Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 299, Issue 4, 2010, Pages

  Smith, Christopher C T ^a   Dixon, Richard A ^a   Wynne, Abigail M ^a   Theodorou, Louise ^a   Ong, Sang Ging ^a   Subrayan, Sapna ^a   Davidson, Sean M ^a   Hausenloy, Derek J ^a   Yellon, Derek M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Ischemia reperfusion injury; Janus activated kinase signal transducer and activator of transcription signaling; Myocardium

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; JANUS KINASE; LEPTIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT PROTEIN; STAT3 PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; RESPIRATORY CHAIN; WESTERN BLOTTING;

ANIMALS; ENZYME INHIBITORS; JANUS KINASE 2; JANUS KINASES; LEPTIN; MALE; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MODELS, ANIMAL; MYOCARDIAL REPERFUSION INJURY; PHOSPHORYLATION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; STAT3 TRANSCRIPTION FACTOR; TYRPHOSTINS;

EID: 77958027773     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00092.2010     Document Type: Article

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