Ceramide-induced apoptosis: Role of catalase and hepatocyte growth factor

Free Radical Biology and Medicine

Volumn 37, Issue 2, 2004, Pages 166-175

  Kannan, Ram ^a   Jin, Manlin ^a   Gamulescu, Maria Andreea ^a   Hinton, David R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Apoptosis; Catalase; Ceramide; Free radicals; Hepatocyte growth factor; Mitochondria; Oxidant stress

Indexed keywords

CASPASE 3; CATALASE; CERAMIDE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; SCATTER FACTOR;

APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA CELL; STATISTICAL SIGNIFICANCE;

ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CATALASE; CELL PROLIFERATION; CELLS, CULTURED; CERAMIDES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FREE RADICALS; HEPATOCYTE GROWTH FACTOR; HUMANS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; INTRACELLULAR MEMBRANES; MITOCHONDRIA; OXIDATIVE STRESS; PERMEABILITY; PIGMENT EPITHELIUM OF EYE; REACTIVE OXYGEN SPECIES; RETINA; TIME FACTORS;

EID: 2942590471     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.04.011     Document Type: Article

References (59)

1. Hannun Y.A. The sphingomyelin cycle and the second messenger function of ceramide. J. Biol. Chem. 269:1994;3125-3128
2. Perry D.K. Ceramide and apoptosis. Biochem. Soc. Trans. 27:1999;399-404
3. Obeid L.M., Linardic C.M., Karolak L.A., Hannun Y.A. Programmed cell death induced by ceramide. Science. 259:1993;1769-1771
4. Jayadev S.B., Liu A.E., Lee J.Y., Nazaire F., Pushkareva M.Y., Obeid L.M., Hannun Y.A. Role of ceramide in cell cycle arrest. J. Biol. Chem. 270:1995;2047-2052
5. Spiegel S., Merrill A.H. Jr. Sphingolipid metabolism and growth retardation. FASEB J. 10:1996;1388-1397
6. Schutze S., Potthoff K., Machleidt T., Berkovic D., Wiegmann K., Kronke M. TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell. 71:1992;756-776
7. Wiegmann K., Schutze S., Machleidt T., Witte D., Kronke M. Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell. 78:1994;1005-1015
8. Ruvolo P.P. Intracellular signal transduction pathways activated by ceramide and its metabolites. Pharm. Res. 47:2003;383-392
9. Kajimoto T., Shirai Y., Sakai N., Yamamoto T., Matzuzaki H., Kikkawa U., Saito N. Ceramide-induced apoptosis by translocation, phosphorylation and activation of protein kinase Cdelta at Golgi complex. J. Biol. Chem. 279:2004;12668-12676
10. Mansat-de Mas V., Bezombes C., Quillet-Mary A., Bettaieb A., D'Orgeix A.D., Laurent G., Jeffrezou J.P. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. Mol. Pharmacol. 56:1999;867-874
11. Cabrero A., Algret M., Sanchez R.M., Adzet T., Laguna J.C., Carrera M.V. Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells. J. Biol. Chem. 277:2002;10100-10107
12. Pedersen J.Z., Marcocci L., Rossi L., Mavelli I., Rotilio G. Generation of daunomycin radicals on the outer side of the erythrocyte membrane. Biochem. Biophys. Res. Commun. 168:1990;240-247
13. Wang J.H., Redmond H.P., Watson R.W., Bouchier Hayes D. Induction of human endothelial cell apoptosis requires both heat shock and oxidative stress responses. Am. J. Physiol. 272:1997;C1543-C1551
14. Kondo T., Matsuda T., Tashima M., Umehara H., Domae N., Yokoyama K., Uchiyama T., Okazaki T. Suppression of heat shock protein-70 by ceramide in heat shock induced HL-60 cell apoptosis. J. Biol. Chem. 275:2000;8872-8879
15. Kondo T., Matsuda T., Kitano T., Takahashi A., Tashima M., Ishikura H., Umehara H., Domae N., Uchiyama T., Okazaki T. Role of c-jun expression increased by heat-shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis. J. Biol. Chem. 275:2000;7668-7676
16. Lavrentiadou S.N., Chan C., Kawcak T., Ravid T., Tsaba A., van der Vliet A., Rasooly R., Goldkorn T. Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. Am. J. Respir. Cell. Mol. Biol. 25:2001;676-684
