-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus, D. C., W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky. 2001. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 29: 1303-1310. (Pubitemid 32641789)
-
(2001)
Critical Care Medicine
, vol.29
, Issue.7
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
DOI 10.1056/NEJMoa022139
-
Martin, G. S., D. M. Mannino, S. Eaton, and M. Moss. 2003. The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348: 1546-1554. (Pubitemid 36437931)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.16
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
3
-
-
79959854675
-
Biomarkers of endothelial dysfunction: Can they help us deciphering systemic inflammation and sepsis?
-
Paulus, P., C. Jennewein, and K. Zacharowski. 2011. Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis? Biomarkers 16(Suppl. 1): S11-S21.
-
(2011)
Biomarkers
, vol.16
, Issue.SUPPL. 1
-
-
Paulus, P.1
Jennewein, C.2
Zacharowski, K.3
-
4
-
-
77957745203
-
The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis
-
Shapiro, N. I., P. Schuetz, K. Yano, M. Sorasaki, S. M. Parikh, A. E. Jones, S. Trzeciak, L. Ngo, and W. C. Aird. 2010. The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis. Crit. Care 14: R182.
-
(2010)
Crit. Care
, vol.14
-
-
Shapiro, N.I.1
Schuetz, P.2
Yano, K.3
Sorasaki, M.4
Parikh, S.M.5
Jones, A.E.6
Trzeciak, S.7
Ngo, L.8
Aird, W.C.9
-
5
-
-
78650878363
-
NF-κB, inflammation, and metabolic disease
-
Baker, R. G., M. S. Hayden, and S. Ghosh. 2011. NF-κB, inflammation, and metabolic disease. Cell Metab. 13: 11-22.
-
(2011)
Cell Metab.
, vol.13
, pp. 11-22
-
-
Baker, R.G.1
Hayden, M.S.2
Ghosh, S.3
-
6
-
-
38849199203
-
Shared principles in NF-κB signaling
-
Hayden, M. S., and S. Ghosh. 2008. Shared principles in NF-κB signaling. Cell 132: 344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
7
-
-
0030615201
-
Nuclear factor-κB - A pivotal transcription factor in chronic inflammatory diseases
-
DOI 10.1056/NEJM199704103361506
-
Barnes, P. J., and M. Karin. 1997. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336: 1066-1071. (Pubitemid 27163860)
-
(1997)
New England Journal of Medicine
, vol.336
, Issue.15
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
8
-
-
19944432390
-
Hypoxia-induced neutrophil survival is mediated by HIF-1α-dependent NF-κB activity
-
DOI 10.1084/jem.20040624
-
Walmsley, S. R., C. Print, N. Farahi, C. Peyssonnaux, R. S. Johnson, T. Cramer, A. Sobolewski, A. M. Condliffe, A. S. Cowburn, N. Johnson, and E. R. Chilvers. 2005. Hypoxia-induced neutrophil survival is mediated by HIF-1α-dependent NF-κB activity. J. Exp. Med. 201: 105-115. (Pubitemid 40130088)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.1
, pp. 105-115
-
-
Walmsley, S.R.1
Print, C.2
Farahi, N.3
Peyssonnaux, C.4
Johnson, R.S.5
Cramer, T.6
Sobolewski, A.7
Condliffe, A.M.8
Cowburn, A.S.9
Johnson, N.10
Chilvers, E.R.11
-
9
-
-
37049002653
-
Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells
-
DOI 10.1091/mbc.E07-04-0391
-
Belaiba, R. S., S. Bonello, C. Zähringer, S. Schmidt, J. Hess, T. Kietzmann, and A. Görlach. 2007. Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells. Mol. Biol. Cell 18: 4691-4697. (Pubitemid 350246672)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.12
, pp. 4691-4697
-
-
BelAiba, R.S.1
Bonello, S.2
Zahringer, C.3
Schmidt, S.4
Hess, J.5
Kietzmann, T.6
Gorlach, A.7
-
10
-
-
39049183044
-
Regulation and function of IKK and IKK-related kinases
-
Häcker, H., and M. Karin. 2006. Regulation and function of IKK and IKK-related kinases. Sci. STKE 2006: re13.
