Role of MAP kinases and their cross-talk in TGF-β1-induced apoptosis in FaO rat hepatoma cell line

Hepatology

Volumn 35, Issue 6, 2002, Pages 1360-1371

  Park, Hyun Jin ^a   Kim, Byung Chul ^b   Kim, Seong Jin ^b   Choi, Kyeong Sook ^a  

^a Ajou University School of Medicine   (South Korea)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOCHROME C OXIDASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; LIVER CELL CARCINOMA; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

EID: 0036614369     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.33205     Document Type: Article

References (49)

1. Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor β1
2. In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor β1
3. The retinoblastoma gene product inhibits TGF-β1 induced apoptosis in primary rat hepatocytes and human Huh-7 hepatoma cells
4. Cdc2 and Cdk2 kinase activated by TGF-β trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells
5. ICE-like protease (caspase) is involved in transforming growth factor-β1-mediated apoptosis in FaO rat hepatoma cell line
6. Mitogen-activated protein kinase pathways
7. Parallel signal processing among mammalian MAPKs
8. How MAP kinases are regulated
9. Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells
10. Release from growth arrest by transforming growth factor beta 1 requires cellular ras activity
11. Transforming growth factor beta 1 inhibits mitogen-activated protein kinase induced by basic fibroblast growth factor in smooth muscle cells
12. Cell type-specific modulation of cell growth by transforming growth factor beta1 does not correlate with mitogen-activated protein kinase activation
13. The involvement of p38 MAPK in transforming growth factor beta1-induced apoptosis in murine hepatocytes
14. Activation of p38MAPK by TGF-beta in fetal rat hepatocytes requires radical oxygen production, but is dispensable for cell death
15. Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum membrane, and mitochondrial membranes
16. Tensin can induce JNK and p38 activation
17. Multiple mitogenactivated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation
18. 2-terminal kinase and p38 kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death
19. 2-terminal protein kinase
20. A novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38α and βMAPKs
21. In situ detection of apoptosis during embryogenesis with annexin V: From whole mount to ultrastructure
22. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
23. PD98059 is a specific inhibitor of the activation of mitogen-activated protein kinase in vitro and in vivo
24. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
25. Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase
26. The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a nonspecific effect upon the ERK pathway
27. The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activated protein kinase
28. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
29. The Bcl-2 family and cell death regulation
30. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
31. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
32. Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase
33. Cardiotrophin (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy
34. Extracellular signal-regulated kinase (ERK) activity is required for TPA-mediated inhibition of drug-induced apoptosis
35. Signal transduction by the JNK group of MAP kinases
36. The p38 signal transduction pathway: Activation and function
37. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation
38. Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis
39. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha
40. TGF-β1-induced apoptosis is mediated by the adaptor Daxx that facilitates JNK activation
41. Mitochondria as the central control point of apoptosis
42. Transforming growth factor-β1 induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a ∼700-kd apoptosome caspase-processing complex
43. Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor β in fetal hepatocytes
44. p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis
45. P38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells
46. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
47. Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes
48. 2-terminal kinase/p38 mitogen-activated protein kinases
49. SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis