COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin ligases

Cell

Volumn 114, Issue 6, 2003, Pages 663-671

  Cope, Gregory A ^a   Deshaies, Raymond J ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COP9 SIGNALOSOME; LIGASE; PROTEASOME; PROTEIN; PROTEIN KINASE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

CELL CYCLE; CELL DIFFERENTIATION; CYTOSKELETON; DEVELOPMENT; ENZYME ACTIVITY; NONHUMAN; PHOTOMORPHOGENESIS; PLANT; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; YEAST;

EUKARYOTA;

EID: 0141426637     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00722-0     Document Type: Review

References (57)

1. Ayad N.G., Rankin S., Murakami M., Jebanathirajah J., Gygi S., Kirschner M.W. Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC. Cell. 113:2003;101-113.
2. Azevedo C., Sadanandom A., Kitagawa K., Freialdenhoven A., Shirasu K., Schulze-Lefert P. The RAR1 interactor SGT1, an essential component of R gene-triggered disease resistance. Science. 295:2002;2073-2076.
3. Claret F.X., Hibi M., Dhut S., Toda T., Karin M. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature. 383:1996;453-457.
4. Cope G.A., Suh G.S., Aravind L., Schwarz S.E., Zipursky S.L., Koonin E.V., Deshaies R.J. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science. 298:2002;608-611.
5. Davis M., Hatzubai A., Andersen J.S., Ben-Shushan E., Fisher G.Z., Yaron A., Bauskin A., Mercurio F., Mann M., Ben-Neriah Y. Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U. Genes Dev. 16:2002;439-451.
6. Deffenbaugh A., Scaglione K., Zhang L., Moore J.M., Buranda T., Sklar L.A., Skowyra D. Release of ubiquitin-charged Cdc34-S∼Ub from the RING domain is essential for ubiquitination of the SCFCdc4-bound substrate Sic1. Cell. 114:2003;611-622.
7. Deshaies R.J. SCF and Cullin/Ring H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 15:1999;435-467.
8. Deshaies R.J., Meyerowitz E. COP1 patrols the night beat. Nat. Cell Biol. 2:2000;E102-E104.
9. Doronkin S., Djagaeva I., Beckendorf S.K. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development. 129:2002;5053-5064.
10. Doronkin S., Djagaeva I., Beckendorf S.K. The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis. Dev. Cell. 4:2003;699-710.
11. Feng S., Ma L., Wang X., Xie D., Dinesh-Kumar S.P., Wei N., Deng X.W. The COP9 Signalosome Interacts Physically with SCF(COI1) and Modulates Jasmonate Responses. Plant Cell. 15:2003;1083-1094.
12. Galan J.M., Peter M. Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism. Proc. Natl. Acad. Sci. USA. 96:1999;9124-9129.
13. Gray W.M., del Pozo J.C., Walker L., Hobbie L., Risseeuw E., Banks T., Crosby W.L., Yang M., Ma H., Estelle M. Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes Dev. 13:1999;1678-1691.
14. Gray W.M., Kepinski S., Rouse D., Leyser O., Estelle M. Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins. Nature. 414:2001;271-276.
15. Groisman R., Polanowska J., Kuraoka I., Sawada J., Saijo M., Drapkin R., Kisselev A.F., Tanaka K., Nakatani Y. The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage. Cell. 113:2003;357-367.
16. Hwang J.W., Min K.W., Tamura T., Yoon J.B. TIP120A associates with unneddylated cullin 1 and regulates its neddylation. FEBS Lett. 541:2003;102-108.
17. Kawakami T., Chiba T., Suzuki T., Iwai K., Yamanaka K., Minato N., Suzuki H., Shimbara N., Hidaka Y., Osaka F.et al. NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J. 20:2001;4003-4012.
