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Volumn 229, Issue 2, 2013, Pages 232-241

Oxidative stress and myocardial injury in the diabetic heart

Author keywords

cell signalling; diabetes mellitus; glycobiology; ischaemia reperfusion; mitochondrial permeability transition; myocardial injury; oxidative stress

Indexed keywords

ANTIOXIDANT; FREE RADICAL; GLUCOSE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE;

EID: 84871092804     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4113     Document Type: Review
Times cited : (209)

References (120)
  • 1
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2011 update: A report from the American Heart Association
    • Roger VL, Roger VL, Go AS, et al,. Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation 2011; 123: 1-195.
    • (2011) Circulation , vol.123 , pp. 1-195
    • Roger, V.L.1    Roger, V.L.2    Go, A.S.3
  • 2
    • 33947497439 scopus 로고    scopus 로고
    • The diabetic disadvantage: Historical outcomes measures in diabetic patients undergoing cardiac surgery-The pre-intravenous insulin era
    • DOI 10.1053/j.semtcvs.2006.04.004, PII S1043067906000153, Diabetes, Hyperglycemia, and Cardiac Surgery Patient
    • Brown JR, Brown JR, Edwards FH, et al,. The diabetic disadvantage: historical outcomes measures in diabetic patients undergoing cardiac surgery-the pre-intravenous insulin era. Semin Thorac Cardiovasc Surg 2006; 18: 281-288. (Pubitemid 46464508)
    • (2006) Seminars in Thoracic and Cardiovascular Surgery , vol.18 , Issue.4 , pp. 281-288
    • Brown, J.R.1    Edwards, F.H.2    O'Connor, G.T.3    Ross, C.S.4    Furnary, A.P.5
  • 3
    • 79955108012 scopus 로고    scopus 로고
    • Factors influencing the outcomes of patients with both coronary artery disease and diabetes enrolled in standard cardiac rehabilitation programs: A literature review
    • Miketic JK, Miketic JK, Hravnak M, et al,. Factors influencing the outcomes of patients with both coronary artery disease and diabetes enrolled in standard cardiac rehabilitation programs: a literature review. J Cardiovasc Nursing 2011; 26: 210-217.
    • (2011) J Cardiovasc Nursing , vol.26 , pp. 210-217
    • Miketic, J.K.1    Miketic, J.K.2    Hravnak, M.3
  • 4
    • 0030805004 scopus 로고    scopus 로고
    • Heart abnormalities in IDDM
    • DOI 10.1007/s001250051427
    • Fisher BM, Fisher BM,. Heart abnormalities in IDDM. Diabetologia 1997; 40 (suppl 2): S127-129. (Pubitemid 27306940)
    • (1997) Diabetologia , vol.40 , Issue.SUPPL. 2
    • Fisher, B.M.1
  • 6
    • 33644876570 scopus 로고    scopus 로고
    • Clinical outcomes and left ventricular function in diabetic patients with acute myocardial infarction treated by primary coronary angioplasty
    • Katayama T, Katayama T, Nakashima H, et al,. Clinical outcomes and left ventricular function in diabetic patients with acute myocardial infarction treated by primary coronary angioplasty. Int Heart J 2005; 46: 607-618.
    • (2005) Int Heart J , vol.46 , pp. 607-618
    • Katayama, T.1    Katayama, T.2    Nakashima, H.3
  • 7
    • 84859265129 scopus 로고    scopus 로고
    • Diabetes mellitus, myocardial reperfusion, and outcome in patients with acute ST-elevation myocardial infarction treated with primary angioplasty (from HORIZONS AMI)
    • Brener SJ, Mehran R, Dressler O, et al,. Diabetes mellitus, myocardial reperfusion, and outcome in patients with acute ST-elevation myocardial infarction treated with primary angioplasty (from HORIZONS AMI). Am J Cardiol 2012; 109: 1111-1116.
    • (2012) Am J Cardiol , vol.109 , pp. 1111-1116
    • Brener, S.J.1    Mehran, R.2    Dressler, O.3
  • 9
    • 0031984182 scopus 로고    scopus 로고
    • Comparison of factors associated with 30-day mortality after coronary artery bypass grafting in patients with versus without diabetes mellitus
    • DOI 10.1016/S0002-9149(97)00797-2, PII S0002914997007972
    • Cohen Y, Cohen Y, Raz I, et al,. Comparison of factors associated with 30-day mortality after coronary artery bypass grafting in patients with versus without diabetes mellitus. Israeli Coronary Artery Bypass (ISCAB) Study Consortium. Am J Cardiol 1998; 81: 7-11. (Pubitemid 28046833)
    • (1998) American Journal of Cardiology , vol.81 , Issue.1 , pp. 7-11
    • Cohen, Y.1    Raz, I.2    Merin, G.3    Mozes, B.4
  • 10
    • 0141451698 scopus 로고    scopus 로고
    • Coronary artery bypass grafting in type II diabetic patients: A comparison between insulin-dependent and non-insulin-dependent patients at short- and mid-term follow-up
    • DOI 10.1016/S0003-4975(03)00838-5, PII S0003497503008385
    • Luciani N, Luciani N, Nasso G, et al,. Coronary artery bypass grafting in type II diabetic patients: a comparison between insulin-dependent and non-insulin-dependent patients at short- and mid-term follow-up. Ann Thorac Surg 2003; 76: 1149-1154. (Pubitemid 37204724)
    • (2003) Annals of Thoracic Surgery , vol.76 , Issue.4 , pp. 1149-1154
    • Luciani, N.1    Nasso, G.2    Gaudino, M.3    Abbate, A.4    Glieca, F.5    Alessandrini, F.6    Girola, F.7    Santarelli, F.8    Possati, G.9
  • 11
    • 0036711776 scopus 로고    scopus 로고
    • Early postoperative outcome and medium-term survival in 540 diabetic and 2239 nondiabetic patients undergoing coronary artery bypass grafting
    • DOI 10.1016/S0003-4975(02)03778-5, PII S0003497502037785
    • Szabó Z, Szabó Z, Håkanson E, et al,. Early postoperative outcome and medium-term survival in 540 diabetic and 2239 nondiabetic patients undergoing coronary artery bypass grafting. Ann Thorac Surg 2002; 74: 712-719. (Pubitemid 35001797)
    • (2002) Annals of Thoracic Surgery , vol.74 , Issue.3 , pp. 712-719
    • Szabo, Z.1    Hakanson, E.2    Svedjeholm, R.3
  • 12
    • 70350445742 scopus 로고    scopus 로고
    • Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart
    • Anderson EJ, Anderson EJ, Kypson AP, et al,. Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 2009; 54: 1891-1898.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1891-1898
    • Anderson, E.J.1    Anderson, E.J.2    Kypson, A.P.3
  • 13
    • 84856491833 scopus 로고    scopus 로고
    • The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion
    • Raedschelders K, Ansley DM, Chen DDY,. The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion. Pharmacol Ther 2012; 133: 230-255.
