-
1
-
-
28944446580
-
The role of His-18 in amyloid formation by human islet amyloid polypeptide
-
Abedini A., Raleigh D.P. The role of His-18 in amyloid formation by human islet amyloid polypeptide. Biochemistry 2005, 44:16284-16291.
-
(2005)
Biochemistry
, vol.44
, pp. 16284-16291
-
-
Abedini, A.1
Raleigh, D.P.2
-
2
-
-
28944455381
-
Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP
-
Abedini A., Raleigh D.P. Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP. Journal of Molecular Biology 2006, 355:274-281.
-
(2006)
Journal of Molecular Biology
, vol.355
, pp. 274-281
-
-
Abedini, A.1
Raleigh, D.P.2
-
3
-
-
83055192097
-
Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone
-
Andreasen M., Nielsen S.B., Mittag T., Bjerring M., Nielsen J.T., Zhang S., Nielsen E.H., Jeppesen M., Christiansen G., Besenbacher F., Dong M., Nielsen N.C., Skrydstrup T., Otzen D.E. Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone. Biochimica et Biophysica Acta 2012, 1824:274-285.
-
(2012)
Biochimica et Biophysica Acta
, vol.1824
, pp. 274-285
-
-
Andreasen, M.1
Nielsen, S.B.2
Mittag, T.3
Bjerring, M.4
Nielsen, J.T.5
Zhang, S.6
Nielsen, E.H.7
Jeppesen, M.8
Christiansen, G.9
Besenbacher, F.10
Dong, M.11
Nielsen, N.C.12
Skrydstrup, T.13
Otzen, D.E.14
-
4
-
-
39049110070
-
Apolipoprotein C-II amyloid fibrils assemble via a reversible pathway that includes fibril breaking and rejoining
-
Binger K.J., Pham C.L.L., Wilson L.M., Bailey M.F., Lawrence L.J., Schuck P., Howlett G.J. Apolipoprotein C-II amyloid fibrils assemble via a reversible pathway that includes fibril breaking and rejoining. Journal of Molecular Biology 2008, 376:1116-1129.
-
(2008)
Journal of Molecular Biology
, vol.376
, pp. 1116-1129
-
-
Binger, K.J.1
Pham, C.L.L.2
Wilson, L.M.3
Bailey, M.F.4
Lawrence, L.J.5
Schuck, P.6
Howlett, G.J.7
-
5
-
-
0016717899
-
An essential arginyl residue at the nucleotide binding site of creatine kinase
-
Borders C.L., Riordan J.F. An essential arginyl residue at the nucleotide binding site of creatine kinase. Biochemistry 1975, 14:4699-4704.
-
(1975)
Biochemistry
, vol.14
, pp. 4699-4704
-
-
Borders, C.L.1
Riordan, J.F.2
-
6
-
-
34548494605
-
Membrane fragmentation by an amyloidogenic fragment of human islet amyloid polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes
-
Brender J.R., Dürr U.H.N., Heyl D., Budarapu M.B., Ramamoorthy A. Membrane fragmentation by an amyloidogenic fragment of human islet amyloid polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes. Biochimica et Biophysica Acta 2007, 1768:2026-2029.
-
(2007)
Biochimica et Biophysica Acta
, vol.1768
, pp. 2026-2029
-
-
Brender, J.R.1
Dürr, U.H.N.2
Heyl, D.3
Budarapu, M.B.4
Ramamoorthy, A.5
-
7
-
-
77954269081
-
Role of zinc in human islet amyloid polypeptide aggregation
-
Brender J.R., Hartman K., Nanga R.P.R., Popovych N., de La Salud Bea R., Vivekanandan S., Marsh E.N.G., Ramamoorthy A. Role of zinc in human islet amyloid polypeptide aggregation. Journal of the American Chemical Society 2010, 132:8973-8983.
-
(2010)
Journal of the American Chemical Society
, vol.132
, pp. 8973-8983
-
-
Brender, J.R.1
Hartman, K.2
Nanga, R.P.R.3
Popovych, N.4
de La Salud Bea, R.5
Vivekanandan, S.6
Marsh, E.N.G.7
Ramamoorthy, A.8
-
8
-
-
57049086457
-
A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity
-
Brender J.R., Hartman K., Reid K.R., Kennedy R.T., Ramamoorthy A. A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity. Biochemistry 2008, 47:12680-12688.