18. Kleemann R., Hausser A., Geiger G., Mischke R., Burger-Kentischer A., Flieger O., Johannes F.J., Roger T., Calandra T., Kapurniotu A.et al. Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature. 408:2000;211-216.
19. Lammer D., Mathias N., Laplaza J.M., Jiang W., Liu Y., Callis J., Goebl M., Estelle M. Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev. 12:1998;914-926.
20. Liakopoulos D., Doenges G., Matuschewski K., Jentsch S. A novel protein modification pathway related to the ubiquitin system. EMBO J. 17:1998;2208-2214.
21. Liu J., Furukawa M., Matsumoto T., Xiong Y. NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol. Cell. 10:2002;1511-1518.
22. Liu C., Powell K.A., Mundt K., Wu L., Carr A.M., Caspari T. Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. Genes Dev. 9:2003;1130-1140.
23. Lyapina S., Cope G., Shevchenko A., Serino G., Tsuge T., Zhou C., Wolf D.A., Wei N., Deshaies R.J. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science. 292:2001;1382-1385.
24. Margottin-Goguet F., Hsu J.Y., Loktev A., Hsieh H.M., Reimann J.D., Jackson P.K. Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Dev. Cell. 4:2003;813-826.
25. Maytal-Kivity V., Pick E., Piran R., Hofmann K., Glickman M.H. The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes. Int. J. Biochem. Cell Biol. 35:2003;706-715.
26. Min K.W., Hwang J.W., Lee J.S., Park Y., Tamura T.A., Yoon J.B. TIP120A associates with cullins and modulates ubiquitin ligase activity. J. Biol. Chem. 278:2003;15905-15910.
27. Mundt K.E., Porte J., Murray J.M., Brikos C., Christensen P.U., Caspari T., Hagan I.M., Millar J.B., Simanis V., Hofmann K., Carr A.M. The COP9/signalosome complex is conserved in fission yeast and has a role in S phase. Curr. Biol. 9:1999;1427-1430.
28. Mundt K.E., Liu C., Carr A.M. Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes. Mol. Biol. Cell. 13:2002;493-502.
29. Nordgard O., Dahle O., Andersen T.O., Gabrielsen O.S. JAB1/CSN5 interacts with the GAL4 DNA binding domain. a note of caution about two-hybrid interactions Biochimie. 83:2001;969-971.
30. Oron E., Mannervik M., Rencus S., Harari-Steinberg O., Neuman-Silberberg S., Segal D., Chamovitz D.A. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development. 129:2002;4399-4409.
31. Oshikawa K., Matsumoto M., Yada M., Kamura T., Hatakeyama S., Nakayama K.I. Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1. Biochem. Biophys. Res. Commun. 303:2003;1209-1216.
32. Osterlund M.T., Ang L.H., Deng X.W. The role of COP1 in repression of Arabidopsis photomorphogenic development. Trends Cell Biol. 9:1999;113-118.
33. Osterlund M.T., Hardtke C.S., Wei N., Deng X.W. Targeted destabilization of HY5 during light-regulated development of Arabidopsis. Nature. 405:2000;462-466.
34. Peng Z., Shen Y., Feng S., Wang X., Chitteti B.N., Vierstra R.D., Deng X.W. Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo. Curr. Biol. 13:2003;R504-R505.
35. Petroski M.D., Deshaies R.J. Context of multiubiquitin chain attachment influences the rate of Sic1 degradation. Mol. Cell. 11:2003;1435-1444.
36. Pintard L., Kurz T., Glaser S., Willis J.H., Peter M., Bowerman B. Neddylation and Deneddylation of CUL-3 Is Required to Target MEI-1/Katanin for Degradation at the Meiosis-to-Mitosis Transition in C. elegans. Curr. Biol. 13:2003;911-921.
37. Podust V.N., Brownell J.E., Gladysheva T.B., Luo R.S., Wang C., Coggins M.B., Pierce J.W., Lightcap E.S., Chau V. A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. Proc. Natl. Acad. Sci. USA. 97:2000;4579-4584.