    • (2012) Pharmacol Ther , vol.133 , pp. 230-255
    • Raedschelders, K.1    Ansley, D.M.2    Chen, D.D.Y.3
  • 15
    • 77956572071 scopus 로고    scopus 로고
    • Mitochondria in the diabetic heart
    • Bugger H, Abel ED,. Mitochondria in the diabetic heart. Cardiovasc Res 2010; 88: 229-240.
    • (2010) Cardiovasc Res , vol.88 , pp. 229-240
    • Bugger, H.1    Abel, E.D.2
  • 16
    • 84860786577 scopus 로고    scopus 로고
    • Free radical biology of the cardiovascular system
    • Chen AF, Chen D-D, Daiber A, et al,. Free radical biology of the cardiovascular system. Clin Sci 2012; 123: 73-91.
    • (2012) Clin Sci , vol.123 , pp. 73-91
    • Chen, A.F.1    Chen, D.2    Daiber, A.3
  • 17
    • 0027461348 scopus 로고
    • Direct detection of endogenous hydroxyl radical production in cultured adult cardiomyocytes during anoxia and reoxygenation: Is the hydroxyl radical really the most damaging radical species?
    • Khalid MA, Ashraf M,. Direct detection of endogenous hydroxyl radical production in cultured adult cardiomyocytes during anoxia and reoxygenation. Is the hydroxyl radical really the most damaging radical species? Circ Res 1993; 72: 725-736. (Pubitemid 23077763)
    • (1993) Circulation Research , vol.72 , Issue.4 , pp. 725-736
    • Khalid, M.A.1    Ashraf, M.2
  • 18
    • 0037291356 scopus 로고    scopus 로고
    • Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats
    • DOI 10.1016/S0047-6374(02)00185-9, PII S0047637402001859
    • Tanguy S, de Leiris J, Besse S, et al,. Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats. Mech Ageing Dev 2003; 124: 229-235. (Pubitemid 36293932)
    • (2003) Mechanisms of Ageing and Development , vol.124 , Issue.2 , pp. 229-235
    • Tanguy, S.1    De Leiris, J.2    Besse, S.3    Boucher, F.4
  • 19
    • 34548746306 scopus 로고    scopus 로고
    • Myocardial reperfusion injury
    • Yellon DM, Hausenloy DJ,. Myocardial reperfusion injury. N Engl J Med 2007; 357: 1121-1135.
    • (2007) N Engl J Med , vol.357 , pp. 1121-1135
    • Yellon, D.M.1    Hausenloy, D.J.2
  • 20
    • 0034596947 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS)-induced ROS release: A new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
    • Zorov DB, Zorov DB, Filburn CR, et al,. Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med 2000; 192: 1001-1014.
    • (2000) J Exp Med , vol.192 , pp. 1001-1014
    • Zorov, D.B.1    Zorov, D.B.2    Filburn, C.R.3
  • 21
    • 33745684904 scopus 로고    scopus 로고
    • Mitochondrial ROS-induced ROS release: An update and review
    • Zorov DB, Zorov DB, Juhaszova M, et al,. Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta 2006; 1757: 509-517.
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 509-517
    • Zorov, D.B.1    Zorov, D.B.2    Juhaszova, M.3
  • 22
    • 0035951823 scopus 로고    scopus 로고
    • + and is a causative event in the death of myocytes in postischemic reperfusion of the heart
    • + and is a causative event in the death of myocytes in postischemic reperfusion of the heart. J Biol Chem 2001; 276: 2571-2575.
