Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds

ACS Chemical Neuroscience

Volumn 3, Issue 12, 2012, Pages 1050-1062

  Luedtke, Robert R ^a   Mishra, Yogesh ^a   Wang, Qi ^b   Griffin, Suzy A ^a   Bell Horner, Cathy ^a   Taylor, Michelle ^a   Vangveravong, Suwanna ^b   Dillon, Glenn H ^a   Huang, Ren Qi ^a   Reichert, David E ^b   MacH, Robert H ^b  

^a University of North   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

binding selectivity; D2 like dopamine receptors; Dopamine receptors; functional selectivity; GPCR model building; GPCR structure; ligand receptor docking

Indexed keywords

1 [(5 METHOXY 1H INDOL 3 YL)METHYL] 4 [4 (METHYLTHIO)PHENYL]PIPERIDIN 4 OL; 7 [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTOXY] 3,4 DIHYDROQUINOLIN 2(1H) ONE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; HALOPERIDOL; QUINPIROLE; SV 293; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; PRIORITY JOURNAL; PROTEIN FUNCTION;

DOPAMINE ANTAGONISTS; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

RUMEX;

EID: 84871298407     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn300142q     Document Type: Article

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