-
(2008)
Biochemistry
, vol.47
, pp. 12680-12688
-
-
Brender, J.R.1
Hartman, K.2
Reid, K.R.3
Kennedy, R.T.4
Ramamoorthy, A.5
-
9
-
-
43949107500
-
Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide
-
Brender J.R., Lee E.L., Cavitt M.A., Gafni A., Steel D.G., Ramamoorthy A. Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide. Journal of the American Chemical Society 2008, 130:6424-6429.
-
(2008)
Journal of the American Chemical Society
, vol.130
, pp. 6424-6429
-
-
Brender, J.R.1
Lee, E.L.2
Cavitt, M.A.3
Gafni, A.4
Steel, D.G.5
Ramamoorthy, A.6
-
10
-
-
84858632761
-
Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective
-
Brender J.R., Salamekh S., Ramamoorthy A. Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective. Accounts of Chemical Research 2012, 45:454-462.
-
(2012)
Accounts of Chemical Research
, vol.45
, pp. 454-462
-
-
Brender, J.R.1
Salamekh, S.2
Ramamoorthy, A.3
-
11
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler A.E., Janson J., Bonner-Weir S., Ritzel R., Rizza R.A., Butler P.C. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003, 52:102-110.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
13
-
-
4644308854
-
Chemical modification of arginine residues of Notechis scutatus scutatus notexin
-
Chang L.-S., Wu P.-F., Liou J.-C., Chiang-Lin W.-H., Yang C.-C. Chemical modification of arginine residues of Notechis scutatus scutatus notexin. Toxicon 2004, 44:491-497.
-
(2004)
Toxicon
, vol.44
, pp. 491-497
-
-
Chang, L.-S.1
Wu, P.-F.2
Liou, J.-C.3
Chiang-Lin, W.-H.4
Yang, C.-C.5
-
14
-
-
0028886748
-
Effect of pH and insulin on fibrillogenesis of islet amyloid polypeptide in vitro
-
Chargé S.B., de Koning E.J., Clark A. Effect of pH and insulin on fibrillogenesis of islet amyloid polypeptide in vitro. Biochemistry 1995, 34:14588-14593.
-
(1995)
Biochemistry
, vol.34
, pp. 14588-14593
-
-
Chargé, S.B.1
de Koning, E.J.2
Clark, A.3
-
15
-
-
84862817939
-
Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide
-
Cheng B., Gong H., Li X., Sun Y., Zhang X., Chen H., Liu X., Zheng L., Huang K. Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide. Biochemical and Biophysical Research Communications 2012, 419:495-499.
-
(2012)
Biochemical and Biophysical Research Communications
, vol.419
, pp. 495-499
-
-
Cheng, B.1
Gong, H.2
Li, X.3
Sun, Y.4
Zhang, X.5
Chen, H.6
Liu, X.7
Zheng, L.8
Huang, K.9
-
16
-
-
1542375103
-
Islet amyloid: a complication of islet dysfunction or an aetiological factor in type 2 diabetes?
-
Clark A., Nilsson M.R. Islet amyloid: a complication of islet dysfunction or an aetiological factor in type 2 diabetes?. Diabetologia 2004, 47:157-169.
-
(2004)
Diabetologia
, vol.47
, pp. 157-169
-
-
Clark, A.1
Nilsson, M.R.2
-
17
-
-
84858374665
-
The amyloid state of proteins in human diseases
-
Eisenberg D., Jucker M. The amyloid state of proteins in human diseases. Cell 2012, 148:1188-1203.
-
(2012)
Cell
, vol.148
, pp. 1188-1203
-
-
Eisenberg, D.1
Jucker, M.2
-
18
-
-
33846023647
-
Lysozyme amyloid oligomers and fibrils induce cellular death via different apoptotic/necrotic pathways
-
Gharibyan A.L., Zamotin V., Yanamandra K., Moskaleva O.S., Margulis B.A., Kostanyan I.A., Morozova-Roche L.A. Lysozyme amyloid oligomers and fibrils induce cellular death via different apoptotic/necrotic pathways. Journal of Molecular Biology 2007, 365:1337-1349.