-
(2006)
Sci. STKE
, vol.2006
-
-
Häcker, H.1
Karin, M.2
-
11
-
-
80051625243
-
Oxygen sensing, homeostasis, and disease
-
Semenza, G. L. 2011. Oxygen sensing, homeostasis, and disease. N. Engl. J. Med. 365: 537-547.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 537-547
-
-
Semenza, G.L.1
-
12
-
-
77952092406
-
Hypoxia: An alarm signal during intestinal inflammation
-
Colgan, S. P., and C. T. Taylor. 2010. Hypoxia: an alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol 7: 281-287.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 281-287
-
-
Colgan, S.P.1
Taylor, C.T.2
-
13
-
-
84858797646
-
Hypoxia signaling during intestinal ischemia and inflammation
-
Grenz, A., E. Clambey, and H. K. Eltzschig. 2012. Hypoxia signaling during intestinal ischemia and inflammation. Curr. Opin. Crit. Care 18: 178-185.
-
(2012)
Curr. Opin. Crit. Care
, vol.18
, pp. 178-185
-
-
Grenz, A.1
Clambey, E.2
Eltzschig, H.K.3
-
15
-
-
0032578855
-
Cleavage of the C-terminus of NEDD8 by UCH-L3
-
DOI 10.1006/bbrc.1998.9532
-
Wada, H., K. Kito, L. S. Caskey, E. T. Yeh, and T. Kamitani. 1998. Cleavage of the C-terminus of NEDD8 by UCH-L3. Biochem. Biophys. Res. Commun. 251: 688-692. (Pubitemid 28512771)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.251
, Issue.3
, pp. 688-692
-
-
Wada, H.1
Kito, K.2
Caskey, L.S.3
Yeh, E.T.H.4
Kamitani, T.5
-
16
-
-
4744338840
-
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8
-
DOI 10.1038/nsmb826
-
Huang, D. T., D. W. Miller, R. Mathew, R. Cassell, J. M. Holton, M. F. Roussel, and B. A. Schulman. 2004. A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Nat. Struct. Mol. Biol. 11: 927-935. (Pubitemid 39315295)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.10
, pp. 927-935
-
-
Huang, D.T.1
Miller, D.W.2
Mathew, R.3
Cassell, R.4
Holton, J.M.5
Roussel, M.F.6
Schulman, B.A.7
-
17
-
-
0038491277
-
NEDP1, a highly conserved cysteine protease that deNEDDylates cullins
-
DOI 10.1074/jbc.M212948200
-
Mendoza, H. M., L. N. Shen, C. Botting, A. Lewis, J. Chen, B. Ink, and R. T. Hay. 2003. NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins. J. Biol. Chem. 278: 25637-25643. (Pubitemid 36835317)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.28
, pp. 25637-25643
-
-
Mendoza, H.M.1
Shen, L.-N.2
Botting, C.3
Lewis, A.4
Chen, J.5
Ink, B.6
Hay, R.T.7
-
18
-
-
0032522382
-
A novel protein modification pathway related to the ubiquitin system
-
DOI 10.1093/emboj/17.8.2208
-
Liakopoulos, D., G. Doenges, K. Matuschewski, and S. Jentsch. 1998. A novel protein modification pathway related to the ubiquitin system. EMBO J. 17: 2208-2214. (Pubitemid 28171906)
-
(1998)
EMBO Journal
, vol.17
, Issue.8
, pp. 2208-2214
-
-
Liakopoulos, D.1
Doenges, G.2
Matuschewski, K.3
Jentsch, S.4
-
19
-
-
44449129585
-
A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins
-
Jones, J., K. Wu, Y. Yang, C. Guerrero, N. Nillegoda, Z. Q. Pan, and L. Huang. 2008. A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. J. Proteome Res. 7: 1274-1287.
