Neddylation-induced conformational control regulates cullin RING ligase activity in vivo

Journal of Molecular Biology

Volumn 409, Issue 2, 2011, Pages 136-145

  Boh, Boon Kim ^a,b   Smith, Peter G ^c   Hagen, Thilo ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

CAND1; conformational changes; cullin RING ligases; Nedd8; Rbx1

Indexed keywords

CULLIN; CULLIN 1; CULLIN 2; CULLIN RING LIGASE; ENZYME INHIBITOR; MUTANT PROTEIN; NEDD8 PROTEIN; PROTEIN; PROTEIN RBX1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CONFORMATIONAL TRANSITION; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VIVO STUDY; NEDDYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MODIFICATION; UBIQUITINATION;

EID: 79955898446     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.03.023     Document Type: Article

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