. 221-229
    • Parry, G.1    Estelle, M.2
  • 21
    • 0037189519 scopus 로고    scopus 로고
    • β-TrCP-mediated ubiquitination and processing of the NF-κB precursor p105
    • β-TrCP-mediated ubiquitination and processing of the NF-κB precursor p105. J. Biol. Chem. 277: 23253-23259.
    • (2002) J. Biol. Chem. , vol.277 , pp. 23253-23259
    • Amir, R.E.1    Iwai, K.2    Ciechanover, A.3
  • 23
    • 33750702492 scopus 로고    scopus 로고
    • Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex
    • DOI 10.1593/neo.06520
    • Sufan, R. I., and M. Ohh. 2006. Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex. Neoplasia 8: 956-963. (Pubitemid 44706246)
    • (2006) Neoplasia , vol.8 , Issue.11 , pp. 956-963
    • Sufan, R.I.1    Ohh, M.2
  • 25
    • 67349221477 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and hypoxia-inducible factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis
    • Mariani, F., P. Sena, L. Marzona, M. Riccio, R. Fano, P. Manni, C. D. Gregorio, A. Pezzi, M. P. Leon, S. Monni, et al. 2009. Cyclooxygenase-2 and hypoxia-inducible factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis. Cancer Lett. 279: 221-229.
    • (2009) Cancer Lett. , vol.279 , pp. 221-229
    • Mariani, F.1    Sena, P.2    Marzona, L.3    Riccio, M.4    Fano, R.5    Manni, P.6    Gregorio, C.D.7    Pezzi, A.8    Leon, M.P.9    Monni, S.10
  • 26
    • 33847339352 scopus 로고    scopus 로고
    • Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation
    • DOI 10.1172/JCI30049
    • Khoury, J., J. C. Ibla, A. S. Neish, and S. P. Colgan. 2007. Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J. Clin. Invest. 117: 703-711. (Pubitemid 46348528)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 703-711
    • Khoury, J.1    Ibla, J.C.2    Neish, A.S.3    Colgan, S.P.4
  • 28
    • 0141426637 scopus 로고    scopus 로고
    • COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin ligases
    • DOI 10.1016/S0092-8674(03)00722-0
    • Cope, G. A., and R. J. Deshaies. 2003. COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114: 663-671. (Pubitemid 37186763)
    • (2003) Cell , vol.114 , Issue.6 , pp. 663-671
    • Cope, G.A.1    Deshaies, R.J.2
  • 31
    • 77956578834 scopus 로고    scopus 로고
    • MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: Rationale for treatment of NF-κB-dependent lymphoma
    • Milhollen, M. A., T. Traore, J. Adams-Duffy, M. P. Thomas, A. J. Berger, L. Dang, L. R. Dick, J. J. Garnsey, E. Koenig, S. P. Langston, et al. 2010. MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB-dependent lymphoma. Blood 116: 1515-1523.
    • (2010) Blood , vol.116 , pp. 1515-1523
    • Milhollen, M.A.1    Traore, T.2    Adams-Duffy, J.3    Thomas, M.P.4    Berger, A.J.5    Dang, L.6    Dick, L.R.7    Garnsey, J.J.8    Koenig, E.9    Langston, S.P.10
  • 33
    • 33749173298 scopus 로고    scopus 로고
    • Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFκkappaB-dependent transcription
    • Gao, F., J. Cheng, T. Shi, and E. T. Yeh. 2006. Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFκkappaB-dependent transcription. Nat. Cell Biol. 8: 1171-1177.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1171-1177
    • Gao, F.1    Cheng, J.2    Shi, T.3    Yeh, E.T.4
  • 34
    • 85047695603 scopus 로고    scopus 로고
    • Cell density mediated pericellular hypoxia leads to induction of HIF-1α via nitric oxide and Ras/MAP kinase mediated signaling pathways
    • DOI 10.1038/sj/onc/1204972
    • Sheta, E. A., H. Trout, J. J. Gildea, M. A. Harding, and D. Theodorescu. 2001. Cell density mediated pericellular hypoxia leads to induction of HIF-1α via nitric oxide and Ras/MAP kinase mediated signaling pathways. Oncogene 20: 7624-7634. (Pubitemid 33111862)
    • (2001) Oncogene , vol.20 , Issue.52 , pp. 7624-7634
    • Sheta, E.A.1    Trout, H.2    Gildea, J.J.3    Harding, M.A.4    Theodorescu, D.5
  • 35
    • 0032547817 scopus 로고    scopus 로고
    • Neutrophil-derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A(2B) receptor activation
    • DOI 10.1084/jem.188.8.1433
    • Lennon, P. F., C. T. Taylor, G. L. Stahl, and S. P. Colgan. 1998. Neutrophil-derived 5α-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J. Exp. Med. 188: 1433-1443. (Pubitemid 28489580)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.8 , pp. 1433-1443
    • Lennon, P.F.1    Taylor, C.T.2    Stahl, G.L.3    Colgan, S.P.4
  • 36
    • 59849113820 scopus 로고    scopus 로고
    • The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation
    • Kumar, A., H. Wu, L. S. Collier-Hyams, Y. M. Kwon, J. M. Hanson, and A. S. Neish. 2009. The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation. J. Immunol. 182: 538-546.
