Sulforaphane Induces Cell Cycle Arrest and Apoptosis in Acute Lymphoblastic Leukemia Cells

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Suppipat, Koramit ^a   Park, Chun Shik ^b   Shen, Ye ^b   Zhu, Xiao ^b   Lacorazza, H Daniel ^b  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; PROTEIN P53; SULFORAPHANE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER MODEL; CANCER PATIENT; CELL CYCLE ARREST; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL LINE; LYMPHOBLAST; M PHASE CELL CYCLE CHECKPOINT; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; HUMANS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; THIOCYANATES;

EID: 84871203808     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051251     Document Type: Article

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