38. Read M.A., Brownell J.E., Gladysheva T.B., Hottelet M., Parent L.A., Coggins M.B., Pierce J.W., Podust V.N., Luo R.S., Chau V., Palombella V.J. Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha. Mol. Cell. Biol. 20:2000;2326-2333.
39. Schwechheimer C., Deng X.W. COP9 signalosome revisited. a novel mediator of protein degradation Trends Cell Biol. 11:2001;420-426.
40. Schwechheimer C., Serino G., Callis J., Crosby W.L., Lyapina S., Deshaies R.J., Gray W.M., Estelle M., Deng X.W. Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science. 292:2001;1379-1382.
41. Smith P., Leung-Chiu W.M., Montgomery R., Orsborn A., Kuznicki K., Gressman-Coberly E., Mutapcic L., Bennett K. The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein. Dev. Biol. 251:2002;333-347.
42. Suh G.S., Poeck B., Chouard T., Oron E., Segal D., Chamovitz D.A., Zipursky S.L. Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells. Neuron. 33:2002;35-46.
43. Sun Y., Wilson M.P., Majerus P.W. Inositol 1,3,4-trisphosphate 5/ 6-kinase associates with the COP9 signalosome by binding to CSN1. J. Biol. Chem. 277:2002;45759-45764.
44. Tomoda K., Kubota Y., Kato J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature. 398:1999;160-165.
45. Tomoda K., Kubota Y., Arata Y., Mori S., Maeda M., Tanaka T., Yoshida M., Yoneda-Kato N., Kato J.Y. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J. Biol. Chem. 277:2002;2302-2310.
46. Uhle S., Medalia O., Waldron R., Dumdey R., Henklein P., Bech-Otschir D., Huang X., Berse M., Sperling J., Schade R., Dubiel W. Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. EMBO J. 22:2003;1302-1312.
47. Wang H., Ma L.G., Li J.M., Zhao H.Y., Deng X.W. Direct interaction of Arabidopsis cryptochromes with COP1 in light control development. Science. 294:2001;154-158.
48. Wang X., Feng S., Nakayama N., Crosby W.L., Irish V., Deng X.W., Wei N. The COP9 Signalosome Interacts with SCF(UFO) and Participates in Arabidopsis Flower Development. Plant Cell. 15:2003;1071-1082.
49. Wee S., Hetfeld B., Dubiel W., Wolf D.A. Conservation of the COP9/signalosome in budding yeast. BMC Genet. 3:2002;15.
50. Wei N., Deng X.W. Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human. Trends Genet. 15:1999;98-103.
51. Wilson M.P., Sun Y., Cao L., Majerus P.W. Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2. J. Biol. Chem. 276:2001;40998-41004.
52. Wu K., Chen A., Pan Z.Q. Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization. J. Biol. Chem. 275:2000;32317-32324.
53. Wu G., Xu G., Schulman B.A., Jeffrey P.D., Harper J.W., Pavletich N.P. Structure of a beta-TrCP1-Skp1-beta-catenin complex. destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase Mol. Cell. 11:2003;1445-1456.
54. Yang X., Menon S., Lykke-Andersen K., Tsuge T., Di X., Wang X., Rodriguez-Suarez R.J., Zhang H., Wei N. The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1. Curr. Biol. 12:2002;667-672.
55. Zheng J., Yang X., Harrell J.M., Ryzhikov S., Shim E.H., Lykke-Andersen K., Wei N., Sun H., Kobayashi R., Zhang H. CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Mol. Cell. 10:2002;1519-1526.
56. Zhou P., Howley P.M. Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol. Cell. 2:1998;571-580.
57. Zhou C., Wee S., Rhee E., Naumann M., Dubiel W., Wolf D.A. Fission Yeast COP9/Signalosome Suppresses Cullin Activity through Recruitment of the Deubiquitylating Enzyme Ubp12p. Mol. Cell. 11:2003;927-938.