-
(2008)
J. Proteome Res.
, vol.7
, pp. 1274-1287
-
-
Jones, J.1
Wu, K.2
Yang, Y.3
Guerrero, C.4
Nillegoda, N.5
Pan, Z.Q.6
Huang, L.7
-
20
-
-
1342279417
-
Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins
-
DOI 10.1016/j.semcdb.2003.12.003
-
Parry, G., and M. Estelle. 2004. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Semin. Cell Dev. Biol. 15: 221-229. (Pubitemid 38251651)
-
(2004)
Seminars in Cell and Developmental Biology
, vol.15
, Issue.2
, pp. 221-229
-
-
Parry, G.1
Estelle, M.2
-
21
-
-
0037189519
-
β-TrCP-mediated ubiquitination and processing of the NF-κB precursor p105
-
β-TrCP-mediated ubiquitination and processing of the NF-κB precursor p105. J. Biol. Chem. 277: 23253-23259.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23253-23259
-
-
Amir, R.E.1
Iwai, K.2
Ciechanover, A.3
-
23
-
-
33750702492
-
Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex
-
DOI 10.1593/neo.06520
-
Sufan, R. I., and M. Ohh. 2006. Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complex. Neoplasia 8: 956-963. (Pubitemid 44706246)
-
(2006)
Neoplasia
, vol.8
, Issue.11
, pp. 956-963
-
-
Sufan, R.I.1
Ohh, M.2
-
24
-
-
0037340247
-
Hypoxia inducible factor 1α and 2α overexpression in inflammatory bowel disease
-
DOI 10.1136/jcp.56.3.209
-
Giatromanolaki, A., E. Sivridis, E. Maltezos, D. Papazoglou, C. Simopoulos, K. C. Gatter, A. L. Harris, and M. I. Koukourakis. 2003. Hypoxia inducible factor 1α and 2α overexpression in inflammatory bowel disease. J. Clin. Pathol. 56: 209-213. (Pubitemid 36308037)
-
(2003)
Journal of Clinical Pathology
, vol.56
, Issue.3
, pp. 209-213
-
-
Giatromanolaki, A.1
Sivridis, E.2
Maltezos, E.3
Papazoglou, D.4
Simopoulos, C.5
Gatter, K.C.6
Harris, A.L.7
Koukourakis, M.I.8
-
25
-
-
67349221477
-
Cyclooxygenase-2 and hypoxia-inducible factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis
-
Mariani, F., P. Sena, L. Marzona, M. Riccio, R. Fano, P. Manni, C. D. Gregorio, A. Pezzi, M. P. Leon, S. Monni, et al. 2009. Cyclooxygenase-2 and hypoxia-inducible factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis. Cancer Lett. 279: 221-229.
-
(2009)
Cancer Lett.