-
(2007)
Journal of Molecular Biology
, vol.365
, pp. 1337-1349
-
-
Gharibyan, A.L.1
Zamotin, V.2
Yanamandra, K.3
Moskaleva, O.S.4
Margulis, B.A.5
Kostanyan, I.A.6
Morozova-Roche, L.A.7
-
19
-
-
0033534397
-
Watching amyloid fibrils grow by time-lapse atomic force microscopy
-
Goldsbury C., Kistler J., Aebi U., Arvinte T., Cooper G.J. Watching amyloid fibrils grow by time-lapse atomic force microscopy. Journal of Molecular Biology 1999, 285:33-39.
-
(1999)
Journal of Molecular Biology
, vol.285
, pp. 33-39
-
-
Goldsbury, C.1
Kistler, J.2
Aebi, U.3
Arvinte, T.4
Cooper, G.J.5
-
21
-
-
0037470589
-
Full-length rat amylin forms fibrils following substitution of single residues from human amylin
-
Green J., Goldsbury C., Mini T., Sunderji S., Frey P., Kistler J., Cooper G., Aebi U. Full-length rat amylin forms fibrils following substitution of single residues from human amylin. Journal of Molecular Biology 2003, 326:1147-1156.
-
(2003)
Journal of Molecular Biology
, vol.326
, pp. 1147-1156
-
-
Green, J.1
Goldsbury, C.2
Mini, T.3
Sunderji, S.4
Frey, P.5
Kistler, J.6
Cooper, G.7
Aebi, U.8
-
22
-
-
55549093782
-
Fragmentation of fiberlike structures: sonication studies of cylindrical block copolymer micelles and behavioral comparisons to biological fibrils
-
Guérin G., Wang H., Manners I., Winnik M.A. Fragmentation of fiberlike structures: sonication studies of cylindrical block copolymer micelles and behavioral comparisons to biological fibrils. Journal of the American Chemical Society 2008, 130:14763-14771.
-
(2008)
Journal of the American Chemical Society
, vol.130
, pp. 14763-14771
-
-
Guérin, G.1
Wang, H.2
Manners, I.3
Winnik, M.A.4
-
23
-
-
78649820608
-
Inhibitors of catalase-amyloid interactions protect cells from beta-amyloid-induced oxidative stress and toxicity
-
Habib L.K., Lee M.T.C., Yang J. Inhibitors of catalase-amyloid interactions protect cells from beta-amyloid-induced oxidative stress and toxicity. Journal of Biological Chemistry 2010, 285:38933-38943.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 38933-38943
-
-
Habib, L.K.1
Lee, M.T.C.2
Yang, J.3
-
24
-
-
0030686409
-
Rat amylin-(8-37) enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats
-
Hettiarachchi M., Chalkley S., Furler S.M., Choong Y.S., Heller M., Cooper G.J., Kraegen E.W. Rat amylin-(8-37) enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats. American Journal of Physiology 1997, 273:E859-E867.
-
(1997)
American Journal of Physiology
, vol.273
-
-
Hettiarachchi, M.1
Chalkley, S.2
Furler, S.M.3
Choong, Y.S.4
Heller, M.5
Cooper, G.J.6
Kraegen, E.W.7
-
25
-
-
0035804936
-
Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis
-
Jaikaran E.T., Higham C.E., Serpell L.C., Zurdo J., Gross M., Clark A., Fraser P.E. Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis. Journal of Molecular Biology 2001, 308:515-525.
-
(2001)
Journal of Molecular Biology
, vol.308
, pp. 515-525
-
-
Jaikaran, E.T.1
Higham, C.E.2
Serpell, L.C.3
Zurdo, J.4
Gross, M.5
Clark, A.6
Fraser, P.E.7
-
26
-
-
79251473696
-
Actions of β-amyloid protein on human neurons are expressed through the amylin receptor
-
Jhamandas J.H., Li Z., Westaway D., Yang J., Jassar S., MacTavish D. Actions of β-amyloid protein on human neurons are expressed through the amylin receptor. American Journal of Pathology 2011, 178:140-149.