    • (2009) J. Immunol. , vol.182 , pp. 538-546
    • Kumar, A.1    Wu, H.2    Collier-Hyams, L.S.3    Kwon, Y.M.4    Hanson, J.M.5    Neish, A.S.6
  • 37
    • 35648973301 scopus 로고    scopus 로고
    • Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species
    • DOI 10.1038/sj.emboj.7601867, PII 7601867
    • Kumar, A., H.Wu, L. S. Collier-Hyams, J.M. Hansen, T. Li, K. Yamoah, Z. Q. Pan, D. P. Jones, and A. S. Neish. 2007. Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J. 26: 4457-4466. (Pubitemid 350036625)
    • (2007) EMBO Journal , vol.26 , Issue.21 , pp. 4457-4466
    • Kumar, A.1    Wu, H.2    Collier-Hyams, L.S.3    Hansen, J.M.4    Li, T.5    Yamoah, K.6    Pan, Z.-Q.7    Jones, D.P.8    Neish, A.S.9
  • 38
    • 79955898446 scopus 로고    scopus 로고
    • Neddylation-induced conformational control regulates cullin RING ligase activity in vivo
    • Boh, B. K., P. G. Smith, and T. Hagen. 2012. 2011. Neddylation-induced conformational control regulates cullin RING ligase activity in vivo. J. Mol. Biol. 409: 136-145.
    • (2011) J. Mol. Biol. , vol.409 , pp. 136-145
    • Boh, B.K.1    Smith, P.G.2    Hagen, T.3
  • 40
    • 77955639067 scopus 로고    scopus 로고
    • Endotoxin-induced HIF-1α stabilisation in equine endothelial cells: Synergistic action with hypoxia
    • Brooks, A. C., N. Menzies-Gow, S. R. Bailey, F. M. Cunningham, and J. Elliott. 2010. Endotoxin-induced HIF-1α stabilisation in equine endothelial cells: synergistic action with hypoxia. Inflamm. Res. 59: 689-698.
    • (2010) Inflamm. Res. , vol.59 , pp. 689-698
    • Brooks, A.C.1    Menzies-Gow, N.2    Bailey, S.R.3    Cunningham, F.M.4    Elliott, J.5
  • 41
    • 82155192318 scopus 로고    scopus 로고
    • Functional regulation of HIF-1α under normoxia: Is there more than post-translational regulation?
    • Kuschel, A., P. Simon, and S. Tug. 2012. Functional regulation of HIF-1α under normoxia: is there more than post-translational regulation? J. Cell. Physiol. 227: 514-524.
