Heterogeneous amylin fibril growth mechanisms imaged by total internal reflection fluorescence microscopy

Biochemistry

Volumn 50, Issue 14, 2011, Pages 2808-2819

  Patil, Sharadrao M ^a   Mehta, Andrew ^a   Jha, Suman ^a   Alexandrescu, Andrei T ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC PH; AGGREGATE GROWTH; AGGREGATION PROCESS; CORRESPONDING SOLUTIONS; ELECTRON MICROGRAPH; FIBRIL ELONGATION; FIBRIL GROWTH; FIBRIL MORPHOLOGY; FIBRILLIZATION; FLUORESCENCE INTENSITIES; GROWTH PROCESS; INITIAL POPULATION; NUCLEATION MECHANISM; SECONDARY NUCLEATION; THIOFLAVIN T; TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY; TYPE-2 DIABETES;

AMINO ACIDS; FLUORESCENCE; FLUORESCENCE MICROSCOPY; GRANULATION; NUCLEATION; POPULATION STATISTICS; REFRACTIVE INDEX; SEED;

AGGLOMERATION;

AMYLIN; AMYLOID; HISTIDINE; OLIGOMER; THIOFLAVINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISULFIDE BOND; ELECTRON MICROSCOPY; FIBER; FIBRILLIZATION; FLUORESCENCE MICROSCOPY; GROWTH RATE; IMAGE ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MORPHOLOGY; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN MODIFICATION; PROTEIN SECONDARY STRUCTURE; TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISULFIDES; HUMANS; HYDROGEN-ION CONCENTRATION; ISLET AMYLOID POLYPEPTIDE; KINETICS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; SOLUTIONS;

EID: 79953720607     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101908m     Document Type: Article

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