, vol.279
, pp. 221-229
-
-
Mariani, F.1
Sena, P.2
Marzona, L.3
Riccio, M.4
Fano, R.5
Manni, P.6
Gregorio, C.D.7
Pezzi, A.8
Leon, M.P.9
Monni, S.10
-
26
-
-
33847339352
-
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation
-
DOI 10.1172/JCI30049
-
Khoury, J., J. C. Ibla, A. S. Neish, and S. P. Colgan. 2007. Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J. Clin. Invest. 117: 703-711. (Pubitemid 46348528)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 703-711
-
-
Khoury, J.1
Ibla, J.C.2
Neish, A.S.3
Colgan, S.P.4
-
27
-
-
0043208977
-
DEN1 is a dual function protease capable of processing the c terminus of Nedd8 and deconjugating hyper-neddylated CUL1
-
DOI 10.1074/jbc.M302888200
-
Wu, K., K. Yamoah, G. Dolios, T. Gan-Erdene, P. Tan, A. Chen, C. G. Lee, N. Wei, K. D. Wilkinson, R. Wang, and Z. Q. Pan. 2003. DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1. J. Biol. Chem. 278: 28882-28891. (Pubitemid 36935799)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.31
, pp. 28882-28891
-
-
Wu, K.1
Yamoah, K.2
Dolios, G.3
Gan-Erdene, T.4
Tan, P.5
Chen, A.6
Lee, C.-G.7
Wei, N.8
Wilkinson, K.D.9
Wang, R.10
Pan, Z.-Q.11
-
28
-
-
0141426637
-
COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin ligases
-
DOI 10.1016/S0092-8674(03)00722-0
-
Cope, G. A., and R. J. Deshaies. 2003. COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114: 663-671. (Pubitemid 37186763)
-
(2003)
Cell
, vol.114
, Issue.6
, pp. 663-671
-
-
Cope, G.A.1
Deshaies, R.J.2
-
29
-
-
0035906430
-
Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome
-
DOI 10.1126/science.1059780
-
Lyapina, S., G. Cope, A. Shevchenko, G. Serino, T. Tsuge, C. Zhou, D. A. Wolf, N. Wei, A. Shevchenko, and R. J. Deshaies. 2001. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 292: 1382-1385. (Pubitemid 32476226)
-
(2001)
Science
, vol.292
, Issue.5520
, pp. 1382-1385
-
-
Lyapina, S.1
Cope, G.2
Shevchenko, A.3
Serino, G.4
Tsuge, T.5
Zhou, C.6
Wolf, D.A.7
Wei, N.8
Shevchenko, A.9
Deshaies, R.J.10
-
30
-
-
64749098830
-
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
-
Soucy, T. A., P. G. Smith, M. A. Milhollen, A. J. Berger, J. M. Gavin, S. Adhikari, J. E. Brownell, K. E. Burke, D. P. Cardin, S. Critchley, et al. 2009. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature 458: 732-736.
-
(2009)
Nature
, vol.458
, pp. 732-736
-
-
Soucy, T.A.1
Smith, P.G.2
Milhollen, M.A.3
Berger, A.J.4
Gavin, J.M.5
Adhikari, S.6
Brownell, J.E.7
Burke, K.E.8
Cardin, D.P.9
Critchley, S.10
-
31
-
-
77956578834
-
MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: Rationale for treatment of NF-κB-dependent lymphoma
-
Milhollen, M. A., T. Traore, J. Adams-Duffy, M. P. Thomas, A. J. Berger, L. Dang, L. R. Dick, J. J. Garnsey, E. Koenig, S. P. Langston, et al. 2010. MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB-dependent lymphoma. Blood 116: 1515-1523.
-
(2010)
Blood
, vol.116
, pp. 1515-1523
-
-
Milhollen, M.A.1
Traore, T.2
Adams-Duffy, J.3
Thomas, M.P.4
Berger, A.J.5
Dang, L.6
Dick, L.R.7
Garnsey, J.J.8
Koenig, E.9
Langston, S.P.10
-
32
-
-
0026677532
-
HMEC-1: Establishment of an immortalized human microvascular endothelial cell line
-
Ades, E. W., F. J. Candal, R. A. Swerlick, V. G. George, S. Summers, D. C. Bosse, and T. J. Lawley. 1992. HMEC-1: establishment of an immortalized human microvascular endothelial cell line. J. Invest. Dermatol. 99: 683-690. (Pubitemid 23002027)
-
(1992)
Journal of Investigative Dermatology
, vol.99
, Issue.6
, pp. 683-690
-
-
Ades, E.W.1
Candal, F.J.2
Swerlick, R.A.3
George, V.G.4
Summers, S.5