    • (2001) J Biol Chem , vol.276 , pp. 2571-2575
    • Lisa, F.1    Lisa, F.2    Menabò, R.3
  • 24
    • 1142273368 scopus 로고    scopus 로고
    • Mitochondrial permeability transition pore opening during myocardial reperfusion - A target for cardioprotection
    • DOI 10.1016/S0008-6363(03)00533-9
    • Halestrap AP, Halestrap AP, Clarke SJ, et al,. Mitochondrial permeability transition pore opening during myocardial reperfusion-a target for cardioprotection. Cardiovasc Res 2004; 61: 372-385. (Pubitemid 38210145)
    • (2004) Cardiovascular Research , vol.61 , Issue.3 , pp. 372-385
    • Halestrap, A.P.1    Clarke, S.J.2    Javadov, S.A.3
  • 25
    • 0037427440 scopus 로고    scopus 로고
    • Mitochondrial permeability transition: A common pathway to necrosis and apoptosis
    • DOI 10.1016/S0006-291X(03)00618-1
    • Kim J, Kim J, He L, et al,. Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem Biophys Res Commun 2003; 304: 463-470. (Pubitemid 36506518)
    • (2003) Biochemical and Biophysical Research Communications , vol.304 , Issue.3 , pp. 463-470
    • Kim, J.-S.1    He, L.2    Lemasters, J.J.3
  • 26
    • 34547130863 scopus 로고    scopus 로고
    • The role of mitochondria in protection of the heart by preconditioning
    • DOI 10.1016/j.bbabio.2007.05.008, PII S0005272807001132
    • Halestrap AP, Halestrap AP, Clarke SJ, et al,. The role of mitochondria in protection of the heart by preconditioning. Biochim Biophys Acta 2007; 1767: 1007-1031. (Pubitemid 47101788)
    • (2007) Biochimica et Biophysica Acta - Bioenergetics , vol.1767 , Issue.8 , pp. 1007-1031
    • Halestrap, A.P.1    Clarke, S.J.2    Khaliulin, I.3
  • 27
    • 33846443957 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in cardiac cell injury and death
    • DOI 10.1007/s10557-006-0642-0
    • Honda HM, Honda HM, Ping P, et al,. Mitochondrial permeability transition in cardiac cell injury and death. Cardiovasc Drugs Ther 2006; 20: 425-432. (Pubitemid 46144219)
    • (2006) Cardiovascular Drugs and Therapy , vol.20 , Issue.6 , pp. 425-432
    • Honda, H.M.1    Ping, P.2
  • 28
    • 38849156952 scopus 로고    scopus 로고
    • Heart mitochondria: Gates of life and death
    • DOI 10.1093/cvr/cvm005
    • Gustafsson AB, Gustafsson AB, Gottlieb RA, et al,. Heart mitochondria: gates of life and death. Cardiovasc Res 2008; 77: 334-343. (Pubitemid 351197632)
    • (2008) Cardiovascular Research , vol.77 , Issue.2 , pp. 334-343
    • Gustafsson, A.B.1    Gottlieb, R.A.2
  • 29
    • 4043087772 scopus 로고    scopus 로고
    • Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection
    • DOI 10.1161/01.CIR.0000126294.81407.7D
    • Hausenloy D, Hausenloy D, Wynne A, et al,. Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. Circulation 2004; 109: 1714-1717. (Pubitemid 38500671)
    • (2004) Circulation , vol.109 , Issue.14 , pp. 1714-1717
    • Hausenloy, D.1    Wynne, A.2    Duchen, M.3    Yellon, D.4
  • 30
    • 67649882599 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3β in cardioprotection
    • Juhaszova M, Juhaszova M, Zorov DB, et al,. Role of glycogen synthase kinase-3β in cardioprotection. Circ Res 2009; 104: 1240-1252.
    • (2009) Circ Res , vol.104 , pp. 1240-1252
    • Juhaszova, M.1    Juhaszova, M.2    Zorov, D.B.3
  • 33
    • 0031407680 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes
    • Qian T, Qian T, Nieminen AL, et al,. Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes. Am J Physiol 1997; 273: C1783-1792.
    • (1997) Am J Physiol , vol.273
    • Qian, T.1    Qian, T.2    Nieminen, A.L.3
  • 34
    • 57649219323 scopus 로고    scopus 로고
    • The role of external and matrix pH in mitochondrial reactive oxygen species generation
    • Selivanov VA, Selivanov VA, Zeak JA, et al,. The role of external and matrix pH in mitochondrial reactive oxygen species generation. J Biol Chem 2008; 283: 29292-29300.
    • (2008) J Biol Chem , vol.283 , pp. 29292-29300
    • Selivanov, V.A.1    Selivanov, V.A.2    Zeak, J.A.3
  • 35
    • 55249085659 scopus 로고    scopus 로고
    • Comorbidity in patients undergoing coronary artery bypass graft surgery: Impact on outcome and implications for cardiac rehabilitation
    • Scrutinio D, Scrutinio D, Giannuzzi P, et al,. Comorbidity in patients undergoing coronary artery bypass graft surgery: impact on outcome and implications for cardiac rehabilitation. Eur J Cardiovasc Prevent Rehab 2008; 15: 379-385.
    • (2008) Eur J Cardiovasc Prevent Rehab , vol.15 , pp. 379-385
    • Scrutinio, D.1    Scrutinio, D.2    Giannuzzi, P.3
  • 36
    • 0030977837 scopus 로고    scopus 로고
    • The diabetic heart is more sensitive to ischemic injury
    • DOI 10.1016/S0008-6363(97)00018-7, PII S0008636397000187
    • Paulson DJ,. The diabetic heart is more sensitive to ischemic injury. Cardiovasc Res 1997; 34: 104-112. (Pubitemid 27261918)
    • (1997) Cardiovascular Research , vol.34 , Issue.1 , pp. 104-112
    • Paulson, D.J.1
  • 38
    • 80755153640 scopus 로고    scopus 로고
    • Healing the diabetic heart: Does myocardial preconditioning work?
    • Balakumar P, Sharma NK,. Healing the diabetic heart: does myocardial preconditioning work? Cell Signal 2011; 24: 53-59.
    • (2011) Cell Signal , vol.24 , pp. 53-59
    • Balakumar, P.1    Sharma, N.K.2
  • 40
    • 80053515769 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: Avenues for a mechanistic-based therapeutic approach
    • Folli F, Corradi D, Fanti P, et al,. The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach. Curr Diabetes Rev 2011; 7: 313-324.