-
(2011)
American Journal of Pathology
, vol.178
, pp. 140-149
-
-
Jhamandas, J.H.1
Li, Z.2
Westaway, D.3
Yang, J.4
Jassar, S.5
MacTavish, D.6
-
27
-
-
84856718443
-
β-Amyloid protein (Aβ) and human amylin regulation of apoptotic genes occurs through the amylin receptor
-
Jhamandas J.H., MacTavish D. β-Amyloid protein (Aβ) and human amylin regulation of apoptotic genes occurs through the amylin receptor. Apoptosis 2012, 17:37-47.
-
(2012)
Apoptosis
, vol.17
, pp. 37-47
-
-
Jhamandas, J.H.1
MacTavish, D.2
-
28
-
-
80052266213
-
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
-
Karran E., Mercken M., Strooper B.D. The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics. Nature Reviews: Drug Discovery 2011, 10:698-712.
-
(2011)
Nature Reviews: Drug Discovery
, vol.10
, pp. 698-712
-
-
Karran, E.1
Mercken, M.2
Strooper, B.D.3
-
29
-
-
0034640372
-
Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line
-
Kawahara M., Kuroda Y., Arispe N., Rojas E. Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. Journal of Biological Chemistry 2000, 275:14077-14083.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 14077-14083
-
-
Kawahara, M.1
Kuroda, Y.2
Arispe, N.3
Rojas, E.4
-
30
-
-
0032899322
-
Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay
-
Klunk W.E., Jacob R.F., Mason R.P. Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay. Analytical Biochemistry 1999, 266:66-76.
-
(1999)
Analytical Biochemistry
, vol.266
, pp. 66-76
-
-
Klunk, W.E.1
Jacob, R.F.2
Mason, R.P.3
-
31
-
-
77955658749
-
Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3
-
Law E., Lu S., Kieffer T.J., Warnock G.L., Ao Z., Woo M., Marzban L. Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3. Diabetologia 2010, 53:1415-1427.
-
(2010)
Diabetologia
, vol.53
, pp. 1415-1427
-
-
Law, E.1
Lu, S.2
Kieffer, T.J.3
Warnock, G.L.4
Ao, Z.5
Woo, M.6
Marzban, L.7
-
32
-
-
0003845791
-
Rat amylin: cloning and tissue-specific expression in pancreatic islets
-
Leffert J.D., Newgard C.B., Okamoto H., Milburn J.L., Luskey K.L. Rat amylin: cloning and tissue-specific expression in pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America 1989, 86:3127-3130.
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, pp. 3127-3130
-
-
Leffert, J.D.1
Newgard, C.B.2
Okamoto, H.3
Milburn, J.L.4
Luskey, K.L.5
-
33
-
-
72349097505
-
Abeta(31-35)-induced neuronal apoptosis is mediated by JNK-dependent extrinsic apoptosis pathway
-
Li L.-M., Liu Q.-H., Qiao J.-T., Zhang C. Abeta(31-35)-induced neuronal apoptosis is mediated by JNK-dependent extrinsic apoptosis pathway. Neuroscience Bulletin 2009, 25:361-366.
-
(2009)
Neuroscience Bulletin
, vol.25
, pp. 361-366
-
-
Li, L.-M.1
Liu, Q.-H.2
Qiao, J.-T.3
Zhang, C.4
-
34
-
-
79952101635
-
Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: an effect attenuated by phycocyanin
-
Li X.-L., Chen T., Wong Y.-S., Xu G., Fan R.-R., Zhao H.-L., Chan J.C.N. Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: an effect attenuated by phycocyanin. The International Journal of Biochemistry & Cell Biology 2011, 43:525-534.
-
(2011)
The International Journal of Biochemistry & Cell Biology
, vol.43
, pp. 525-534
-
-
Li, X.-L.1
Chen, T.2
Wong, Y.-S.3
Xu, G.4
Fan, R.-R.5
Zhao, H.-L.6
Chan, J.C.N.7
-
35
-
-
44749083630
-
Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures
-
Lim Y.-A., Ittner L.M., Lim Y.L., Götz J. Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures. FEBS Letters 2008, 582:2188-2194.
