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Volumn 25, Issue 6, 2011, Pages 1856-1864

Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization

Author keywords

Endothelia; Epithelia; Hypoxia; Inflammation; Mucosa

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; CULLIN; CULLIN 2; GAMMA INTERFERON; HYPOXIA INDUCIBLE FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; KERATINOCYTE CHEMOATTRACTANT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79957907499     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-170316     Document Type: Article
Times cited : (42)

References (40)
  • 1
    • 0142200971 scopus 로고    scopus 로고
    • The vascular contribution in the pathogenesis of inflammatory bowel disease
    • Hatoum, O. A., Miura, H., and Binion, D. G. (2003) The vascular contribution in the pathogenesis of inflammatory bowel disease. Am. J. Physiol. Heart Circ. Physiol. 285, H1791-H1796
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285
    • Hatoum, O.A.1    Miura, H.2    Binion, D.G.3
  • 3
    • 0034755535 scopus 로고    scopus 로고
    • Changes of colonic mucosal microcirculation and histology in two colitis models: An experimental study using intravital microscopy and a new histological scoring system
    • DOI 10.1023/A:1012334727509
    • Kruschewski, M., Foitzik, T., Perez-Canto, A., Hubotter, A., and Buhr, H. J. (2001) Changes of colonic mucosal microcirculation and histology in two colitis models: an experimental study using intravital microscopy and a new histological scoring system. Dig. Dis. Sci. 46, 2336-2343 (Pubitemid 33042330)
    • (2001) Digestive Diseases and Sciences , vol.46 , Issue.11 , pp. 2336-2343
    • Kruschewski, M.1    Foitzik, T.2    Perez-Canto, A.3    Hubotter, A.4    Buhr, H.J.5
  • 6
    • 43649093915 scopus 로고    scopus 로고
    • Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
    • Kaelin, W. G., Jr., and Ratcliffe, P. J. (2008) Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol. Cell 30, 393-402
    • (2008) Mol. Cell , vol.30 , pp. 393-402
    • Kaelin Jr., W.G.1    Ratcliffe, P.J.2
  • 7
    • 1342279417 scopus 로고    scopus 로고
    • Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins
    • DOI 10.1016/j.semcdb.2003.12.003
    • Parry, G., and Estelle, M. (2004) Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Semin. Cell. Dev. Biol. 15, 221-229 (Pubitemid 38251651)
    • (2004) Seminars in Cell and Developmental Biology , vol.15 , Issue.2 , pp. 221-229
    • Parry, G.1    Estelle, M.2
  • 9
    • 33845604971 scopus 로고    scopus 로고
    • HIF-dependent induction of adenosine A2B receptor in hypoxia
    • DOI 10.1096/fj.06-6419com
    • Kong, T., Westerman, K. A., Faigle, M., Eltzschig, H. K., and Colgan, S. P. (2006) HIF-dependent induction of adenosine A2B receptor in hypoxia. FASEB J. 20, 2242-2250 (Pubitemid 44953854)
    • (2006) FASEB Journal , vol.20 , Issue.13 , pp. 2242-2250
    • Kong, T.1    Westerman, K.A.2    Faigle, M.3    Eltzschig, H.K.4    Colgan, S.P.5
  • 10
    • 0024778374 scopus 로고
    • Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line
    • LeBivic, A., Francisco, X. R., and Rodriguez-Boulan, E. (1989) Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line. Proc. Natl. Acad. Sci. U. S. A. 86, 9313-9317
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 9313-9317
    • LeBivic, A.1    Francisco, X.R.2    Rodriguez-Boulan, E.3
  • 12
    • 0034457191 scopus 로고    scopus 로고
    • Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: Receptor subtype involved and signaling mechanism
    • Andreis, P. G., Markowska, A., Champion, H. C., Mazzocchi, G., Malendowicz, L. K., and Nussdorfer, G. G. (2000) Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: receptor subtype involved and signaling mechanism. Endocrinology 141, 2098-2104
    • (2000) Endocrinology , vol.141 , pp. 2098-2104
    • Andreis, P.G.1    Markowska, A.2    Champion, H.C.3    Mazzocchi, G.4    Malendowicz, L.K.5    Nussdorfer, G.G.6
  • 13
    • 0037445798 scopus 로고    scopus 로고
    • Adrenomedullin is an autocrine/paracrine growth factor for rat vascular smooth muscle cells
    • DOI 10.1016/S0167-0115(03)00036-3
    • Shichiri, M., Fukai, N., Ozawa, N., Iwasaki, H., and Hirata, Y. (2003) Adrenomedullin is an autocrine/paracrine growth factor for rat vascular smooth muscle cells. Regul. Pept. 112, 167-173 (Pubitemid 36351614)
