Protein profiling of active cysteine cathepsins in living cells using an activity-based probe containing a cell-penetrating peptide

Journal of Proteome Research

Volumn 11, Issue 12, 2012, Pages 5763-5772

  Fan, Fengkai ^a,b   Nie, Si ^a,b   Dammer, Eric B ^d   Duong, Duc M ^d   Pan, Deng ^a,b   Ping, Lingyan ^c,e   Zhai, Linhui ^c,f   Wu, Junzhu ^e   Hong, Xuechuan ^f   Qin, Lingsong ^a,b   Xu, Ping ^c,f   Zhang, Yu Hui ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WUHAN UNIVERSITY   (China)

^f WUHAN UNIVERSITY   (China)

Author keywords

activity based probe; cathepsin; cell penetrating peptide; living cell; proteomics

Indexed keywords

BIOTIN; CATHEPSIN; CATHEPSIN B; CATHEPSIN F; CATHEPSIN H; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; CATHEPSIN X; CELL PENETRATING PEPTIDE; CELL PERMEABLE ACTIVITY BASED PROBE; CYSTEINE; DIPEPTIDYL PEPTIDASE I; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN SYNTHESIS; PROTEOMICS; PURIFICATION;

AFFINITY LABELS; ANIMALS; CATHEPSINS; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CELL-PENETRATING PEPTIDES; CYSTEINE; ENZYME ACTIVATION; FLUORESCENT DYES; HUMANS; MACROPHAGES; MICE; MICROSCOPY, CONFOCAL; MOLECULAR PROBES; PROTEIN ARRAY ANALYSIS; PROTEIN TRANSPORT; PROTEOMICS; RNA, MESSENGER; SOLID-PHASE SYNTHESIS TECHNIQUES; SUBSTRATE SPECIFICITY;

EID: 84870923936     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300575u     Document Type: Article

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