Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D 3 receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 1, 2005, Pages 77-87

  Chu, Wenhua ^a   Tu, Zhude ^a   McElveen, Elizabeth ^a   Xu, Jinbin ^a   Taylor, Michelle ^a   Luedtke, Robert R ^a   MacH, Robert H ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Atypical antipsychotics; Dopamine D 3 receptors

Indexed keywords

1H INDOL 2 CARBOXYLIC ACID[4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL]AMIDE; 4 DIMETHYLAMINO N [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL]BENZAMIDE; BENZOFURAN 2 CARBOXYLIC ACID[4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL]AMIDE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR STIMULATING AGENT; DOPAMINE 4 RECEPTOR; LIGAND; N [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL] 4 METHYLSULFANYLBENZAMIDE; PHENYL GROUP; PIPERAZINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 3 RECEPTOR; SEROTONIN 4 RECEPTOR; SEROTONIN 5 RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR; TRACER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CORRELATION ANALYSIS; DOPAMINERGIC SYSTEM; DRUG BINDING; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR PROBE; POSITRON EMISSION TOMOGRAPHY; STRUCTURE ANALYSIS;

ADENYLATE CYCLASE; CELL LINE; DOPAMINE AGENTS; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; PIPERAZINES; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; RECEPTORS, SIGMA;

EID: 9644291553     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.09.054     Document Type: Article

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