Bosse, D.C.6
Lawley, T.J.7
-
33
-
-
33749173298
-
Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFκkappaB-dependent transcription
-
Gao, F., J. Cheng, T. Shi, and E. T. Yeh. 2006. Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFκkappaB-dependent transcription. Nat. Cell Biol. 8: 1171-1177.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1171-1177
-
-
Gao, F.1
Cheng, J.2
Shi, T.3
Yeh, E.T.4
-
34
-
-
85047695603
-
Cell density mediated pericellular hypoxia leads to induction of HIF-1α via nitric oxide and Ras/MAP kinase mediated signaling pathways
-
DOI 10.1038/sj/onc/1204972
-
Sheta, E. A., H. Trout, J. J. Gildea, M. A. Harding, and D. Theodorescu. 2001. Cell density mediated pericellular hypoxia leads to induction of HIF-1α via nitric oxide and Ras/MAP kinase mediated signaling pathways. Oncogene 20: 7624-7634. (Pubitemid 33111862)
-
(2001)
Oncogene
, vol.20
, Issue.52
, pp. 7624-7634
-
-
Sheta, E.A.1
Trout, H.2
Gildea, J.J.3
Harding, M.A.4
Theodorescu, D.5
-
35
-
-
0032547817
-
Neutrophil-derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A(2B) receptor activation
-
DOI 10.1084/jem.188.8.1433
-
Lennon, P. F., C. T. Taylor, G. L. Stahl, and S. P. Colgan. 1998. Neutrophil-derived 5α-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J. Exp. Med. 188: 1433-1443. (Pubitemid 28489580)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.8
, pp. 1433-1443
-
-
Lennon, P.F.1
Taylor, C.T.2
Stahl, G.L.3
Colgan, S.P.4
-
36
-
-
59849113820
-
The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation
-
Kumar, A., H. Wu, L. S. Collier-Hyams, Y. M. Kwon, J. M. Hanson, and A. S. Neish. 2009. The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation. J. Immunol. 182: 538-546.
-
(2009)
J. Immunol.
, vol.182
, pp. 538-546
-
-
Kumar, A.1
Wu, H.2
Collier-Hyams, L.S.3
Kwon, Y.M.4
Hanson, J.M.5
Neish, A.S.6
-
37
-
-
35648973301
-
Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species
-
DOI 10.1038/sj.emboj.7601867, PII 7601867
-
Kumar, A., H.Wu, L. S. Collier-Hyams, J.M. Hansen, T. Li, K. Yamoah, Z. Q. Pan, D. P. Jones, and A. S. Neish. 2007. Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J. 26: 4457-4466. (Pubitemid 350036625)
-
(2007)
EMBO Journal
, vol.26
, Issue.21
, pp. 4457-4466
-
-
Kumar, A.1
Wu, H.2
Collier-Hyams, L.S.3
Hansen, J.M.4
Li, T.5
Yamoah, K.6
Pan, Z.-Q.7
Jones, D.P.8
Neish, A.S.9
-
38
-
-
79955898446
-
Neddylation-induced conformational control regulates cullin RING ligase activity in vivo
-
Boh, B. K., P. G. Smith, and T. Hagen. 2012. 2011. Neddylation-induced conformational control regulates cullin RING ligase activity in vivo. J. Mol. Biol. 409: 136-145.
-
(2011)
J. Mol. Biol.
, vol.409
, pp. 136-145
-
-
Boh, B.K.1
Smith, P.G.2
Hagen, T.3
-
39
-
-
0033545860
-
Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to yon Hippel-Lindau tumor suppressor function
-
DOI 10.1073/pnas.96.10.5510
-
Liakopoulos, D., T. Büsgen, A. Brychzy, S. Jentsch, and A. Pause. 1999. Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function. Proc. Natl. Acad. Sci. USA 96: 5510-5515. (Pubitemid 29234648)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.10
, pp. 5510-5515
-
-
Liakopoulos, D.1
Busgen, T.2
Brychzy, A.3
Jentsch, S.4
Pause, A.5
-
40
-
-
77955639067
-
Endotoxin-induced HIF-1α stabilisation in equine endothelial cells: Synergistic action with hypoxia
-
Brooks, A. C., N. Menzies-Gow, S. R. Bailey, F. M. Cunningham, and J. Elliott. 2010. Endotoxin-induced HIF-1α stabilisation in equine endothelial cells: synergistic action with hypoxia. Inflamm. Res. 59: 689-698.