    • (2003) Regulatory Peptides , vol.112 , Issue.1-3 , pp. 167-173
    • Shichiri, M.1    Fukai, N.2    Ozawa, N.3    Iwasaki, H.4    Hirata, Y.5
  • 14
    • 0035853722 scopus 로고    scopus 로고
    • Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners
    • Pio, R., Martinez, A., Unsworth, E. J., Kowalak, J. A., Bengoechea, J. A., Zipfel, P. F., Elsasser, T. H., and Cuttitta, F. (2001) Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners. J. Biol. Chem. 276, 12292-12300
    • (2001) J. Biol. Chem. , vol.276 , pp. 12292-12300
    • Pio, R.1    Martinez, A.2    Unsworth, E.J.3    Kowalak, J.A.4    Bengoechea, J.A.5    Zipfel, P.F.6    Elsasser, T.H.7    Cuttitta, F.8
  • 15
    • 24344476064 scopus 로고    scopus 로고
    • COPing with hypoxia
    • DOI 10.1016/j.semcdb.2005.03.002, PII S1084952105000534, Biology of Hypoxia and Myogenesis and Muscle Disease
    • Mikus, P., and Zundel, W. (2005) COPing with hypoxia. Semin. Cell. Dev. Biol. 16, 462-473 (Pubitemid 41247870)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.4-5 , pp. 462-473
    • Mikus, P.1    Zundel, W.2
  • 17
    • 37349048502 scopus 로고    scopus 로고
    • Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition
    • DOI 10.1053/j.gastro.2007.09.033, PII S001650850701743X
    • Robinson, A., Keely, S., Karhausen, J., Gerich, M. E., Furuta, G. T., and Colgan, S. P. (2008) Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition. Gastroenterology 134, 145-155 (Pubitemid 350309309)
    • (2008) Gastroenterology , vol.134 , Issue.1 , pp. 145-155
    • Robinson, A.1    Keely, S.2    Karhausen, J.3    Gerich, M.E.4    Furuta, G.T.5    Colgan, S.P.6
  • 18
    • 0032504165 scopus 로고    scopus 로고
    • Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes
    • Cormier-Regard, S., Nguyen, S. V., and Claycomb, W. C. (1998) Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes. J. Biol. Chem. 273, 17787-17792
    • (1998) J. Biol. Chem. , vol.273 , pp. 17787-17792
    • Cormier-Regard, S.1    Nguyen, S.V.2    Claycomb, W.C.3
  • 21
    • 33748852946 scopus 로고    scopus 로고
    • The central role of adrenomedullin in host defense
    • DOI 10.1189/jlb.0206123
    • Zudaire, E., Portal-Nunez, S., and Cuttitta, F. (2006) The central role of adrenomedullin in host defense. J. Leukoc. Biol. 80, 237-244 (Pubitemid 44841804)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.2 , pp. 237-244
    • Zudaire, E.1    Portal-Nunez, S.2    Cuttitta, F.3
  • 22
    • 77949355583 scopus 로고    scopus 로고
    • Structure-function relationships of the N-terminus of receptor activity-modifying proteins
    • Qi, T., and Hay, D. L. (2010) Structure-function relationships of the N-terminus of receptor activity-modifying proteins. Br. J. Pharmacol. 159, 1059-1068
    • (2010) Br. J. Pharmacol. , vol.159 , pp. 1059-1068
    • Qi, T.1    Hay, D.L.2
  • 23
    • 6344237420 scopus 로고    scopus 로고
    • Adrenomedullin receptors: Pharmacological features and possible pathophysiological roles
    • DOI 10.1016/j.peptides.2004.06.002, PII S0196978104002542
    • Kuwasako, K., Cao, Y. N., Nagoshi, Y., Kitamura, K., and Eto, T. (2004) Adrenomedullin receptors: pharmacological features and possible pathophysiological roles. Peptides 25, 2003-2012 (Pubitemid 39389197)
    • (2004) Peptides , vol.25 , Issue.11 , pp. 2003-2012
    • Kuwasako, K.1    Cao, Y.-N.2    Nagoshi, Y.3    Kitamura, K.4    Eto, T.5
  • 24
    • 0035106894 scopus 로고    scopus 로고
    • Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells
    • DOI 10.1210/en.142.2.564
    • Iwasaki, H., Shichiri, M., Marumo, F., and Hirata, Y. (2001) Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells. Endocrinology 142, 564-572 (Pubitemid 32222404)
    • (2001) Endocrinology , vol.142 , Issue.2 , pp. 564-572
    • Iwasaki, H.1    Shichiri, M.2    Marumo, F.3    Hirata, Y.4
  • 25
    • 33646394319 scopus 로고    scopus 로고
    • Gs and Gi coupling of adrenomedullin in adult rat ventricular myocytes
    • Mittra, S., and Bourreau, J. P. (2006) Gs and Gi coupling of adrenomedullin in adult rat ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol. 290, H1842-H1847
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.290