    • (2011) Curr Diabetes Rev , vol.7 , pp. 313-324
    • Folli, F.1    Corradi, D.2    Fanti, P.3
  • 41
    • 69249112283 scopus 로고    scopus 로고
    • Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice
    • Yokota T, Kinugawa S, Hirabayashi K, et al,. Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice. Am J Physiol Heart Circ Physiol 2009; 297: H1069-1077.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Yokota, T.1    Kinugawa, S.2    Hirabayashi, K.3
  • 42
    • 39049099427 scopus 로고    scopus 로고
    • Oxidative stress in non-insulin-dependent diabetes mellitus (NIDDM) patients
    • DOI 10.1007/s00592-007-0018-3
    • Ramakrishna V, Jailkhani R,. Oxidative stress in non-insulin-dependent diabetes mellitus (NIDDM) patients. Acta Diabetol 2008; 45: 41-46. (Pubitemid 351238275)
    • (2008) Acta Diabetologica , vol.45 , Issue.1 , pp. 41-46
    • Ramakrishna, V.1    Jailkhani, R.2
  • 43
    • 79955869166 scopus 로고    scopus 로고
    • Differences in myocardial PTEN expression and Akt signalling in type 2 diabetic and nondiabetic patients undergoing coronary bypass surgery
    • Wang B, Wang B, Raedschelders K, et al,. Differences in myocardial PTEN expression and Akt signalling in type 2 diabetic and nondiabetic patients undergoing coronary bypass surgery. Clin Endocrinol 2011; 74: 705-713.
    • (2011) Clin Endocrinol , vol.74 , pp. 705-713
    • Wang, B.1    Wang, B.2    Raedschelders, K.3
  • 45
    • 34248369249 scopus 로고    scopus 로고
    • The use of vitamin E in type 2 diabetes mellitus
    • DOI 10.1080/10641960701361601, PII 778454840
    • Fardoun RZ,. The use of vitamin E in type 2 diabetes mellitus. Clin Exp Hypertens 2007; 29: 135-148. (Pubitemid 46744123)
    • (2007) Clinical and Experimental Hypertension , vol.29 , Issue.3 , pp. 135-148
    • Fardoun, R.Z.1
  • 46
    • 33645765312 scopus 로고    scopus 로고
    • Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
    • Rolo AP, Palmeira CM,. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol 2006; 212: 167-178.
    • (2006) Toxicol Appl Pharmacol , vol.212 , pp. 167-178
    • Rolo, A.P.1    Palmeira, C.M.2
  • 47
    • 67349249847 scopus 로고    scopus 로고
    • Type 2 diabetes, mitochondrial biology and the heart
    • Sack MN,. Type 2 diabetes, mitochondrial biology and the heart. J Mol Cell Cardiol 2009; 46: 842-849.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 842-849
    • Sack, M.N.1
  • 48
    • 0033857531 scopus 로고    scopus 로고
    • The missing link: A single unifying mechanism for diabetic complications
    • Nishikawa T, Nishikawa T, Edelstein D, et al,. The missing link: a single unifying mechanism for diabetic complications. Kidney Int Suppl 2000; 77: S26-30.
    • (2000) Kidney Int Suppl , vol.77
    • Nishikawa, T.1    Nishikawa, T.2    Edelstein, D.3
  • 50
    • 67650083125 scopus 로고    scopus 로고
    • Increased myocardial NAD(P)H oxidase-derived superoxide causes the exacerbation of postinfarct heart failure in type 2 diabetes
    • Matsushima S, Kinugawa S, Yokota T, et al,. Increased myocardial NAD(P)H oxidase-derived superoxide causes the exacerbation of postinfarct heart failure in type 2 diabetes. Am J Physiol Heart Circ Physiol 2009; 297: H409-416.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Matsushima, S.1    Kinugawa, S.2    Yokota, T.3
  • 52
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • DOI 10.1161/01.CIR.0000012748.58444.08
    • Guzik TJ, Mussa S, Gastaldi D, et al,. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 2002; 105: 1656-1662. (Pubitemid 34298608)
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 53
    • 78650751290 scopus 로고    scopus 로고
    • Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus
    • Takayanagi R, Inoguchi T, Ohnaka K,. Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus. J Clin Biochem Nutr 2011; 48: 72-77.
    • (2011) J Clin Biochem Nutr , vol.48 , pp. 72-77
    • Takayanagi, R.1    Inoguchi, T.2    Ohnaka, K.3
  • 54
    • 80052757568 scopus 로고    scopus 로고
    • Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart
    • Okazaki T, Otani H, Shimazu T, et al,. Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart. Free Rad Res 2011; 45: 1173-1183.
    • (2011) Free Rad Res , vol.45 , pp. 1173-1183
    • Okazaki, T.1    Otani, H.2    Shimazu, T.3
  • 55
    • 84856248012 scopus 로고    scopus 로고
    • Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes
    • Maalouf RM, Eid AA, Gorin YC, et al,. Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes. Am J Physiol Cell Physiol 2012; 302: C597-604.
    • (2012) Am J Physiol Cell Physiol , vol.302
    • Maalouf, R.M.1    Eid, A.A.2    Gorin, Y.C.3
  • 56
    • 79551582218 scopus 로고    scopus 로고
    • Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart
    • Okazaki T, Otani H, Shimazu T, et al,. Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart. J Mol Cell Cardiol 2011; 50: 534-544.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 534-544
    • Okazaki, T.1    Otani, H.2    Shimazu, T.3
  • 57
    • 77950915621 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiovascular disorders: Roles of mitochondria and NADPH oxidase
    • Shen GX,. Oxidative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase. Can J Physiol Pharmacol 2010; 88: 241-248.
    • (2010) Can J Physiol Pharmacol , vol.88 , pp. 241-248
    • Shen, G.X.1
  • 58
    • 0023259759 scopus 로고
    • Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes
    • Wolff SP, Wolff SP, Dean RT, et al,. Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes. Biochem J 1987; 245: 243-250. (Pubitemid 17089839)
    • (1987) Biochemical Journal , vol.245 , Issue.1 , pp. 243-250
    • Wolff, S.P.1    Dean, R.T.2
  • 59
    • 0031421246 scopus 로고    scopus 로고
    • Glycation, oxidation, and lipoxidation in the development of diabetic complications
    • Kennedy AL, Kennedy AL, Lyons TJ, et al,. Glycation, oxidation, and lipoxidation in the development of diabetic complications. Metab Clin Exp 1997; 46: 14-21.