-
(2008)
FEBS Letters
, vol.582
, pp. 2188-2194
-
-
Lim, Y.-A.1
Ittner, L.M.2
Lim, Y.L.3
Götz, J.4
-
36
-
-
77951044468
-
Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction
-
Lim Y.-A., Rhein V., Baysang G., Meier F., Poljak A., Raftery M.J., Guilhaus M., Ittner L.M., Eckert A., Götz J. Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics 2010, 10:1621-1633.
-
(2010)
Proteomics
, vol.10
, pp. 1621-1633
-
-
Lim, Y.-A.1
Rhein, V.2
Baysang, G.3
Meier, F.4
Poljak, A.5
Raftery, M.J.6
Guilhaus, M.7
Ittner, L.M.8
Eckert, A.9
Götz, J.10
-
37
-
-
36749033116
-
Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR
-
Luca S., Yau W.-M., Leapman R., Tycko R. Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR. Biochemistry 2007, 46:13505-13522.
-
(2007)
Biochemistry
, vol.46
, pp. 13505-13522
-
-
Luca, S.1
Yau, W.-M.2
Leapman, R.3
Tycko, R.4
-
38
-
-
84862902637
-
Control of energy homeostasis by amylin
-
Lutz T.A. Control of energy homeostasis by amylin. Cellular and Molecular Life Sciences 2012, 69:1947-1965.
-
(2012)
Cellular and Molecular Life Sciences
, vol.69
, pp. 1947-1965
-
-
Lutz, T.A.1
-
39
-
-
57349120654
-
Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction
-
Madine J., Jack E., Stockley P.G., Radford S.E., Serpell L.C., Middleton D.A. Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction. Journal of the American Chemical Society 2008, 130:14990-15001.
-
(2008)
Journal of the American Chemical Society
, vol.130
, pp. 14990-15001
-
-
Madine, J.1
Jack, E.2
Stockley, P.G.3
Radford, S.E.4
Serpell, L.C.5
Middleton, D.A.6
-
40
-
-
83755178092
-
Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies
-
Mao X.-B., Wang C.-X., Wu X.-K., Ma X.-J., Liu L., Zhang L., Niu L., Guo Y.-Y., Li D.-H., Yang Y.-L., Wang C. Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:19605-19610.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 19605-19610
-
-
Mao, X.-B.1
Wang, C.-X.2
Wu, X.-K.3
Ma, X.-J.4
Liu, L.5
Zhang, L.6
Niu, L.7
Guo, Y.-Y.8
Li, D.-H.9
Yang, Y.-L.10
Wang, C.11
-
41
-
-
0028916920
-
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium
-
Mattson M.P., Goodman Y. Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium. Brain Research 1995, 676:219-224.
-
(1995)
Brain Research
, vol.676
, pp. 219-224
-
-
Mattson, M.P.1
Goodman, Y.2
-
42
-
-
79959331354
-
Development and functional characterization of insulin-releasing human pancreatic beta cell lines produced by electrofusion
-
McCluskey J.T., Hamid M., Guo-Parke H., McClenaghan N.H., Gomis R., Flatt P.R. Development and functional characterization of insulin-releasing human pancreatic beta cell lines produced by electrofusion. Journal of Biological Chemistry 2011, 286:21982-21992.
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 21982-21992
-
-
McCluskey, J.T.1
Hamid, M.2
Guo-Parke, H.3
McClenaghan, N.H.4
Gomis, R.5
Flatt, P.R.6
-
43
-
-
84860232628
-
Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor
-
Middleton C.T., Marek P., Cao P., Chiu C.-C., Singh S., Woys A.M., de Pablo J.J., Raleigh D.P., Zanni M.T. Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor. Nature Chemistry 2012, 4:355-360.
-
(2012)
Nature Chemistry
, vol.4
, pp. 355-360
-
-
Middleton, C.T.1
Marek, P.2
Cao, P.3
Chiu, C.-C.4
Singh, S.5
Woys, A.M.6
de Pablo, J.J.7
Raleigh, D.P.8
Zanni, M.T.9
-
44
-
-
79151479683
-
The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH
-
Milardi D., Sciacca M.F.M., Pappalardo M., Grasso D.M., La Rosa C. The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH. European Biophysics Journal 2011, 40:1-12.