    • Mittra, S.1    Bourreau, J.P.2
  • 26
    • 0038018585 scopus 로고    scopus 로고
    • Adrenomedullin provokes endothelial Akt activation and promotes vascular regeneration both in vitro and in vivo
    • DOI 10.1016/S0014-5793(03)00484-8
    • Miyashita, K., Itoh, H., Sawada, N., Fukunaga, Y., Sone, M., Yamahara, K., Yurugi-Kobayashi, T., Park, K., and Nakao, K. (2003) Adrenomedullin provokes endothelial Akt activation and promotes vascular regeneration both in vitro and in vivo. FEBS Lett. 544, 86-92 (Pubitemid 36628041)
    • (2003) FEBS Letters , vol.544 , Issue.1-3 , pp. 86-92
    • Miyashita, K.1    Itoh, H.2    Sawada, N.3    Fukunaga, Y.4    Sone, M.5    Yamahara, K.6    Yurugi-Kobayashi, T.7    Park, K.8    Nakao, K.9
  • 28
    • 33646779859 scopus 로고    scopus 로고
    • Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease
    • DOI 10.1136/gut.2005.084525
    • Gonzalez-Rey, E., Fernandez-Martin, A., Chorny, A., and Delgado, M. (2006) Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease. Gut 55, 824-832 (Pubitemid 43764553)
    • (2006) Gut , vol.55 , Issue.6 , pp. 824-832
    • Gonzalez-Rey, E.1    Fernandez-Martin, A.2    Chorny, A.3    Delgado, M.4
  • 29
    • 54049122543 scopus 로고    scopus 로고
    • Acute and chronic responses associated with adrenomedullin administration in experimental colitis
    • Talero, E., Sanchez-Fidalgo, S., de la Lastra, C. A., Illanes, M., Calvo, J. R., and Motilva, V. (2008) Acute and chronic responses associated with adrenomedullin administration in experimental colitis. Peptides 29, 2001-2012
    • (2008) Peptides , vol.29 , pp. 2001-2012
    • Talero, E.1    Sanchez-Fidalgo, S.2    De La Lastra, C.A.3    Illanes, M.4    Calvo, J.R.5    Motilva, V.6
  • 30
    • 33847026157 scopus 로고    scopus 로고
    • Adrenomedullin protects from experimental arthritis by down-regulating inflammation and Th1 response and inducing regulatory T cells
    • DOI 10.2353/ajpath.2007.060596
    • Gonzalez-Rey, E., Chorny, A., O'Valle, F., and Delgado, M. (2007) Adrenomedullin protects from experimental arthritis by down-regulating inflammation and Th1 response and inducing regulatory T cells. Am. J. Pathol. 170, 263-271 (Pubitemid 47339205)
    • (2007) American Journal of Pathology , vol.170 , Issue.1 , pp. 263-271
    • Gonzalez-Rey, E.1    Chorny, A.2    O'Valle, F.3    Delgado, M.4
  • 31
    • 0042203519 scopus 로고    scopus 로고
    • Transcriptional regulation of the CRLR gene in human microvascular endothelial cells by hypoxia
    • Nikitenko, L. L., Smith, D. M., Bicknell, R., and Rees, M. C. (2003) Transcriptional regulation of the CRLR gene in human microvascular endothelial cells by hypoxia. FASEB J. 17, 1499-1501
    • (2003) FASEB J. , vol.17 , pp. 1499-1501
    • Nikitenko, L.L.1    Smith, D.M.2    Bicknell, R.3    Rees, M.C.4
  • 35
    • 73449115750 scopus 로고    scopus 로고
    • Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation
    • Eltzschig, H. K., Rivera-Nieves, J., and Colgan, S. P. (2009) Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation. Expert Opin. Ther. Targets 13, 1267-1277
    • (2009) Expert Opin. Ther. Targets , vol.13 , pp. 1267-1277
    • Eltzschig, H.K.1    Rivera-Nieves, J.2    Colgan, S.P.3
  • 36
    • 33847339352 scopus 로고    scopus 로고
    • Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation
    • DOI 10.1172/JCI30049
    • Khoury, J., Ibla, J. C., Neish, A. S., and Colgan, S. P. (2007) Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J. Clin. Invest. 117, 703-711 (Pubitemid 46348528)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 703-711
    • Khoury, J.1    Ibla, J.C.2    Neish, A.S.3    Colgan, S.P.4
  • 39
    • 70349309435 scopus 로고    scopus 로고
    • Selective induction of integrin beta1 by hypoxia-inducible factor: Implications for wound healing
    • Keely, S., Glover, L. E., Macmanus, C. F., Campbell, E. L., Scully, M. M., Furuta, G. T., and Colgan, S. P. (2009) Selective induction of integrin beta1 by hypoxia-inducible factor: implications for wound healing. FASEB J. 23, 1338-1346
    • (2009) FASEB J. , vol.23 , pp. 1338-1346
    • Keely, S.1    Glover, L.E.2    Macmanus, C.F.3    Campbell, E.L.4    Scully, M.M.5    Furuta, G.T.6    Colgan, S.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.