    • (1997) Metab Clin Exp , vol.46 , pp. 14-21
    • Kennedy, A.L.1    Kennedy, A.L.2    Lyons, T.J.3
  • 62
    • 0026777243 scopus 로고
    • Increased glycated Cu,Zn-superoxide dismutase levels in erythrocytes of patients with insulin-dependent diabetis mellitus
    • Kawamura N, Kawamura N, Ookawara T, et al,. Increased glycated Cu,Zn-superoxide dismutase levels in erythrocytes of patients with insulin-dependent diabetis mellitus. J Clin Endocrinol Metab 1992; 74: 1352-1354.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1352-1354
    • Kawamura, N.1    Kawamura, N.2    Ookawara, T.3
  • 63
    • 0037099548 scopus 로고    scopus 로고
    • Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products
    • DOI 10.1016/S0003-9861(02)00222-9, PII S0003986102002229
    • Morgan PE, Morgan PE, Dean RT, et al,. Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products. Arch Biochem Biophys 2002; 403: 259-269. (Pubitemid 34800207)
    • (2002) Archives of Biochemistry and Biophysics , vol.403 , Issue.2 , pp. 259-269
    • Morgan, P.E.1    Dean, R.T.2    Davies, M.J.3
  • 64
    • 34249812373 scopus 로고    scopus 로고
    • Oxidative stress, antioxidant status and DNA damage in patients with impaired glucose regulation and newly diagnosed type 2 diabetes
    • DOI 10.1042/CS20060323
    • Song F, Jia W, Yao Y, et al,. Oxidative stress, antioxidant status and DNA damage in patients with impaired glucose regulation and newly diagnosed type 2 diabetes. Clin Sci 2007; 112: 599-606. (Pubitemid 46849550)
    • (2007) Clinical Science , vol.112 , Issue.11-12 , pp. 599-606
    • Song, F.1    Jia, W.2    Yao, Y.3    Hu, Y.4    Lei, L.5    Lin, J.6    Sun, X.7    Liu, L.8
  • 65
    • 0033009862 scopus 로고    scopus 로고
    • Free fatty acids, insulin resistance, and type 2 diabetes mellitus
    • DOI 10.1046/j.1525-1381.1999.99220.x
    • Boden G,. Free fatty acids, insulin resistance, and type 2 diabetes mellitus. Proc Assoc Am Physic 1999; 111: 241-248. (Pubitemid 29240904)
    • (1999) Proceedings of the Association of American Physicians , vol.111 , Issue.3 , pp. 241-248
    • Boden, G.1
  • 66
    • 0033765672 scopus 로고    scopus 로고
    • High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
    • Inoguchi T, Li P, Umeda F, et al,. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 2000; 49: 1939-1945.
    • (2000) Diabetes , vol.49 , pp. 1939-1945
    • Inoguchi, T.1    Li, P.2    Umeda, F.3
  • 67
  • 68
    • 84861583091 scopus 로고    scopus 로고
    • Oxidative stress in obese children and its relation with insulin resistance
    • Ozgen IT, Tascilar ME, Bilir P, et al,. Oxidative stress in obese children and its relation with insulin resistance. J Pediatr Endocrinol Metab 2012; 25: 261-266.
    • (2012) J Pediatr Endocrinol Metab , vol.25 , pp. 261-266
    • Ozgen, I.T.1    Tascilar, M.E.2    Bilir, P.3
  • 69
    • 63649106676 scopus 로고    scopus 로고
    • Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart
    • Boudina S, Bugger H, Sena S, et al,. Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. Circulation 2009; 119: 1272-1283.
    • (2009) Circulation , vol.119 , pp. 1272-1283
    • Boudina, S.1    Bugger, H.2    Sena, S.3
  • 70
    • 12744268367 scopus 로고    scopus 로고
    • Rosiglitazone treatment in Zucker diabetic fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion- induced myocardial injury
    • Yue T-L, Bao W, Gu J-L, et al,. Rosiglitazone treatment in Zucker diabetic fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion-induced myocardial injury. Diabetes 2005; 54: 554-562.
    • (2005) Diabetes , vol.54 , pp. 554-562
    • Yue, T.1    Bao, W.2    Gu, J.3
  • 71
    • 34548008730 scopus 로고    scopus 로고
    • Reperfusion injury salvage kinase signalling: Taking a RISK for cardioprotection
    • DOI 10.1007/s10741-007-9026-1, Special Issue on Cardioprotection; Guest Editors: Dennis V. Cokkinos and Gerd Heusch
    • Hausenloy DJ, Yellon DM,. Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection. Heart Fail Rev 2007; 12: 217-234. (Pubitemid 350176695)
    • (2007) Heart Failure Reviews , vol.12 , Issue.3-4 , pp. 217-234
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 73
    • 77955157002 scopus 로고    scopus 로고
    • Preconditioning the diabetic human myocardium
    • Sivaraman V, Hausenloy DJ, Wynne AM, et al,. Preconditioning the diabetic human myocardium. J Cell Mol Med 2010; 14: 1740-1746.
    • (2010) J Cell Mol Med , vol.14 , pp. 1740-1746
    • Sivaraman, V.1    Hausenloy, D.J.2    Wynne, A.M.3
  • 74
    • 23644447741 scopus 로고    scopus 로고
    • Preconditioning the diabetic heart: The importance of Akt phosphorylation
    • DOI 10.2337/diabetes.54.8.2360
    • Tsang A, Hausenloy DJ, Mocanu MM, et al,. Preconditioning the diabetic heart: the importance of Akt phosphorylation. Diabetes 2005; 54: 2360-2364. (Pubitemid 41134263)
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2360-2364
    • Tsang, A.1    Hausenloy, D.J.2    Mocanu, M.M.3    Carr, R.D.4    Yellon, D.M.5
  • 76
    • 65549150446 scopus 로고    scopus 로고
    • The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration
    • Kang KH, Lemke G, Kim JW,. The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. Trends Mol Med 2009; 15: 191-198.