-
(2011)
European Biophysics Journal
, vol.40
, pp. 1-12
-
-
Milardi, D.1
Sciacca, M.F.M.2
Pappalardo, M.3
Grasso, D.M.4
La Rosa, C.5
-
45
-
-
0033430085
-
Amyloid-beta binds catalase with high affinity and inhibits hydrogen peroxide breakdown
-
Milton N.G.N. Amyloid-beta binds catalase with high affinity and inhibits hydrogen peroxide breakdown. Biochemical Journal 1999, 344(Pt 2):293-296.
-
(1999)
Biochemical Journal
, vol.344
, Issue.PART 2
, pp. 293-296
-
-
Milton, N.G.N.1
-
46
-
-
0035696298
-
Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-beta peptide
-
Milton N.G.N. Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-beta peptide. Neurotoxicology 2001, 22:767-774.
-
(2001)
Neurotoxicology
, vol.22
, pp. 767-774
-
-
Milton, N.G.N.1
-
47
-
-
84866401574
-
Amyloid-β phosphorylation
-
John Wiley & Sons Ltd., Chichester, England, J.R. Harris, J.M. Graham, D. Rickwood (Eds.)
-
Milton N.G.N. Amyloid-β phosphorylation. Cell Biology Protocols 2006, 364-368. John Wiley & Sons Ltd., Chichester, England. J.R. Harris, J.M. Graham, D. Rickwood (Eds.).
-
(2006)
Cell Biology Protocols
, pp. 364-368
-
-
Milton, N.G.N.1
-
48
-
-
84858205680
-
Homocysteine inhibits hydrogen peroxide breakdown by catalase
-
Milton N.G.N. Homocysteine inhibits hydrogen peroxide breakdown by catalase. The Open Enzyme Inhibition Journal 2008, 1:34-41.
-
(2008)
The Open Enzyme Inhibition Journal
, vol.1
, pp. 34-41
-
-
Milton, N.G.N.1
-
49
-
-
84866371171
-
Kisspeptin prevention of amyloid-β peptide neurotoxicity in vitro
-
in press. doi:10.1021/cn300045d
-
Milton, N.G.N., Chilumuri, A., Rocha-Ferreira, E., Nercessian, A.N., Ashioti, M., 2012. Kisspeptin prevention of amyloid-β peptide neurotoxicity in vitro. ACS Chemical Neuroscience, in press. doi:10.1021/cn300045d.
-
(2012)
ACS Chemical Neuroscience
-
-
Milton, N.G.N.1
Chilumuri, A.2
Rocha-Ferreira, E.3
Nercessian, A.N.4
Ashioti, M.5
-
50
-
-
69249205408
-
Polymorphism of amyloid-beta fibrils and its effects on human erythrocyte catalase binding
-
Milton N.G.N., Harris J.R. Polymorphism of amyloid-beta fibrils and its effects on human erythrocyte catalase binding. Micron 2009, 40:800-810.
-
(2009)
Micron
, vol.40
, pp. 800-810
-
-
Milton, N.G.N.1
Harris, J.R.2
-
51
-
-
77953452374
-
Human islet amyloid polypeptide fibril binding to catalase: a transmission electron microscopy and microplate study
-
Milton N.G.N., Harris J.R. Human islet amyloid polypeptide fibril binding to catalase: a transmission electron microscopy and microplate study. TheScientificWorldJournal 2010, 10:879-893.
-
(2010)
TheScientificWorldJournal
, vol.10
, pp. 879-893
-
-
Milton, N.G.N.1
Harris, J.R.2
-
52
-
-
0035828169
-
Identification of amyloid-beta binding sites using an antisense peptide approach
-
Milton N.G.N., Mayor N.P., Rawlinson J. Identification of amyloid-beta binding sites using an antisense peptide approach. Neuroreport 2001, 12:2561-2566.
-
(2001)
Neuroreport
, vol.12
, pp. 2561-2566
-
-
Milton, N.G.N.1
Mayor, N.P.2
Rawlinson, J.3
-
53
-
-
68849126894
-
Prion protein oligomers in Creutzfeldt-Jakob disease detected by gel-filtration centrifuge columns
-
Minaki H., Sasaki K., Honda H., Iwaki T. Prion protein oligomers in Creutzfeldt-Jakob disease detected by gel-filtration centrifuge columns. Neuropathology 2009, 29:536-542.