-
(2010)
Inflamm. Res.
, vol.59
, pp. 689-698
-
-
Brooks, A.C.1
Menzies-Gow, N.2
Bailey, S.R.3
Cunningham, F.M.4
Elliott, J.5
-
41
-
-
82155192318
-
Functional regulation of HIF-1α under normoxia: Is there more than post-translational regulation?
-
Kuschel, A., P. Simon, and S. Tug. 2012. Functional regulation of HIF-1α under normoxia: is there more than post-translational regulation? J. Cell. Physiol. 227: 514-524.
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 514-524
-
-
Kuschel, A.1
Simon, P.2
Tug, S.3
-
42
-
-
0035969236
-
The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice
-
Tateishi, K., M. Omata, K. Tanaka, and T. Chiba. 2001. The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J. Cell Biol. 155: 571-579. (Pubitemid 34289315)
-
(2001)
Journal of Cell Biology
, vol.155
, Issue.3
, pp. 571-579
-
-
Tateishi, K.1
Omata, M.2
Tanaka, K.3
Chiba, T.4
-
43
-
-
84862233291
-
Implications of protein post-translational modifications in IBD
-
Ehrentraut, S. F., and S. P. Colgan. 2012. Implications of protein post-translational modifications in IBD. Inflamm. Bowel Dis. 18: 1378-1388.
-
(2012)
Inflamm. Bowel Dis.
, vol.18
, pp. 1378-1388
-
-
Ehrentraut, S.F.1
Colgan, S.P.2
-
44
-
-
1842538779
-
Oncogenic aberrations of cullin-dependent ubiquitin ligases
-
DOI 10.1038/sj.onc.1207413
-
Guardavaccaro, D., and M. Pagano. 2004. Oncogenic aberrations of cullin-dependent ubiquitin ligases. Oncogene 23: 2037-2049. (Pubitemid 38496733)
-
(2004)
Oncogene
, vol.23
, Issue.11 REV. ISS. 1
, pp. 2037-2049
-
-
Guardavaccaro, D.1
Pagano, M.2
-
45
-
-
70349339322
-
Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization
-
Merlet, J., J. Burger, J. E. Gomes, and L. Pintard. 2009. Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization. Cell. Mol. Life Sci. 66: 1924-1938.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 1924-1938
-
-
Merlet, J.1
Burger, J.2
Gomes, J.E.3
Pintard, L.4
-
46
-
-
79957907499
-
Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization
-
MacManus, C. F., E. L. Campbell, S. Keely, A. Burgess, D. J. Kominsky, and S. P. Colgan. 2011. Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization. FASEB J. 25: 1856-1864.
-
(2011)
FASEB J.