    • (2009) Trends Mol Med , vol.15 , pp. 191-198
    • Kang, K.H.1    Lemke, G.2    Kim, J.W.3
  • 77
    • 33750692330 scopus 로고    scopus 로고
    • A potential role for PTEN in the diabetic heart
    • DOI 10.1007/s10557-006-8876-4
    • Mocanu MM, Field DC, Yellon DM,. A potential role for PTEN in the diabetic heart. Cardiovasc Drugs Ther 2006; 20: 319-321. (Pubitemid 44701164)
    • (2006) Cardiovascular Drugs and Therapy , vol.20 , Issue.4 , pp. 319-321
    • Mocanu, M.M.1    Field, D.C.2    Yellon, D.M.3
  • 78
    • 58149280238 scopus 로고    scopus 로고
    • Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury
    • Ruan H, Li J, Ren S, et al,. Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury. J Mol Cell Cardiol 2009; 46: 193-200.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 193-200
    • Ruan, H.1    Li, J.2    Ren, S.3
  • 79
    • 11144279346 scopus 로고    scopus 로고
    • The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is Phosphatase and Tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway
    • DOI 10.1091/mbc.E04-05-0369
    • Seo JH, Ahn Y, Lee S-R, et al,. The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway. Mol Biol Cell 2005; 16: 348-357. (Pubitemid 40024316)
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.1 , pp. 348-357
    • Seo, J.H.1    Ahn, Y.2    Lee, S.-R.3    Yeo, C.Y.4    Hur, K.C.5
  • 80
    • 34848892187 scopus 로고    scopus 로고
    • Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner
    • DOI 10.1161/CIRCULATIONAHA.107.716498
    • Song P, Wu Y, Xu J, et al,. Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner. Circulation 2007; 116: 1585-1595. (Pubitemid 47511422)
    • (2007) Circulation , vol.116 , Issue.14 , pp. 1585-1595
    • Song, P.1    Wu, Y.2    Xu, J.3    Xie, Z.4    Dong, Y.5    Zhang, M.6    Zou, M.-H.7
  • 81
    • 33749329784 scopus 로고    scopus 로고
    • Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase
    • DOI 10.2337/db05-1574
    • Wang XL, Wang XL, Zhang L, et al,. Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase. Diabetes 2006; 55: 2301-2310. (Pubitemid 44743628)
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2301-2310
    • Xing, L.W.1    Zhang, L.2    Youker, K.3    Zhang, M.-X.4    Wang, J.5    LeMaire, S.A.6    Coselli, J.S.7    Shen, Y.H.8
  • 82
    • 33645509709 scopus 로고    scopus 로고
    • Edelstein D, et al. Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
    • Xueliang, Xueliang
    • Xueliang, Xueliang, Edelstein D, et al. Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation. J Clin Invest 2006; 116: 1071-1080.
    • (2006) J Clin Invest , vol.116 , pp. 1071-1080
  • 83
    • 63349089932 scopus 로고    scopus 로고
    • Multiple protective pathways against reperfusion injury: A SAFE path without Aktion?
    • Lecour S,. Multiple protective pathways against reperfusion injury: a SAFE path without Aktion? J Mol Cell Cardiol 2009; 46: 607-609.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 607-609
    • Lecour, S.1
  • 84
    • 73349102809 scopus 로고    scopus 로고
    • STAT3 revs up the powerhouse
    • pe61
    • Reich NC,. STAT3 revs up the powerhouse. Sci Signal 2009; 2: pe61.
    • (2009) Sci Signal , vol.2
    • Reich, N.C.1
  • 85
    • 53749100817 scopus 로고    scopus 로고
    • The myocardial JAK/STAT pathway: From protection to failure
    • Boengler K, Hilfiker-Kleiner D, Drexler H, et al,. The myocardial JAK/STAT pathway: from protection to failure. Pharmacol Ther 2008; 120: 172-185.
    • (2008) Pharmacol Ther , vol.120 , pp. 172-185
    • Boengler, K.1    Hilfiker-Kleiner, D.2    Drexler, H.3
  • 86
    • 67349229765 scopus 로고    scopus 로고
    • Activation of the protective survivor activating factor enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?
    • Lecour S,. Activation of the protective survivor activating factor enhancement (SAFE) pathway against reperfusion injury: does it go beyond the RISK pathway? J Mol Cell Cardiol 2009; 47: 32-40.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 32-40
    • Lecour, S.1
  • 88
    • 59849101586 scopus 로고    scopus 로고
    • Function of mitochondrial Stat3 in cellular respiration
    • Wegrzyn J, Potla R, Chwae Y-J, et al,. Function of mitochondrial Stat3 in cellular respiration. Science 2009; 323: 793-797.
    • (2009) Science , vol.323 , pp. 793-797
    • Wegrzyn, J.1    Potla, R.2    Chwae, Y.3
  • 89
    • 78649324875 scopus 로고    scopus 로고
    • Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
    • Boengler K, Hilfiker-Kleiner D, Heusch G, et al,. Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion. Basic Res Cardiol 2010; 105: 771-785.
    • (2010) Basic Res Cardiol , vol.105 , pp. 771-785
    • Boengler, K.1    Hilfiker-Kleiner, D.2    Heusch, G.3
  • 90
    • 77958027773 scopus 로고    scopus 로고
    • Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore
    • Smith CCT, Dixon RA, Wynne AM, et al,. Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore. Am J Physiol Heart Circ Physiol 2010; 299: H1265-1270.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Smith, C.C.T.1    Dixon, R.A.2    Wynne, A.M.3
  • 91
    • 37849023059 scopus 로고    scopus 로고
    • Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice
    • Boengler K, Buechert A, Heinen Y, et al,. Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice. Circ Res 2008; 102: 131-135.