17. Garcia-Ruiz C., Colell A., Mari M., Morales A., Fernandez-Checa J.C. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species: role of mitochondrial glutathione. J. Biol. Chem. 272:1997;11367-11369
18. Dunaief J.L., Dentchev T., Ying G.S., Milam A.H. The role of apoptosis in age-related macular degeneration. Arch. Ophthalmol. 120:2002;1435-1442
19. Hisatomi T., Sakamoto T., Goto Y., Yamanaka I., Oshima Y., Hata Y., Ishibashi T., Inomata H., Susin S.A., Kroemer G. Critical role of photoreceptor apoptosis in functional damage after retinal attachment. Curr. Eye Res. 24:2002;161-172
20. Jones S.E., Jomary C., Grist J., Stewart H.J., Neal M.J. Altered expression of secreted frizzled-related protein-2 in retinitis pigmentosa retinas. Invest. Ophthalmol. Visual Sci. 41:2000;1297-1301
21. Quillet-Mary A., Jaffrezou J.P., Mansat V., Bordier C., Naval J., Laurent J.P. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J. Biol. Chem. 272:1997;21388-21395
22. Chan C., Goldkorn T. Ceramide path in human lung cell death. Am. J. Respir. Cell. Mol. Biol. 22:2000;460-468
23. Sheu S.-J., Wu S.-N. Mechanism of inhibitory actions of oxidizing agents on calcium-activated potassium current in cultured pigment epithelial cells of the human retina. Invest. Ophthalmol. Visual Sci. 44:2003;1237-1244
24. Barak A., Morse L.S., Goldkorn T. Ceramide: a potential mediator of apoptosis in human retinal pigment epithelial cells. Invest. Ophthalmol. Visual Sci. 42:2001;247-254
25. Hinton D.R., He S., Lopez P.F. Apoptosis in surgically excised choroidal neovascularization in age-related macular degeneration. Arch. Ophthalmol. 116:1998;203-209
26. Acharya U., Patel S., Koundakjian E., Nagashima K., Han X., Acharya J.K. Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration. Science. 14:2003;1740-1743
27. Yuson M., Marfany G., Gonzalez-Duarte R. Mutation of CERKL, a novel human ceramide kinase gene, causes autosomal recessive retinitis pigmentosa (RP26). Am. J. Hum. Genet. 74:2004;128-138
28. Matsumoto K., Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J. Biochem. (Tokyo). 119:1996;591-600
29. He P.M., He S., Garner J.A., Ryan S.J., Hinton D.R. Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor. Biochem. Biophys. Res. Commun. 249:1998;253-257
30. Jin M.L., Chen Y., He S., Ryan S.J., Hinton D.R. Hepatocyte growth factor and its role in the pathogenesis of retinal detachment. Invest. Ophthalmol. Visual Sci. 45:2004;323-329
31. Morita M., Watanabe Y., Akaike T. Protective effect of hepatocyte growth factor on interferon-gamma-induced cytotoxicity in mouse hepatocytes. Hepatology. 21:1995;1585-1593
32. Hiscox S., Jiang W.G. Hepatocyte growth factor/scatter factor disrupts epithelial tumour cell-cell adhesion: involvement of beta catenin. Anticancer Res. 19:1999;509-517
33. Yuan R.-Q., Fan S., Achary M., Stewart D.M., Goldberg I.D., Rosen E.M. Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor in the setting of DNA damage. Cancer Res. 61:2001;8022-8031
34. Fan S., Wang J.-A., Yuan R.-Q., Rockwell S., Andres J., Zlatapolsky A., Goldberg D., Rosen E.M. Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents. Oncogene. 17:1998;131-141
35. Gao M., Fan S., Goldberg I.D., Laterra J., Kitsis R.N., Rosen E.M. Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells. J. Biol. Chem. 276:2001;47257-47265
36. Arakaki N., Kajihara T., Arakaki R., Ohnishi T., Kazi J.A., Nakashima H., Daikuhara Y. Involvement of oxidative stress in tumor cytotoxic activity of hepatocyte growth factor/scatter factor. J. Biol. Chem. 274:1999;13541-13546
37. Zhang C., Baffi J., Cousins S.W., Csaky K.G. Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor. J. Cell Sci. 116:2003;1915-1923