    • (2012) J. Cell. Physiol. , vol.227 , pp. 514-524
    • Kuschel, A.1    Simon, P.2    Tug, S.3
  • 42
    • 0035969236 scopus 로고    scopus 로고
    • The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice
    • Tateishi, K., M. Omata, K. Tanaka, and T. Chiba. 2001. The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J. Cell Biol. 155: 571-579. (Pubitemid 34289315)
    • (2001) Journal of Cell Biology , vol.155 , Issue.3 , pp. 571-579
    • Tateishi, K.1    Omata, M.2    Tanaka, K.3    Chiba, T.4
  • 43
    • 84862233291 scopus 로고    scopus 로고
    • Implications of protein post-translational modifications in IBD
    • Ehrentraut, S. F., and S. P. Colgan. 2012. Implications of protein post-translational modifications in IBD. Inflamm. Bowel Dis. 18: 1378-1388.
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 1378-1388
    • Ehrentraut, S.F.1    Colgan, S.P.2
  • 44
    • 1842538779 scopus 로고    scopus 로고
    • Oncogenic aberrations of cullin-dependent ubiquitin ligases
    • DOI 10.1038/sj.onc.1207413
    • Guardavaccaro, D., and M. Pagano. 2004. Oncogenic aberrations of cullin-dependent ubiquitin ligases. Oncogene 23: 2037-2049. (Pubitemid 38496733)
    • (2004) Oncogene , vol.23 , Issue.11 REV. ISS. 1 , pp. 2037-2049
    • Guardavaccaro, D.1    Pagano, M.2
  • 45
    • 70349339322 scopus 로고    scopus 로고
    • Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization
    • Merlet, J., J. Burger, J. E. Gomes, and L. Pintard. 2009. Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization. Cell. Mol. Life Sci. 66: 1924-1938.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 1924-1938
    • Merlet, J.1    Burger, J.2    Gomes, J.E.3    Pintard, L.4
  • 46
    • 79957907499 scopus 로고    scopus 로고
    • Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization
    • MacManus, C. F., E. L. Campbell, S. Keely, A. Burgess, D. J. Kominsky, and S. P. Colgan. 2011. Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization. FASEB J. 25: 1856-1864.
    • (2011) FASEB J. , vol.25 , pp. 1856-1864
    • MacManus, C.F.1    Campbell, E.L.2    Keely, S.3    Burgess, A.4    Kominsky, D.J.5    Colgan, S.P.6
  • 47
    • 24344476064 scopus 로고    scopus 로고
    • COPing with hypoxia
    • DOI 10.1016/j.semcdb.2005.03.002, PII S1084952105000534, Biology of Hypoxia and Myogenesis and Muscle Disease
    • Mikus, P., and W. Zundel. 2005. COPing with hypoxia. Semin. Cell Dev. Biol. 16: 462-473. (Pubitemid 41247870)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.4-5 , pp. 462-473
    • Mikus, P.1    Zundel, W.2
  • 48
    • 25444454359 scopus 로고    scopus 로고
    • Regulation of immune cells by local-tissue oxygen tension: HIF1a and adenosine receptors
    • DOI 10.1038/nri1685, PII NRI1685
    • Sitkovsky, M., and D. Lukashev. 2005. Regulation of immune cells by local-tissue oxygen tension: HIF1a and adenosine receptors. Nat. Rev. Immunol. 5: 712-721. (Pubitemid 43086172)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.9 , pp. 712-721
    • Sitkovsky, M.1    Lukashev, D.2
  • 52
    • 80054976363 scopus 로고    scopus 로고
    • Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis
    • Theilig, F., A. K. Enke, B. Scolari, D. Polzin, S. Bachmann, and R. Koesters. 2011. Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis. Am. J. Pathol. 179: 2177-2188.
    • (2011) Am. J. Pathol. , vol.179 , pp. 2177-2188
    • Theilig, F.1    Enke, A.K.2    Scolari, B.3    Polzin, D.4    Bachmann, S.5    Koesters, R.6
  • 53
    • 0036595292 scopus 로고    scopus 로고
    • Six at six: Interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days
    • Remick, D. G., G. R. Bolgos, J. Siddiqui, J. Shin, and J. A. Nemzek. 2002. Six at six: interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days. Shock 17: 463-467.
    • (2002) Shock , vol.17 , pp. 463-467
    • Remick, D.G.1    Bolgos, G.R.2    Siddiqui, J.3    Shin, J.4    Nemzek, J.A.5


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