    • (2008) Circ Res , vol.102 , pp. 131-135
    • Boengler, K.1    Buechert, A.2    Heinen, Y.3
  • 92
    • 71549129836 scopus 로고    scopus 로고
    • Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway
    • Lacerda L, Somers S, Opie L, et al,. Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway. Cardiovasc Res 2009; 84: 201-208.
    • (2009) Cardiovasc Res , vol.84 , pp. 201-208
    • Lacerda, L.1    Somers, S.2    Opie, L.3
  • 95
    • 79958108043 scopus 로고    scopus 로고
    • Diabetes blockade of sevoflurane postconditioning is not restored by insulin in the rat heart: Phosphorylated signal transducer and activator of transcription 3- and phosphatidylinositol 3-kinase-mediated inhibition
    • Drenger B, Ostrovsky IA, Barak M, et al,. Diabetes blockade of sevoflurane postconditioning is not restored by insulin in the rat heart: phosphorylated signal transducer and activator of transcription 3- and phosphatidylinositol 3-kinase-mediated inhibition. Anesthesiology 2011; 114: 1364-1372.
    • (2011) Anesthesiology , vol.114 , pp. 1364-1372
    • Drenger, B.1    Ostrovsky, I.A.2    Barak, M.3
  • 96
    • 44449147923 scopus 로고    scopus 로고
    • Cardiac ischemia and reperfusion in spontaneously diabetic rats with and without application of EGb 761: I. cardiomyocytes
    • Schneider R, Welt K, Aust W, et al,. Cardiac ischemia and reperfusion in spontaneously diabetic rats with and without application of EGb 761: I. cardiomyocytes. Histol Histopathol 2008; 23: 807-817.
    • (2008) Histol Histopathol , vol.23 , pp. 807-817
    • Schneider, R.1    Welt, K.2    Aust, W.3
  • 97
    • 61949182565 scopus 로고    scopus 로고
    • Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore
    • Ananthakrishnan R, Ananthakrishnan R, Kaneko M, et al,. Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore. Am J Physiol Heart Circ Physiol 2009; 296: H333-341.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Ananthakrishnan, R.1    Ananthakrishnan, R.2    Kaneko, M.3
  • 98
    • 77953476519 scopus 로고    scopus 로고
    • Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins
    • Tang WH, Tang WH, Kravtsov GM, et al,. Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins. J Mol Cell Cardiol 2010; 49: 58-69.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 58-69
    • Tang, W.H.1    Tang, W.H.2    Kravtsov, G.M.3
  • 99
    • 48449094505 scopus 로고    scopus 로고
    • Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart
    • Tang WH, Tang WH, Wu S, et al,. Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. Free Rad Biol Med 2008; 45: 602-610.
    • (2008) Free Rad Biol Med , vol.45 , pp. 602-610
    • Tang, W.H.1    Tang, W.H.2    Wu, S.3
  • 100
    • 0035180299 scopus 로고    scopus 로고
    • Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
    • DOI 10.1172/JCI200111235
    • Du XL, Edelstein D, Dimmeler S, et al,. Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 2001; 108: 1341-1348. (Pubitemid 33107762)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.9 , pp. 1341-1348
    • Du, X.L.1    Edelstein, D.2    Dimmeler, S.3    Ju, Q.4    Sui, C.5    Brownlee, M.6
  • 101
    • 0037162342 scopus 로고    scopus 로고
    • Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells
    • DOI 10.1161/01.CIR.0000023043.02648.51
    • Federici M, Menghini R, Mauriello A, et al,. Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells. Circulation 2002; 106: 466-472. (Pubitemid 34803692)
    • (2002) Circulation , vol.106 , Issue.4 , pp. 466-472
    • Federici, M.1    Menghini, R.2    Mauriello, A.3    Hribal, M.L.4    Ferrelli, F.5    Lauro, D.6    Sbraccia, P.7    Spagnoli, L.G.8    Sesti, G.9    Lauro, R.10
  • 102
    • 79954433818 scopus 로고    scopus 로고
    • Dell'Italia LJ, Chatham JC. Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice
    • Marsh SA, Dell'Italia LJ, Chatham JC. Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice. Amino Acids 2011; 40: 819-828.
    • (2011) Amino Acids , vol.40 , pp. 819-828
    • Marsh, S.A.1
  • 103
    • 79955649810 scopus 로고    scopus 로고
    • The hexosamine biosynthetic pathway can mediate myocardial apoptosis in a rat model of diet-induced insulin resistance
    • Rajamani U, Joseph D, Roux S, et al,. The hexosamine biosynthetic pathway can mediate myocardial apoptosis in a rat model of diet-induced insulin resistance. Acta Physiol (Oxf) 2011; 202: 151-157.
    • (2011) Acta Physiol (Oxf) , vol.202 , pp. 151-157
    • Rajamani, U.1    Joseph, D.2    Roux, S.3
  • 104
    • 77950402132 scopus 로고    scopus 로고
    • Relationship between apoptotic markers (Bax and Bcl-2) and biochemical markers in type 2 diabetes mellitus
    • Hasnan J, Yusof MI, Damitri TD, et al,. Relationship between apoptotic markers (Bax and Bcl-2) and biochemical markers in type 2 diabetes mellitus. Singapore Med J 2010; 51: 50-55.