-
(2009)
Neuropathology
, vol.29
, pp. 536-542
-
-
Minaki, H.1
Sasaki, K.2
Honda, H.3
Iwaki, T.4
-
54
-
-
79960449390
-
Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment
-
Nanga R.P.R., Brender J.R., Vivekanandan S., Ramamoorthy A. Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment. Biochimica et Biophysica Acta 2011, 1808:2337-2342.
-
(2011)
Biochimica et Biophysica Acta
, vol.1808
, pp. 2337-2342
-
-
Nanga, R.P.R.1
Brender, J.R.2
Vivekanandan, S.3
Ramamoorthy, A.4
-
55
-
-
67650533782
-
Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy
-
Nanga R.P.R., Brender J.R., Xu J., Hartman K., Subramanian V., Ramamoorthy A. Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy. Journal of the American Chemical Society 2009, 131:8252-8261.
-
(2009)
Journal of the American Chemical Society
, vol.131
, pp. 8252-8261
-
-
Nanga, R.P.R.1
Brender, J.R.2
Xu, J.3
Hartman, K.4
Subramanian, V.5
Ramamoorthy, A.6
-
56
-
-
57049174009
-
Structures of rat and human islet amyloid polypeptide IAPP (1-19) in micelles by NMR spectroscopy
-
Nanga R.P.R., Brender J.R., Xu J., Veglia G., Ramamoorthy A. Structures of rat and human islet amyloid polypeptide IAPP (1-19) in micelles by NMR spectroscopy. Biochemistry 2008, 47:12689-12697.
-
(2008)
Biochemistry
, vol.47
, pp. 12689-12697
-
-
Nanga, R.P.R.1
Brender, J.R.2
Xu, J.3
Veglia, G.4
Ramamoorthy, A.5
-
57
-
-
79953720607
-
Heterogeneous amylin fibril growth mechanisms imaged by total internal reflection fluorescence microscopy
-
Patil S.M., Mehta A., Jha S., Alexandrescu A.T. Heterogeneous amylin fibril growth mechanisms imaged by total internal reflection fluorescence microscopy. Biochemistry 2011, 50:2808-2819.
-
(2011)
Biochemistry
, vol.50
, pp. 2808-2819
-
-
Patil, S.M.1
Mehta, A.2
Jha, S.3
Alexandrescu, A.T.4
-
58
-
-
0016651874
-
Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues
-
Patthy L., Smith E.L. Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues. Journal of Biological Chemistry 1975, 250:557-564.
-
(1975)
Journal of Biological Chemistry
, vol.250
, pp. 557-564
-
-
Patthy, L.1
Smith, E.L.2
-
59
-
-
60749096770
-
Highly efficient and low-cost purification of lysozyme: a novel tris(hydroxymethyl)aminomethane immobilized affinity column
-
Quan L., Cao Q., Li Z., Li N., Li K., Liu F. Highly efficient and low-cost purification of lysozyme: a novel tris(hydroxymethyl)aminomethane immobilized affinity column. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2009, 877:594-598.
-
(2009)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.877
, pp. 594-598
-
-
Quan, L.1
Cao, Q.2
Li, Z.3
Li, N.4
Li, K.5
Liu, F.6
-
60
-
-
78649814620
-
Beta-cell selective K(ATP)-channel activation protects beta-cells and human islets from human islet amyloid polypeptide induced toxicity
-
Ritzel R.A., Jayasinghe S., Hansen J.B., Sturis J., Langen R., Butler P.C. Beta-cell selective K(ATP)-channel activation protects beta-cells and human islets from human islet amyloid polypeptide induced toxicity. Regulatory Peptides 2010, 165:158-162.
-
(2010)
Regulatory Peptides
, vol.165
, pp. 158-162
-
-
Ritzel, R.A.1
Jayasinghe, S.2
Hansen, J.B.3
Sturis, J.4
Langen, R.5
Butler, P.C.6
-
61
-
-
33847012626
-
Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets
-
Ritzel R.A., Meier J.J., Lin C.-Y., Veldhuis J.D., Butler P.C. Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets. Diabetes 2007, 56:65-71.
