Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: Is there a critical amyloidogenic domain in human IAPP?

Journal of Molecular Biology

Volumn 355, Issue 2, 2006, Pages 274-281

  Abedini, Andisheh ^a   Raleigh, Daniel P ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Aggregation; Amylin; Amyloid; IAPP; Islet amyloid polypeptide

Indexed keywords

AMYLIN; AMYLOID; CONGO RED; PROLINE; THIOFLAVINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; COMPARATIVE STUDY; FOURIER TRANSFORMATION; INFRARED SPECTROSCOPY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN VARIANT; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; WILD TYPE;

RODENTIA;

EID: 28944455381     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.10.052     Document Type: Article

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