    • (2010) Singapore Med J , vol.51 , pp. 50-55
    • Hasnan, J.1    Yusof, M.I.2    Damitri, T.D.3
  • 105
    • 21244502594 scopus 로고    scopus 로고
    • Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury
    • Song Y, Wang J, Li Y, et al,. Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury. Am J Pathol 2005; 167: 17-26. (Pubitemid 40884766)
    • (2005) American Journal of Pathology , vol.167 , Issue.1 , pp. 17-26
    • Song, Y.1    Wang, J.2    Li, V.3    Du, Y.4    Arteel, G.E.5    Saari, J.T.6    Kang, Y.J.7    Cai, L.8
  • 107
    • 78649519676 scopus 로고    scopus 로고
    • STAT3 modulates the DNA damage response pathway
    • Barry SP, Townsend PA, Knight RA, et al,. STAT3 modulates the DNA damage response pathway. Int J Exp Pathol 2010; 91: 506-514.
    • (2010) Int J Exp Pathol , vol.91 , pp. 506-514
    • Barry, S.P.1    Townsend, P.A.2    Knight, R.A.3
  • 109
    • 14644400430 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates myocardial ischemia/reperfusion injury in diabetic mice
    • DOI 10.2337/diabetes.54.3.778
    • Liu X, Wei J, Peng DH, et al,. Absence of heme oxygenase-1 exacerbates myocardial ischemia/reperfusion injury in diabetic mice. Diabetes 2005; 54: 778-784. (Pubitemid 40322082)
    • (2005) Diabetes , vol.54 , Issue.3 , pp. 778-784
    • Liu, X.1    Wei, J.2    Peng, D.H.3    Layne, M.D.4    Yet, S.-F.5
  • 110
    • 67650257495 scopus 로고    scopus 로고
    • High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation
    • Luan R, Liu S, Yin T, et al,. High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation. Cardiovasc Res 2009; 83: 294-302.
    • (2009) Cardiovasc Res , vol.83 , pp. 294-302
    • Luan, R.1    Liu, S.2    Yin, T.3
  • 111
    • 77955270298 scopus 로고    scopus 로고
    • Nitrative inactivation of thioredoxin-1 increases vulnerability of diabetic hearts to ischemia/reperfusion injury
    • Yin T, Hou R, Liu S, et al,. Nitrative inactivation of thioredoxin-1 increases vulnerability of diabetic hearts to ischemia/reperfusion injury. J Mol Cell Cardiol 2010; 49: 354-361.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 354-361
    • Yin, T.1    Hou, R.2    Liu, S.3
  • 112
    • 77954911547 scopus 로고    scopus 로고
    • Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity
    • Wang XL, Lau WB, Yuan YX, et al,. Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity. Am J Physiol Endocrinol Metab 2010; 299: E207-214.
    • (2010) Am J Physiol Endocrinol Metab , vol.299
    • Wang, X.L.1    Lau, W.B.2    Yuan, Y.X.3
  • 113
    • 34548766577 scopus 로고    scopus 로고
    • Oxidative stress and cardiac repair/remodeling following infarction
    • DOI 10.1097/MAJ.0b013e318157388f, PII 0000044120070900000011
    • Sun Y,. Oxidative stress and cardiac repair/remodeling following infarction. Am J Med Sci 2007; 334: 197-205. (Pubitemid 47430570)
    • (2007) American Journal of the Medical Sciences , vol.334 , Issue.3 , pp. 197-205
    • Sun, Y.1
  • 114
    • 59449107442 scopus 로고    scopus 로고
    • Myocardial repair/remodelling following infarction: Roles of local factors
    • Sun Y,. Myocardial repair/remodelling following infarction: roles of local factors. Cardiovasc Res 2009; 81: 482-490.
    • (2009) Cardiovasc Res , vol.81 , pp. 482-490
    • Sun, Y.1
  • 115
    • 84871091393 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice
    • Eguchi M, Eguchi M, Kim YH, et al,. Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice. PloS One 2012; 7: 1-10.
    • (2012) PloS One , vol.7 , pp. 1-10
    • Eguchi, M.1    Eguchi, M.2    Kim, Y.H.3
  • 116
    • 24944490072 scopus 로고    scopus 로고
    • Greater propensity of diabetic myocardium for oxidative stress after myocardial infarction is associated with the development of heart failure
    • DOI 10.1016/j.yjmcc.2005.07.004, PII S0022282805002233
    • Smith HM, Smith HM, Hamblin M, et al,. Greater propensity of diabetic myocardium for oxidative stress after myocardial infarction is associated with the development of heart failure. J Mol Cell Cardiol 2005; 39: 657-665. (Pubitemid 41331054)
    • (2005) Journal of Molecular and Cellular Cardiology , vol.39 , Issue.4 , pp. 657-665
    • Smith, H.M.1    Hamblin, M.2    Hill, M.F.3
  • 117
    • 37549058838 scopus 로고    scopus 로고
    • Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats
    • Aragno M, Mastrocola R, Alloatti G, et al,. Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats. Endocrinology 2008; 149: 380-388.
    • (2008) Endocrinology , vol.149 , pp. 380-388
    • Aragno, M.1    Mastrocola, R.2    Alloatti, G.3
  • 118
    • 67650221201 scopus 로고    scopus 로고
    • Autophagy, redox signaling, and ventricular remodeling
    • Gurusamy N, Das DK,. Autophagy, redox signaling, and ventricular remodeling. Antioxid Redox Signal 2009; 11: 1975-1988.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1975-1988
    • Gurusamy, N.1    Das, D.K.2
  • 119
    • 67349258584 scopus 로고    scopus 로고
    • Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction
    • Sena S, Sena S, Hu P, et al,. Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction. J Mol Cell Cardiol 2009; 46: 910-918.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 910-918
    • Sena, S.1    Sena, S.2    Hu, P.3
  • 120
    • 78651326461 scopus 로고    scopus 로고
    • Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways
    • Anderson EJ, Anderson EJ, Rodriguez E, et al,. Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. AmJ Physiol Heart Circ Physiol 2011; 300: H118-124.
    • (2011) AmJ Physiol Heart Circ Physiol , vol.300
    • Anderson, E.J.1    Anderson, E.J.2    Rodriguez, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.