, vol.25
, pp. 1856-1864
-
-
MacManus, C.F.1
Campbell, E.L.2
Keely, S.3
Burgess, A.4
Kominsky, D.J.5
Colgan, S.P.6
-
47
-
-
24344476064
-
COPing with hypoxia
-
DOI 10.1016/j.semcdb.2005.03.002, PII S1084952105000534, Biology of Hypoxia and Myogenesis and Muscle Disease
-
Mikus, P., and W. Zundel. 2005. COPing with hypoxia. Semin. Cell Dev. Biol. 16: 462-473. (Pubitemid 41247870)
-
(2005)
Seminars in Cell and Developmental Biology
, vol.16
, Issue.4-5
, pp. 462-473
-
-
Mikus, P.1
Zundel, W.2
-
48
-
-
25444454359
-
Regulation of immune cells by local-tissue oxygen tension: HIF1a and adenosine receptors
-
DOI 10.1038/nri1685, PII NRI1685
-
Sitkovsky, M., and D. Lukashev. 2005. Regulation of immune cells by local-tissue oxygen tension: HIF1a and adenosine receptors. Nat. Rev. Immunol. 5: 712-721. (Pubitemid 43086172)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.9
, pp. 712-721
-
-
Sitkovsky, M.1
Lukashev, D.2
-
49
-
-
85047685683
-
Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia
-
Synnestvedt, K., G. T. Furuta, K. M. Comerford, N. Louis, J. Karhausen, H. K. Eltzschig, K. R. Hansen, L. F. Thompson, and S. P. Colgan. 2002. Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J. Clin. Invest. 110: 993-1002.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 993-1002
-
-
Synnestvedt, K.1
Furuta, G.T.2
Comerford, K.M.3
Louis, N.4
Karhausen, J.5
Eltzschig, H.K.6
Hansen, K.R.7
Thompson, L.F.8
Colgan, S.P.9
-
50
-
-
33947191368
-
Protective role of ecto-5′-nucleiotidase (CD73) in renal ischemia
-
DOI 10.1681/ASN.2006101141
-
Grenz, A., H. Zhang, T. Eckle, M. Mittelbronn, M. Wehrmann, C. Köhle, D. Kloor, L. F. Thompson, H. Osswald, and H. K. Eltzschig. 2007. Protective role of ecto-5′-nucleotidase (CD73) in renal ischemia. J. Am. Soc. Nephrol. 18: 833-845. (Pubitemid 46434500)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.3
, pp. 833-845
-
-
Grenz, A.1
Zhang, H.2
Eckle, T.3
Mittelbronn, M.4
Wehrmann, M.5
Kohle, C.6
Kloor, D.7
Thompson, L.F.8
Osswald, H.9
Eltzschig, H.K.10
-
51
-
-
72949106456
-
Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney
-
Song, Y. R., S. J. You, Y. M. Lee, H. J. Chin, D. W. Chae, Y. K. Oh, K. W. Joo, J. S. Han, and K. Y. Na. 2010. Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney. Nephrol. Dial. Transplant. 25: 77-85.
-
(2010)
Nephrol. Dial. Transplant.
, vol.25
, pp. 77-85
-
-
Song, Y.R.1
You, S.J.2
Lee, Y.M.3
Chin, H.J.4
Chae, D.W.5
Oh, Y.K.6
Joo, K.W.7
Han, J.S.8
Na, K.Y.9
-
52
-
-
80054976363
-
Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis
-
Theilig, F., A. K. Enke, B. Scolari, D. Polzin, S. Bachmann, and R. Koesters. 2011. Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis. Am. J. Pathol. 179: 2177-2188.
-
(2011)
Am. J. Pathol.
, vol.179
, pp. 2177-2188
-
-
Theilig, F.1
Enke, A.K.2
Scolari, B.3
Polzin, D.4
Bachmann, S.5
Koesters, R.6
-
53
-
-
0036595292
-
Six at six: Interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days
-
Remick, D. G., G. R. Bolgos, J. Siddiqui, J. Shin, and J. A. Nemzek. 2002. Six at six: interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days. Shock 17: 463-467.
-
(2002)
Shock
, vol.17
, pp. 463-467
-
-
Remick, D.G.1
Bolgos, G.R.2
Siddiqui, J.3
Shin, J.4
Nemzek, J.A.5
-
54
-
-
84859588667
-
Cord blood interleukin-6 as a predictor of early-onset neonatal sepsis
-
Cernada, M., N. Badía, V. Modesto, R. Alonso, A. Mejías, S. Golombek, and M. Vento. 2012. Cord blood interleukin-6 as a predictor of early-onset neonatal sepsis. Acta Paediatr. 101: e203-e207.
-
(2012)
Acta Paediatr.
, vol.101
-
-
Cernada, M.1
Badía, N.2
Modesto, V.3
Alonso, R.4
Mejías, A.5
Golombek, S.6
Vento, M.7
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