Mouse Hepatic Oval Cells Require Met-Dependent PI3K to Impair TGF-β-Induced Oxidative Stress and Apoptosis

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Martínez Palacián, Adoración ^a   del Castillo, Gaelle ^a,c   Suárez Causado, Amileth ^a,d   García Álvaro, María ^a   Morena Frutos, Diego de la ^a   Fernández, Margarita ^a   Roncero, Cesáreo ^a   Fabregat, Isabel ^b   Herrera, Blanca ^a   Sánchez, Aránzazu ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^d UNIVERSIDAD DE CARTAGENA   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BH3 PROTEIN; BIM PROTEIN; CASPASE 3; GLUTATHIONE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BMF; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SCATTER FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE SILENCING; HEPATIC OVAL CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARACRINE SIGNALING; PROTEIN ANALYSIS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL; UPREGULATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL LINE; GLUTATHIONE; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLSERINES; PROTO-ONCOGENE PROTEINS C-MET; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84871802298     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053108     Document Type: Article

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