p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.

Cancer chemotherapy and pharmacology

Volumn 57, Issue 3, 2006, Pages 317-327

  Shen, Guoxiang ^a   Xu, Changjiang ^a   Chen, Chi ^a   Hebbar, Vidya ^a   Kong, Ah Ng Tony ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; SULFORAFAN; TETRAZOLIUM; THIOCYANIC ACID DERIVATIVE;

ARTICLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL STRAIN HT29; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; UPREGULATION; WESTERN BLOTTING;

ACETYLCYSTEINE; ANTICARCINOGENIC AGENTS; BLOTTING, WESTERN; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; G1 PHASE; GENE EXPRESSION; GLUTATHIONE; HT29 CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRAZOLIUM SALTS; THIOCYANATES; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 33644841610     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-0050-3     Document Type: Article

References (0)