-
(2007)
Diabetes
, vol.56
, pp. 65-71
-
-
Ritzel, R.A.1
Meier, J.J.2
Lin, C.-Y.3
Veldhuis, J.D.4
Butler, P.C.5
-
62
-
-
79958754561
-
A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc
-
Salamekh S., Brender J.R., Hyung S.-J., Nanga R.P.R., Vivekanandan S., Ruotolo B.T., Ramamoorthy A. A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc. Journal of Molecular Biology 2011, 410:294-306.
-
(2011)
Journal of Molecular Biology
, vol.410
, pp. 294-306
-
-
Salamekh, S.1
Brender, J.R.2
Hyung, S.-J.3
Nanga, R.P.R.4
Vivekanandan, S.5
Ruotolo, B.T.6
Ramamoorthy, A.7
-
63
-
-
0020477045
-
Synthesis of 9-(3,4-dioxopentyl)hypoxanthine, the first arginine-directed purine derivative: an irreversible inactivator for purine nucleoside phosphorylase
-
Salamone S.J., Jordan F. Synthesis of 9-(3,4-dioxopentyl)hypoxanthine, the first arginine-directed purine derivative: an irreversible inactivator for purine nucleoside phosphorylase. Biochemistry 1982, 21:6383-6388.
-
(1982)
Biochemistry
, vol.21
, pp. 6383-6388
-
-
Salamone, S.J.1
Jordan, F.2
-
64
-
-
79952167224
-
Prion propagation and toxicity in vivo occur in two distinct mechanistic phases
-
Sandberg M.K., Al-Doujaily H., Sharps B., Clarke A.R., Collinge J. Prion propagation and toxicity in vivo occur in two distinct mechanistic phases. Nature 2011, 470:540-542.
-
(2011)
Nature
, vol.470
, pp. 540-542
-
-
Sandberg, M.K.1
Al-Doujaily, H.2
Sharps, B.3
Clarke, A.R.4
Collinge, J.5
-
65
-
-
67749097800
-
Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide
-
Smith P.E.S., Brender J.R., Ramamoorthy A. Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide. Journal of the American Chemical Society 2009, 131:4470-4478.
-
(2009)
Journal of the American Chemical Society
, vol.131
, pp. 4470-4478
-
-
Smith, P.E.S.1
Brender, J.R.2
Ramamoorthy, A.3
-
66
-
-
84869887960
-
Structural features and cytotoxicity of amyloid oligomers: implications in Alzheimer's disease and other diseases with amyloid deposits
-
in press. doi:10.1016/j.pneurobio.2012.03.002
-
Stefani, M., 2012. Structural features and cytotoxicity of amyloid oligomers: implications in Alzheimer's disease and other diseases with amyloid deposits. Progress in Neurobiology, in press. doi:10.1016/j.pneurobio.2012.03.002.
-
Progress in Neurobiology
, vol.2012
-
-
Stefani, M.1
-
68
-
-
80053898059
-
Clustering and internalization of toxic amylin oligomers in pancreatic cells require plasma membrane cholesterol
-
Trikha S., Jeremic A.M. Clustering and internalization of toxic amylin oligomers in pancreatic cells require plasma membrane cholesterol. Journal of Biological Chemistry 2011, 286:36086-36097.
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 36086-36097
-
-
Trikha, S.1
Jeremic, A.M.2
-
69
-
-
0025366838
-
Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation
-
Westermark P., Engström U., Johnson K.H., Westermark G.T., Betsholtz C. Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 1990, 87:5036-5040.
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, pp. 5036-5040
-
-
Westermark, P.1
Engström, U.2
Johnson, K.H.3
Westermark, G.T.4
Betsholtz, C.5
-
70
-
-
0032855482
-
Methodological and chemical factors affecting amyloid beta peptide amyloidogenicity
-
Zagorski M.G., Yang J., Shao H., Ma K., Zeng H., Hong A. Methodological and chemical factors affecting amyloid beta peptide amyloidogenicity. Methods in Enzymology 1999, 309:189-204.
-
(1999)
Methods in Enzymology
, vol.309
, pp. 189-204
-
-
Zagorski, M.G.1
Yang, J.2
Shao, H.3
Ma, K.4
Zeng, H.5
Hong, A.6
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