Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome

Science

Volumn 292, Issue 5520, 2001, Pages 1382-1385

  Lyapina, Svetlana ^a   Cope, Gregory ^a   Shevchenko, Anna ^b,e   Serino, Giovanna ^c   Tsuge, Tomohiko ^c   Zhou, Chunshui ^d   Wolf, Dieter A ^d   Wei, Ning ^c   Shevchenko, Andrej ^b,e   Deshaies, Raymond J ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c YALE UNIVERSITY   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; PLANTS (BOTANY);

PROTEOLYSIS;

ENZYMES;

COP9 SIGNALOSOME; FUNGAL PROTEIN; NEDD8 PROTEIN; PROTEIN CUL1; PROTEIN P27; PROTEIN SUBUNIT; REGULATOR PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; VEGETABLE PROTEIN; CELL CYCLE PROTEIN; CULLIN; CULLIN 1; HYBRID PROTEIN; MULTIPROTEIN COMPLEX; NEDD8 PROTEIN, HUMAN; NEDD8 PROTEIN, MOUSE; PEPTIDE HYDROLASE; PEPTIDE SYNTHASE; PROTEIN; UBIQUITIN;

ARTICLE; COMPLEX FORMATION; CONJUGATION; HUMAN; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SCHIZOSACCHAROMYCES POMBE; ANIMAL; CELL STRAIN 3T3; CHEMISTRY; ENZYME SPECIFICITY; GENETIC TRANSFECTION; GENETICS; HELA CELL; MASS SPECTROMETRY; METABOLISM; MOUSE; MUTATION; PROTEIN BINDING; PROTEIN PROCESSING; SCHIZOSACCHAROMYCES; SWINE; TWO HYBRID SYSTEM; WESTERN BLOTTING;

SCHIZOSACCHAROMYCES POMBE;

3T3 CELLS; ANIMALS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CULLIN PROTEINS; FUNGAL PROTEINS; HELA CELLS; HUMANS; MASS SPECTROMETRY; MICE; MULTIPROTEIN COMPLEXES; MUTATION; PEPTIDE HYDROLASES; PEPTIDE SYNTHASES; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; PROTEINS; RECOMBINANT FUSION PROTEINS; SCHIZOSACCHAROMYCES; SKP CULLIN F-BOX PROTEIN LIGASES; SUBSTRATE SPECIFICITY; SWINE; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITINS;

EID: 0035906430     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1059780     Document Type: Article

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