38. Jin M.L., He S., Worpel V., Ryan S.J., Hinton D.R. Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha. Invest. Ophthalmol. Visual Sci. 41:2000;4324-4332
39. Merril A.H., Wang E., Gilchrist D.G., Riley R.T. Fumonisins and other inhibitors of de novo sphingolipid biosynthesis. Adv. Lipid Res. 26:1993;215-234
40. Brenne B., Ferlinz K., Grassme H., Weller M., Koppenhoefer U., Dichgans J., Sandhoff K., Lang F., Gulbins E. Fas/CD95/Apo-1 activates the acidic sphingomyelinase via caspases. Cell Death Differ. 5:1998;29-37
41. Pascual M., Valles S.Y., Renau-Piqueras J., Guerri C. Ceramide pathways modulate ethanol-induced cell death in astrocytes. J. Neurochem. 87:2003;1535-1545
42. Cai J., Chen Y., Seth S., Furukawa S., Compans R.W., Jones D.P. Inhibition of influenza infection by glutathione. Free Radic. Biol. Med. 34:2003;928-936
43. Wang G.-W., Klein J.B., Kang Y.J. Metallothionein inhibits doxorubicin-induced mitochondrial cytochrome c release and caspase-3 activation in cardiomyocytes. J. Pharmacol. Exp. Ther. 298:2001;462-468
44. Iwai K., Kondo T., Watanabe M., Yabu T., Kitano T., Taguchi Y., Umehara H., Takahashi A., Uchiyama T., Okazaki T. Ceramide increases oxidative damage due to inhibition of caspase-3-dependent proteolysis in HL-60 cell apoptosis. J. Biol. Chem. 278:2003;9813-9822
45. Shabbits J.A., Mayer L.D. Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro. Biochim. Biophys. Acta. 1612:2003;98-106
46. Andrieu-Abadie N., Gouaze V., Salvayre R., Lvade T. Ceramide in apoptosis signaling: relationship with oxidative stress. Free Radic. Biol. Med. 31:2001;717-728
47. Takeda Y., Tashima M., Takahashi A., Uchiyama T., Okazaki T. Ceramide generation in nitric oxide-induced apoptosis: activation of magnesium-dependent neutral sphingomyelinase via caspase-3. J. Biol. Chem. 274:1999;10654-10660
48. Matsura T., Kai M., Fujii Y., Ito H., Yamada K. Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation. Free Radic. Res. 30:1999;73-83
49. Movsesyan V.A., Yakovlev A.G., Dabaghyan E.A., Stoica B.A., Faden A.I. Ceramide induces neuronal apoptosis through the caspase-9/caspase-3 pathway. Biochem. Biophys. Res. Commun. 299:2002;201-207
50. Kroemer G., Dallaporta B., Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60:1998;619-642
51. Susin S.A., Zamzami N., Kroemer G. Mitochondria as regulators of apoptosis: doubt no more. Biochim. Biophys. Acta. 1366:1998;151-166
52. Leist M., Jaatela M. Four deaths and a funeral: from caspases to alternate mechanisms. Nat. Rev. Cell Biol. 2:2001;589-598
53. Pryor W.A. Oxyradicals and related species: their formation, lifetimes and reactions. Annu. Rev. Physiol. 60:1986;619-642
54. Phillips D.C., Griffiths H.R. Ceramide induces a loss in cytosolic peroxide levels in mononuclear cells. Biochem. J. 375:2003;567-579
55. Tommasini I., Sestili P., Cantoni O. Delayed formation of hydrogen peroxide mediates the lethal response evoked by peroxynitrite in U937 cells. Mol. Pharmacol. 61:2002;870-878
56. Reid M.B., Haack K.E., Franchek K.M., Valberg P.A., Kobzik L., West M.S. Reactive oxygen in skeletal muscle. I. Intracellular oxidant kinetics and fatigue in vitro. J. Appl. Physiol. 73:1992;1797-1804
57. El-Assaad W., Kozhaya L., Araysi S., Panjarian S., Bitar F.F., Baz E., El-Sabban M.E., Dbaibi G.S. Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukemic cells. Biochem. J. 376:2003;725-732
58. Chen Y., Cai J., Murphy T.J., Jones D.P. Overexpressed human mitochondrial thioredoxin confers resistance to oxidant induced apoptosis in human osteosarcoma cells. J. Biol. Chem. 277:2002;33242-33248
59. Shimada T., Hiraishi H., Terano A. Hepatocyte growth factor protects gastric epithelial cells against ceramide-induced apoptosis through induction of cyclooxygenase-2. Life Sci. 68:2000;539-546